| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Qaisar Ali Khan, Rohail Khan, Ravina Verma, Suchi D Shah, Bhavana Vattikuti, Aleena Z Khan, Andia Shahzadi, Parsa Abdi, Michelle Anthony, Christopher S Farkouh, Matthew Farkouh, Natalia Santiago, David Zepeda, Andrew Nune. Non-syndromic Intellectual Disability: An Experimental In-Depth Exploration of Inheritance Pattern, Phenotypic Presentation, and Genomic Composition. Cureus. vol 15. issue 1. 2023-02-27. PMID:36843831. |
three genes, cdk5r1, omg, and ev12a, were found on chromosome 17q11.2-q12 region of affected individuals in family a with high expression in the frontal cortex of the brain, hippocampus, and spinal cord, respectively. |
2023-02-27 |
2023-08-14 |
Not clear |
| N P Camacho-Hernández, F Peña-Orteg. Fractalkine/CX3CR1-Dependent Modulation of Synaptic and Network Plasticity in Health and Disease. Neural plasticity. vol 2023. 2023-01-16. PMID:36644710. |
thus, the absence of cx3cr1 or any failure in the fkn/cx3cr1 axis has been linked to alterations in different brain functions, including changes in synaptic and network plasticity in structures such as the hippocampus, cortex, brainstem, and spinal cord. |
2023-01-16 |
2023-08-14 |
Not clear |
| Ishan Sunilkumar Bhatt, Nicholas Wilson, Raquel Dias, Ali Torkaman. A genome-wide association study of tinnitus reveals shared genetic links to neuropsychiatric disorders. Scientific reports. vol 12. issue 1. 2022-12-29. PMID:36581688. |
the gwas signals for tinnitus were enriched in the hippocampus and cortex, and for tinnitus-related distress were enriched in the brain and spinal cord. |
2022-12-29 |
2023-08-14 |
human |
| Juan José Casañas, María Luz Montesino. Proteomic characterization of spinal cord synaptoneurosomes from Tg-SOD1/G93A mice supports a role for MNK1 and local translation in the early stages of amyotrophic lateral sclerosis. Molecular and cellular neurosciences. 2022-11-13. PMID:36372157. |
to characterize synaptic failure in the spinal cord (sc) in the tg-sod1/g93a mouse model of amyotrophic lateral sclerosis (als), we applied a method we originally designed to isolate cortical and hippocampal sns to sc tissue. |
2022-11-13 |
2023-08-14 |
mouse |
| Hongtao Zh. Structure and Mechanism of Glycine Receptor Elucidated by Cryo-Electron Microscopy. Frontiers in pharmacology. vol 13. 2022-08-26. PMID:36016557. |
glyrs are found in the central nervous system including the spinal cord, brain stem, and cerebellum, as well as in the retina, sperm, macrophages, hippocampus, cochlea, and liver. |
2022-08-26 |
2023-08-14 |
Not clear |
| Ozan Baytas, Julie A Kauer, Eric M Morro. Loss of mitochondrial enzyme GPT2 causes early neurodegeneration in locus coeruleus. Neurobiology of disease. 2022-07-31. PMID:35908744. |
we observe reduced noradrenergic projections to and norepinephrine levels in hippocampus and spinal cord. |
2022-07-31 |
2023-08-14 |
mouse |
| Ahad Karimzadeh Kalkhoran, Mohammad Reza Alipour, Mohsen Jafarzadehgharehziaaddin, Hamid Soltani Zangbar, Parviz Shahab. Intersection of hippocampus and spinal cord: a focus on the hippocampal alpha-synuclein accumulation, dopaminergic receptors, neurogenesis, and cognitive function following spinal cord injury in male rats. BMC neuroscience. vol 23. issue 1. 2022-07-12. PMID:35820831. |
intersection of hippocampus and spinal cord: a focus on the hippocampal alpha-synuclein accumulation, dopaminergic receptors, neurogenesis, and cognitive function following spinal cord injury in male rats. |
2022-07-12 |
2023-08-14 |
rat |
| Emmanuelle C Genin, Sylvie Bannwarth, Baptiste Ropert, Françoise Lespinasse, Alessandra Mauri-Crouzet, Gaelle Augé, Konstantina Fragaki, Charlotte Cochaud, Erminia Donnarumma, Sandra Lacas-Gervais, Timothy Wai, Véronique Paquis-Flucklinge. CHCHD10 and SLP2 control the stability of the PHB complex: a key factor for motor neuron viability. Brain : a journal of neurology. 2022-06-03. PMID:35656794. |
