| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Gubidat Alilova, Lyudmila Tikhonova, Carmina Montoliu, Elena Kosenk. Ammoniagenic Action of Valproate without Signs of Hepatic Dysfunction in Rats: Possible Causes and Supporting Evidence. Biomolecules. vol 14. issue 3. 2024-03-28. PMID:38540788. |
the levels of ammonia, urea, aspartate aminotransferase (ast), and alanine aminotransferase (alt) were measured in blood plasma. |
2024-03-28 |
2024-03-30 |
rat |
| Aylin Elkama, Nazlıcan İlik, Mehmet Ak, Bensu Karahali. Are changes in olanzapine-induced liver enzyme levels associated with Arhiv za higijenu rada i toksikologiju. vol 75. issue 1. 2024-03-28. PMID:38548381. |
are changes in olanzapine-induced liver enzyme levels associated with olanzapine treatment sometimes produces transient liver biochemistry abnormalities, and such drug-induced liver injuries are mainly monitored by measuring blood levels of alanine aminotransferase (alt) and aspartate aminotransferase (ast), whereas alpha-glutathione-s-transferase (α-gst) is not routinely measured in clinics, even though it can serve as an earlier and more specific biomarker of liver damage. |
2024-03-28 |
2024-03-31 |
Not clear |
| Mahmoud Yolmeh, Morteza Khomeiri, Ezzatollah Ghaemi, Mehmet Selim Şilbi. Acute toxicity and anti-enterotoxigenic activity of pigment extracted from Micrococcus roseus. Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]. 2024-03-27. PMID:38532186. |
in addition, the acute toxicity of pem was evaluated on albino mice through alkaline phosphatase (alp), aspartate aminotransferas (ast), and alanine aminotransferase (alt) of liver and its histopathological changes. |
2024-03-27 |
2024-03-29 |
mouse |
| Ji Young Lee, Carmen Coombs, Jennifer Clarke, Rachel Berge. AST and ALT Elevation in Suspected Physical Abuse: Can the Threshold to Obtain an Abdominal CT be Raised? The journal of trauma and acute care surgery. 2024-03-26. PMID:38527969. |
current recommendations are to obtain screening liver function tests (lfts) in all children with suspected physical abuse and an abdominal computed tomography (ct) when the aspartate aminotransferase (ast) or alanine aminotransferase (alt) is >80 iu/l. |
2024-03-26 |
2024-03-28 |
Not clear |
| Mengyun Dong, Tianliang Zhang, Xueli Liang, Xinyi Cheng, Fuyan Shi, Hang Yuan, Fengxiang Zhang, Qiqi Jiang, Xia Wan. Sesamin alleviates lipid accumulation induced by oleic acid via PINK1/Parkin-mediated mitophagy in HepG2 cells. Biochemical and biophysical research communications. vol 708. 2024-03-26. PMID:38531220. |
cell viability was evaluated using the cck-8 method, and triglycerides (tg), total cholesterol (tc), high-density lipoprotein cholesterol (hdl-c), low-density lipoprotein, cholesterol (ldl-c), alanine aminotransferase (alt), along with aspartate aminotransferase (ast) were assessed by oil red o staining, transmission electron microscopy (tem), and biochemical kits to investigate the lipid-lowering effects of sesamin. |
2024-03-26 |
2024-03-29 |
Not clear |
| H Kamiyama, C Nonaka, H Saitoh, M Ohno, Y Shimizu, K Isod. Anatase and rutile titanium oxide nanoparticles induce acute kidney injury by coadministration with paraquat, cisplatin or 5-aminosalicylic acid. Die Pharmazie. vol 79. issue 1. 2024-03-21. PMID:38509631. |
as a result, when nta and ntr were administered alone, no increases were observed in aspartate aminotransferase (ast) and alanine aminotransferase (alt), which are indicators of liver damage, or urea nitrogen (bun), which is an indicator of kidney damage. |
2024-03-21 |
2024-03-23 |
mouse |
| Hadir F Eldessouky, Magda Mari. Nonsurgical Treatment of Periodontitis in Menopausal Patients: A Randomized Control Trial. BioMed research international. vol 2024. 2024-03-21. PMID:38510979. |
