| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Michael Notaras, Aiman Lodhi, Estibaliz Barrio-Alonso, Careen Foord, Tori Rodrick, Drew Jones, Haoyun Fang, David Greening, Dilek Cola. Neurodevelopmental signatures of narcotic and neuropsychiatric risk factors in 3D human-derived forebrain organoids. Molecular psychiatry. 2021-06-23. PMID:34158620. |
while synthetic cannabinoids can differ from naturally occurring compounds in their effects, our data nonetheless suggests that exposure to win 55,212-2 elicits neurotoxicity within human-derived developing forebrain tissue. |
2021-06-23 |
2023-08-13 |
human |
| Diego Pascual Cuadrado, Anna Wierczeiko, Charlotte Hewel, Susanne Gerber, Beat Lut. Dichotomic Hippocampal Transcriptome After Glutamatergic vs. GABAergic Deletion of the Cannabinoid CB1 Receptor. Frontiers in synaptic neuroscience. vol 13. 2021-04-28. PMID:33897403. |
we used genetically engineered mouse lines that lack the cannabinoid type-1 receptor (cb1) either in dorsal telencephalic glutamatergic or in forebrain gabaergic neurons to create new allostatic states, resulting from alterations in the excitatory/inhibitory (e/i) balance. |
2021-04-28 |
2023-08-13 |
mouse |
| Liane I F Moura, Cristina Lemos, Catherine Ledent, Eugénia Carvalho, Attila Köfalv. Chronic insulinopenia/hyperglycemia decreases cannabinoid CB Brain research bulletin. vol 147. 2020-04-06. PMID:30721768. |
here we asked how glucose metabolism and important facets of insulin signaling are affected in the forebrain of cannabinoid cb |
2020-04-06 |
2023-08-13 |
Not clear |
| Rafael M Bitencourt, Alán Alpár, Valentina Cinquina, Samira G Ferreira, Bárbara S Pinheiro, Cristina Lemos, Catherine Ledent, Reinaldo N Takahashi, Fernando J Sialana, Gert Lubec, Rodrigo A Cunha, Tibor Harkany, Attila Köfalv. Lack of presynaptic interaction between glucocorticoid and CB1 cannabinoid receptors in GABA- and glutamatergic terminals in the frontal cortex of laboratory rodents. Neurochemistry international. vol 90. 2016-09-20. PMID:26196379. |
corticosteroids can also modulate forebrain synapses by using endocannabinoid effector systems. |
2016-09-20 |
2023-08-13 |
mouse |
| Jongho Kim, Andrew G Horti, William B Mathews, Vladimir Pogorelov, Heather Valentine, James R Brasic, Daniel P Holt, Hayden T Ravert, Robert F Dannals, Luewi Zhou, Bruno Jedynak, Atsushi Kamiya, Mikhail V Pletnikov, Dean F Won. Quantitative Multi-modal Brain Autoradiography of Glutamatergic, Dopaminergic, Cannabinoid, and Nicotinic Receptors in Mutant Disrupted-In-Schizophrenia-1 (DISC1) Mice. Molecular imaging and biology. vol 17. issue 3. 2016-03-08. PMID:25296765. |
we hypothesized that the mutant disc1 alters the homeostasis of multi-receptor interactions between dopaminergic [dopamine 2/3 (d(2/3)r)], glutamatergic [metabotropic glutamate 5 (mglur5)], cannabinoid 1 (cb(1)r), and nicotinic acetylcholine (α4β2-nachr) receptors in the brains of mice with inducible forebrain neuronal expression of dominant-negative mutant disc1. |
2016-03-08 |
2023-08-13 |
mouse |
| Gaurav Bedse, Adele Romano, Bianca Tempesta, Michele A Lavecchia, Lorenzo Pace, Antonello Bellomo, Andrea Duranti, Maria Vittoria Micioni Di Bonaventura, Carlo Cifani, Tommaso Cassano, Silvana Gaetan. Inhibition of anandamide hydrolysis enhances noradrenergic and GABAergic transmission in the prefrontal cortex and basolateral amygdala of rats subjected to acute swim stress. Journal of neuroscience research. vol 93. issue 5. 2015-11-25. PMID:25581607. |
limbic forebrain endocannabinoid (ecb) signaling is critically involved in stress integration by modulating neurotransmitters release. |
2015-11-25 |
2023-08-13 |
rat |
