| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Huaqing Zhang, Yun Chen, Miao Yu, Yilong Xi, Guochen Han, Yi Jin, Gang Wang, Xinzhu Sun, Jianping Zhou, Yang Din. Nasal delivery of polymeric nanoDisc mobilizes a synergy of central and peripheral amyloid-β clearance to treat Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. vol 120. issue 51. 2023-12-12. PMID:38085773. |
after intranasal administration and response to slightly acidic nasal microenvironment, polydisc depolymerizes into carrier-free hdl-disc with chitosan derivatives that adhere to the mucosal layer to reversibly open tight junctions, helping hdl-disc penetrate the olfactory pathway into brain. |
2023-12-12 |
2023-12-17 |
mouse |
| Xiao-Lin Zhong, Yan Huang, Yang Du, Li-Zheng He, Yue-Wen Chen, Yong Cheng, Hua Li. Unlocking the Therapeutic Potential of Exosomes Derived From Nasal Olfactory Mucosal Mesenchymal Stem Cells: Restoring Synaptic Plasticity, Neurogenesis, and Neuroinflammation in Schizophrenia. Schizophrenia bulletin. 2023-12-12. PMID:38086528. |
unlocking the therapeutic potential of exosomes derived from nasal olfactory mucosal mesenchymal stem cells: restoring synaptic plasticity, neurogenesis, and neuroinflammation in schizophrenia. |
2023-12-12 |
2023-12-17 |
Not clear |
| Xiao-Lin Zhong, Yan Huang, Yang Du, Li-Zheng He, Yue-Wen Chen, Yong Cheng, Hua Li. Unlocking the Therapeutic Potential of Exosomes Derived From Nasal Olfactory Mucosal Mesenchymal Stem Cells: Restoring Synaptic Plasticity, Neurogenesis, and Neuroinflammation in Schizophrenia. Schizophrenia bulletin. 2023-12-12. PMID:38086528. |
we hypothesized that intranasal administration of exosomes derived from nasal olfactory mucosal mesenchymal stem cells (om-mscs-exos) could alleviate scz-like behaviors in a murine model induced by methylazoxymethanol (mam). |
2023-12-12 |
2023-12-17 |
Not clear |
| Shizuko Murakami, Hiroko Ohki-Hamazaki, Yasuo Uchiyam. Somatostatin affects GnRH neuronal development and migration and stimulates olfactory-related fiber fasciculation. Developmental neurobiology. 2023-12-10. PMID:38072668. |
using in ovo electroporation of small interfering rna, we found that the suppression of sst mrna in the olfactory placode (op) of e3.5 chick embryos significantly reduced the number of gnrh and islet-1-immunoreactive neurons in the nasal region without affecting the entry of gnrh neurons into the fb at e5.5-6. |
2023-12-10 |
2023-12-17 |
chicken |
| Xueren Li, Yihuan Yan, Xiang Fang, Jiyuan T. Numerical studies of indoor particulate and gaseous micropollutant transport and its impact on human health in densely-occupied spaces. Environmental pollution (Barking, Essex : 1987). 2023-11-30. PMID:38036091. |
notably, the olfactory and sinus regions displayed heightened vulnerability to tvoc exposure, with a 62.5%-108% concentration increase compared to other nasal areas. |
2023-11-30 |
2023-12-10 |
human |
| Ya Zhang, Zhenzhen Hu, Yusheng Wang, Miao Lou, Ruiping Ma, Minjie Gong, Jingliang Dong, Guoxi Zheng, Botao Wan. Numerical investigation of nanoparticle deposition in the olfactory region among pediatric nasal airways with adenoid hypertrophy. Computers in biology and medicine. vol 167. 2023-11-25. PMID:37890422. |
numerical investigation of nanoparticle deposition in the olfactory region among pediatric nasal airways with adenoid hypertrophy. |
2023-11-25 |
2023-11-28 |
Not clear |
| Ya Zhang, Zhenzhen Hu, Yusheng Wang, Miao Lou, Ruiping Ma, Minjie Gong, Jingliang Dong, Guoxi Zheng, Botao Wan. Numerical investigation of nanoparticle deposition in the olfactory region among pediatric nasal airways with adenoid hypertrophy. Computers in biology and medicine. vol 167. 2023-11-25. PMID:37890422. |
