| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Patricia T Jacobson, Lucas G Axiotakis, Brandon J Vilarello, David A Gudis, Daniel B Spielman, Nathan Yang, Carol H Yan, Zach M Soler, Joshua M Levy, Nicholas R Rowan, Alexandria L Irace, Jonathan B Overdeves. Delivering Therapy to the Olfactory Cleft: A Comparison of the Various Methods of Administering Topical Nasal Medications. Cureus. vol 16. issue 2. 2024-03-06. PMID:38445151. |
background and objective chronic rhinosinusitis (crs) is an inflammatory condition affecting the nasal mucosa, and it causes olfactory dysfunction (od) in up to 78.2% of patients. |
2024-03-06 |
2024-03-08 |
Not clear |
| Patricia T Jacobson, Lucas G Axiotakis, Brandon J Vilarello, David A Gudis, Daniel B Spielman, Nathan Yang, Carol H Yan, Zach M Soler, Joshua M Levy, Nicholas R Rowan, Alexandria L Irace, Jonathan B Overdeves. Delivering Therapy to the Olfactory Cleft: A Comparison of the Various Methods of Administering Topical Nasal Medications. Cureus. vol 16. issue 2. 2024-03-06. PMID:38445151. |
corticosteroids are the mainstay of treatment to shrink nasal polyposis, reduce inflammation, and improve olfactory function. |
2024-03-06 |
2024-03-08 |
Not clear |
| Patricia T Jacobson, Lucas G Axiotakis, Brandon J Vilarello, David A Gudis, Daniel B Spielman, Nathan Yang, Carol H Yan, Zach M Soler, Joshua M Levy, Nicholas R Rowan, Alexandria L Irace, Jonathan B Overdeves. Delivering Therapy to the Olfactory Cleft: A Comparison of the Various Methods of Administering Topical Nasal Medications. Cureus. vol 16. issue 2. 2024-03-06. PMID:38445151. |
while many delivery methods for topical nasal corticosteroids exist, there is scarce data on the efficacy of the various medication delivery methods to the olfactory cleft (oc). |
2024-03-06 |
2024-03-08 |
Not clear |
| Ghada Saad, Imen Halloul, Taghrid Tlilli, Dhia El Hak Abid, Malika Omri, Molka Chadli Chaie. Esthesioneuroblastoma presenting as syndrome of inappropriate antidiuretic hormone secretion. La Tunisie medicale. vol 101. issue 8-9. 2024-03-06. PMID:38445408. |
exceptionally, siadh can complicate esthesioneuroblastoma (enb) or olfactory neuroblastoma, a rare tumor of the nasal sinus cavities. |
2024-03-06 |
2024-03-08 |
Not clear |
| Bo Gao, Bin Han, Gengshi Gu, Haitao Wan. Intraoperative prevention of nasal mucosal injury and surgical field contamination during single-nostril transnasal endoscopic pituitary adenomas resection. Acta neurochirurgica. vol 166. issue 1. 2024-02-28. PMID:38416220. |
the common complications of transnasal endoscopic pituitary adenomas resection include nasal hemorrhage, olfactory disorder, nasal adhesion, and intracranial infection. |
2024-02-28 |
2024-03-01 |
Not clear |
| Yu-Qi Wu, Hui Li, Yi-Jie Fu, Tian-Min Zhu, Xin-Ru Gong, Zhou-Tong Han, Hong-Li Fa. [Systematic review and Meta-analysis of efficacy and safety of Bidouyan Oral Liquid in treatment of rhinosinusitis]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 49. issue 2. 2024-02-25. PMID:38403328. |
meta-analysis showed that bidouyan oral liquid + conventional treatment was superior to conventional treatment alone in increasing the total response rate(rr=1.19, 95%ci[1.15, 1.24], p<0.000 01) and decreasing the lund-kennedy scores(md=-1.94, 95%ci[-2.61,-1.26], p<0.000 01), lund-mackay scores(md=-2.14, 95%ci[-2.98,-1.31], p<0.000 01), and visual analogue scale(vas) scores(md_(total vas scores)=-1.28, 95%ci[-1.56,-1.01], p<0.000 01; md_(nasal congestion vas scores)=-0.58, 95%ci[-0.89,-0.27], p=0.000 2; md_(runny nose vas scores)=-0.61, 95%ci[-0.93,-0.29], p=0.000 2; md_(olfactory dysfunction vas scores)=-0.43, 95%ci[-0.52,-0.34], p<0.000 01; md_(head and facial pain vas scores)=-0.41, 95%ci[-0.57,-0.26], p<0.000 01). |
2024-02-25 |
2024-02-28 |
Not clear |
