Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
ZhiWei Cao, ZhaoWei Gu, Jing Yang, MingZhu Ji. Respiratory epithelial adenomatoid hamartoma of bilateral olfactory clefts associated with nasal polyposis: three cases report and literature review. Auris, nasus, larynx. vol 37. issue 3. 2010-06-24. PMID:19942387. |
our cases were all localized in bilateral olfactory clefts which is very rare since the most common site reported in the past in nasal cavity is the posterior nasal septum and unilateral. |
2010-06-24 |
2023-08-12 |
Not clear |
H K Faber, L P Gebhard. LOCALIZATIONS OF THE VIRUS OF POLIOMYELITIS IN THE CENTRAL NERVOUS SYSTEM DURING THE PREPARALYTIC PERIOD, AFTER INTRANASAL INSTILLATION. The Journal of experimental medicine. vol 57. issue 6. 2010-06-23. PMID:19870171. |
it apparently reaches this structure through the axons of the olfactory nerves after primarily infecting the olfactory cells of the nasal mucosa. |
2010-06-23 |
2023-08-12 |
Not clear |
L T Webster, A D Clo. THE LIMITED NEUROTROPIC CHARACTER OF THE ENCEPHALITIS VIRUS (ST. LOUIS TYPE) IN SUSCEPTIBLE MICE. The Journal of experimental medicine. vol 63. issue 3. 2010-06-23. PMID:19870481. |
lesions following nasal instillation of virus appear first in the olfactory bulbs on the 3rd day, in the piriform lobes on the 4th, and in ammon's horn on the 5th day. |
2010-06-23 |
2023-08-12 |
mouse |
A B Sabin, R War. THE NATURAL HISTORY OF HUMAN POLIOMYELITIS : I. DISTRIBUTION OF VIRUS IN NERVOUS AND NON-NERVOUS TISSUES. The Journal of experimental medicine. vol 73. issue 6. 2010-06-23. PMID:19871111. |
the absence of demonstrable virus in the nasal mucosa, olfactory bulbs, and anterior perforated substance suggests that neither the upper respiratory tract nor the olfactory pathway were affected in the cases of human poliomyelitis studied in the present investigation. |
2010-06-23 |
2023-08-12 |
human |
S Flexne. RESPIRATORY VERSUS GASTRO-INTESTINAL INFECTION IN POLIOMYELITIS. The Journal of experimental medicine. vol 63. issue 2. 2010-06-22. PMID:19870468. |
on the basis of the experiments reported in this paper we can reaffirm the conclusion previously arrived at by ourselves, and confirmed independently by investigators in europe and america, namely that the only established portal of entry of the virus of poliomyelitis into the central nervous system of man is the nasal membrane, and especially the olfactory nervous areas in that membrane. |
2010-06-22 |
2023-08-12 |
human |
A B Sabin, P K Olitsk. INFLUENCE OF HOST FACTORS ON NEUROINVASIVENESS OF VESICULAR STOMATITIS VIRUS : III. EFFECT OF AGE AND PATHWAY OF INFECTION ON THE CHARACTER AND LOCALIZATION OF LESIONS IN THE CENTRAL NERVOUS SYSTEM. The Journal of experimental medicine. vol 67. issue 2. 2010-06-22. PMID:19870715. |
thus, in young mice, nasal instillation of the virus was followed by necrosis of a long chain of neurons, starting with those in the olfactory mucosa and progressing through specific zones of the olfactory pathway, pursuing the same order in which the various regions are known to have their major connections with one another. |
2010-06-22 |
2023-08-12 |
mouse |
A B Sabin, P K Olitsk. INFLUENCE OF HOST FACTORS ON NEUROINVASIVENESS OF VESICULAR STOMATITIS VIRUS : III. EFFECT OF AGE AND PATHWAY OF INFECTION ON THE CHARACTER AND LOCALIZATION OF LESIONS IN THE CENTRAL NERVOUS SYSTEM. The Journal of experimental medicine. vol 67. issue 2. 2010-06-22. PMID:19870715. |
