| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S Lepidi, R D Kenagy, E W Raines, E S Chiu, A Chait, R Ross, A W Clowe. MMP9 production by human monocyte-derived macrophages is decreased on polymerized type I collagen. Journal of vascular surgery. vol 34. issue 6. 2002-01-18. PMID:11743569. |
the production of matrix metalloproteinases (mmps), such as mmp9, by macrophages may be a critical factor in the rupture of unstable atherosclerotic plaques and aortic aneurysms. |
2002-01-18 |
2023-08-12 |
human |
| S Lepidi, R D Kenagy, E W Raines, E S Chiu, A Chait, R Ross, A W Clowe. MMP9 production by human monocyte-derived macrophages is decreased on polymerized type I collagen. Journal of vascular surgery. vol 34. issue 6. 2002-01-18. PMID:11743569. |
therefore, we studied the role of matrix and soluble cytokines in the regulation of monocyte/macrophage expression of mmp9. |
2002-01-18 |
2023-08-12 |
human |
| J F Maddo. Mapping the matrix metalloproteinase 9 (MMP9) gene and the BL1071 microsatellite to ovine chromosome 13 (OAR13). Animal genetics. vol 32. issue 5. 2002-01-17. PMID:11683731. |
mapping the matrix metalloproteinase 9 (mmp9) gene and the bl1071 microsatellite to ovine chromosome 13 (oar13). |
2002-01-17 |
2023-08-12 |
Not clear |
| M H Rabinowitz, R C Andrews, J D Becherer, D M Bickett, D G Bubacz, J G Conway, D J Cowan, M Gaul, K Glennon, M H Lambert, M A Leesnitzer, D L McDougald, M L Moss, D L Musso, M C Rizzoli. Design of selective and soluble inhibitors of tumor necrosis factor-alpha converting enzyme (TACE). Journal of medicinal chemistry. vol 44. issue 24. 2001-12-12. PMID:11708926. |
inhibitors containing these arginine mimetics were found to have increased solubility in simulated gastric fluid (sgf) relative to 1, allowing for the incorporation of lipophilic p1' side chains which had the effect of retaining potent tace inhibition, but reducing potency against matrix metalloproteases (mmps) thus increasing overall selectivity against mmp1, mmp3, and mmp9. |
2001-12-12 |
2023-08-12 |
rat |
| J C Rodriguez-Manzaneque, T F Lane, M A Ortega, R O Hynes, J Lawler, M L Iruela-Arisp. Thrombospondin-1 suppresses spontaneous tumor growth and inhibits activation of matrix metalloproteinase-9 and mobilization of vascular endothelial growth factor. Proceedings of the National Academy of Sciences of the United States of America. vol 98. issue 22. 2001-12-04. PMID:11606713. |
interestingly, absence of tsp1 resulted in increased association of vascular endothelial growth factor (vegf) with its receptor vegfr2 and higher levels of active matrix metalloproteinase-9 (mmp9), a molecule previously shown to facilitate both angiogenesis and tumor invasion. |
2001-12-04 |
2023-08-12 |
mouse |
| J E Puzas, J M Landeau, R Tallents, J Albright, E M Schwarz, R Landesber. Degradative pathways in tissues of the temporomandibular joint. Use of in vitro and in vivo models to characterize matrix metalloproteinase and cytokine activity. Cells, tissues, organs. vol 169. issue 3. 2001-10-11. PMID:11455120. |
we describe the presence of a matrix metalloproteinase, mmp9 (92-kd gelatinase), in tmj disc and articular cells that likely function in the degradative process. |
2001-10-11 |
2023-08-12 |
mouse |
| F Kratz, J Drevs, G Bing, C Stockmar, K Scheuermann, P Lazar, C Unge. Development and in vitro efficacy of novel MMP2 and MMP9 specific doxorubicin albumin conjugates. Bioorganic & medicinal chemistry letters. vol 11. issue 15. 2001-10-04. PMID:11454467. |
two doxorubicin albumin conjugates (a-dp1 and a-dp2), which differ in their substrate specificity for the matrix metalloproteinases mmp2 and mmp9, were prepared by binding maleimide doxorubicin peptide derivatives to the cysteine-34 position of human serum albumin. |
2001-10-04 |
2023-08-12 |
human |
| P J Pöllänen, P J Karhunen, J Mikkelsson, P Laippala, M Perola, A Penttilä, K M Mattila, T Koivula, T Lehtimäk. Coronary artery complicated lesion area is related to functional polymorphism of matrix metalloproteinase 9 gene: an autopsy study. Arteriosclerosis, thrombosis, and vascular biology. vol 21. issue 9. 2001-10-04. PMID:11557670. |
matrix metalloproteinase 9 (mmp9) is expressed in human atherosclerotic plaques, and the protein is localized in human coronary atherosclerotic lesions. |
2001-10-04 |
2023-08-12 |
human |
| Y Soini, J Satta, M Määttä, H Autio-Harmaine. Expression of MMP2, MMP9, MT1-MMP, TIMP1, and TIMP2 mRNA in valvular lesions of the heart. The Journal of pathology. vol 194. issue 2. 2001-06-21. PMID:11400152. |
this study was undertaken to investigate the mrna synthesis of mmp2, mmp9, membrane-type 1 (mt1)-mmp, and matrix metalloproteinase inhibitors timp1 and timp2 by in situ hybridization in a set of heart mitral and aortic valves operatively removed due to degenerative or inflammatory valvular diseases. |
2001-06-21 |
2023-08-12 |
Not clear |
