| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xiaojuan Lu, Yixing Song, Jiaqi Wang, Yunyun Cai, Siwan Peng, Jiaqi Lin, Biqin Lai, Junjie Sun, Tianqing Liu, Gang Chen, Lingyan Xin. Developmental dopaminergic signaling modulates neural circuit formation and contributes to autism spectrum disorder (ASD)-related phenotypes. The American journal of pathology. 2024-03-16. PMID:38492733. |
these findings shed light on the mechanisms underlying the link between disrupted developmental dopamine signaling and asd, and they point to the possibility of targeting dopaminergic signaling in early development for asd treatment. |
2024-03-16 |
2024-03-19 |
human |
| Sherilyn Junelle Recinto, Shobina Premachandran, Sriparna Mukherjee, Alexis Allot, Adam MacDonald, Moein Yaqubi, Samantha Gruenheid, Louis-Eric Trudeau, Jo Anne Stratto. Characterizing enteric neurons in dopamine transporter (DAT)-Cre reporter mice reveals dopaminergic subtypes with dual-transmitter content. The European journal of neuroscience. 2024-03-15. PMID:38487941. |
characterizing enteric neurons in dopamine transporter (dat)-cre reporter mice reveals dopaminergic subtypes with dual-transmitter content. |
2024-03-15 |
2024-03-17 |
mouse |
| Wan-Hsuan Chang, Hung-Te Hsu, Chih-Cheng Lin, Li-Mei An, Chien-Hsing Lee, Horng-Huey Ko, Chih-Lung Lin, Yi-Ching L. Linalool, a Fragrance Compound in Plants, Protects Dopaminergic Neurons and Improves Motor Function and Skeletal Muscle Strength in Experimental Models of Parkinson's Disease. International journal of molecular sciences. vol 25. issue 5. 2024-03-13. PMID:38473763. |
parkinson's disease (pd) is a common neurodegenerative disorder characterized by the gradual loss of dopaminergic neurons in the substantia nigra pars compacta (snpc), resulting in reduced dopamine levels in the striatum and eventual onset of motor symptoms. |
2024-03-13 |
2024-03-15 |
Not clear |
| Ayaka Morigami, Ken Sasak. Physiological specialization of the brain in bumble bee castes: Roles of dopamine in mating-related behaviors in female bumble bees. PloS one. vol 19. issue 3. 2024-03-13. PMID:38478476. |
these results suggest that dopamine plays important roles in gyne-specific behavior in bumble bees and has a common dopaminergic function in female eusocial bees. |
2024-03-13 |
2024-03-16 |
bee |
| Kanika Bhardwaj, Neelu Kanwar Rajawat, Nupur Mathu. Development of Alpha-Synuclein protein model against therapeutic aspects of Parkinson's disease. Indian journal of pharmacology. vol 56. issue 1. 2024-03-08. PMID:38454587. |
journal/ijpha/04.03/01363791-202456010-00007/figure1/v/2024-03-07t095025z/r/image-tiff parkinson's disease (pd) is the most common neurodegenerative disease caused by the steady depletion of dopamine in the striatum due to the loss of dopaminergic neurons. |
2024-03-08 |
2024-03-10 |
Not clear |
| Alagudurai Krishnamoorthy, Riddhi Upadhyay, Murugan Sevana. Chrysin for Neurotrophic and Neurotransmitter Balance in Parkinson's Disease. Methods in molecular biology (Clifton, N.J.). vol 2761. 2024-03-01. PMID:38427256. |
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp) has a direct impact on the dopaminergic neurons in the substantia nigra pars compacta (snpc), dopamine in the striatum (st), homovanillic acid (hva), neurotrophic factors of the snpc, and st regions leading to parkinson's disease (pd). |
2024-03-01 |
2024-03-03 |
mouse |
| Florina Madalina Mindru, Andrei-Flavius Radu, Adrian Gheorghe Bumbu, Ada Radu, Simona Gabriela Bunga. Insights into the Medical Evaluation of Ekbom Syndrome: An Overview. International journal of molecular sciences. vol 25. issue 4. 2024-02-24. PMID:38396826. |
