| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J L Mattsso. Ototoxicity: an argument for evaluation of the cochlea in safety testing in animals. Toxicologic pathology. vol 28. issue 1. 2000-03-06. PMID:10669000. |
although histopathologic sections are routinely taken from the eye and the optic nerve and tract and most studies include at least 1 section through the nasal cavity and olfactory mucosa, the cochlea is not histopathologically examined in routine toxicity studies. |
2000-03-06 |
2023-08-12 |
human |
| O Ardouin, R Legouis, L Fasano, B David-Watine, H Korn, J Hardelin, C Peti. Characterization of the two zebrafish orthologues of the KAL-1 gene underlying X chromosome-linked Kallmann syndrome. Mechanisms of development. vol 90. issue 1. 2000-02-28. PMID:10585565. |
onward, in the presumptive olfactory bulbs, whereas kal1.2 transcript is only detected, from 48 h.p.f., in the epithelium of the nasal cavity. |
2000-02-28 |
2023-08-12 |
human |
| K Nibu, G Li, X Zhang, N E Rawson, D Restrepo, K Kaga, L D Lowry, W M Keane, J L Rothstei. Olfactory neuron-specific expression of NeuroD in mouse and human nasal mucosa. Cell and tissue research. vol 298. issue 3. 2000-02-09. PMID:10639731. |
olfactory neuron-specific expression of neurod in mouse and human nasal mucosa. |
2000-02-09 |
2023-08-12 |
mouse |
| K Nibu, G Li, X Zhang, N E Rawson, D Restrepo, K Kaga, L D Lowry, W M Keane, J L Rothstei. Olfactory neuron-specific expression of NeuroD in mouse and human nasal mucosa. Cell and tissue research. vol 298. issue 3. 2000-02-09. PMID:10639731. |
human olfactory neuroepithelium (oe) is situated within the olfactory cleft of the nasal cavity and has the characteristic property of continually regenerating neurons during the lifetime of the individual. |
2000-02-09 |
2023-08-12 |
mouse |
| K Nibu, G Li, X Zhang, N E Rawson, D Restrepo, K Kaga, L D Lowry, W M Keane, J L Rothstei. Olfactory neuron-specific expression of NeuroD in mouse and human nasal mucosa. Cell and tissue research. vol 298. issue 3. 2000-02-09. PMID:10639731. |
thus, to better understand neurogenesis in human oe, we studied the expression of olfactory marker protein (omp), trkb and neurod in human nasal biopsies and autopsy specimens and compared these data with those obtained from normal and regenerating mouse oe. |
2000-02-09 |
2023-08-12 |
mouse |
| J F Hardisty, R H Garman, J R Harkema, L G Lomax, K T Morga. Histopathology of nasal olfactory mucosa from selected inhalation toxicity studies conducted with volatile chemicals. Toxicologic pathology. vol 27. issue 6. 2000-02-03. PMID:10588541. |
histopathology of nasal olfactory mucosa from selected inhalation toxicity studies conducted with volatile chemicals. |
2000-02-03 |
2023-08-12 |
rat |
| C Eriksson, U Bergman, A Franzén, M Sjöblom, E B Britteb. Transfer of some carboxylic acids in the olfactory system following intranasal administration. Journal of drug targeting. vol 7. issue 2. 2000-02-02. PMID:10617298. |
thin layer chromatography of supernatants from the ipsilateral olfactory bulbs of mice given [14c]benzoic acid by nasal instillation indicated that the radioactivity in the bulbs represented unchanged compound. |
2000-02-02 |
2023-08-12 |
mouse |
| C H Hawkes, B C Shephard, S E Danie. Is Parkinson's disease a primary olfactory disorder? QJM : monthly journal of the Association of Physicians. vol 92. issue 8. 2000-02-01. PMID:10627864. |
the olfactory vector hypothesis suggests that the causative agent for ipd enters the brain via the nasal route, but the reason for olfactory dysfunction may be more subtle. |
2000-02-01 |
2023-08-12 |
Not clear |
| S K Kritas, M B Pensaert, H J Nauwynck, S C Kyriaki. Neural invasion of two virulent suid herpesvirus 1 strains in neonatal pigs with or without maternal immunity. Veterinary microbiology. vol 69. issue 3. 2000-01-19. PMID:10512040. |
the invasion of the strains was examined in the nasal mucosa and in three neuronal levels of the trigeminal nervous pathway as well as in three levels of the olfactory nervous pathway by virus titration and immunohistochemistry (ihc). |
2000-01-19 |
2023-08-12 |
Not clear |
| K Fukazawa, M Fujii, S Tomofuji, H Ogasawara, W Seo, M Sakagam. [Local injection of dexamethasone acetate suspension into the nasal mucosa in cases of olfactory disturbance]. Nihon Jibiinkoka Gakkai kaiho. vol 102. issue 10. 2000-01-18. PMID:10565175. |
[local injection of dexamethasone acetate suspension into the nasal mucosa in cases of olfactory disturbance]. |