affected cells and tissues display instability of the phb complex which participates at least in part to the activation of the oma1 cascade with opa1 processing leading to mitochondrial fragmentation, abnormal mitochondrial cristae morphogenesis and neuronal death found in spinal cord and the hippocampus of chchd10s59l/+ animals. |
2022-06-03 |
2023-08-14 |
mouse |
| Chunyan Zhu, Yongping Zhu, Guoxin Zhang, Hongyan Wu, Yuqi Shi, Jiahao Li, Jun Yang, Zhiyun Mao, Qionghong Xu, Xuemin Yao, Xiaoxin Zhu, Jigang Wang, Xianguo Liu, Na Li. The analgesic and antidepressant properties of dihydroartemisinine in the neuropathic pain mice: By the downregulation of HnRNPA1 in the spinal cord and hippocampus. Clinical and translational medicine. vol 12. issue 2. 2022-02-27. PMID:35220669. |
the analgesic and antidepressant properties of dihydroartemisinine in the neuropathic pain mice: by the downregulation of hnrnpa1 in the spinal cord and hippocampus. |
2022-02-27 |
2023-08-13 |
mouse |
| Natalie Grima, Lyndal Henden, Owen Watson, Ian P Blair, Kelly L William. Simultaneous Isolation of High-Quality RNA and DNA From Postmortem Human Central Nervous System Tissues for Omics Studies. Journal of neuropathology and experimental neurology. 2021-12-23. PMID:34939123. |
motor cortex, frontal cortex, hippocampus, occipital cortex, anterior cingulate cortex, cerebellum, and spinal cord tissues were obtained from 22 individuals diagnosed with motor neuron disease (mnd) and 13 neurologically normal controls (n = 245 tissues). |
2021-12-23 |
2023-08-13 |
human |
| Ketlyn P da Motta, Beatriz F Santos, Nelson Luís De C Domingues, Cristiane Luchese, Ethel A Wilhel. Target enzymes in oxaliplatin-induced peripheral neuropathy in Swiss mice: A new acetylcholinesterase inhibitor as therapeutic strategy. Chemico-biological interactions. 2021-12-13. PMID:34896366. |
here, the negative correlation between the paw withdrawal threshold caused by oxa and acetylcholinesterase (ache) activity was demonstrated in the cortex, hippocampus, and spinal cord. |
2021-12-13 |
2023-08-13 |
mouse |
| Alexia Thamara Gasparin, Evelize Stacoviaki Rosa, Carlos Henrique Alves Jesus, Izonete Cristina Guiloski, Helena Cristina da Silva de Assis, Olair Carlos Beltrame, Rosângela Locatelli Dittrich, Samanta Daliana Golin Pacheco, Janaina Menezes Zanoveli, Joice Maria da Cunh. Bixin attenuates mechanical allodynia, anxious and depressive-like behaviors associated with experimental diabetes counteracting oxidative stress and glycated hemoglobin. Brain research. vol 1767. 2021-12-09. PMID:34107278. |
blood glycated hemoglobin (hba1) and the levels of lipid peroxidation (lpo) and reduced glutathione (gsh) were evaluated on the hippocampus, pre-frontal cortex, lumbar spinal cord, and sciatic nerve. |
2021-12-09 |
2023-08-13 |
rat |
| Zhiping Xie, Shaoxin Huang, Shenke Xie, Wu Zhou, Chengcai Li, Zelong Xing, Zhihua Wang, Zhiwu Wu, Meihua L. Potential Correlation Between Depression-like Behavior and the Mitogen-Activated Protein Kinase Pathway in the Rat Hippocampus Following Spinal Cord Injury. World neurosurgery. vol 154. 2021-12-09. PMID:34271150. |
depression induced by spinal cord injury (sci) has been demonstrated in clinical and experimental studies; it significantly impacts patients' lives and may be associated with changes in the hippocampus. |
2021-12-09 |
2023-08-13 |
rat |
| Daniela Silva Santos, Dirson João Stein, Helouise Richardt Medeiros, Fernanda Dos Santos Pereira, Isabel Cristina de Macedo, Felipe Fregni, Wolnei Caumo, Iraci L S Torre. Transcranial direct current stimulation alters anxious-like behavior and neural parameters in rats with chronic pain exposed to alcohol. Journal of psychiatric research. vol 144. 2021-12-07. PMID:34735841. |