invades the central nervous system in the majority of instances, by being eliminated on the nasal mucosa and then along the olfactory pathways (18), while the latter appears to employ chiefly the local sensory fibers, attacking primarily the neurons in the spinal ganglia (unpublished observations). |
2010-06-22 |
2023-08-12 |
mouse |
A B Sabin, P K Olitsk. FATE OF NASALLY INSTILLED POLIOMYELITIS VIRUS IN NORMAL AND CONVALESCENT MONKEYS WITH SPECIAL REFERENCE TO THE PROBLEM OF HOST TO HOST TRANSMISSION. The Journal of experimental medicine. vol 68. issue 1. 2010-06-22. PMID:19870774. |
after nasal instillation of virus in normal monkeys, it disappeared quickly (4 hours or less) and could be recovered neither from the excised nasal mucosa nor from the olfactory bulbs during the first 48 hours. |
2010-06-22 |
2023-08-12 |
monkey |
A B Sabin, P K Olitsk. FATE OF NASALLY INSTILLED POLIOMYELITIS VIRUS IN NORMAL AND CONVALESCENT MONKEYS WITH SPECIAL REFERENCE TO THE PROBLEM OF HOST TO HOST TRANSMISSION. The Journal of experimental medicine. vol 68. issue 1. 2010-06-22. PMID:19870774. |
at 72 hours, just before or coincident with the first rise of temperature, virus was found in very small amounts in the nasal mucosa and for the first time also in the olfactory bulbs. |
2010-06-22 |
2023-08-12 |
monkey |
A B Sabin, P K Olitsk. FATE OF NASALLY INSTILLED POLIOMYELITIS VIRUS IN NORMAL AND CONVALESCENT MONKEYS WITH SPECIAL REFERENCE TO THE PROBLEM OF HOST TO HOST TRANSMISSION. The Journal of experimental medicine. vol 68. issue 1. 2010-06-22. PMID:19870774. |
at 96 hours, at least 3 days before the appearance of nervous signs, and later, while virus continued to be present in considerable amounts in the olfactory bulbs (and presumably elsewhere in the central nervous system), none was detected in the nasal mucosa. |
2010-06-22 |
2023-08-12 |
monkey |
A B Sabin, R War. THE NATURAL HISTORY OF EXPERIMENTAL POLIOMYELITIS INFECTION : I. STUDIES ON THE CENTRIFUGAL SPREAD AND ELIMINATION OF VIRUS IN INTRASCIATICALLY INOCULATED RHESUS MONKEYS. The Journal of experimental medicine. vol 75. issue 1. 2010-06-22. PMID:19871162. |
no virus was found in the olfactory bulbs, nasal mucosa, tonsils and adjacent pharyngeal tissue, salivary glands, adrenals, superior cervical sympathetic ganglia, abdominal celiac ganglia, and small intestine. |
2010-06-22 |
2023-08-12 |
monkey |
Andreas Schmid, Martina Pyrski, Martin Biel, Trese Leinders-Zufall, Frank Zufal. Grueneberg ganglion neurons are finely tuned cold sensors. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 22. 2010-06-21. PMID:20519530. |
the grueneberg ganglion is a newly appreciated nasal subsystem with neural connections to the olfactory forebrain, but its functional role has not been well defined. |
2010-06-21 |
2023-08-12 |
mouse |
M Preusser, M Hutterer, M Sohm, O Koperek, K Elandt, K Dieckmann, D Prayer, C Maros. Disease stabilization of progressive olfactory neuroblastoma (esthesioneuroblastoma) under treatment with sunitinib mesylate. Journal of neuro-oncology. vol 97. issue 2. 2010-06-14. PMID:19820899. |
olfactory neuroblastoma (esthesioneuroblastoma) is a rare neoplasm of the olfactory epithelium in the upper nasal cavity. |
2010-06-14 |
2023-08-12 |
Not clear |
Richard L Abel, James S Maclaine, Ross Cotton, Viet Bui Xuan, Timothy B Nickels, Thomas H Clark, Zhijin Wang, Jonathan P L Co. Functional morphology of the nasal region of a hammerhead shark. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology. vol 155. issue 4. 2010-06-03. PMID:19883784. |
