| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Lucas Engelhardt, Martina Röhm, Chrystelle Mavoungou, Katharina Schindowski, Annette Schafmeister, Ulrich Simo. First Steps to Develop and Validate a CFPD Model in Order to Support the Design of Nose-to-Brain Delivered Biopharmaceuticals. Pharmaceutical research. vol 33. issue 6. 2017-03-09. PMID:26887679. |
aerosol particle deposition in the human nasal cavity is of high interest in particular for intranasal central nervous system (cns) drug delivery via the olfactory cleft. |
2017-03-09 |
2023-08-13 |
human |
| Lucas Engelhardt, Martina Röhm, Chrystelle Mavoungou, Katharina Schindowski, Annette Schafmeister, Ulrich Simo. First Steps to Develop and Validate a CFPD Model in Order to Support the Design of Nose-to-Brain Delivered Biopharmaceuticals. Pharmaceutical research. vol 33. issue 6. 2017-03-09. PMID:26887679. |
the objective of this study was the development and comparison of a numerical and experimental model to investigate various parameters for olfactory particle deposition within the complex anatomical nasal geometry. |
2017-03-09 |
2023-08-13 |
human |
| Jinxiang Xi, Jiayao Eddie Yuan, Yu Zhang, Dannielle Nevorski, Zhaoxuan Wang, Yue Zho. Visualization and Quantification of Nasal and Olfactory Deposition in a Sectional Adult Nasal Airway Cast. Pharmaceutical research. vol 33. issue 6. 2017-03-09. PMID:26943943. |
visualization and quantification of nasal and olfactory deposition in a sectional adult nasal airway cast. |
2017-03-09 |
2023-08-13 |
Not clear |
| Jinxiang Xi, Jiayao Eddie Yuan, Yu Zhang, Dannielle Nevorski, Zhaoxuan Wang, Yue Zho. Visualization and Quantification of Nasal and Olfactory Deposition in a Sectional Adult Nasal Airway Cast. Pharmaceutical research. vol 33. issue 6. 2017-03-09. PMID:26943943. |
to compare drug deposition in the nose and olfactory region with different nasal devices and administration techniques. |
2017-03-09 |
2023-08-13 |
Not clear |
| Anke Schlüter, Yahya Ahmadipour, Trutz Vogelsang, Ilonka Kreitschmann-Andermahr, Bernadette Kleist, Patrick Weller, Laura Holtmann, Stefan Mattheis, Stephan Lang, Christoph Bergmann, Oliver Muelle. Evaluation of the application of rhino-septal splints in endoscopic transsphenoidal skull base surgery. European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery. vol 273. issue 12. 2017-03-09. PMID:27363406. |
a standardized postsurgical follow-up investigation with endoscopic nasal examination, rhinomanometry and olfactory testing was performed on average 2 months postoperatively. |
2017-03-09 |
2023-08-13 |
Not clear |
| Andrzej Skorek, Dmitry Tretiakow, Tomasz Szmuda, Tomasz Przewozn. Is the Keros classification alone enough to identify patients with the 'dangerous ethmoid'? An anatomical study. Acta oto-laryngologica. vol 137. issue 2. 2017-03-06. PMID:27608833. |
parallel to keros type iii, the proposed determining factors include: olfactory fossa width >6 mm, its distance to the medial nasal concha (turbinate) <20 mm and to the orbit interval of <10 mm. |
2017-03-06 |
2023-08-13 |
Not clear |
| Jinxiang Xi, Jiayao Eddie Yuan, Mohammad Alshaiba, Dongxue Cheng, Zachary Firlit, Aaron Johnson, Alex Nolan, Wei-Chung S. Design and Testing of Electric-Guided Delivery of Charged Particles to the Olfactory Region: Experimental and Numerical Studies. Current drug delivery. vol 13. issue 2. 2017-02-17. PMID:26362143. |
however, clinical applications of the direct nose-to-brain delivery are rare because of the extremely low olfactory doses using conventional nasal devices. |
2017-02-17 |
2023-08-13 |
human |
| Jinxiang Xi, Jiayao Eddie Yuan, Mohammad Alshaiba, Dongxue Cheng, Zachary Firlit, Aaron Johnson, Alex Nolan, Wei-Chung S. Design and Testing of Electric-Guided Delivery of Charged Particles to the Olfactory Region: Experimental and Numerical Studies. Current drug delivery. vol 13. issue 2. 2017-02-17. PMID:26362143. |
in this study, the feasibility of electric-guided delivery to the olfactory region was tested in an anatomically accurate nasal airway model both experimentally and numerically. |
2017-02-17 |
2023-08-13 |
human |
| Jinxiang Xi, Jiayao Eddie Yuan, Mohammad Alshaiba, Dongxue Cheng, Zachary Firlit, Aaron Johnson, Alex Nolan, Wei-Chung S. Design and Testing of Electric-Guided Delivery of Charged Particles to the Olfactory Region: Experimental and Numerical Studies. Current drug delivery. vol 13. issue 2. 2017-02-17. PMID:26362143. |
compared to conventional nasal devices, electric-guidance of charged particles noticeably reduced particle losses in the anterior nose and increased depositions in the olfactory region. |
2017-02-17 |
2023-08-13 |
human |
| Adem Kilicaslan, Gul Ozbilen Acar, Muhammet Tekin, Osman Ilkay Ozdama. Assessment the long-term effects of septoplasty surgery on olfactory function. Acta oto-laryngologica. vol 136. issue 10. 2017-02-16. PMID:27228388. |
