| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mohammed E Choudhury, Kanta Mikami, Yuiko Nakanishi, Taisei Matsuura, Ryo Utsunomiya, Hajime Yano, Madoka Kubo, Rina Ando, Jun Iwanami, Masakatsu Yamashita, Masahiro Nagai, Junya Tanak. Insomnia and depressive behavior of MyD88-deficient mice: Relationships with altered microglial functions. Journal of neuroimmunology. vol 363. 2021-12-31. PMID:34971898. |
we determined monoamines in the prefrontal cortex (pfc) using high-performance liquid chromatography and observed a decreased content of serotonin in the pfc of myd88-ko mice. |
2021-12-31 |
2023-08-13 |
mouse |
| Mengge Bai, Heming Yu, Chong Chen, Xingzhe Xu, Yong He, Yue Wang, Yu Tian, Zhonghao Wu, Tianlan Lan, Yan Li, Xiangyu Chen, Zhi Chen, Libo Zhao, Liang Fang, Deyu Yang, Ke Cheng, Peng Xi. Pigment epithelium-derived factor may induce antidepressant phenotypes in mice by the prefrontal cortex. Neuroscience letters. 2021-12-29. PMID:34965441. |
we detected pfc metabolite levels by liquid chromatography-tandem mass spectrometry and found significant upregulation of 5-hydroxyindoleacetic acid, kynurenine, 5-hydroxytryptamine, ornithine and glutamine, and downregulation of 5-hydroxytryptophan, glutamic acid and aspartic acid in pedf-overexpressing mice compared with control mice, in which no such changes were detected. |
2021-12-29 |
2023-08-13 |
mouse |
| Jingjing Xie, Xiaoyun Qin, Liqin Shu, Peixuan Li, Zijian Liu, Peng Zhu, Fangbiao Tao, Kun Huan. Caesarean section and offspring's emotional development: Sex differences and the role of key neurotransmitters. Brain research. vol 1767. 2021-12-09. PMID:34144003. |
offspring's prefrontal cortex was collected for he staining and assessment for da, hva, 5-ht, 5-hiaa. |
2021-12-09 |
2023-08-13 |
mouse |
| María Espinosa-Velasco, Marina D Reguilón, Marina Bellot, Núria Nadal-Gratacós, Xavier Berzosa, Pol Puigseslloses, Cristian Gómez-Canela, Marta Rodríguez-Arias, David Pubill, Jordi Camarasa, Elena Escubedo, Raúl López-Arna. Behavioural and neurochemical effects after repeated administration of N-ethylpentylone (ephylone) in mice. Journal of neurochemistry. 2021-12-08. PMID:34816436. |
moreover, nep induced hyperthermia as well as depressive-like symptoms after repeated administrations that may be related to the decrease in serotonin and noradrenaline levels observed in striatum and pfc. |
2021-12-08 |
2023-08-13 |
mouse |
| Lu Wang, Min Zhang, Jing Wen, Yalan Xiang, Xiaoyu Duan, Changwei Yu, Miao Yan, Bikui Zhang, Pingfei Fan. Isoliquiritigenin Alleviates Semen Strychni-Induced Neurotoxicity by Restoring the Metabolic Pathway of Neurotransmitters in Rats. Frontiers in pharmacology. vol 12. 2021-12-07. PMID:34867385. |
the concentration of monoamines, amino acids, and choline neurotransmitters, the dopamine (da) and 5-hydroxytryptamine (5-ht) metabolic pathway in the hippocampus, cerebellum, striatum, prefrontal cortex, hypothalamus, serum, and plasma were detected by lc-ms/ms. |
2021-12-07 |
2023-08-13 |
rat |
| Tabinda Salman, Rushda Afroz, Shazia Nawaz, Khalid Mahmood, Darakhshan J Haleem, Shamshad Zarin. Differential effects of memory enhancing and impairing doses of methylphenidate on serotonin metabolism and 5-HT1A, GABA, glutamate receptor expression in the rat prefrontal cortex. Biochimie. vol 191. 2021-11-29. PMID:34454977. |
differential effects of memory enhancing and impairing doses of methylphenidate on serotonin metabolism and 5-ht1a, gaba, glutamate receptor expression in the rat prefrontal cortex. |
2021-11-29 |
2023-08-13 |
rat |
