| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| T Koujitani, K Yasuhara, T Ikeda, T Imazawa, T Tamura, K Toyosawa, A Shimada, M Hirose, K Mitsumor. Sequential observation of 2,6-dimethylaniline-induced nasal lesions in a rat two-stage nasal carcinogenesis model after initiation with N-bis(2-hydroxypropyl) nitrosamine. The Journal of veterinary medical science. vol 62. issue 7. 2000-12-07. PMID:10945294. |
these nasal lesions were mostly evident in the olfactory mucosa in the nasal cavity, and their severity and/or incidences, other than atrophy of bowman's glands, increased with the treatment period. |
2000-12-07 |
2023-08-12 |
rat |
| M Dahlin, U Bergman, B Jansson, E Björk, E Britteb. Transfer of dopamine in the olfactory pathway following nasal administration in mice. Pharmaceutical research. vol 17. issue 6. 2000-12-07. PMID:10955850. |
transfer of dopamine in the olfactory pathway following nasal administration in mice. |
2000-12-07 |
2023-08-12 |
mouse |
| M Dahlin, U Bergman, B Jansson, E Björk, E Britteb. Transfer of dopamine in the olfactory pathway following nasal administration in mice. Pharmaceutical research. vol 17. issue 6. 2000-12-07. PMID:10955850. |
the aim of the study was to investigate whether dopamine is transferred along the olfactory pathway to the brain following nasal administration to mice. |
2000-12-07 |
2023-08-12 |
mouse |
| M Andersen, R Sarangapani, R Gentry, H Clewell, T Covington, C B Frederic. Application of a hybrid CFD-PBPK nasal dosimetry model in an inhalation risk assessment: an example with acrylic acid. Toxicological sciences : an official journal of the Society of Toxicology. vol 57. issue 2. 2000-11-21. PMID:11006361. |
the available inhalation toxicity information for acrylic acid (aa) suggests that lesions to the nasal cavity, specifically olfactory degeneration, are the most sensitive end point for developing a reference concentration (rfc). |
2000-11-21 |
2023-08-12 |
mouse |
| J M Klossek, J P Fontane. [Rhino-sinus polyposis]. La Revue du praticien. vol 50. issue 14. 2000-11-17. PMID:11068617. |
nasal obstruction and olfactory disorders are the main symptoms due to the presence of bilateral polyps in the nasal cavities. |
2000-11-17 |
2023-08-12 |
Not clear |
| R B Conolly, P D Lilly, J S Kimbel. Simulation modeling of the tissue disposition of formaldehyde to predict nasal DNA-protein cross-links in Fischer 344 rats, rhesus monkeys, and humans. Environmental health perspectives. vol 108 Suppl 5. 2000-11-16. PMID:11036001. |
anatomically accurate, computational fluid dynamics models of the nasal airways of f344 rats, rhesus monkeys, and humans were used to predict the regional flux of formaldehyde to the respiratory and olfactory mucosa. |
2000-11-16 |
2023-08-12 |
human |
| K K Booth, L S Kat. Role of the vomeronasal organ in neonatal offspring recognition in sheep. Biology of reproduction. vol 63. issue 3. 2000-11-13. PMID:10952943. |
one group of eight ewes (procaine) were made anosmic by irrigation of the nasal olfactory apparatus with a zinc sulphate procaine solution. |
2000-11-13 |
2023-08-12 |
Not clear |
| I Savic, H Berglun. Right-nostril dominance in discrimination of unfamiliar, but not familiar, odours. Chemical senses. vol 25. issue 5. 2000-11-07. PMID:11015323. |
seventy-one right-handed healthy subjects (age 21-49 years, 40 females) with normal nasal anatomy and olfactory thresholds participated. |
2000-11-07 |
2023-08-12 |
human |
| K Ebino, R Lemus, M H Karo. The importance of the diluent for airway transport of toluene diisocyanate following intranasal dosing of mice. Inhalation toxicology. vol 11. issue 3. 2000-10-30. PMID:10380165. |
the nasal passages, upper pharynx, trachea, lungs, and olfactory bulbs of each animal were examined with hematoxylin-eosin and immunohistochemical staining, the latter using a rabbit anti-tdi antiserum. |
2000-10-30 |
2023-08-12 |
mouse |
| S Haruna, N Otori, H Moriyama, M Kami. [Efficacy of endoscopic transethmoidal.transsphenoidal surgery for pituitary tumors]. Nihon Jibiinkoka Gakkai kaiho. vol 103. issue 7. 2000-10-26. PMID:10946551. |
corrective surgery can be performed on an outpatient basis early after the initial operation to correct postoperative deformities of the nasal paranasal cavities, which might later cause nasal obstruction or an olfactory disturbance. |
2000-10-26 |
2023-08-12 |
Not clear |
| M Damm, H E Eckel, M Streppel, M Jungehülsing, E Stenner. [Dependence of uni- and bilateral olfactory capacity on nasal airflow in patients with chronic rhinosinusitis]. HNO. vol 48. issue 6. 2000-10-19. PMID:10929224. |
[dependence of uni- and bilateral olfactory capacity on nasal airflow in patients with chronic rhinosinusitis]. |
