| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Stefano Cataldi, Clay Lacefield, Shashaank N, Gautam Kumar, Siham Boumhaouad, David Sulze. Decreased dorsomedial striatum direct pathway neuronal activity is required for learned motor coordination. eNeuro. 2022-09-28. PMID:36171055. |
it has been suggested that the dorsomedial striatum (dms) is engaged in the early stages of motor learning for goal-directed actions, whereas at later stages, control is transferred to the dorsolateral striatum (dls), a process that enables learned motor actions to become a skill or habit. |
2022-09-28 |
2023-08-14 |
mouse |
| Jaec A Emtage, Megan L Shipman, Laura H Corbi. The role of dorsomedial striatum adenosine 2A receptors in the loss of goal-directed behaviour. Psychopharmacology. 2022-09-21. PMID:36129491. |
the role of dorsomedial striatum adenosine 2a receptors in the loss of goal-directed behaviour. |
2022-09-21 |
2023-08-14 |
Not clear |
| Priscilla Ambrosi, Talia N Lerne. Striatonigrostriatal circuit architecture for disinhibition of dopamine signaling. Cell reports. vol 40. issue 7. 2022-08-17. PMID:35977498. |
the basal ganglia operate largely in closed parallel loops, including an associative circuit for goal-directed behavior originating from the dorsomedial striatum (dms) and a somatosensory circuit important for habit formation originating from the dorsolateral striatum (dls). |
2022-08-17 |
2023-08-14 |
Not clear |
| Sanghoon Choi, Yijuan Du, David L Wokosin, Steven M Grave. Acute and protracted abstinence from methamphetamine bidirectionally changes intrinsic excitability of indirect pathway spiny projection neurons in the dorsomedial striatum. Scientific reports. vol 12. issue 1. 2022-07-15. PMID:35840639. |
the dorsal striatum can be subdivided into the dorsomedial (dms) and dorsolateral (dls) striatum with the dms implicated in goal-directed and dls in habitual behaviors; both regions are primarily composed of gabaergic direct (dspns) and indirect pathway (ispns) spiny projection neurons. |
2022-07-15 |
2023-08-14 |
mouse |
| Qiang Shan, Xiaoxuan Yu, Yao Tia. Adolescent social isolation shifts the balance of decision-making strategy from goal-directed action to habitual response in adulthood via suppressing the excitatory neurotransmission onto the direct pathway of the dorsomedial striatum. Cerebral cortex (New York, N.Y. : 1991). 2022-05-07. PMID:35524719. |
adolescent social isolation shifts the balance of decision-making strategy from goal-directed action to habitual response in adulthood via suppressing the excitatory neurotransmission onto the direct pathway of the dorsomedial striatum. |
2022-05-07 |
2023-08-13 |
Not clear |
| Qiang Shan, Xiaoxuan Yu, Yao Tia. Adolescent social isolation shifts the balance of decision-making strategy from goal-directed action to habitual response in adulthood via suppressing the excitatory neurotransmission onto the direct pathway of the dorsomedial striatum. Cerebral cortex (New York, N.Y. : 1991). 2022-05-07. PMID:35524719. |
this study has further revealed that adolescent social isolation induces a suppression in the excitatory neurotransmission onto the direct-pathway medium spiny neurons of the dorsomedial striatum (dms), and that chemogenetically compensating this suppression effect shifts the balance of decision-making strategy from habitual response back to goal-directed action. |
2022-05-07 |
2023-08-13 |
Not clear |
| Tanya Sippy, Corryn Chaimowitz, Sylvain Crochet, Carl C H Peterse. Cell Type-Specific Membrane Potential Changes in Dorsolateral Striatum Accompanying Reward-Based Sensorimotor Learning. Function (Oxford, England). vol 2. issue 6. 2022-03-25. PMID:35330797. |
the striatum integrates sensorimotor and motivational signals, likely playing a key role in reward-based learning of goal-directed behavior. |
2022-03-25 |
2023-08-13 |
mouse |
| Sylvie Perez, Yihui Cui, Gaëtan Vignoud, Elodie Perrin, Alexandre Mendes, Zhiwei Zheng, Jonathan Touboul, Laurent Venanc. Striatum expresses region-specific plasticity consistent with distinct memory abilities. Cell reports. vol 38. issue 11. 2022-03-16. PMID:35294877. |
the striatum mediates two learning modalities: goal-directed behavior in dorsomedial (dms) and habits in dorsolateral (dls) striata. |
2022-03-16 |
2023-08-13 |
Not clear |
| Weixing Shen, Shenyu Zhai, D James Surmeie. Striatal synaptic adaptations in Parkinson's disease. Neurobiology of disease. 2022-03-10. PMID:35272023. |
the striatum is densely innervated by mesencephalic dopaminergic neurons that modulate acquisition and vigor of goal-directed actions and habits. |
2022-03-10 |
2023-08-13 |
mouse |
| Chao Wu, Wei Zheng, Xiaohua Jia, Yonghui Li, Fang Shen, Abbas Haghparast, Jing Liang, Nan Sui, Jian-Jun Zhan. Adolescent chronic unpredictable stress causes a bias in goal-directed behavior and distinctively changes the expression of NMDA and dopamine receptors in the dorsomedial and dorsolateral striatum in male rats. Developmental psychobiology. vol 64. issue 2. 2022-02-22. PMID:35191528. |