menopause is typically accompanied by significant systemic and oral manifestations, including hormonal changes and increased susceptibility to periodontal disease, which may involve inflammatory biomarkers like aspartate aminotransferase (ast) and osteocalcin in gingival crevicular fluid (gcf). |
2024-03-21 |
2024-03-23 |
Not clear |
| Shishirendu S Parihar, Aakash S Shah, Nitesh Bassi, Ishan Mittal, Dawesh Yadav, Vinod K Dixit, Anurag K Tiwar. Observational Study of Clinical Profiles and Management of Liver Abscess in Hospitalized Patients: A North Indian Tertiary Care Perspective. Cureus. vol 16. issue 2. 2024-03-20. PMID:38505450. |
laboratory investigations showed leukocytosis in 121 (80.7%), elevated liver enzymes (95 (63.3%) aspartate aminotransferase (ast) and 80 (53.3%) alanine transaminase (alt)), elevated alkaline phosphatase (alp) in 133 (88.7%), and low albumin levels (138 (92%)) in a significant proportion of patients. |
2024-03-20 |
2024-03-23 |
Not clear |
| Nayuta Shimizu, Syuichi Nakai, Takeshi Takahashi, Masahiro Takihata, Kazuhiko Kotan. Prognostic Biomarkers of Mortality in Older Patients Without Cancer in Home Healthcare. Cureus. vol 16. issue 2. 2024-03-19. PMID:38500913. |
generic biomarkers included hemoglobin (hb), albumin (alb), c-reactive protein (crp), estimated glomerular filtration rate (egfr), aspartate aminotransferase (ast), and alanine aminotransferase (alt). |
2024-03-19 |
2024-03-21 |
Not clear |
| Geoffrey H Siwo, Amit G Singal, Akbar K Walje. Pan-cancer molecular signatures connecting aspartate transaminase (AST) to cancer prognosis, metabolic and immune signatures. bioRxiv : the preprint server for biology. 2024-03-18. PMID:38496547. |
pan-cancer molecular signatures connecting aspartate transaminase (ast) to cancer prognosis, metabolic and immune signatures. |
2024-03-18 |
2024-03-20 |
Not clear |
| Shuaijun Li, Caiting Meng, Qian Hao, Ruina Zhou, Luyao Dai, Yucheng Guo, Sitong Zhao, Xin Zhou, Chunju Lou, Ji Xu, Peng Xu, Jinfan Yang, Yifan Ding, Yanni Lv, Shengli Han, Shuai Li, Jing Li, Huafeng Kang, Zhengtao Xiao, Mingqian Tan, Xiaobin Ma, Hao W. "On/off"-switchable crosslinked PTX-nanoformulation with improved precise delivery for NSCLC brain metastases and restrained adverse reaction over nab-PTX. Biomaterials. vol 307. 2024-03-16. PMID:38492523. |
compared to nab-ptx, bpm-pd@ptx demonstrates improved therapeutic efficacy with a reduced tumor area (only 14.6%) and extended survival duration, while mitigating adverse reactions (over 83.7%) in aspartate aminotransferase (ast) and alanine aminotransferase (alt), offering a promising approach for the treatment of nsclc brain metastases. |
2024-03-16 |
2024-03-19 |
Not clear |
| Yaqi Xue, Yang Peng, Litian Zhang, Yi Ba, Gang Jin, Ge Li. Effect of different exercise modalities on nonalcoholic fatty liver disease: a systematic review and network meta-analysis. Scientific reports. vol 14. issue 1. 2024-03-15. PMID:38485714. |
resistance training is the best mode to improve aspartate transaminase (ast) (sucra = 81.7). |
2024-03-15 |
2024-03-17 |
Not clear |
| Yali Xu, Ting Su, Hricha Mishra, Reiko Ando, Yutaka Furutani, Jun Lu, Muyi Cai, Harukazu Suzuki, Wenkui Yu, Xian-Yang Qi. Corn Oligopeptide Alleviates Nonalcoholic Fatty Liver Disease by Regulating the Sirtuin Signaling Pathway. Journal of agricultural and food chemistry. 2024-03-15. PMID:38489847. |
oral administration of cp significantly reduced body weight gain by 2.95%, serum cholesterol by 22.54%, and liver injury, as evidenced by a reduction of 32.19% in serum aspartate aminotransferase (ast) and 49.10% in alanine aminotransferase (alt) levels in mice subjected to a high-fat diet (hfd). |
2024-03-15 |
2024-03-18 |
mouse |
