| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xiaomei Wang, Haibing He, Wei Leng, Xing Tan. Evaluation of brain-targeting for the nasal delivery of estradiol by the microdialysis method. International journal of pharmaceutics. vol 317. issue 1. 2006-12-12. PMID:16631329. |
all these results indicate that estradiol is transported into csf via olfactory neurons, and, hence, there is a direct transport route from the nasal cavity into the csf for estradiol. |
2006-12-12 |
2023-08-12 |
rat |
| Wendy E Grus, Jianzhi Zhan. Origin and evolution of the vertebrate vomeronasal system viewed through system-specific genes. BioEssays : news and reviews in molecular, cellular and developmental biology. vol 28. issue 7. 2006-11-29. PMID:16850401. |
tetrapods have two distinct nasal chemosensory systems, the main olfactory system and the vomeronasal system (vns). |
2006-11-29 |
2023-08-12 |
Not clear |
| Gérard Bran. Olfactory/trigeminal interactions in nasal chemoreception. Neuroscience and biobehavioral reviews. vol 30. issue 7. 2006-11-28. PMID:16545453. |
for a long time, studies devoted to intranasal chemoreception have separately considered the different systems which coexist in the human nasal cavity, especially the olfactory and trigeminal systems. |
2006-11-28 |
2023-08-12 |
human |
| Gérard Bran. Olfactory/trigeminal interactions in nasal chemoreception. Neuroscience and biobehavioral reviews. vol 30. issue 7. 2006-11-28. PMID:16545453. |
indeed, most odorant molecules have the propensity to simultaneously stimulate olfactory and trigeminal systems in the nasal cavity. |
2006-11-28 |
2023-08-12 |
human |
| Anthony A Carboni, Kay J Cullen, William G Lavell. The effects of zinc on the olfactory neuroepithelium and olfactory bulbs of the Sprague-Dawley rat after oral administration of zinc-gluconate trihydrate. American journal of rhinology. vol 20. issue 3. 2006-11-28. PMID:16871926. |
the nasopharyngeal area, which includes the respiratory epithelium, mucosa, and the olfactory neuroepithelium (one), is a first-line of defense against airborne viruses and allergens, some of which manage to penetrate the nasal mucosa and invade the tissues of the nasal respiratory epithelium. |
2006-11-28 |
2023-08-12 |
human |
| Kai Zhao, Edmund A Pribitkin, Beverly J Cowart, David Rosen, Peter W Scherer, Pamela Dalto. Numerical modeling of nasal obstruction and endoscopic surgical intervention: outcome to airflow and olfaction. American journal of rhinology. vol 20. issue 3. 2006-11-28. PMID:16871935. |
surgical removal of nasal obstruction may facilitate the recovery of olfactory ability. |
2006-11-28 |
2023-08-12 |
Not clear |
| H Shi, C Kleinstreuer, Z Zhan. Laminar airflow and nanoparticle or vapor deposition in a human nasal cavity model. Journal of biomechanical engineering. vol 128. issue 5. 2006-11-28. PMID:16995756. |
of special interest is the olfactory region where the narrow channel surfaces receive only about one-half of a percent of the inhaled nanoparticles because the airflow bypasses these recesses located in the superior-most portions in the geometrically complex nasal cavities. |
2006-11-28 |
2023-08-12 |
human |
| Anne Hansen, Barbara S Zielinsk. Diversity in the olfactory epithelium of bony fishes: development, lamellar arrangement, sensory neuron cell types and transduction components. Journal of neurocytology. vol 34. issue 3-5. 2006-10-19. PMID:16841163. |
these topics comprise (1) the gross anatomy of the peripheral olfactory organ, including olfactory sensory neuron subtypes and their functional parameters, (2) the ultrastructure of the olfactory epithelium, and (3) recent findings regarding the development of the nasal cavity and the olfactory epithelium. |
2006-10-19 |
2023-08-12 |
zebrafish |
| Anne Hansen, Barbara S Zielinsk. Diversity in the olfactory epithelium of bony fishes: development, lamellar arrangement, sensory neuron cell types and transduction components. Journal of neurocytology. vol 34. issue 3-5. 2006-10-19. PMID:16841163. |
diverse species ventilate the olfactory chamber with a single accessory nasal sac, whereas the presence of two sacs is confined to species within the acanthopterygii. |
2006-10-19 |
2023-08-12 |
zebrafish |
| P Pahn Pataramekin, Esmail Meisam. Cytochrome oxidase staining reveals functionally important activity bands in the olfactory epithelium of newborn rat. Journal of neurocytology. vol 34. issue 3-5. 2006-10-19. PMID:16841167. |
nasal olfactory tissue of neonatal rats was stained with cytox and analyzed qualitatively and quantitatively. |
2006-10-19 |
2023-08-12 |
rat |
| Mathieu Gelhaye, Marie Trabalon, Jean-Marc Martrette, Christine Legrand-Fross. Effects of early olfactory deprivation on novelty-seeking behavior and primary and secondary lymphoid organs in young rats. Psychoneuroendocrinology. vol 31. issue 8. 2006-10-12. PMID:16890376. |
