| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Carmen Entrala-Bernal, Cristina Montes-Castillo, Maria Jesus Alvarez-Cubero, Carmen Gutiérrez-Alcántara, Francisco Fernandez-Rosado, Esther Martinez-Espίn, Carolina Sánchez-Malo, Piedad Santiago-Fernánde. Genetic diagnosis of idiopathic hypogonadotrophic hypogonadism: a new point mutation in the KAL2 gene. Hormones (Athens, Greece). vol 13. issue 2. 2014-12-16. PMID:24776628. |
kallmann syndrome (ks) is a genetic disease of embryonic development which is characterized by the association of hypogonadotropic hypogonadism (hh) due to a deficit of the gonadotropin-releasing hormone (gnrh) and a hypo/anosmia (including a hypoplasia of the nasal sulcus and agenesis of the olfactory bulbs). |
2014-12-16 |
2023-08-13 |
Not clear |
| Dalia Ibrahim, Nobuaki Nakamuta, Kazumi Taniguchi, Yoshio Yamamoto, Kazuyuki Taniguch. Histological and lectin histochemical studies on the olfactory and respiratory mucosae of the sheep. The Journal of veterinary medical science. vol 76. issue 3. 2014-12-08. PMID:24200894. |
these findings indicate that the glycohistochemical characteristics of the free borders of both olfactory and respiratory epithelia are similar to each other, suggesting that secretions from the bowman's glands and those of the goblet cells and mucous nasal glands are partially exchanged between the surface of two epithelia to contribute the functions of the respiratory epithelium and the olfactory receptor cells, respectively. |
2014-12-08 |
2023-08-12 |
Not clear |
| Birgit Risberg-Berlin, Therese R Karlsson, Lisa Tuomi, Caterina Finizi. Effectiveness of olfactory rehabilitation according to a structured protocol with potential of regaining pre-operative levels in laryngectomy patients using nasal airflow-inducing manoeuvre. European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery. vol 271. issue 5. 2014-12-01. PMID:24077871. |
effectiveness of olfactory rehabilitation according to a structured protocol with potential of regaining pre-operative levels in laryngectomy patients using nasal airflow-inducing manoeuvre. |
2014-12-01 |
2023-08-12 |
Not clear |
| Jennifer Germano, Vanessa E Van Zerr, Todd C Esque, Ken E Nussear, Nadine Lambersk. Impacts of upper respiratory tract disease on olfactory behavior of the Mojave desert tortoise. Journal of wildlife diseases. vol 50. issue 2. 2014-12-01. PMID:24506425. |
this nasal congestion may result in a loss of the olfactory sense. |
2014-12-01 |
2023-08-12 |
Not clear |
| Jennifer Germano, Vanessa E Van Zerr, Todd C Esque, Ken E Nussear, Nadine Lambersk. Impacts of upper respiratory tract disease on olfactory behavior of the Mojave desert tortoise. Journal of wildlife diseases. vol 50. issue 2. 2014-12-01. PMID:24506425. |
to determine more specifically the impact nasal discharge might have on free-ranging tortoises (gopherus agassizii), we compared the responses of tortoises with and without nasal discharge and both positive and negative for m. agassizii antibodies to a visually hidden olfactory food stimulus and an empty control. |
2014-12-01 |
2023-08-12 |
Not clear |
| Luca Casettari, Lisbeth Illu. Chitosan in nasal delivery systems for therapeutic drugs. Journal of controlled release : official journal of the Controlled Release Society. vol 190. 2014-11-24. PMID:24818769. |
furthermore, the review also evaluates the use of chitosan formulations for the improvement of transport of drugs directly from the nasal cavity to the brain, based on its mucoadhesive characteristics and its ability to open tight junctions in the olfactory and respiratory epithelia. |
2014-11-24 |
2023-08-13 |
Not clear |
| Parvathi Devi, Radhika Bhavle, Avanti Aggarwal, Cherry Wali. Esthesioneuroblastoma presenting as tooth pain. Journal of oral and maxillofacial pathology : JOMFP. vol 18. issue Suppl 1. 2014-11-03. PMID:25364164. |