adolescent chronic unpredictable stress causes a bias in goal-directed behavior and distinctively changes the expression of nmda and dopamine receptors in the dorsomedial and dorsolateral striatum in male rats. |
2022-02-22 |
2023-08-13 |
rat |
| Dhwani P Sadaphal, Adarsh Kumar, Pratik K Muth. Sensorimotor learning in response to errors in task performance. eNeuro. 2022-02-03. PMID:35110383. |
specifically, behavioral changes following large errors were consistent with goal-directed or model-based control, known to be supported by connections between prefrontal cortex and associative striatum. |
2022-02-03 |
2023-08-13 |
human |
| Megan L Shipman, Laura H Corbi. Diet-induced deficits in goal-directed control are rescued by agonism of group II metabotropic glutamate receptors in the dorsomedial striatum. Translational psychiatry. vol 12. issue 1. 2022-01-29. PMID:35091538. |
diet-induced deficits in goal-directed control are rescued by agonism of group ii metabotropic glutamate receptors in the dorsomedial striatum. |
2022-01-29 |
2023-08-13 |
rat |
| Megan L Shipman, Laura H Corbi. Diet-induced deficits in goal-directed control are rescued by agonism of group II metabotropic glutamate receptors in the dorsomedial striatum. Translational psychiatry. vol 12. issue 1. 2022-01-29. PMID:35091538. |
further, we found that direct infusion of ly379268 into the dorsomedial striatum, a region associated with goal-directed control, also restored goal-directed responding in the obesogenic-diet group. |
2022-01-29 |
2023-08-13 |
rat |
| Youna Vandaele, David J Ottenheimer, Patricia H Jana. Dorsomedial Striatal Activity Tracks Completion of Behavioral Sequences in Rats. eNeuro. vol 8. issue 6. 2021-12-11. PMID:34725103. |
here, we examine how dorsomedial striatum (dms), a region pivotal for forming associations among stimuli, actions, and outcomes, encodes the execution of goal-directed action sequences that require self-monitoring of behavior. |
2021-12-11 |
2023-08-13 |
rat |
| Elizabeth N Holly, M Felicia Davatolhagh, Rodrigo A España, Marc V Fuccill. Striatal low-threshold spiking interneurons locally gate dopamine. Current biology : CB. vol 31. issue 18. 2021-10-31. PMID:34302742. |
the dorsomedial striatum (dms) is a central hub supporting goal-directed learning and motor performance. |
2021-10-31 |
2023-08-13 |
Not clear |
| Sa-Ik Hong, Seungwoo Kang, Matthew Baker, Doo-Sup Cho. Astrocyte-neuron interaction in the dorsal striatum-pallidal circuits and alcohol-seeking behaviors. Neuropharmacology. vol 198. 2021-10-14. PMID:34433087. |
especially, the dorsal striatum can be further divided into the dorsomedial striatum (dms, equivalent to caudate in primates and humans) and dorsolateral striatum (dls, equivalent to putamen), which orchestrates goal-directed and habitual reward-seeking and taking behaviors, respectively. |
2021-10-14 |
2023-08-13 |
Not clear |
| Yan He, Linshan Huang, Ke Wang, Xinran Pan, Qionghui Cai, Feiyang Zhang, Jingjing Yang, Gengjing Fang, Xinyue Zhao, Feng You, Yijia Feng, Yan Li, Jiang-Fan Che. α-Synuclein Selectively Impairs Motor Sequence Learning and Value Sensitivity: Reversal by the Adenosine A2A Receptor Antagonists. Cerebral cortex (New York, N.Y. : 1991). 2021-08-02. PMID:34339491. |
1) contrary to the widely held view of habit-learning deficit in early pd, α-syn aggregates in the dorsomedial striatum (dms) and dorsolateral striatum (dls) did not affect acquisition of habit learning, but selectively impaired goal-directed behavior with reduced value sensitivity. |
2021-08-02 |
2023-08-13 |
Not clear |
| Kari A Johnson, Lucas Voyvodic, Gabriel C Loewinger, Yolanda Mateo, David M Lovinge. Operant self-stimulation of thalamic terminals in the dorsomedial striatum is constrained by metabotropic glutamate receptor 2. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 45. issue 9. 2021-06-23. PMID:31995814. |
we evaluated the reinforcing properties of optogenetic stimulation of thalamostriatal terminals, which are associated with vesicular glutamate transporter 2 (vglut2) expression, in the dorsomedial striatum (dms), a region implicated in goal-directed behaviors. |
2021-06-23 |
2023-08-13 |
mouse |
| Michael S Patton, Morgan Heckman, Cecelia Kim, Chaoqi Mu, Brian N Mathu. Compulsive alcohol consumption is regulated by dorsal striatum fast-spiking interneurons. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 46. issue 2. 2021-06-23. PMID:32663841. |
the dorsomedial and dorsolateral striatum support goal-directed and habitual action strategies, respectively. |
2021-06-23 |
2023-08-13 |
mouse |
| Sa-Ik Hong, Amanda Bullert, Matthew Baker, Doo-Sup Cho. Astrocytic equilibrative nucleoside transporter type 1 upregulations in the dorsomedial and dorsolateral striatum distinctly coordinate goal-directed and habitual ethanol-seeking behaviours in mice. The European journal of neuroscience. vol 52. issue 3. 2021-06-21. PMID:32306482. |
astrocytic equilibrative nucleoside transporter type 1 upregulations in the dorsomedial and dorsolateral striatum distinctly coordinate goal-directed and habitual ethanol-seeking behaviours in mice. |
2021-06-21 |
2023-08-13 |
mouse |