2000-10-19 |
2023-08-12 |
Not clear |
| S J Rehorek, B T Firth, M N Hutchinso. The structure of the nasal chemosensory system in squamate reptiles. 1. The olfactory organ, with special reference to olfaction in geckos. Journal of biosciences. vol 25. issue 2. 2000-10-16. PMID:10878858. |
the olfactory mucosa of two gekkotan species (christinus marmoratus and strophurus intermedius) is spread over a large area of the nasal cavity. |
2000-10-16 |
2023-08-12 |
Not clear |
| P R Kramer, G Guerrero, R Krishnamurthy, P J Mitchell, S Wra. Ectopic expression of luteinizing hormone-releasing hormone and peripherin in the respiratory epithelium of mice lacking transcription factor AP-2alpha. Mechanisms of development. vol 94. issue 1-2. 2000-10-10. PMID:10842061. |
in the nasal placode ap-2alpha expression delineates presumptive respiratory epithelia from olfactory epithelia, with ap-2alpha expression restricted to the anterior region of the respiratory epithelium (absent from the olfactory epithelium) at later stages. |
2000-10-10 |
2023-08-12 |
mouse |
| P R Kramer, G Guerrero, R Krishnamurthy, P J Mitchell, S Wra. Ectopic expression of luteinizing hormone-releasing hormone and peripherin in the respiratory epithelium of mice lacking transcription factor AP-2alpha. Mechanisms of development. vol 94. issue 1-2. 2000-10-10. PMID:10842061. |
to address the role ap-2alpha plays in differentiation of cell groups in the nasal placode, the spatiotemporal expression pattern of four markers normally associated with olfactory epithelial structures was analyzed in mice lacking ap-2alpha. |
2000-10-10 |
2023-08-12 |
mouse |
| P R Kramer, G Guerrero, R Krishnamurthy, P J Mitchell, S Wra. Ectopic expression of luteinizing hormone-releasing hormone and peripherin in the respiratory epithelium of mice lacking transcription factor AP-2alpha. Mechanisms of development. vol 94. issue 1-2. 2000-10-10. PMID:10842061. |
these results indicate that ap-2alpha is not essential for the separation of the olfactory and respiratory epithelium from the nasal placode and is consistent with ap-2alpha preventing recapitulation of developmental programs within the respiratory epithelium that lead to expression of lhrh and peripherin phenotypes. |
2000-10-10 |
2023-08-12 |
mouse |
| T Katagiri, T Takeuchi, T Mine, T Noguchi, T Nishizawa, S Yamamoto, M Okudaira, T Matsushim. Chronic inhalation toxicity and carcinogenicity studies of 3-chloro-2-methylpropene in BDF1 mice. Industrial health. vol 38. issue 3. 2000-09-19. PMID:10943079. |
in the nasal cavity, eosinophilic exudate associated with atrophy of olfactory epithelia, respiratory metaplasia of olfactory epithelia and olfactory gland, and eosinophilic changes in respiratory and olfactory epithelia were increased in both sexes. |
2000-09-19 |
2023-08-12 |
mouse |
| I Boggian, E Buzzacaro, A Calistri, P Calvi, A Cavaggioni, C Mucignat-Caretta, G Pal. Asymptomatic herpes simplex type 1 virus infection of the mouse brain. Journal of neurovirology. vol 6. issue 4. 2000-09-19. PMID:10951554. |
time course and distribution of the infection in the brain are demonstrated, (i) by titration of the nasal tissue and olfactory bulbs for 16 days post-infection (p.i. |
2000-09-19 |
2023-08-12 |
mouse |
| I Boggian, E Buzzacaro, A Calistri, P Calvi, A Cavaggioni, C Mucignat-Caretta, G Pal. Asymptomatic herpes simplex type 1 virus infection of the mouse brain. Journal of neurovirology. vol 6. issue 4. 2000-09-19. PMID:10951554. |
and no replicating virus on day 16 p. i.; (ii) expression in the brain of the lac z reporter gene of hsv-1 strain sc16-deltaus5-lac z consistent with a central spread of the virus through the central olfactory pathways and the trigeminal system as described in acute hsv-1 encephalitis models; (iii) pcr amplifications of a segment of the thymidine kinase gene (hsv-tk) showing the persistence of viral genome in the nasal tissue and olfactory bulbs after clearance of infectious virus. |
2000-09-19 |
2023-08-12 |
mouse |
| J T Kelly, A K Prasad, A S Wexle. Detailed flow patterns in the nasal cavity. Journal of applied physiology (Bethesda, Md. : 1985). vol 89. issue 1. 2000-08-21. PMID:10904068. |
the human nasal cavity filters and conditions inspired air while providing olfactory function. |
2000-08-21 |
2023-08-12 |
human |
| P R Kramer, S Wra. Novel gene expressed in nasal region influences outgrowth of olfactory axons and migration of luteinizing hormone-releasing hormone (LHRH) neurons. Genes & development. vol 14. issue 14. 2000-08-16. PMID:10898796. |
novel gene expressed in nasal region influences outgrowth of olfactory axons and migration of luteinizing hormone-releasing hormone (lhrh) neurons. |
2000-08-16 |
2023-08-12 |
Not clear |