to understand inhaled nanoparticle transport and deposition characteristics in pediatric nasal airways with adenoid hypertrophy (ah), with a specific emphasis on the olfactory region, virtual nanoparticle inhalation studies were conducted on anatomically accurate child nasal airway models. |
2023-11-25 |
2023-11-28 |
Not clear |
| Aida Pedram, Azadeh Torkzadeh, Roshanak Ghaffari, Seyed Sasan Aryanezha. Assessing Olfactory Fossa Depth and Its Relationship with the Variations in Adjacent Anatomical Structures by Using Cone Beam Computed Tomography (CBCT). Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India. vol 75. issue 4. 2023-11-18. PMID:37974708. |
correlation of olfactory fossa depth with the size of adjacent anatomical structures such as middle concha length, maximum orbital height and distance from ethmoid roof to nasal floor and ethmoid roof height to the palate in the anterior and posterior, length, and lateral angle of the lamella and cribriform plate distance. |
2023-11-18 |
2023-11-20 |
Not clear |
| A Raghvi, K Priya, S Rajasekaran, S Prabakaran, R B Namasivaya Navin, D Balaji, K Gowtham. Evaluating the Outcomes of Closed Reduction of Different Types of Nasal Bone Fractures. Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India. vol 75. issue 4. 2023-11-18. PMID:37974860. |
we could thus conclude from this study that early closed reduction of nasal bone fracture gave better results than a late closed reduction in terms of post operative deformity, arch irregularity, malalignment, bony irregularity, bony displacement and olfactory disturbances. |
2023-11-18 |
2023-11-20 |
human |
| Viktoria Sharova, Vasilina Ignatiuk, Marina Izvolskaia, Liudmila Zakharov. Disruption of Intranasal GnRH Neuronal Migration Route into the Brain Induced by Proinflammatory Cytokine IL-6: Ex Vivo and In Vivo Rodent Models. International journal of molecular sciences. vol 24. issue 21. 2023-11-14. PMID:37958965. |
the increased level of il-6 in mouse nasal explants suppressed peripherin-positive fiber outgrowth, while this led to an increase in the number of gnrh-neurons in the nose and olfactory bulbs and a decrease in their number in the fetal brain. |
2023-11-14 |
2023-11-20 |
mouse |
| Zhongliang Fu, Chen M. The impact of postoperative topical corticosteroid irrigation on short-term efficacy and olfactory function in patients with chronic rhinosinusitis with nasal polyps following endoscopic sinus surgery. Minerva medica. 2023-11-10. PMID:37947783. |
the impact of postoperative topical corticosteroid irrigation on short-term efficacy and olfactory function in patients with chronic rhinosinusitis with nasal polyps following endoscopic sinus surgery. |
2023-11-10 |
2023-11-20 |
Not clear |
| Cosimo Galletti, Martina Ragusa, Federico Sireci, Francesco Ciodaro, Maria Antonietta Barbieri, Giorgia Giunta, Egle Grigaliute, Angelo Immordino, Francesco Lorusso, Francesco Dispenza, Francesco Freni, Francesco Galletti, Salvatore Gallina, Igo La Mantia, Bruno Gallett. Dupilumab in chronic rhinosinusitis with nasal polyps: Real life data in a multicentric Sicilian experience. American journal of otolaryngology. vol 45. issue 1. 2023-11-10. PMID:37948824. |
this study aimed to evaluate the effectiveness and safety of dupilumab during the first year of treatment in a real-life setting, focusing on improvement in nasal polyp score (nps) as well as specific symptoms, quality of life and olfactory function. |
2023-11-10 |
2023-11-20 |
Not clear |
| Nandini Seshan, Simon Hanft, Gayotri Goswami, Arjun Sya. Primary Sellar Neuroblastoma Masquerading as a Pituitary Macroadenoma. JCEM case reports. vol 1. issue 4. 2023-11-01. PMID:37908997. |
olfactory neuroblastomas, or esthesioneuroblastomas, are rare and aggressive malignant tumors that typically arise from the olfactory neuroepithelium in the upper nasal cavity. |
2023-11-01 |
2023-11-08 |