| Tabinda Salman, Rushda Afroz, Shazia Nawaz, Khalid Mahmood, Darakhshan J Haleem, Shamshad Zarin. Differential effects of memory enhancing and impairing doses of methylphenidate on serotonin metabolism and 5-HT1A, GABA, glutamate receptor expression in the rat prefrontal cortex. Biochimie. vol 191. 2021-11-29. PMID:34454977. |
to understand neurochemical mechanisms and receptors involved in memory enhancing and impairing effects of mpd, the present study concerns the effects of these doses of mpd on serotonin, 5-ht1a, gaba, and nmda receptor mrna expression in the prefrontal cortex (pfc). |
2021-11-29 |
2023-08-13 |
rat |
| Tabinda Salman, Rushda Afroz, Shazia Nawaz, Khalid Mahmood, Darakhshan J Haleem, Shamshad Zarin. Differential effects of memory enhancing and impairing doses of methylphenidate on serotonin metabolism and 5-HT1A, GABA, glutamate receptor expression in the rat prefrontal cortex. Biochimie. vol 191. 2021-11-29. PMID:34454977. |
animals showing improved performance had high 5-ht metabolism in the pfc while these levels were not affected in the group treated with higher mpd doses and exhibiting impaired memory. |
2021-11-29 |
2023-08-13 |
rat |
| Mathilde Baudat, Anne R de Kort, Daniel L A van den Hove, Elbert A J Jooste. Early-life exposure to selective serotonin reuptake inhibitors: long-term effects on pain and affective comorbidities. The European journal of neuroscience. 2021-11-29. PMID:34841582. |
thus, the aim of this review is to understand how early-life selective serotonin reuptake inhibitor exposure alters the developing prefrontal cortex and amygdala, and thereby underlies the long-term changes in pain and its affective comorbidities in later life. |
2021-11-29 |
2023-08-13 |
Not clear |
| Mathilde Baudat, Anne R de Kort, Daniel L A van den Hove, Elbert A J Jooste. Early-life exposure to selective serotonin reuptake inhibitors: long-term effects on pain and affective comorbidities. The European journal of neuroscience. 2021-11-29. PMID:34841582. |
third, early-life selective serotonin reuptake inhibitor exposure alters serotonergic levels, transcription factors expression and brain derived neurotrophic factor levels, resulting in hyperconnectivity within the amygdala and the prefrontal cortex. |
2021-11-29 |
2023-08-13 |
Not clear |
| Mathilde Baudat, Anne R de Kort, Daniel L A van den Hove, Elbert A J Jooste. Early-life exposure to selective serotonin reuptake inhibitors: long-term effects on pain and affective comorbidities. The European journal of neuroscience. 2021-11-29. PMID:34841582. |
we conclude that early-life selective serotonin reuptake inhibitor exposure affects the maturation of prefrontal cortex and amygdala circuits and thereby enhances their anti-nociceptive inputs in the spinal cord. |
2021-11-29 |
2023-08-13 |
Not clear |
| Hakimeh Saadati, Farshid Sadegzadeh, Nona Sakhaie, Hamdollah Panahpour, Mohsen Sagh. Serotonin depletion during the postnatal developmental period causes behavioral and cognitive alterations and decreases BDNF level in the brain of rats. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 81. issue 2. 2021-11-18. PMID:33404066. |
therefore, in the present study, we examined the effects of postnatal days (pnd 10-20) administration of para-chlorophenylalanine (pcpa, 100 mg/kg, s.c) a 5-ht synthesis inhibitor, on anxiety-related behaviors, pain sensitivity, short-term recognition memory, and hippocampal and prefrontal cortex (pfc) brain-derived neurotrophic factor (bdnf) mrna expression in adult male and female rats. |
2021-11-18 |
2023-08-13 |
rat |
| Hakimeh Saadati, Farshid Sadegzadeh, Nona Sakhaie, Hamdollah Panahpour, Mohsen Sagh. Serotonin depletion during the postnatal developmental period causes behavioral and cognitive alterations and decreases BDNF level in the brain of rats. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 81. issue 2. 2021-11-18. PMID:33404066. |