2000-01-18 |
2023-08-12 |
Not clear |
| K Fukazawa, M Fujii, S Tomofuji, H Ogasawara, W Seo, M Sakagam. [Local injection of dexamethasone acetate suspension into the nasal mucosa in cases of olfactory disturbance]. Nihon Jibiinkoka Gakkai kaiho. vol 102. issue 10. 2000-01-18. PMID:10565175. |
local injections of suspended steroid solution into the nasal mucosa were performed for 102 patients with olfactory disturbances. |
2000-01-18 |
2023-08-12 |
Not clear |
| H Baumeister, R M Gronostajski, G E Lyons, F L Margoli. Identification of NFI-binding sites and cloning of NFI-cDNAs suggest a regulatory role for NFI transcription factors in olfactory neuron gene expression. Brain research. Molecular brain research. vol 72. issue 1. 1999-12-22. PMID:10521600. |
we further demonstrate, by cloning, that all four nfi genes are expressed in the olfactory nasal mucosa. |
1999-12-22 |
2023-08-12 |
Not clear |
| K T Tisay, B Ke. The extracellular matrix modulates olfactory neurite outgrowth on ensheathing cells. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 19. issue 22. 1999-12-02. PMID:10559398. |
primary olfactory axons grow along a stereotypical pathway from the nasal cavity to the olfactory bulb through an extracellular matrix rich in laminin and heparan sulfate proteoglycans (hspgs) and bounded by the expression of chondroitin sulfate proteoglycans (cspgs). |
1999-12-02 |
2023-08-12 |
Not clear |
| D Pickuth, S H Heywang-Köbrunner, R P Spielman. Computed tomography and magnetic resonance imaging features of olfactory neuroblastoma: an analysis of 22 cases. Clinical otolaryngology and allied sciences. vol 24. issue 5. 1999-11-26. PMID:10542931. |
olfactory neuroblastoma should be suspected in all ages following identification of a mass in the superior nasal cavity demonstrating both expansile and destructive growth patterns. |
1999-11-26 |
2023-08-12 |
Not clear |
| V S Deshpande, M B Genter, C Jung, P B Desa. Characterization of lidocaine metabolism by rat nasal microsomes: implications for nasal drug delivery. European journal of drug metabolism and pharmacokinetics. vol 24. issue 2. 1999-11-22. PMID:10510747. |
in this study, we investigated the metabolism of lidocaine to its primary metabolite monoethylglycine xylidide (megx), by rat nasal olfactory and respiratory microsomes. |
1999-11-22 |
2023-08-12 |
human |
| V S Deshpande, M B Genter, C Jung, P B Desa. Characterization of lidocaine metabolism by rat nasal microsomes: implications for nasal drug delivery. European journal of drug metabolism and pharmacokinetics. vol 24. issue 2. 1999-11-22. PMID:10510747. |
these isozymes were found to be present in significant amounts in both the nasal olfactory and respiratory tissue; this is the first known report of the presence of cyp2c11 in nasal mucosae. |
1999-11-22 |
2023-08-12 |
human |
| B Biacabe, J M Norès, P Bonfil. [Analysis of olfactory disorders in aging]. Presse medicale (Paris, France : 1983). vol 28. issue 31. 1999-11-16. PMID:10554617. |
changes in the nasal cavity, particularly an alteration of the processes involved in neuron distribution in the olfactory neuroepithelium, may be involved. |
1999-11-16 |
2023-08-12 |
human |
| M I Chuah, M L Getchel. Metallothionein in olfactory mucosa of Alzheimer's disease patients and apoE-deficient mice. Neuroreport. vol 10. issue 9. 1999-11-10. PMID:10501533. |
immunostaining for metallothionein was performed on olfactory mucosa of the superior part of the nasal septum obtained from alzheimer's disease (ad) patients and normal age-matched controls. |
1999-11-10 |
2023-08-12 |
mouse |
| L Dryer, A Berghar. Odorant receptors: a plethora of G-protein-coupled receptors. Trends in pharmacological sciences. vol 20. issue 10. 1999-11-05. PMID:10498954. |
they are located in the nasal epithelium, at the ciliated surface of olfactory sensory neurones, where the initial steps of the olfactory transduction cascade occur. |
1999-11-05 |
2023-08-12 |
caenorhabditis_elegans |
| K S Wekesa, R R Anhol. Differential expression of G proteins in the mouse olfactory system. Brain research. vol 837. issue 1-2. 1999-10-21. PMID:10433994. |
in contrast, expression of g(i2) is restricted to a sub-population of olfactory neurons, along the dorsal septum and the dorsal recess of the nasal cavity, which projects primarily to medial regions of the olfactory bulb, with the exception of glomeruli adjacent to the pathway of the vomeronasal nerve. |
1999-10-21 |
2023-08-12 |
mouse |