| Jason M Wiebelhaus, Travis W Grim, Robert A Owens, Matthew F Lazenka, Laura J Sim-Selley, Rehab A Abdullah, Micah J Niphakis, Robert E Vann, Benjamin F Cravatt, Jenny L Wiley, S Stevens Negus, Aron H Lichtma. Δ9-tetrahydrocannabinol and endocannabinoid degradative enzyme inhibitors attenuate intracranial self-stimulation in mice. The Journal of pharmacology and experimental therapeutics. vol 352. issue 2. 2015-07-08. PMID:25398241. |
in this study, we investigated the impact of thc and inhibitors of the endocannabinoid hydrolytic enzymes fatty acid amide hydrolase (faah) and monoacylglycerol lipase (magl) on operant responding for electrical stimulation of the medial forebrain bundle [intracranial self-stimulation (icss)], which is known to activate the mesolimbic dopamine system. |
2015-07-08 |
2023-08-13 |
mouse |
| Ilaria Belluomo, Isabelle Matias, Camille Pernègre, Giovanni Marsicano, Francis Chaoulof. Opposite control of frontocortical 2-arachidonoylglycerol turnover rate by cannabinoid type-1 receptors located on glutamatergic neurons and on astrocytes. Journal of neurochemistry. vol 133. issue 1. 2015-05-27. PMID:25626460. |
this study examined the respective influences of cannabinoid type-1 (cb1) receptors expressed either in forebrain gabaergic neurons, in cortical glutamatergic neurons, or in astrocytes on the turnover rates of the endocannabinoids n-arachidonoylethanolamide (aea) and 2-arachidonoylglycerol (2-ag), and the non-cannabinoid n-acylethanolamides, palmitoylethanolamide (pea), and oleoylethanolamide (oea), in mouse forebrain regions. |
2015-05-27 |
2023-08-13 |
mouse |
| Russell L Carr, Casey A Graves, Lee C Mangum, Carole A Nail, Matthew K Ros. Low level chlorpyrifos exposure increases anandamide accumulation in juvenile rat brain in the absence of brain cholinesterase inhibition. Neurotoxicology. vol 43. 2015-04-17. PMID:24373905. |
we have previously reported that repeated exposure to cpf results in greater inhibition of fatty acid amide hydrolase (faah), the enzyme that metabolizes the endocannabinoid anandamide (aea), than inhibition of either forebrain che or monoacylglycerol lipase (magl), the enzyme that metabolizes the endocannabinoid 2-arachidonylglycerol (2-ag). |
2015-04-17 |
2023-08-12 |
rat |
| Huikun Wang, Carl R Lupic. Release of endogenous cannabinoids from ventral tegmental area dopamine neurons and the modulation of synaptic processes. Progress in neuro-psychopharmacology & biological psychiatry. vol 52. 2014-12-12. PMID:24495779. |
during reward- and reinforcement-related behavior dopamine levels increase in forebrain areas and this has recently been shown to be modulated by the endocannabinoid system. |
2014-12-12 |
2023-08-12 |
Not clear |
| Liangfang Zhao, Eric S Levin. BDNF-endocannabinoid interactions at neocortical inhibitory synapses require phospholipase C signaling. Journal of neurophysiology. vol 111. issue 5. 2014-10-30. PMID:24335212. |
endogenous cannabinoids (endocannabinoids) and neurotrophins, particularly brain-derived neurotrophic factor (bdnf), are potent synaptic modulators that are expressed throughout the forebrain and play critical roles in many behavioral processes. |
2014-10-30 |
2023-08-12 |
mouse |
| Karine Thibault, Damien Carrel, Damien Bonnard, Katalin Gallatz, Anne Simon, Marc Biard, Sophie Pezet, Miklos Palkovits, Zsolt Lenke. Activation-dependent subcellular distribution patterns of CB1 cannabinoid receptors in the rat forebrain. Cerebral cortex (New York, N.Y. : 1991). vol 23. issue 11. 2014-08-14. PMID:22892424. |
activation-dependent subcellular distribution patterns of cb1 cannabinoid receptors in the rat forebrain. |
2014-08-14 |
2023-08-12 |
rat |