| Yu-Qi Wu, Hui Li, Yi-Jie Fu, Tian-Min Zhu, Xin-Ru Gong, Zhou-Tong Han, Hong-Li Fa. [Systematic review and Meta-analysis of efficacy and safety of Bidouyan Oral Liquid in treatment of rhinosinusitis]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 49. issue 2. 2024-02-25. PMID:38403328. |
bidouyan oral liquid was superior to conventional treatment in increasing total response rate(rr=1.25, 95%ci[1.18, 1.32], p<0.000 01), decreasing the lund-kennedy(p<0.01) and lund-mackay scores(p<0.05), alleviating major symptoms(p_(total vas scores)<0.01; p_(nasal congestion vas scores)<0.01; p_(runny nose vas scores)<0.01; p_(olfactory dysfunction vas scores)<0.05; p_(head and facial pain vas scores)<0.01), and decreasing adverse reactions(p=0.03). |
2024-02-25 |
2024-02-28 |
Not clear |
| Naomi Osakabe, Takafumi Shimizu, Yasuyuki Fujii, Taiki Fushimi, Vittorio Calabres. Sensory Nutrition and Bitterness and Astringency of Polyphenols. Biomolecules. vol 14. issue 2. 2024-02-24. PMID:38397471. |
recent studies have demonstrated that the interaction of dietary constituents with taste and olfactory receptors and nociceptors expressed in the oral cavity, nasal cavity and gastrointestinal tract regulate homeostasis through activation of the neuroendocrine system. |
2024-02-24 |
2024-02-26 |
Not clear |
| Fernando Lopez, Abbas Agaimy, Alessandro Franchi, Carlos Suárez, Vincent Vander Poorten, Antti A Mäkitie, Akihiro Homma, Avraham Eisbruch, Kerry D Olsen, Nabil F Saba, Sandra Nuyts, Carl Snyderman, Jonathan J Beitler, June Corry, Ehab Hanna, Henrik Hellquist, Alessandra Rinaldo, Alfio Ferlit. Update on olfactory neuroblastoma. Virchows Archiv : an international journal of pathology. 2024-02-22. PMID:38386106. |
olfactory neuroblastomas are uncommon malignancies that arise from olfactory receptor cells located high in the nasal cavity. |
2024-02-22 |
2024-02-24 |
Not clear |
| Yi Han, Lin Ai, Sha Sha, Jingwei Zhou, Hanyu Fu, Changcheng Sun, Ruiqi Liu, Anan Li, Jun-Li Cao, Ankang Hu, Hongxing Zhan. The functional role of the visual and olfactory modalities in the development of socially transferred mechanical hypersensitivity in male C57BL/6J mice. Physiology & behavior. 2024-02-20. PMID:38378074. |
methimazole-induced olfactory deprivation, a compound with reversible toxicity on the nasal olfactory epithelium, was sufficient to prevent the development of socially-transferred mechanical hypersensitivity. |
2024-02-20 |
2024-02-23 |
mouse |
| Yuta Iijima, Ryohei Miki, Nobumasa Takasugi, Masatake Fujimura, Takashi Uehar. Characterization of pathological changes in the olfactory system of mice exposed to methylmercury. Archives of toxicology. 2024-02-17. PMID:38367039. |
mice exposed to mehg displayed significant mercury accumulation in the olfactory pathway, including the nasal mucosa, olfactory bulb, and olfactory cortex. |
2024-02-17 |
2024-02-20 |
mouse |
| Junsheng Hong, Zhenlin Wang, Dawei W. Patterns of Olfactory Impairment Among Patients with Uncontrolled Chronic Rhinosinusitis. The Laryngoscope. 2024-02-16. PMID:38362947. |
self-reported olfactory dysfunction is an assessment component criterion for chronic rhinosinusitis (crs) disease control of the european position paper on rhinosinusitis and nasal polyps (epos). |
2024-02-16 |
2024-02-18 |
Not clear |
| Kara A Parikh, Sanjeet Rangarajan, L Madison Michae. Commentary: Superior Ethmoidal Approach to an Olfactory Groove Meningioma: Maximizing Preservation of Nasal Anatomy. Operative neurosurgery (Hagerstown, Md.). 2024-02-16. PMID:38363852. |
commentary: superior ethmoidal approach to an olfactory groove meningioma: maximizing preservation of nasal anatomy. |
2024-02-16 |
2024-02-19 |
Not clear |
| Berenice Stella Brabahar, Regi Kurien, Raga Panicker, Grace Rebekah, Lalee Varghes. Threshold and suprathreshold component analysis in olfactory dysfunction: a retrospective study. The Journal of laryngology and otology. 2024-02-12. PMID:38058015. |