Not clear |
| Johnny Sousa Ferreira, Daniel Pacheco Brusch. Tracking the Diversity and Chromosomal Distribution of the Olfactory Receptor Gene Repertoires of Three Anurans Species. Journal of molecular evolution. 2023-10-31. PMID:37906255. |
olfaction is a crucial capability for most vertebrates and is realized through olfactory receptors in the nasal cavity. |
2023-10-31 |
2023-11-08 |
xenopus_laevis |
| Fuka Takeuchi, Aki Sugano, Azusa Yoneshige, Man Hagiyama, Takao Inoue, Akihiro Wada, Yutaka Takaoka, Akihiko It. Potential Contribution of Cell Adhesion Molecule 1 to the Binding of SARS-CoV-2 Spike Protein to Mouse Nasal Mucosa. Cells, tissues, organs. 2023-10-30. PMID:37903481. |
since the nasal mucosa is lined by respiratory and olfactory epithelia, and both express an immunoglobulin superfamily member cell adhesion molecule 1 (cadm1), whether cadm1 would participate in the spike protein binding was examined. |
2023-10-30 |
2023-11-08 |
mouse |
| Carlo C Lazado, Marianne Iversen, Lill-Heidi Johansen, Hanne Brenne, Arvind Y M Sundaram, Elisabeth Yttebor. Nasal responses to elevated temperature and Francisella noatunensis infection in Atlantic cod (Gadus morhua). Genomics. 2023-10-28. PMID:37898334. |
in conclusion, the study reveals that elevated temperature could trigger responses in the olfactory organ of atlantic cod and shape the nasal response to f. noatunensis infection. |
2023-10-28 |
2023-11-08 |
Not clear |
| Aaqib Sohail, Jonathan Hacker, Tessa Ryan, Alanna McGill, Regan Bergmark, Neil Bhattacharyya, Stella E Lee, Alice Maxfield, Rachel Roditi, Amelie M Julé, Alec Griffith, James Lederer, Tanya M Laidlaw, Kathleen M Buchhei. Nasal polyp antibody secreting cells display proliferation signature in aspirin-exacerbated respiratory disease. The Journal of allergy and clinical immunology. 2023-10-28. PMID:37898408. |
chronic rhinosinusitis with nasal polyps (crswnp) causes nasal obstruction and olfactory dysfunction. |
2023-10-28 |
2023-11-08 |
Not clear |
| Kala Kumaresan, Sara Bengtsson, Saber Sami, Allan Clark, Thomas Hummel, James Boardman, Juliet High, Rashed Sobhan, Carl Philpot. A double-blinded randomised controlled trial of vitamin A drops to treat post-viral olfactory loss: study protocol for a proof-of-concept study for vitamin A nasal drops in post-viral olfactory loss (APOLLO). Pilot and feasibility studies. vol 9. issue 1. 2023-10-12. PMID:37828592. |
a double-blinded randomised controlled trial of vitamin a drops to treat post-viral olfactory loss: study protocol for a proof-of-concept study for vitamin a nasal drops in post-viral olfactory loss (apollo). |
2023-10-12 |
2023-10-15 |
Not clear |
| Huan Liu, Xin Cui, Zhi-Fei Wang, Qiang Zhang, Yuan-Yuan Li, Lian-Xin Wang, Jun-Yu Xi, Yan-Ming Xie, Li-Xun Li, Lei Zhan. [Clinical comprehensive evaluation of Xiangju Capsules in treatment of rhinosinusitis]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 48. issue 15. 2023-10-06. PMID:37802793. |
based on the available studies, the risk is controllable and the safety is grade a. meta-analysis showed that xiangju capsules + conventional western medicine could recover the lund-kennedy score, lund-mackay score, and ct score, relieve headache, nasal congestion, olfactory disturbance, and facial pain, with the effectiveness is grade b. |
2023-10-06 |
2023-10-15 |
human |
| Augustus Diaz, Francis De Castro, Venkat Reddy, Kel Anyanw. A 10-Year Retrospective Review of the Histology of Symptomatic and Asymptomatic Unilateral Nasal Polyps. Cureus. vol 15. issue 9. 2023-10-04. PMID:37790007. |
15 of these masses were found incidentally, with 14 being inflammatory, and one an olfactory neuroblastoma; therefore, 6.67% of our incidental unilateral nasal masses were found to be of neoplastic pathology. |
2023-10-04 |
2023-10-07 |
Not clear |