this research aimed to evaluate pre-operatively and post-operatively the olfactory function of patients who had undergone surgery in our clinic for chronic nasal blockage via the connecticut chemosensory clinical research center (cccrc) smell test. |
2017-02-16 |
2023-08-13 |
Not clear |
| Marcella Mauro, Matteo Crosera, Massimo Bovenzi, Gianpiero Adami, Francesca Larese Filo. Pilot study on in vitro silver nanoparticles permeation through meningeal membrane. Colloids and surfaces. B, Biointerfaces. vol 146. 2017-02-10. PMID:27344269. |
the olfactory bundles are surrounded by meningeal sheets in their path from the nasal mucosa to the olfactory bulb. |
2017-02-10 |
2023-08-13 |
Not clear |
| Kristine A Smith, Luke Rudmi. Delivery of Topical Therapies. Advances in oto-rhino-laryngology. vol 79. 2017-02-07. PMID:27466853. |
low-volume nasal sprays and drops provide reliable delivery to the nasal cavity and a degree of penetration into the middle meatus and olfactory cleft; however, they do not reliably penetrate the paranasal sinuses. |
2017-02-07 |
2023-08-13 |
Not clear |
| Eugenio Pozzati, Matteo Martinoni, Gianluca Marucci, Antonella Bacc. Olfactory neuroblastoma and olfactory ventricle. A case report. The neuroradiology journal. vol 27. issue 4. 2017-02-06. PMID:25196619. |
a case of dumbbell nasal and intracerebral olfactory neuroblastoma (onb) related to possible seeding through an "olfactory ventricle" in the olfactory bulb and nerve is reported. |
2017-02-06 |
2023-08-13 |
Not clear |
| Lizhi Wang, Yan Ding, Lai Wei, Dewei Zhao, Ruoyu Wang, Yuewei Zhang, Xuesong Gu, Zhiqiang Wan. Recurrent Olfactory Neuroblastoma Treated With Cetuximab and Sunitinib: A Case Report. Medicine. vol 95. issue 18. 2017-02-01. PMID:27149458. |
olfactory neuroblastoma (onb) is a rare cancer originating in the olfactory epithelium of the nasal vault. |
2017-02-01 |
2023-08-13 |
Not clear |
| Norman C Charles, Carisa K Petris, Eleanore T Ki. Aggressive esthesioneuroblastoma with divergent differentiation: A taxonomic dilemma. Orbit (Amsterdam, Netherlands). vol 35. issue 6. 2017-01-31. PMID:27715372. |
the authors describe an esthesioneuroblastoma (olfactory neuroblastoma) that occurred within the nasal cavity and brain in a 31-year-old man. |
2017-01-31 |
2023-08-13 |
Not clear |
| Douglas M Durrant, Soumitra Ghosh, Robyn S Klei. The Olfactory Bulb: An Immunosensory Effector Organ during Neurotropic Viral Infections. ACS chemical neuroscience. vol 7. issue 4. 2017-01-06. PMID:27058872. |
this hypothesis was based on experiments in which nasophayngeal infection with poliovirus in monkeys was prevented from spreading to their cns via transection of olfactory tracts between the olfactory neuroepithelium (one) of the nasal cavity and the olfactory bulb (ob). |
2017-01-06 |
2023-08-13 |
monkey |
| Helen E Farrell, Clara Lawler, Cindy S E Tan, Kate MacDonald, Kimberley Bruce, Michael Mach, Nick Davis-Poynter, Philip G Stevenso. Murine Cytomegalovirus Exploits Olfaction To Enter New Hosts. mBio. vol 7. issue 2. 2016-12-23. PMID:27118588. |
the viral m131/m129 chemokine homolog, which influences tropism, promoted salivary gland colonization after nasal entry but was not required for entry per se the capacity of mcmv to transmit via olfaction, together with previous demonstrations of experimental olfactory infection by murid herpesvirus 4 (muhv-4) and herpes simplex virus 1 (hsv-1), suggest that this is a common, conserved route of mammalian herpesvirus entry. |
2016-12-23 |
2023-08-13 |
Not clear |
| Daniel H Coelho, Richard M Costanz. Posttraumatic olfactory dysfunction. Auris, nasus, larynx. vol 43. issue 2. 2016-12-19. PMID:26441369. |
impairment of smell may occur following injury to any portion of the olfactory tract, from nasal cavity to brain. |
2016-12-19 |
2023-08-13 |
Not clear |
| Shoko Nakamuta, Makoto Yokosuka, Kazumi Taniguchi, Yoshio Yamamoto, Nobuaki Nakamut. Immunohistochemical analysis for G protein in the olfactory organs of soft-shelled turtle, Pelodiscus sinensis. The Journal of veterinary medical science. vol 78. issue 2. 2016-12-13. PMID:26440778. |
in turtles, the epithelia lining the upper and lower chambers of the nasal cavity project axons to the ventral and dorsal parts of the olfactory bulbs, respectively. |
2016-12-13 |
2023-08-13 |
Not clear |
| Namjil N Tsybikov, Elena V Egorova, Boris I Kuznik, Elena V Fefelova, Eli Mage. Neuron-specific enolase in nasal secretions as a novel biomarker of olfactory dysfunction in chronic rhinosinusitis. American journal of rhinology & allergy. vol 30. issue 1. 2016-12-13. PMID:26867533. |
neuron-specific enolase in nasal secretions as a novel biomarker of olfactory dysfunction in chronic rhinosinusitis. |
2016-12-13 |
2023-08-13 |
Not clear |