| Y Soini, J Satta, M Määttä, H Autio-Harmaine. Expression of MMP2, MMP9, MT1-MMP, TIMP1, and TIMP2 mRNA in valvular lesions of the heart. The Journal of pathology. vol 194. issue 2. 2001-06-21. PMID:11400152. |
the results show that matrix metalloproteinases mmp2 and mmp9, and matrix metalloproteinase inhibitors timp1 and timp2 mrnas are synthesized in diseased valves and suggest that they may contribute to matrix remodelling in valvular disease. |
2001-06-21 |
2023-08-12 |
Not clear |
| John Martin, Lisa Eynstone, Malcolm Davies, Robert Steadma. Induction of metalloproteinases by glomerular mesangial cells stimulated by proteins of the extracellular matrix. Journal of the American Society of Nephrology : JASN. vol 12. issue 1. 2001-05-24. PMID:11134254. |
the present study, therefore, investigated the effect of different matrix components on the adherence of hmc and on their secretion and activation of the gelatinases mmp2 and mmp9. |
2001-05-24 |
2023-08-12 |
human |
| John Martin, Lisa Eynstone, Malcolm Davies, Robert Steadma. Induction of metalloproteinases by glomerular mesangial cells stimulated by proteins of the extracellular matrix. Journal of the American Society of Nephrology : JASN. vol 12. issue 1. 2001-05-24. PMID:11134254. |
the results demonstrate that specific matrix components increased the secretion of mmp2 and mmp9 from hmc. |
2001-05-24 |
2023-08-12 |
human |
| R L Robker, D L Russell, S Yoshioka, S C Sharma, J P Lydon, B W O'Malley, L L Espey, J S Richard. Ovulation: a multi-gene, multi-step process. Steroids. vol 65. issue 10-11. 2001-03-29. PMID:11108860. |
the matrix metalloproteinases (mmps: mmp2, mmp9, and mmp13) appear to be expressed in ovaries of prko mice in a manner similar to that in their wild-type littermates. |
2001-03-29 |
2023-08-12 |
mouse |
| K Harimaya, K Tanaka, Y Matsumoto, H Sato, S Matsuda, Y Iwamot. Antioxidants inhibit TNFalpha-induced motility and invasion of human osteosarcoma cells: possible involvement of NFkappaB activation. Clinical & experimental metastasis. vol 18. issue 2. 2001-03-29. PMID:11235987. |
tnfalpha treatment also induced tumor cell motility, adhesion to laminin, the expression of matrix metalloproteinase 9 (mmp9), and the nuclear translocation of nuclear factor kappab (nfkappab) in the osteosarcoma cells. |
2001-03-29 |
2023-08-12 |
human |
| G E Terp, I T Christensen, F S Jørgense. Structural differences of matrix metalloproteinases. Homology modeling and energy minimization of enzyme-substrate complexes. Journal of biomolecular structure & dynamics. vol 17. issue 6. 2000-12-28. PMID:10949161. |
a general approach to the homology modeling of matrix metalloproteinases, exemplified by the modeling of mmp2, mmp9, mmp12 and mmp14 is described. |
2000-12-28 |
2023-08-12 |
Not clear |
| T Horikawa, T Yoshizaki, T S Sheen, S Y Lee, M Furukaw. Association of latent membrane protein 1 and matrix metalloproteinase 9 with metastasis in nasopharyngeal carcinoma. Cancer. vol 89. issue 4. 2000-09-07. PMID:10951332. |
matrix metalloproteinase 9 (mmp9), one of the mmp families, degrades type iv collagen, a major component of extracellular matrix and is believed to be crucial for cancer invasion and metastasis. |
2000-09-07 |
2023-08-12 |
Not clear |
| S E Wert, M Yoshida, A M LeVine, M Ikegami, T Jones, G F Ross, J H Fisher, T R Korfhagen, J A Whitset. Increased metalloproteinase activity, oxidant production, and emphysema in surfactant protein D gene-inactivated mice. Proceedings of the National Academy of Sciences of the United States of America. vol 97. issue 11. 2000-06-30. PMID:10801980. |
these abnormalities were associated with increased activity of the matrix metalloproteinases, mmp2 and mmp9, and immunostaining for mmp9 and mmp12 in alveolar macrophages. |
2000-06-30 |
2023-08-12 |
mouse |
| G Dew, G Murphy, H Stanton, R Vallon, P Angel, J J Reynolds, R M Hembr. Localisation of matrix metalloproteinases and TIMP-2 in resorbing mouse bone. Cell and tissue research. vol 299. issue 3. 2000-06-06. PMID:10772252. |
in uncultured tissues the bone surfaces had isolated foci of collagenase staining, and cartilage matrix stained for gelatinase b (mmp9) and timp-2. |
2000-06-06 |
2023-08-12 |
mouse |
| T Yoshizaki, H Sato, S Murono, J S Pagano, M Furukaw. Matrix metalloproteinase 9 is induced by the Epstein-Barr virus BZLF1 transactivator. Clinical & experimental metastasis. vol 17. issue 5. 2000-02-07. PMID:10651310. |
type iv collagenases, matrix metalloproteinase (mmp) 2 and mmp9 are implicated in tumor invasion and metastasis. |
2000-02-07 |
2023-08-12 |
Not clear |
| N Kanbe, A Tanaka, M Kanbe, A Itakura, M Kurosawa, H Matsud. Human mast cells produce matrix metalloproteinase 9. European journal of immunology. vol 29. issue 8. 1999-09-14. PMID:10458779. |
thus, these findings indicate that human mast cells can produce mmp9, which might contribute to extracellular matrix degradation and absorption in the process of allergic and nonallergic responses. |
1999-09-14 |
2023-08-12 |
human |