| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Namjil N Tsybikov, Elena V Egorova, Boris I Kuznik, Elena V Fefelova, Eli Mage. Neuron-specific enolase in nasal secretions as a novel biomarker of olfactory dysfunction in chronic rhinosinusitis. American journal of rhinology & allergy. vol 30. issue 1. 2016-12-13. PMID:26867533. |
during chronic inflammation and olfactory neuronal damage in crs, it is likely that neuron-specific enolase (nse) can leak into nasal secretions (ns) and serum. |
2016-12-13 |
2023-08-13 |
Not clear |
| Shital Lungare, James Bowen, Raj Badha. Development and Evaluation of a Novel Intranasal Spray for the Delivery of Amantadine. Journal of pharmaceutical sciences. vol 105. issue 3. 2016-12-13. PMID:26886345. |
using a human nasal cast model, deposition into the olfactory regions (potential nose-to-brain) was demonstrated on nozzle insertion (5 mm), whereas tilting of the head forward (15°) resulted in greater deposition in the bulk of the nasal cavity. |
2016-12-13 |
2023-08-13 |
human |
| Eri Mori, Christos Merkonidis, Mandy Cuevas, Volker Gudziol, Yoshinori Matsuwaki, Thomas Humme. The administration of nasal drops in the "Kaiteki" position allows for delivery of the drug to the olfactory cleft: a pilot study in healthy subjects. European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery. vol 273. issue 4. 2016-10-27. PMID:26141752. |
the administration of nasal drops in the "kaiteki" position allows for delivery of the drug to the olfactory cleft: a pilot study in healthy subjects. |
2016-10-27 |
2023-08-13 |
human |
| Eri Mori, Christos Merkonidis, Mandy Cuevas, Volker Gudziol, Yoshinori Matsuwaki, Thomas Humme. The administration of nasal drops in the "Kaiteki" position allows for delivery of the drug to the olfactory cleft: a pilot study in healthy subjects. European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery. vol 273. issue 4. 2016-10-27. PMID:26141752. |
with regard to the main criterion of this study, using the "kaiteki" position, nasal drops reached the olfactory cleft in 96 % of the decongested cases and 75 % of the cases who had not been decongested. |
2016-10-27 |
2023-08-13 |
human |
| Mawuli P K Agbesi, Sara Naylor, Elizabeth Perkins, Heather S Borsuk, Dan Sykes, James S Maclaine, Zhijin Wang, Jonathan P L Co. Complex flow in the nasal region of guitarfishes. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology. vol 193. 2016-10-24. PMID:26780177. |
we set out to determine the mechanisms for moving water through the olfactory organ of guitarfishes (rhinobatidae, chondrichthyes) with open nasal cavities. |
2016-10-24 |
2023-08-13 |
Not clear |
| Mawuli P K Agbesi, Sara Naylor, Elizabeth Perkins, Heather S Borsuk, Dan Sykes, James S Maclaine, Zhijin Wang, Jonathan P L Co. Complex flow in the nasal region of guitarfishes. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology. vol 193. 2016-10-24. PMID:26780177. |
in the first mechanism, which we identified by observing dye movement in the nasal region of a life-sized physical model of the head of rhinobatos lentiginosus mounted in a flume, olfactory flow is generated by the guitarfish's motion relative to water, e.g. |
2016-10-24 |
2023-08-13 |
Not clear |
| Mawuli P K Agbesi, Sara Naylor, Elizabeth Perkins, Heather S Borsuk, Dan Sykes, James S Maclaine, Zhijin Wang, Jonathan P L Co. Complex flow in the nasal region of guitarfishes. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology. vol 193. 2016-10-24. PMID:26780177. |
we suggest that the pressure difference responsible for motion-driven olfactory flow is caused by the guitarfish's nasal flaps, which create a region of high pressure at the incurrent nostril, and a region of low pressure in and behind the nasal cavity. |
2016-10-24 |
2023-08-13 |
Not clear |
| Mawuli P K Agbesi, Sara Naylor, Elizabeth Perkins, Heather S Borsuk, Dan Sykes, James S Maclaine, Zhijin Wang, Jonathan P L Co. Complex flow in the nasal region of guitarfishes. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology. vol 193. 2016-10-24. PMID:26780177. |
in the second mechanism, which we identified by observing dye movement in the nasal regions of living specimens of glaucostegus typus, the guitarfish's respiratory pump draws flow through the olfactory organ in a rhythmic (0.5-2 hz), but continuous, fashion. |
2016-10-24 |
2023-08-13 |
Not clear |
| Mawuli P K Agbesi, Sara Naylor, Elizabeth Perkins, Heather S Borsuk, Dan Sykes, James S Maclaine, Zhijin Wang, Jonathan P L Co. Complex flow in the nasal region of guitarfishes. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology. vol 193. 2016-10-24. PMID:26780177. |
based on our results, we propose a model for olfactory flow in guitarfishes with open nasal cavities, and suggest other neoselachians which this model might apply to. |
2016-10-24 |
2023-08-13 |
Not clear |
| Erin T Larragoite, Luca Tacchi, Scott E LaPatra, Irene Salina. An attenuated virus vaccine appears safe to the central nervous system of rainbow trout (Oncorhynchus mykiss) after intranasal delivery. Fish & shellfish immunology. vol 49. 2016-10-21. PMID:26772477. |
