| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hiroki Hashizume, Hatsune Motonari, Kenta Yamamoto, Yoki Nakamura, Kazue Hisaoka-Nakashima, Norimitsu Moriok. Stimulation of nuclear receptor REV-ERBs alleviates monosodium iodoacetate-induced osteoarthritis pathology of mice and the induction of inflammatory molecules expression in primary cultured chondrocytes. International immunopharmacology. vol 127. 2023-12-12. PMID:38086272. |
in the current study, we found that pretreatment with the rev-erb agonist sr9009 significantly blocked the increases in inflammatory molecules [(matrix metalloproteinase (mmp) 3, mmp9, and mmp13] and cytokines (interleukin-1β and tumor necrosis factor) in primary cultured chondrocytes following treatment with lipopolysaccharide. |
2023-12-12 |
2023-12-17 |
mouse |
| Ye Ji Kim, Zinah Hilal Khaleel, Myeongji Jin, Jo Woon Yi Lee, Seongchan Park, Seongmin Ga, Nam Hyeong Kim, Deok Hyang Sa, Eun Sung Kang, Seul Hee Han, Ji Yeun Lee, Hyo Jung Ku, Sang-Wook Kim, Ki Yong Kim, Jeong Euy Park, Yong Ho Kim, Bok-Soo Le. Mechanistic insights into the anti-restenotic effects of HSP27 and HO1 modulated by reconstituted HDL on neointimal hyperplasia. Scientific reports. vol 13. issue 1. 2023-12-12. PMID:38087008. |
additionally, rhdl treatment led to decreased infiltration of leukocytes and downregulated the expression of matrix metallopeptidase 9 (mmp9) in the neointimal area. |
2023-12-12 |
2023-12-17 |
rat |
| Xiangrong Liu, Wenqi Bai, Jianrong Li, Jinfeng Ma, Yan Liu, Zhixiang Wang, Linjie Hu, Zheng Li, Dimitri Papukashvili, Nino Rcheulishvili, Fusheng Wang, Xiaoqing L. MLLT11 siRNA Inhibits the Migration and Promotes the Apoptosis of MDA-MB-231 Breast Cancer Cells. The breast journal. vol 2023. 2023-12-11. PMID:38075552. |
moreover, cell migration and invasion, as well as the protein levels of phosphatidylinositol 3-kinase (pi3k), akt, matrix metalloproteinase (mmp) 2, and mmp9, were significantly lower in the groups treated with sirna while the apoptosis was augmented. |
2023-12-11 |
2023-12-17 |
Not clear |
| Xiaoyan Shen, Xiaoping Xie, Qi Wu, Feng Shi, Yuanyang Chen, Shun Yuan, Kai Xing, Xu Li, Qingyi Zhu, Bowen Li, Zhiwei Wan. S-adenosylmethionine attenuates angiotensin II-induced aortic dissection formation by inhibiting vascular smooth muscle cell phenotypic switch and autophagy. Biochemical pharmacology. vol 219. 2023-12-10. PMID:38065291. |
meanwhile, sam also inhibited the cellular phenotypic switch, mainly by up regulating the expression levels of contractile marker proteins [α-smooth muscle actin (α-sma) and smooth muscle 22α (sm22α)] and down regulating the expression levels of synthetic marker proteins [osteoblast protein (opn), matrix metalloproteinase-2 (mmp2), and matrix metalloproteinase-9 (mmp9)]. |
2023-12-10 |
2023-12-17 |
mouse |
| Rotem Kalev-Altman, Gal Becker, Tamar Levy, Svetlana Penn, Nahum Y Shpigel, Efrat Monsonego-Ornan, Dalit Sela-Donenfel. Mmp2 Deficiency Leads to Defective Parturition and High Dystocia Rates in Mice. International journal of molecular sciences. vol 24. issue 23. 2023-12-09. PMID:38069145. |
the gelatinases subgroup of matrix metalloproteinases (mmps), mmp2 and mmp9, participate in uterine ecm remodeling throughout pregnancy and parturition. |
2023-12-09 |
2023-12-17 |
mouse |
| Koki Yoshimoto, Koichiro Maki, Taiji Adachi, Ken-Ichiro Kame. Cyclic Stretching Enhances Angiocrine Signals at Liver Bud Stage from hPSCs in 2-Dimensional Culture. Tissue engineering. Part A. 2023-12-08. PMID:38062736. |
rna sequencing revealed that the expression of genes associated with epithelial-to-mesenchymal transition, including angiocrine signals, such as hepatocyte growth factor (hgf) and matrix metallopeptidase 9 (mmp9), were increased by cms in co-cultured kdr- and kdr+ cells. |