animals exposed to nasal obstruction presented an increased plasma corticosterone level, an adrenal hypertrophy more marked in females (+68% in females and +29% in males compared to sham group), a reduced growth of olfactory bulbs only in females (-43% compared to sham group) and an impaired novelty-seeking behavior, which seemed also more marked in females. |
2006-10-12 |
2023-08-12 |
rat |
| Mathieu Gelhaye, Marie Trabalon, Jean-Marc Martrette, Christine Legrand-Fross. Effects of early olfactory deprivation on novelty-seeking behavior and primary and secondary lymphoid organs in young rats. Psychoneuroendocrinology. vol 31. issue 8. 2006-10-12. PMID:16890376. |
these data showed that early olfactory deprivation by nasal obstruction was associated with some behavioral, endocrine and immunological alterations, which may have serious consequences for the health and the social status of the individuals. |
2006-10-12 |
2023-08-12 |
rat |
| Ignacio Salazar, Pablo Sanchez-Quinteiro, Jose Manuel Cifuentes, Patricia Fernandez De Troconi. General organization of the perinatal and adult accessory olfactory bulb in mice. The anatomical record. Part A, Discoveries in molecular, cellular, and evolutionary biology. vol 288. issue 9. 2006-10-12. PMID:16892425. |
therefore, it seems reasonable to establish the corresponding differences between a well-developed vomeronasal system and other areas of the nasal cavity in which putative olfactory receptors, perhaps present in other kinds of mammals, may be able to detect pheromones and to process them. |
2006-10-12 |
2023-08-12 |
mouse |
| Yukari Hagiwara, Yuki I Kawamura, Kosuke Kataoka, Bibi Rahima, Raymond J Jackson, Katsuhiro Komase, Taeko Dohi, Prosper N Boyaka, Yoshifumi Takeda, Hiroshi Kiyono, Jerry R McGhee, Kohtaro Fujihash. A second generation of double mutant cholera toxin adjuvants: enhanced immunity without intracellular trafficking. Journal of immunology (Baltimore, Md. : 1950). vol 177. issue 5. 2006-10-05. PMID:16920941. |
nasal application of native cholera toxin (nct) as a mucosal adjuvant has potential toxicity for the cns through binding to gm1 gangliosides in the olfactory nerves. |
2006-10-05 |
2023-08-12 |
mouse |
| S Rochkind, A Shahar, D Fliss, D El-Ani, L Astachov, T Hayon, M Alon, R Zamostiano, O Ayalon, I E Biton, Y Cohen, R Halperin, D Schneider, A Oron, Z Nev. Development of a tissue-engineered composite implant for treating traumatic paraplegia in rats. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. vol 15. issue 2. 2006-10-03. PMID:16292587. |
neuronal xenogeneic cells from biopsies of adult nasal olfactory mucosa (nom) of human origin, or spinal cords of human embryos, were cultured in two consecutive stages: stationary cultures in a viscous semi-solid gel (nvr-n-gel) and in suspension on positively charged microcarriers (mcs). |
2006-10-03 |
2023-08-12 |
human |
| Nagendra V Chemuturi, Jon E Haraldsson, Thomas Prisinzano, Maureen Donova. Role of dopamine transporter (DAT) in dopamine transport across the nasal mucosa. Life sciences. vol 79. issue 14. 2006-09-29. PMID:16733058. |
portions of the nasal mucosa are innervated by olfactory neurons expressing dopamine transporter (dat) which is responsible for the uptake of dopamine within the central nervous system. |
2006-09-29 |
2023-08-12 |
cattle |
| Nagendra V Chemuturi, Jon E Haraldsson, Thomas Prisinzano, Maureen Donova. Role of dopamine transporter (DAT) in dopamine transport across the nasal mucosa. Life sciences. vol 79. issue 14. 2006-09-29. PMID:16733058. |
the objective of these studies was to study the role of dat in dopamine transport across the bovine olfactory and nasal respiratory mucosa. |
2006-09-29 |
2023-08-12 |
cattle |
| Qi-Zhi Zhang, Liu-Sheng Zha, Yan Zhang, Wen-Ming Jiang, Wei Lu, Zhen-Qi Shi, Xin-Guo Jiang, Shou-Kuan F. The brain targeting efficiency following nasally applied MPEG-PLA nanoparticles in rats. Journal of drug targeting. vol 14. issue 5. 2006-09-21. PMID:16882548. |
the olfactory bulb/plasma and csf/plasma concentration ratios were significantly higher (p < 0.05) after application of nanoparticles than those of the nasal solution, except the ratio in olfactory bulb at 5 min. |
2006-09-21 |
2023-08-12 |
rat |
| B A Walter, V A Valera, S Takahashi, T Ushik. The olfactory route for cerebrospinal fluid drainage into the peripheral lymphatic system. Neuropathology and applied neurobiology. vol 32. issue 4. 2006-09-19. PMID:16866984. |
drainage of the cerebrospinal fluid through the olfactory nerves into the nasal lymphatics has been suggested repeatedly. |
2006-09-19 |
2023-08-12 |
rat |
| B A Walter, V A Valera, S Takahashi, T Ushik. The olfactory route for cerebrospinal fluid drainage into the peripheral lymphatic system. Neuropathology and applied neurobiology. vol 32. issue 4. 2006-09-19. PMID:16866984. |
to investigate precisely the morphology of this pathway, india ink was injected into the subarachnoidal space of the rat brain, and samples including the olfactory bulbs, olfactory tracts and the nasal mucosa were observed by light and electron microscopy. |
2006-09-19 |
2023-08-12 |
rat |