its pathophysiological mechanism involves uncertain dopaminergic imbalances and dysfunction in the dopamine transporter system. |
2024-02-24 |
2024-02-26 |
Not clear |
| Lingling Zhang, Hao Yan. Research progress of neural stem cells as a source of dopaminergic neurons for cell therapy in Parkinson's disease. Molecular biology reports. vol 51. issue 1. 2024-02-24. PMID:38400887. |
parkinson's disease (pd) is a neurodegenerative disease, the most characteristic pathological feature is the progressive loss of dopaminergic (da) neurons in the substantia nigra pars compactus (snpc) of the mesencephalon, along with reduced dopamine content in the striatum. |
2024-02-24 |
2024-02-27 |
Not clear |
| Mateusz Toś, Anna Grażyńska, Sofija Antoniuk, Joanna Siud. Impulse Control Disorders in Parkinson's Disease and Atypical Parkinsonian Syndromes-Is There a Difference? Brain sciences. vol 14. issue 2. 2024-02-23. PMID:38391755. |
icds are known non-motor symptoms in parkinson's disease (pd) and are associated primarily with the use of dopaminergic treatment (drt) and especially dopamine agonists (da). |
2024-02-23 |
2024-02-25 |
Not clear |
| Hyun Jun Lee, Darlene Mae Ortiz, Leandro Val Sayson, Mikyung Kim, Jae Hoon Cheong, Hee Jin Ki. Ameliorating effects of Acanthopanax koreanum extract and components on nicotine dependence and withdrawal symptoms. Addiction biology. vol 29. issue 2. 2024-02-21. PMID:38380695. |
in addition, alterations in the dopaminergic and drd1-epac-erk-creb pathways were observed using dopamine elisa and western blotting using mouse brains. |
2024-02-21 |
2024-02-23 |
mouse |
| Hadeel Khamis, Ohad Cohe. Coupled action potential and calcium dynamics underlie robust spontaneous firing in dopaminergic neurons. Physical biology. 2024-02-21. PMID:38382117. |
dopaminergic neurons are specialized cells in the substantia nigra, tasked with dopamine secretion. |
2024-02-21 |
2024-02-24 |
Not clear |
| Renata Sadibolova, Emily K DiMarco, Angela Jiang, Benjamin Maas, Stephen B Tatter, Adrian Laxton, Kenneth T Kishida, Devin B Terhun. Sub-second and multi-second dopamine dynamics underlie variability in human time perception. medRxiv : the preprint server for health sciences. 2024-02-19. PMID:38370629. |
fast, phasic, dopaminergic signals were associated with underestimation of temporal intervals, whereas slower, tonic, decreases in dopamine were associated with poorer temporal precision. |
2024-02-19 |
2024-02-21 |
human |
| Bushra Bashir, Shahbaz Alam, Nikhil Khandale, Devendra Birla, Sukriti Vishwas, Narendra Kumar Pandey, Gaurav Gupta, Keshav Raj Paudel, Harish Dureja, Puneet Kumar, Thakur Gurjeet Singh, Gowthamarajan Kuppusamy, Flavia Zacconi, Terezinha de Jesus Andreoli Pinto, Muralikrishnan Dhanasekaran, Monica Gulati, Kamal Dua, Sachin Kumar Sing. Opening avenues for treatment of neurodegenerative disease using post-biotics: Breakthroughs and bottlenecks in clinical translation. Ageing research reviews. 2024-02-18. PMID:38369026. |
post-biotic is believed to mediate its neuroprotection by elevating the level of dopamine and reducing the level of α-synuclein in substantia nigra, protecting the loss of dopaminergic neurons, reducing the aggregation of nft, reducing the deposition of amyloid β peptide plagues and ameliorating motor deficits. |
2024-02-18 |
2024-02-21 |
human |
| Qing He, Shuzhen Zhang, Jian Wang, Tengfei Ma, Ding Ma, Li Wu, Mengxi Zhou, Lei Zhao, Yajing Chen, Jianren Liu, Wei Che. The Synergistic Effect Study of Lipopolysaccharide (LPS) and A53T-α-Synuclein: Intranasal LPS Exposure on the A53T-α-Synuclein Transgenic Mouse Model of Parkinson's Disease. Molecular neurobiology. 2024-02-17. PMID:38367134. |