2023-12-08 |
2023-12-17 |
human |
| Sara Zahid, Arif Malik, Suleyman Waqar, Fatima Zahid, Nusrat Tariq, Ali Imran Khawaja, Waqas Safir, Faisal Gulzar, Javeid Iqbal, Qurban Al. Countenance and implication of Β-sitosterol, Β-amyrin and epiafzelechin in nickel exposed Rat: in-silico and in-vivo approach. Scientific reports. vol 13. issue 1. 2023-12-04. PMID:38049552. |
to evaluate the ligand-protein interaction of four selected components against vascular endothelial growth factor (vegf), matrix metalloproteinase-9 (mmp9) inhibitor and interleukin-10 (il-10) molecular docking approach was applied using pyrx bioinformatics tool. |
2023-12-04 |
2023-12-10 |
rat |
| Mi Hee Kwack, Ons Ben Hamida, Min Kyu Kim, Moon Kyu Kim, Young Kwan Sun. Establishment and characterization of matched immortalized human frontal and occipital scalp dermal papilla cell lines from androgenetic alopecia. Scientific reports. vol 13. issue 1. 2023-12-04. PMID:38049592. |
furthermore, when the cells were cultured in a 3d environment mimicking in vivo conditions, the 3d cultured frontal dp cell line exhibited weaker sphere aggregation than the occipital dp cell line due to the increased expression of matrix metalloproteinase 1 (mmp1), mmp3, and mmp9. |
2023-12-04 |
2023-12-10 |
human |
| Dmitry Egorov, Irakli Kopaliani, Anne Klotzsche-von Ameln, Stephan Speier, Andreas Deusse. Mechanism of pro-MMP9 activation in co-culture of pro-inflammatory macrophages and cardiomyocytes. Experimental cell research. 2023-12-03. PMID:38043722. |
"inflamed" heart tissue is infiltrated with pro-inflammatory macrophages which extensively secrete matrix metalloproteinase 9 (mmp9), a regulator of extracellular matrix turnover. |
2023-12-03 |
2023-12-10 |
Not clear |
| Nabila Djaziri, Cindy Burel, Lilia Abbad, Zeineb Bakey, Rémi Piedagnel, Brigitte Lelong. Cleavage of periostin by MMP9 protects mice from kidney cystic disease. PloS one. vol 18. issue 12. 2023-12-01. PMID:38039285. |
the matrix metalloproteinase mmp9 influences cellular morphology and function, and plays important roles in organogenesis and disease. |
2023-12-01 |
2023-12-10 |
mouse |
| Ki Baek Lee, Xin G. Generation of Protease Inhibitory Antibodies by Functional In Vivo Selection. Methods in molecular biology (Clifton, N.J.). vol 2747. 2023-12-01. PMID:38038945. |
we validate this approach by isolation of highly selective and potent mabs inhibiting human matrix metalloproteinase 9 (mmp9). |
2023-12-01 |
2023-12-10 |
human |
| Meng Li, Panpan Wei, Kexin Li, Haole Liu, Naqash Alam, Haiwen Hou, Jie Deng, Baohui Xu, Enqi Liu, Sihai Zhao, Yankui L. The incidence rate and histological characteristics of intimal hyperplasia in elastase-induced experimental abdominal aortic aneurysms in mice. Animal models and experimental medicine. 2023-11-28. PMID:38017222. |
local cell-secreted matrix metalloproteinases (mmp) 2 was highly expressed in all ih lesions, but mmp9 was only overexpressed in severe lesions. |
2023-11-28 |
2023-12-07 |
mouse |
| Vishal Musale, Colin E Murdoch, Ayman K Banah, Annie Hasib, Chandani K Hennayake, Bo Dong, Chim C Lang, David H Wasserman, Li Kan. Extracellular Matrix Abnormalities Contribute to Cardiac Insulin Resistance and Associated Dysfunction in Diet-induced Obese Mice. bioRxiv : the preprint server for biology. 2023-11-28. PMID:38014154. |
increased collagen deposition by genetic deletion of matrix metalloproteinase 9 (mmp9) exacerbated cardiac insulin resistance and decreased hyaluronan deposition by treatment with pegylated human recombinant hyaluronidase ph20 (pegph20) improved cardiac insulin resistance in obese mice. |
2023-11-28 |
2023-11-29 |
mouse |