to analyse variations in the n-butanol threshold and odour identification scores of the connecticut chemosensory clinical research centre test in various grades of olfactory dysfunction and in different nasal conditions leading to olfactory loss. |
2024-02-12 |
2024-02-14 |
Not clear |
| Muhammad Ali Shahbaz, Suvi Kuivanen, Laura Mussalo, Alexey M Afonin, Kajal Kumari, Donya Behzadpour, Juho Kalapudas, Anne M Koivisto, Elina Penttilä, Heikki Löppönen, Pasi Jalava, Olli Vapalahti, Giuseppe Balistreri, Riikka Lampinen, Katja M Kannine. Exposure to urban particulate matter alters responses of olfactory mucosal cells to SARS-CoV-2 infection. Environmental research. 2024-02-10. PMID:38341073. |
the olfactory mucosa (om), a tissue located at the rooftop of the nasal cavity, is directly exposed to inhaled air and in direct contact with the brain. |
2024-02-10 |
2024-02-14 |
human |
| Aida Maaz, Ian S Blagbrough, Paul A De Ban. A Cell-Based Nasal Model for Screening the Deposition, Biocompatibility, and Transport of Aerosolized PLGA Nanoparticles. Molecular pharmaceutics. 2024-02-09. PMID:38333983. |
the olfactory region of the nasal cavity directly links the brain to the external environment, presenting a potential direct route to the central nervous system (cns). |
2024-02-09 |
2024-02-11 |
human |
| Aida Maaz, Ian S Blagbrough, Paul A De Ban. A Cell-Based Nasal Model for Screening the Deposition, Biocompatibility, and Transport of Aerosolized PLGA Nanoparticles. Molecular pharmaceutics. 2024-02-09. PMID:38333983. |
however, targeting drugs to the olfactory region is challenging and relies on a combination of drug formulation, delivery device, and administration technique to navigate human nasal anatomy. |
2024-02-09 |
2024-02-11 |
human |
| Cécilia Neige, Laetitia Imbert, Maylis Dumas, Anna Athanassi, Marc Thévenet, Nathalie Mandairon, Jérôme Bruneli. Combining a Breath-Synchronized Olfactometer with Brain Simulation to Study the Impact of Odors on Corticospinal Excitability and Effective Connectivity. Journal of visualized experiments : JoVE. issue 203. 2024-02-05. PMID:38314795. |
to better understand the interactions between the olfactory and the motor systems and to overcome some of the previous methodological limitations, we developed a new method combining an olfactometer that synchronizes the random order presentation of odorants with different hedonic values and the tms (single- and dual-coil) triggering with nasal breathing phases. |
2024-02-05 |
2024-02-09 |
human |
| Saltanat Ualiyeva, Evan Lemire, Caitlin Wong, Alexander Perniss, Amelia A Boyd, Evelyn C Avilés, Dante G Minichetti, Alice Maxfield, Rachel Roditi, Ichiro Matsumoto, Xin Wang, Wenjiang Deng, Nora A Barrett, Kathleen M Buchheit, Tanya M Laidlaw, Joshua A Boyce, Lora G Bankova, Adam L Habe. A nasal cell atlas reveals heterogeneity of tuft cells and their role in directing olfactory stem cell proliferation. Science immunology. vol 9. issue 92. 2024-02-02. PMID:38306414. |
a nasal cell atlas reveals heterogeneity of tuft cells and their role in directing olfactory stem cell proliferation. |
2024-02-02 |
2024-02-05 |
mouse |
| Saltanat Ualiyeva, Evan Lemire, Caitlin Wong, Alexander Perniss, Amelia A Boyd, Evelyn C Avilés, Dante G Minichetti, Alice Maxfield, Rachel Roditi, Ichiro Matsumoto, Xin Wang, Wenjiang Deng, Nora A Barrett, Kathleen M Buchheit, Tanya M Laidlaw, Joshua A Boyce, Lora G Bankova, Adam L Habe. A nasal cell atlas reveals heterogeneity of tuft cells and their role in directing olfactory stem cell proliferation. Science immunology. vol 9. issue 92. 2024-02-02. PMID:38306414. |
the olfactory neuroepithelium serves as a sensory organ for odors and forms part of the nasal mucosal barrier. |
2024-02-02 |
2024-02-05 |
mouse |