according to our results, after intranasal administration of lps, a53t-α-syn mice showed severe progressive anosmia, hypokinesia, selective dopaminergic (daergic) neuronal losses, decreased striatal dopamine (da) level, and enhanced α-synuclein accumulation within the substantia nigra (sn) in an age-dependent way. |
2024-02-17 |
2024-02-20 |
mouse |
| Xóchitl Flores-Ponce, Adolfo López-Ornelas, Itzel Escobedo-Avila, Mayela Rodríguez-Violante, David Dávila-Ortiz de Montellano, Amín Cervantes-Arriaga, Nancy Monroy-Jaramillo, Aurelio Campos-Romo, Iván Velasc. Establishment of induced pluripotent stem cell lines derived from Parkinson's disease Mexican patients: A sporadic (UNAMi002-A) and a familial (UNAMi003-A) case carrying a mutation in PINK1. Stem cell research. vol 76. 2024-02-15. PMID:38359473. |
parkinson's disease (pd) is characterized by the progressive loss of dopaminergic neurons in the substantia nigra pars compacta, which results in a prominent reduction of striatal dopamine levels leading to motor alterations. |
2024-02-15 |
2024-02-18 |
Not clear |
| Muneshwar Mehra, Gerardo Molina, Md Tarikul Islam, Zahra M Dhanerawala, Eleonora Bano, Edward B Ha. Functionally distinct dopamine domains in the hippocampus. bioRxiv : the preprint server for biology. 2024-02-14. PMID:38352351. |
finally, the subcellular scale of dopamine domains suggests specialized postsynaptic pathways for processing and integrating functionally distinct dopaminergic influences. |
2024-02-14 |
2024-02-16 |
mouse |
| Josep Carbonell-Roig, Alina Aaltonen, Veronica Cartocci, Avery McGuirt, Eugene Mosharov, Jan Kehr, Ori J Lieberman, David Sulzer, Anders Borgkvist, Emanuela Santin. Dysregulated acetylcholine-mediated dopamine neurotransmission in the eIF4E Tg mouse model of autism spectrum disorders. bioRxiv : the preprint server for biology. 2024-02-14. PMID:38352367. |
the loss of normal dopamine neurotransmission is due to a defective nicotinic receptor signaling that regulates calcium dynamics in dopaminergic axons. |
2024-02-14 |
2024-02-16 |
mouse |
| Pingping Song, Dimitri Krain. Protocol to investigate Parkinson's patient-derived dopaminergic neurons by live-cell microscopy and oxidized dopamine assays. STAR protocols. vol 5. issue 1. 2024-02-11. PMID:38341851. |
protocol to investigate parkinson's patient-derived dopaminergic neurons by live-cell microscopy and oxidized dopamine assays. |
2024-02-11 |
2024-02-14 |
human |
| Victor Blokhin, Ekaterina N Pavlova, Elena A Katunina, Marina R Nodel, Galina V Kataeva, Elina R Moskalets, Tatiana S Pronina, Michael V Ugrumo. Dopamine Synthesis in the Nigrostriatal Dopaminergic System in Patients at Risk of Developing Parkinson's Disease at the Prodromal Stage. Journal of clinical medicine. vol 13. issue 3. 2024-02-10. PMID:38337569. |
dopamine synthesis in the nigrostriatal dopaminergic system in patients at risk of developing parkinson's disease at the prodromal stage. |
2024-02-10 |
2024-02-12 |
Not clear |
| Miguel Siqueira Campos Junior, Andréia Gomes Bezerra, Daniela Fernández Curado, Renata Pauluci Gregório, José Carlos Fernandes Galduró. Preliminary investigation of the administration of biperiden to reduce relapses in individuals with cocaine/crack user disorder: A randomized controlled clinical trial. Pharmacology, biochemistry, and behavior. 2024-02-10. PMID:38340989. |
several studies have demonstrated that ach modulates the dopaminergic circuit in the nucleus accumbens, and its blockade appears to be associated with the inhibition of the reinforced effect or the increase in dopamine caused by cocaine use. |
2024-02-10 |
2024-02-14 |
Not clear |