| Inga Duerig, Ekaterina Pylaeva, Irem Ozel, Sami Wainwright, Ilona Thiel, Sharareh Bordbari, Maksim Domnich, Elena Siakaeva, Antonia Lakomek, Felicia Toppe, Carolin Schleupner, Urban Geisthoff, Stephan Lang, Freya Droege, Jadwiga Jablonsk. Nonfunctional TGF-β/ALK1/ENG signaling pathway supports neutrophil proangiogenic activity in hereditary hemorrhagic telangiectasia. Journal of leukocyte biology. vol 114. issue 6. 2023-11-25. PMID:37555392. |
elevated proangiogenic activity of hht neutrophils is mediated by the increased spontaneous degranulation of gelatinase granules, resulting in high release of matrix-degrading matrix metalloproteinase 9 (mmp9). |
2023-11-25 |
2023-11-28 |
Not clear |
| Eman A Toraih, Mohamed H Hussein, Essam Al Ageeli, Mohamad Ellaban, Shahd W Kattan, Krzysztof Moroz, Manal S Fawzy, Emad Kandi. Matrix Metalloproteinase 9/microRNA-145 Ratio: Bridging Genomic and Immunological Variabilities in Thyroid Cancer. Biomedicines. vol 11. issue 11. 2023-11-25. PMID:38001954. |
matrix metalloproteinase 9 (mmp9) and microrna-145 (mir-145) have emerged as essential biomarkers in thyroid cancer progression and metastasis. |
2023-11-25 |
2023-11-28 |
Not clear |
| Flobater I Gawargi, Paras K Mishr. Deciphering MMP9's Dual Role in Regulating SOD3 through Protein-Protein Interaction. Canadian journal of physiology and pharmacology. 2023-11-22. PMID:37992301. |
although the collagenase enzyme activity of matrix metalloproteinase-9 (mmp9) has been extensively explored, insights into its non-enzymatic activity remains unclear. |
2023-11-22 |
2023-11-29 |
Not clear |
| Shujun Lin, Wenshan Lin, Zhiqing Zhong, Hongzhen Zhong, Tianbiao Zhou, Wenjuan Wen. The Expression and Molecular Mechanisms of Matrix Metalloproteinase-9 and Vascular Endothelial Growth Factor in Renal Interstitial Fibrosis in Rats. Current molecular medicine. 2023-11-08. PMID:37936436. |
to explore a new approach for the treatment of renal interstitial fibrosis (rif), we detected the expression of matrix metalloproteinase-9 (mmp9) and vascular endothelial growth factor (vegf). |
2023-11-08 |
2023-11-20 |
rat |
| Tatyana Gebauer, Radek Gebauer, Petr Císař, Jan Černý, Deepali Rahi Roy, Mahyar Zare, Marieke Verleih, Vlastimil Stejskal, Alexander Reb. Are bold-shy personalities of European perch (Perca fluviatilis) linked to stress tolerance and immunity? A scope of harnessing fish behavior in aquaculture. Fish & shellfish immunology. vol 143. 2023-11-02. PMID:37890737. |
these expression differences between stimulated bold and shy perch were generally modest, except for the genes encoding the complement component c3 and the matrix metallopeptidase mmp9. |
2023-11-02 |
2023-11-08 |
Not clear |
| Ruoqing Cai, Caitlin M Tressler, Menglin Cheng, Kanchan Sonkar, Zheqiong Tan, Santosh Kumar Paidi, Vinay Ayyappan, Ishan Barman, Kristine Glund. Primary breast tumor induced extracellular matrix remodeling in premetastatic lungs. Scientific reports. vol 13. issue 1. 2023-10-31. PMID:37903851. |
premetastatic lungs contained significantly upregulated collagen (col) col4a5, matrix metalloproteinases (mmps) mmp9 and mmp14, and decreased levels of mmp13 and lysyl oxidase (lox) as compared to control lungs. |
2023-10-31 |
2023-11-08 |
mouse |
| Pan Fan, Huanhuan Ye, Chenhua Zhu, Hu Xi. Exploring the pathogenesis of osteomyelitis accompanied by diabetic foot ulcers using microarray data analysis. Medicine. vol 102. issue 43. 2023-10-31. PMID:37904457. |
the 12 most essential key genes were later screened by cytohubba, including matrix metalloproteinases (mmp) 1, mmp3, mmp9, il8, c-x-c chemokine receptor (cxcr) 2, c-x-c motif chemokine ligand (cxcl) 9, cxcl10, cxcl13, fcgr3b, il1b, lcn2, s100a12. |
2023-10-31 |
2023-11-08 |
Not clear |