esthesioneuroblastoma, also called olfactory neuroblastoma, is a rare malignant tumor originating in the olfactory epithelium in the upper nasal cavity with intracranial extension and may also be associated with secondary sinus diseases. |
2014-11-03 |
2023-08-13 |
Not clear |
| Deepti Mittal, Asgar Ali, Shadab Md, Sanjula Baboota, Jasjeet K Sahni, Javed Al. Insights into direct nose to brain delivery: current status and future perspective. Drug delivery. vol 21. issue 2. 2014-10-31. PMID:24102636. |
this route involves the olfactory or trigeminal nerve systems which initiate in the brain and terminate in the nasal cavity at the olfactory neuroepithelium or respiratory epithelium. |
2014-10-31 |
2023-08-12 |
Not clear |
| Michael Katotomichelakis, Efthimios Simopoulos, Gregory Tripsianis, Dimitrios Balatsouras, Gerasimos Danielides, Christos Kourousis, Miltos Livaditis, Vassilios Danielide. Predictors of quality of life outcomes in chronic rhinosinusitis after sinus surgery. European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery. vol 271. issue 4. 2014-10-29. PMID:23842603. |
although olfactory dysfunction, nasal polyps, female gender, high socio-economic status and non-smoking habits were significantly associated with better qol results, multivariate logistic regression analysis revealed that only olfactory dysfunction and nasal polyps were independent predictors significantly associated with higher likelihood of clinically significant improvement in all qol questionnaire results. |
2014-10-29 |
2023-08-12 |
human |
| Michael Katotomichelakis, Efthimios Simopoulos, Gregory Tripsianis, Dimitrios Balatsouras, Gerasimos Danielides, Christos Kourousis, Miltos Livaditis, Vassilios Danielide. Predictors of quality of life outcomes in chronic rhinosinusitis after sinus surgery. European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery. vol 271. issue 4. 2014-10-29. PMID:23842603. |
olfactory dysfunction and nasal polyps were independent pre-operative predictors for surgical outcomes with regard to qol results. |
2014-10-29 |
2023-08-12 |
human |
| Cécile D Cros, Istvan Toth, Joanne T Blanchfiel. Delivery of a lactose derivative of endomorphin 1 to the brain via the olfactory epithelial pathway. Bioorganic & medicinal chemistry letters. vol 24. issue 5. 2014-10-28. PMID:24508131. |
these results indicate that the peptide is absorbed into the brain via the olfactory epithelial pathway suggesting nasal delivery may be a viable alternative route of delivery in clinical applications. |
2014-10-28 |
2023-08-12 |
rat |
| James A St John, Jenny A K Ekberg, Samantha J Dando, Adrian C B Meedeniya, Rachel E Horton, Michael Batzloff, Suzzanne J Owen, Stephanie Holt, Ian R Peak, Glen C Ulett, Alan Mackay-Sim, Ifor R Beacha. Burkholderia pseudomallei penetrates the brain via destruction of the olfactory and trigeminal nerves: implications for the pathogenesis of neurological melioidosis. mBio. vol 5. issue 2. 2014-10-27. PMID:24736221. |
we have now investigated in detail the mechanism by which the bacteria penetrate the olfactory and trigeminal nerves within the nasal cavity and infect the brain. |
2014-10-27 |
2023-08-13 |
mouse |
| James A St John, Jenny A K Ekberg, Samantha J Dando, Adrian C B Meedeniya, Rachel E Horton, Michael Batzloff, Suzzanne J Owen, Stephanie Holt, Ian R Peak, Glen C Ulett, Alan Mackay-Sim, Ifor R Beacha. Burkholderia pseudomallei penetrates the brain via destruction of the olfactory and trigeminal nerves: implications for the pathogenesis of neurological melioidosis. mBio. vol 5. issue 2. 2014-10-27. PMID:24736221. |