| Muhammad Asghar, Noor Khan, Mahroze Fatima, Murat Arslan, Simon John Davies, Naveed Ul Haqu. Feasibility of replacing fish oil with sunflower oil on the growth, body composition, fatty acid profile, antioxidant activity, stress response, and blood biomarkers of Labeo rohita. PloS one. vol 19. issue 3. 2024-03-14. PMID:38483972. |
globulin (glo) levels decreased significantly (p<0.05), while alanine transaminase (alt) and aspartate transaminase (ast) activity showed nonsignificant increases (p>0.05). |
2024-03-14 |
2024-03-17 |
cat |
| Lidan Zhang, Ge Kuang, Xia Gong, Rui Huang, Zizuo Zhao, Yan Li, Jingyuan Wan, Bin Wan. Piperine attenuates hepatic ischemia/reperfusion injury via suppressing the TLR4 signaling cascade in mice. Transplant immunology. 2024-03-14. PMID:38484898. |
the results showed that plasma aminotransferase (alt), aspartate aminotransferase (ast), hepatocyte apoptosis, oxidative stress, and inflammatory cell infiltration significantly increased in hiri mice. |
2024-03-14 |
2024-03-17 |
mouse |
| Jian Song, Bo-Feng Qin, Jin-Jin Zhang, Qi-Yuan Feng, Guan-Cheng Liu, Gui-Yun Zhao, Hai-Ming Su. Regulation of the Nur77-P2X7r Signaling Pathway by Nodakenin: A Potential Protective Function against Alcoholic Liver Disease. Molecules (Basel, Switzerland). vol 29. issue 5. 2024-03-13. PMID:38474588. |
in vivo, histopathological alterations were markedly alleviated by nk, accompanied by reductions in serum triglyceride (tg), aspartate aminotransferase (ast), and alanine aminotransferase (alt) levels and the modulation of lipin-1, srebp1, and nur77 levels in comparison to the etoh-exposed group ( |
2024-03-13 |
2024-03-15 |
mouse |
| Vítor Macedo Silva, Marta Freitas, Sofia Xavier, Pedro Boal Carvalho, Joana Magalhães, Carla Marinho, José Cotte. The New FibroScan-AST (FAST) Score: Enhancing Diabetes Mellitus Impact on Metabolic-Associated Fatty Liver Disease. GE Portuguese journal of gastroenterology. vol 30. issue 6. 2024-03-13. PMID:38476150. |
in 2020, the fibroscan-ast (fast) score was internationally validated as a new tool able to identify patients with steatohepatitis who benefit the most from further therapies, based on liver transient elastography (lte) findings and serum levels of aspartate aminotransferase (ast). |
2024-03-13 |
2024-03-15 |
Not clear |
| Asmaa Elebishehy, Mohamed M Ahmed, Badr Aldahmash, Mostafa Abdelgaber Mohamed, Aya A Shetaia, Shaden A M Khalifa, Mabrouk Attia Abd Eldaim, Hesham R El-Seedi, Nermeen Yosr. Cymbopogon schoenanthus (L) extract ameliorates high fat diet-induced obesity and dyslipidemia via reducing expression of lipogenic and thermogenic proteins. Fitoterapia. 2024-03-13. PMID:38479618. |
supplementation of hfd significantly increased the body weight, levels of serum triacylglycerol, total cholesterol, very low-density lipoprotein, low density lipo-protein, glucose, serum alanine aminotransferase (alt) and aspartate aminotransferase (ast) activities. |
2024-03-13 |
2024-03-16 |
rat |
| Ayed A Shati, Refaat A Eid, Attalla F El-Kott, Youssef A Alqahtani, Abdullah S Shatoor, Mohamed Samir Ahmed Zak. Curcumin attenuates doxorubicin-induced cardiotoxicity Heliyon. vol 10. issue 5. 2024-03-12. PMID:38468941. |
lipid peroxidation assessed as malondialdehyde (mda), aspartate aminotransferase (ast), alanine aminotransferase (alt), oxidative stress markers as catalase (cat), superoxide dismutase (sod), and inflammatory markers as tumor necrosis factor-alpha (tnf-α) in heart homogenates, each one was assessed. |
2024-03-12 |
2024-03-14 |
rat |
| Karla Falconí, Édgar Zapata-Vívenes, César Lodeiro. Inorganic osmolytes and enzymatic biomarkers from the manabi oyster (Crassostrea cf. corteziensis) in response to saline stress. Marine environmental research. vol 196. 2024-03-10. PMID:38461608. |
aspartate aminotransferase (ast), alanine aminotransferase (alt), lactate dehydrogenase (ldh), alkaline phosphatase (alp) and catalase (cat) activity were analysed. |
2024-03-10 |
2024-03-14 |
cat |