in addition, postnatal days serotonin depletion decreased bdnf level in the hippocampus and pfc of both male and female rats. |
2021-11-18 |
2023-08-13 |
rat |
| Joanna Kowalczyk, Modestos Nakos-Bimpos, Alexia Polissidis, Christina Dalla, Nikolaos Kokras, Krystyna Skalicka-Wozniak, Barbara Budzynsk. Xanthotoxin affects depression-related behavior and neurotransmitters content in a sex-dependent manner in mice. Behavioural brain research. vol 399. 2021-11-15. PMID:33144177. |
the immobility level was lower in females than males, which may be associated with a higher serotonin level in the female prefrontal cortex. |
2021-11-15 |
2023-08-13 |
mouse |
| Joanna Kowalczyk, Modestos Nakos-Bimpos, Alexia Polissidis, Christina Dalla, Nikolaos Kokras, Krystyna Skalicka-Wozniak, Barbara Budzynsk. Xanthotoxin affects depression-related behavior and neurotransmitters content in a sex-dependent manner in mice. Behavioural brain research. vol 399. 2021-11-15. PMID:33144177. |
a dose-dependent increase of serotonin and noradrenaline was reported in the reverse-phase ion-pair liquid chromatography in the female prefrontal cortex but not in the hippocampus. |
2021-11-15 |
2023-08-13 |
mouse |
| Joanna Kowalczyk, Modestos Nakos-Bimpos, Alexia Polissidis, Christina Dalla, Nikolaos Kokras, Krystyna Skalicka-Wozniak, Barbara Budzynsk. Xanthotoxin affects depression-related behavior and neurotransmitters content in a sex-dependent manner in mice. Behavioural brain research. vol 399. 2021-11-15. PMID:33144177. |
the increasing level of serotonin in the male and female prefrontal cortex may underlie this effect. |
2021-11-15 |
2023-08-13 |
mouse |
| Trevor J Buhr, Carter H Reed, Allyse Shoeman, Ella E Bauer, Rudy J Valentine, Peter J Clar. The Influence of Moderate Physical Activity on Brain Monoaminergic Responses to Binge-Patterned Alcohol Ingestion in Female Mice. Frontiers in behavioral neuroscience. vol 15. 2021-11-11. PMID:33716684. |
moreover, daily running wheel access only mildly influenced alcohol-related norepinephrine concentrations in the hypothalamus and prefrontal cortex, as well as serotonin turnover in the hippocampus. |
2021-11-11 |
2023-08-13 |
mouse |
| Xiao-Ju Liu, Hai-Juan Wang, Xiao-Yu Wang, Yin-Xia Ning, Jie Ga. GABABR1 in DRN mediated GABA to regulate 5-HT expression in multiple brain regions in male rats with high and low aggressive behavior. Neurochemistry international. vol 150. 2021-11-11. PMID:34509561. |
on this basis, gaba content in the drn and 5-ht contents in the pfc, hypothalamus, hippocampus and drn were detected using elisa. |
2021-11-11 |
2023-08-13 |
rat |
| Xiao-Ju Liu, Hai-Juan Wang, Xiao-Yu Wang, Yin-Xia Ning, Jie Ga. GABABR1 in DRN mediated GABA to regulate 5-HT expression in multiple brain regions in male rats with high and low aggressive behavior. Neurochemistry international. vol 150. 2021-11-11. PMID:34509561. |
changes in 5-ht levels in the pfc, hypothalamus and hippocampus were detected afterward. |
2021-11-11 |
2023-08-13 |
rat |
| Xiao-Ju Liu, Hai-Juan Wang, Xiao-Yu Wang, Yin-Xia Ning, Jie Ga. GABABR1 in DRN mediated GABA to regulate 5-HT expression in multiple brain regions in male rats with high and low aggressive behavior. Neurochemistry international. vol 150. 2021-11-11. PMID:34509561. |
the contents of 5-ht in the pfc, hypothalamus and hippocampus of rats with high and low aggressive behavior (no difference between the two groups) were significantly decreased, but the change in gaba content in the drn was the opposite. |
2021-11-11 |
2023-08-13 |
rat |