using immunohistochemistry, we demonstrated that b. pseudomallei migrated through the cribriform plate via the olfactory nerves to enter the outer layer of the olfactory bulb in the brain within 24 h. we also found that the bacteria colonized the thin respiratory epithelium in the nasal cavity and then rapidly migrated along the underlying trigeminal nerve to penetrate the cranial cavity. |
2014-10-27 |
2023-08-13 |
mouse |
| James A St John, Jenny A K Ekberg, Samantha J Dando, Adrian C B Meedeniya, Rachel E Horton, Michael Batzloff, Suzzanne J Owen, Stephanie Holt, Ian R Peak, Glen C Ulett, Alan Mackay-Sim, Ifor R Beacha. Burkholderia pseudomallei penetrates the brain via destruction of the olfactory and trigeminal nerves: implications for the pathogenesis of neurological melioidosis. mBio. vol 5. issue 2. 2014-10-27. PMID:24736221. |
by generating a mutant strain of b. pseudomallei which is unable to survive in the blood, we show that the bacteria rapidly penetrate the cranial cavity using the olfactory (smell) nerve and the trigeminal (sensory) nerve that line the nasal cavity. |
2014-10-27 |
2023-08-13 |
mouse |
| S Squillac. Olfactory neuroblastoma with focal ganglioneuroblastic differentiation: a case report with literature review. Pathologica. vol 106. issue 2. 2014-10-24. PMID:25291869. |
olfactory neuroblastoma (onb) is a rare malignant neuroectodermal tumour, with clearly defined histologic and immunohistochemical features, that typically arises in the superior nasal cavity. |
2014-10-24 |
2023-08-13 |
Not clear |
| Bayram Veyseller, Remzi Doğan, Berke Ozücer, Fadlullah Aksoy, Ayşenur Meriç, Ozlem Su, Orhan Oztura. Olfactory function and nasal manifestations of Behçet's disease. Auris, nasus, larynx. vol 41. issue 2. 2014-10-22. PMID:24183397. |
olfactory function and nasal manifestations of behçet's disease. |
2014-10-22 |
2023-08-12 |
Not clear |
| Bayram Veyseller, Remzi Doğan, Berke Ozücer, Fadlullah Aksoy, Ayşenur Meriç, Ozlem Su, Orhan Oztura. Olfactory function and nasal manifestations of Behçet's disease. Auris, nasus, larynx. vol 41. issue 2. 2014-10-22. PMID:24183397. |
to investigate the effect of behçet's disease on olfactory function, the nasal mucosa, and nasal symptoms. |
2014-10-22 |
2023-08-12 |
Not clear |
| Arthur W Barrios, Pablo Sánchez-Quinteiro, Ignacio Salaza. Dog and mouse: toward a balanced view of the mammalian olfactory system. Frontiers in neuroanatomy. vol 8. 2014-10-13. PMID:25309347. |
although the most intensively studied mammalian olfactory system is that of the mouse, in which olfactory chemical cues of one kind or another are detected in four different nasal areas [the main olfactory epithelium (moe), the septal organ (so), grüneberg's ganglion, and the sensory epithelium of the vomeronasal organ (vno)], the extraordinarily sensitive olfactory system of the dog is also an important model that is increasingly used, for example in genomic studies of species evolution. |
2014-10-13 |
2023-08-13 |
mouse |
| Eric M Bershad, Mian Z Urfy, Eusebia Calvillo, Rosa Tang, Christian Cajavilca, Andrew G Lee, Chethan P Venkatasubba Rao, Jose I Suarez, Denise Che. Marked olfactory impairment in idiopathic intracranial hypertension. Journal of neurology, neurosurgery, and psychiatry. vol 85. issue 9. 2014-10-02. PMID:24474821. |
some also present with nasal congestion and subjective olfactory impairment. |
2014-10-02 |
2023-08-12 |
Not clear |
| M Scheibe, S Schulze, C A Mueller, B Schuster, Thomas Humme. Intranasal trigeminal sensitivity: measurements before and after nasal surgery. European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery. vol 271. issue 1. 2014-09-16. PMID:23568039. |
nasal surgeries constitute an extensive manipulation of the nasal mucosa and therefore of structures related to trigeminal and olfactory sensitivity. |
2014-09-16 |
2023-08-12 |
human |