major and minor nasal grooves, as well as directing flow into the olfactory chamber, can, in conjunction with the nasal bridge separating incurrent and excurrent nostrils, limit flow passing into the olfactory chamber, possibly to protect the delicate nasal structures. |
2010-06-03 |
2023-08-12 |
Not clear |
Ning Xu, Balasubramanian Bhagavath, Hyung-Goo Kim, Lisa Halvorson, Robert S Podolsky, Lynn P Chorich, Puttur Prasad, Wen-Cheng Xiong, Richard S Cameron, Lawrence C Layma. NELF is a nuclear protein involved in hypothalamic GnRH neuronal migration. Molecular and cellular endocrinology. vol 319. issue 1-2. 2010-06-02. PMID:20025934. |
nasal embryonic lhrh factor (nelf) has been hypothesized to participate in the migration of gnrh and olfactory neurons into the forebrain, a prerequisite for normal hypothalamic-pituitary-gonadal function in puberty and reproduction. |
2010-06-02 |
2023-08-12 |
human |
Matthew W Himmelstein, Thomas A Kegelman, Michael P DeLorme, Nancy E Everds, John C O'Connor, Raymond A Kemper, Diane L Nabb, Beth E Mileson, Christopher Beva. Two-day inhalation toxicity study of methyl iodide in the rat. Inhalation toxicology. vol 21. issue 6. 2010-05-25. PMID:19519148. |
a dose- and time-dependent reduction in gsh levels in blood, kidney, liver, and nasal tissue was observed, with the greatest reduction in nasal tissue (olfactory and respiratory epithelium). |
2010-05-25 |
2023-08-12 |
rat |
Beth E Mileson, Lisa M Sweeney, Michael L Gargas, John Kinzel. Iodomethane human health risk characterization. Inhalation toxicology. vol 21. issue 6. 2010-05-25. PMID:19519156. |
nasal olfactory degeneration is the primary endpoint for risk assessment of acute exposure to iodomethane. |
2010-05-25 |
2023-08-12 |
human |
Kyu-Sup Cho, Duk-Gyu Lee, Kyung Un Choi, Hwan-Jung Ro. Primary olfactory neuroblastoma originating from the posterior nasal septum. Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery. vol 142. issue 5. 2010-05-06. PMID:20416476. |
primary olfactory neuroblastoma originating from the posterior nasal septum. |
2010-05-06 |
2023-08-12 |
Not clear |
Jean-Marie Heydel, Elzbieta J Holsztynska, Arièle Legendre, Nicolas Thiebaud, Yves Artur, Anne-Marie Le Bo. UDP-glucuronosyltransferases (UGTs) in neuro-olfactory tissues: expression, regulation, and function. Drug metabolism reviews. vol 42. issue 1. 2010-05-03. PMID:20067364. |
since there is evidence of the transfer of xenobiotics to the brain through the nasal pathway, circumventing the blood-brain barrier, olfactory ugts doubtlessly share the common function of detoxification, but they are also involved in the metabolism and turnover of exogenous or endogenous compounds critical for physiological olfactory processing in these tissues. |
2010-05-03 |
2023-08-12 |
mouse |
Jeffry D Schroeter, Guilherme J M Garcia, Julia S Kimbel. A computational fluid dynamics approach to assess interhuman variability in hydrogen sulfide nasal dosimetry. Inhalation toxicology. vol 22. issue 4. 2010-04-30. PMID:20064104. |
using nasal computational fluid dynamics (cfd) models, a correlation was found between wall mass flux and olfactory neuronal loss in rodents, suggesting an influence of airflow patterns on lesion locations that may affect interspecies extrapolation of inhaled dose. |
2010-04-30 |
2023-08-12 |
human |