| László Köles, Pedro Garção, Zoltán S Zádori, Samira G Ferreira, Bárbara S Pinheiro, Carla S da Silva-Santos, Catherine Ledent, Attila Köfalv. Presynaptic TRPV1 vanilloid receptor function is age- but not CB1 cannabinoid receptor-dependent in the rodent forebrain. Brain research bulletin. vol 97. 2014-03-18. PMID:23831917. |
presynaptic trpv1 vanilloid receptor function is age- but not cb1 cannabinoid receptor-dependent in the rodent forebrain. |
2014-03-18 |
2023-08-12 |
mouse |
| Ken-ichi Tomiyama, Masahiko Funad. Cytotoxicity of synthetic cannabinoids on primary neuronal cells of the forebrain: the involvement of cannabinoid CB1 receptors and apoptotic cell death. Toxicology and applied pharmacology. vol 274. issue 1. 2014-02-24. PMID:24211273. |
these synthetic cannabinoids induced cytotoxicity in the forebrain cultures in a concentration-dependent manner. |
2014-02-24 |
2023-08-12 |
mouse |
| Ken-ichi Tomiyama, Masahiko Funad. Cytotoxicity of synthetic cannabinoids on primary neuronal cells of the forebrain: the involvement of cannabinoid CB1 receptors and apoptotic cell death. Toxicology and applied pharmacology. vol 274. issue 1. 2014-02-24. PMID:24211273. |
cytotoxicity of synthetic cannabinoids on primary neuronal cells of the forebrain: the involvement of cannabinoid cb1 receptors and apoptotic cell death. |
2014-02-24 |
2023-08-12 |
mouse |
| Ken-ichi Tomiyama, Masahiko Funad. Cytotoxicity of synthetic cannabinoids on primary neuronal cells of the forebrain: the involvement of cannabinoid CB1 receptors and apoptotic cell death. Toxicology and applied pharmacology. vol 274. issue 1. 2014-02-24. PMID:24211273. |
these synthetic cannabinoids induced apoptosis through a caspase-3-dependent mechanism in the forebrain cultures. |
2014-02-24 |
2023-08-12 |
mouse |
| Ken-ichi Tomiyama, Masahiko Funad. Cytotoxicity of synthetic cannabinoids on primary neuronal cells of the forebrain: the involvement of cannabinoid CB1 receptors and apoptotic cell death. Toxicology and applied pharmacology. vol 274. issue 1. 2014-02-24. PMID:24211273. |
cytotoxicity induced by synthetic cannabinoid (cp-55,940, cp-47,497, cp-47,497-c8, hu-210, jwh-018, jwh-210, am-2201, and mam-2201) was examined using forebrain neuronal cultures. |
2014-02-24 |
2023-08-12 |
mouse |
| M Häring, M Grieb, K Monory, B Lutz, F A Moreir. Cannabinoid CB₁ receptor in the modulation of stress coping behavior in mice: the role of serotonin and different forebrain neuronal subpopulations. Neuropharmacology. vol 65. 2013-10-17. PMID:23000076. |
cannabinoid cb₁ receptor in the modulation of stress coping behavior in mice: the role of serotonin and different forebrain neuronal subpopulations. |
2013-10-17 |
2023-08-12 |
mouse |
| Ferenc Zádor, Ferenc Otvös, Sándor Benyhe, Andreas Zimmer, Eszter Páld. Inhibition of forebrain μ-opioid receptor signaling by low concentrations of rimonabant does not require cannabinoid receptors and directly involves μ-opioid receptors. Neurochemistry international. vol 61. issue 3. 2013-01-22. PMID:22613132. |
inhibition of forebrain μ-opioid receptor signaling by low concentrations of rimonabant does not require cannabinoid receptors and directly involves μ-opioid receptors. |
2013-01-22 |
2023-08-12 |
mouse |
| Teresa Morera-Herreras, Cristina Miguelez, Asier Aristieta, José Ángel Ruiz-Ortega, Luisa Uged. Endocannabinoid modulation of dopaminergic motor circuits. Frontiers in pharmacology. vol 3. 2012-10-02. PMID:22701427. |
there is substantial evidence supporting a role for the endocannabinoid system as a modulator of the dopaminergic activity in the basal ganglia, a forebrain system that integrates cortical information to coordinate motor activity regulating signals. |
2012-10-02 |
2023-08-12 |
Not clear |