rats were killed 24 h after the last behavioral assessment, and brain and spinal cord tissue samples were collected and processed for npy immunohistochemistry, expression of il1a and il1b in the spinal cord, cerebellum, and hippocampus, and levels of il-1α and il-1β in the same brain structures and the striatum. |
2021-12-07 |
2023-08-13 |
rat |
| Daniela Silva Santos, Dirson João Stein, Helouise Richardt Medeiros, Fernanda Dos Santos Pereira, Isabel Cristina de Macedo, Felipe Fregni, Wolnei Caumo, Iraci L S Torre. Transcranial direct current stimulation alters anxious-like behavior and neural parameters in rats with chronic pain exposed to alcohol. Journal of psychiatric research. vol 144. 2021-12-07. PMID:34735841. |
in addition, tdcs modulated the hypothalamic npy-immunoreactivity, increased the levels of il-1α in the hippocampus (like np and al), and increased the expression of il1b in the spinal cord (like al). |
2021-12-07 |
2023-08-13 |
rat |
| Ignacio Jure, Eugenia Falomir Lockhart, Alejandro F De Nicola, María Jose Bellini, Florencia Labombard. IGF1 Gene Therapy Reversed Cognitive Deficits and Restored Hippocampal Alterations After Chronic Spinal Cord Injury. Molecular neurobiology. vol 58. issue 12. 2021-12-03. PMID:34463925. |
igf1 gene therapy reversed cognitive deficits and restored hippocampal alterations after chronic spinal cord injury. |
2021-12-03 |
2023-08-13 |
Not clear |
| Ignacio Jure, Eugenia Falomir Lockhart, Alejandro F De Nicola, María Jose Bellini, Florencia Labombard. IGF1 Gene Therapy Reversed Cognitive Deficits and Restored Hippocampal Alterations After Chronic Spinal Cord Injury. Molecular neurobiology. vol 58. issue 12. 2021-12-03. PMID:34463925. |
in summary, rad-igf1 gene therapy might surge as a new therapeutic strategy for patients with hippocampal microglial alterations and cognitive deficits such as those with spinal cord injury and other neurodegenerative diseases. |
2021-12-03 |
2023-08-13 |
Not clear |
| Aruna Sharma, Lianyuan Feng, Dafin F Muresanu, Seaab Sahib, Z Ryan Tian, José Vicente Lafuente, Anca D Buzoianu, Rudy J Castellani, Ala Nozari, Lars Wiklund, Hari Shanker Sharm. Manganese nanoparticles induce blood-brain barrier disruption, cerebral blood flow reduction, edema formation and brain pathology associated with cognitive and motor dysfunctions. Progress in brain research. vol 265. 2021-11-24. PMID:34560926. |
at this time, bbb disruption, reduction in cerebral blood flow (cbf), brain edema formation and brain pathology were most marked in the sensory-motor cortex, hippocampus, caudate putamen, cerebellum and thalamus followed by hypothalamus, pons, medulla and spinal cord. |
2021-11-24 |
2023-08-13 |
rat |
| Jessica D Panes, Aline Wendt, Oscar Ramirez-Molina, Patricio A Castro, Jorge Fuentealb. Deciphering the role of PGC-1α in neurological disorders: from mitochondrial dysfunction to synaptic failure. Neural regeneration research. vol 17. issue 2. 2021-10-22. PMID:34269182. |
in fact, pgc-1α downregulation in different brain areas (hippocampus, substantia nigra, cortex, striatum and spinal cord) that occurs in function of neurological damage including oxidative stress, neuronal loss, and motor disorders has been seen in several animal and cellular models of neurodegenerative diseases. |
2021-10-22 |
2023-08-13 |
mouse |
| Feng Zhou, Xian Wang, Baoyu Han, Xiaohui Tang, Ru Liu, Qing Ji, Zhiqiang Zhou, Lidong Zhan. Short-chain fatty acids contribute to neuropathic pain via regulating microglia activation and polarization. Molecular pain. vol 17. 2021-10-14. PMID:33626986. |
the levels of microglia markers including ionized calcium-binding adaptor molecule 1 (iba1), cluster of differentiation 11b (cd11b), pro-inflammatory phenotype markers including cd68, interleukin-1β (il-1β), tumor necrosis factor-α (tnf-α), and anti-inflammatory phenotype markers including cd206, il-4 in the hippocampus and spinal cord were determined on day 21 after cci. |
2021-10-14 |
2023-08-13 |
mouse |