nasal vaccines are very effective but the olfactory organ provides direct access of antigens to the brain. |
2016-10-21 |
2023-08-13 |
Not clear |
| Hitoshi Sasajima, Sadaharu Miyazono, Tomohiro Noguchi, Makoto Kashiwayanag. Intranasal administration of rotenone in mice attenuated olfactory functions through the lesion of dopaminergic neurons in the olfactory bulb. Neurotoxicology. vol 51. 2016-10-12. PMID:26493152. |
it was reported that chemicals in the nasal cavity directly reach the brain through the connection between olfactory neurons and the olfactory bulb (ob). |
2016-10-12 |
2023-08-13 |
mouse |
| Hitoshi Sasajima, Sadaharu Miyazono, Tomohiro Noguchi, Makoto Kashiwayanag. Intranasal administration of rotenone in mice attenuated olfactory functions through the lesion of dopaminergic neurons in the olfactory bulb. Neurotoxicology. vol 51. 2016-10-12. PMID:26493152. |
in this 'olfactory transport,' xenobiotics absorbed at the nasal mucosa reach the brain by bypassing some physical barriers and defenses, and thus olfactory transport is suspected to be a vulnerable mechanism of the brain against invasion threats of environmental chemicals. |
2016-10-12 |
2023-08-13 |
mouse |
| Kaiming Su, Weitian Zhang, Haibo Shi, Shankai Yi. Pedunculated cavernous hemangioma originating in the olfactory cleft. Ear, nose, & throat journal. vol 93. issue 9. 2016-10-05. PMID:25255356. |
we report the case of a 77-year-old man who presented with severe epistaxis, nasal congestion, and olfactory dysfunction. |
2016-10-05 |
2023-08-13 |
Not clear |
| J Enrique Cometto-Muñiz, Michael H Abraha. Dose-Response Functions for the Olfactory, Nasal Trigeminal, and Ocular Trigeminal Detectability of Airborne Chemicals by Humans. Chemical senses. vol 41. issue 1. 2016-09-29. PMID:26476441. |
dose-response functions for the olfactory, nasal trigeminal, and ocular trigeminal detectability of airborne chemicals by humans. |
2016-09-29 |
2023-08-13 |
Not clear |
| Wen Jiang, Jieqiong Liu, Patrick J Gullane, Fred Gentili, Robert E Wharen, Betty Y S Kim, Franco DeMont. Non-contiguous meningeal metastases of olfactory neuroblastoma. Journal of neuro-oncology. vol 126. issue 1. 2016-09-28. PMID:26376653. |
olfactory neuroblastoma (onb) is a malignant neoplasm centered along the roof of the nasal cavity near the cribriform plate. |
2016-09-28 |
2023-08-13 |
Not clear |
| Varsha Dhamankar, Mahfoud Assem, Maureen D Donova. Gene expression and immunochemical localization of major cytochrome P450 drug-metabolizing enzymes in bovine nasal olfactory and respiratory mucosa. Inhalation toxicology. vol 27. issue 14. 2016-09-27. PMID:26572092. |
gene expression and immunochemical localization of major cytochrome p450 drug-metabolizing enzymes in bovine nasal olfactory and respiratory mucosa. |
2016-09-27 |
2023-08-13 |
cattle |
| Varsha Dhamankar, Mahfoud Assem, Maureen D Donova. Gene expression and immunochemical localization of major cytochrome P450 drug-metabolizing enzymes in bovine nasal olfactory and respiratory mucosa. Inhalation toxicology. vol 27. issue 14. 2016-09-27. PMID:26572092. |
an extensive knowledge of the oxidative and conjugative metabolizing capacity of the cattle (bos taurus) olfactory and respiratory mucosa can aid in efficient use of these tissues for pre-clinical investigations of the biotransformation and toxicity of therapeutic agents following nasal administration or inhalation. |
2016-09-27 |
2023-08-13 |
cattle |
| Varsha Dhamankar, Mahfoud Assem, Maureen D Donova. Gene expression and immunochemical localization of major cytochrome P450 drug-metabolizing enzymes in bovine nasal olfactory and respiratory mucosa. Inhalation toxicology. vol 27. issue 14. 2016-09-27. PMID:26572092. |
the results demonstrate that bovine nasal olfactory and respiratory mucosal and liver tissues express similar populations, families, and distributions of cyp enzymes, as has been previously reported with other species, including humans. |
2016-09-27 |
2023-08-13 |
cattle |
| Jiaqiang Xu, Gao Li, Zhuoyi Wang, Luqin Si, Sijie He, Jialing Cai, Jiangeng Huang, Maureen D Donova. The role of L-type amino acid transporters in the uptake of glyphosate across mammalian epithelial tissues. Chemosphere. vol 145. 2016-09-27. PMID:26701683. |
to investigate the mechanisms of glyphosate absorption across epithelial tissues, the permeation of glyphosate across caco-2 cells, a gastrointestinal epithelium model, was compared with permeation across nasal respiratory and olfactory tissues excised from cows. |
2016-09-27 |
2023-08-13 |
Not clear |
| K Zycinska, M Straburzynski, A Nitsch-Osuch, R Krupa, M Hadzik-Błaszczyk, M Cieplak, K Wardy. Prevalence of Olfactory Impairment in Granulomatosis with Polyangiitis. Advances in experimental medicine and biology. vol 878. 2016-09-23. PMID:26269029. |
active nasal and paranasal sinus inflammation in gpa leads to olfactory dysfunction, the patients are often unaware of. |
2016-09-23 |
2023-08-13 |
human |