| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| K F Funk, K H Westerman. Influence of lesion of the median raphe nucleus on motility and dopamine turnover. Polish journal of pharmacology and pharmacy. vol 31. issue 4. 1980-03-17. PMID:574958. |
after unilateral microinjection of dopamine into dopaminergic areas intensity of rotation and dominance of direction are amplified in lesioned animals. |
1980-03-17 |
2023-08-11 |
Not clear |
| S I Zharikov, A D Zharikova, A Iu Budantse. [Effect of beta-phenylethylamine on the dopaminergic system of rat brain]. Neirofiziologiia = Neurophysiology. vol 11. issue 6. 1980-02-28. PMID:514416. |
using a quantitative fluorescence-histochemical analysis the dynamics of changes of the dopamine level in dopaminergic neurons of the nigro-neostriatal and mesolimbic systems of the rat brain was studied during an hour after intraperitoneal injection of beta-phenylethylamine (100 mg/kg). |
1980-02-28 |
2023-08-11 |
rat |
| G A Lopez, F D Romano, V A Aletich, L M Lissuzz. Cyclic adenosine 3':5-monophosphate mediation of the effect of dopamine on renin release by renal cortical slices from sodium-deficient rats: modification by dopaminergic and beta-adrenergic receptor blockade. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). vol 162. issue 3. 1980-02-26. PMID:42078. |
cyclic adenosine 3':5-monophosphate mediation of the effect of dopamine on renin release by renal cortical slices from sodium-deficient rats: modification by dopaminergic and beta-adrenergic receptor blockade. |
1980-02-26 |
2023-08-11 |
rat |
| J L Waddington, T J Cro. Rotational responses to serotonergic and dopaminergic agonists after unilateral dihydroxytryptamine lesions of the medial forebrain bundle: co-operative interactions of serotonin and dopamine in neostriatum. Life sciences. vol 25. issue 15. 1980-02-26. PMID:316093. |
rotational responses to serotonergic and dopaminergic agonists after unilateral dihydroxytryptamine lesions of the medial forebrain bundle: co-operative interactions of serotonin and dopamine in neostriatum. |
1980-02-26 |
2023-08-11 |
Not clear |
| W S Evans, A D Rogol, R M MacLeod, M O Thorne. Dopaminergic mechanisms and luteinizing hormone secretion. I. Acute administration of the dopamine agonist bromocriptine does not inhibit luteinizing hormone release in hyperprolactinemic women. The Journal of clinical endocrinology and metabolism. vol 50. issue 1. 1980-02-26. PMID:7188612. |
since hyperprolactinemia is associated with increased hypothalamic dopamine turnover (which may reflect increased dopaminergic activity), inhibition of gnrh by dopamine in this situation would be maximal. |
1980-02-26 |
2023-08-12 |
Not clear |
| K Andersson, R Schwarcz, K Fux. Compensatory bilateral changes in dopamine turnover after striatal kainate lesion. Nature. vol 283. issue 5742. 1980-02-26. PMID:7188627. |
unilateral pharmacological manipulations result in short-term changes in contralateral dopamine (da) release, and surgical lesions on one side lead to long-term alterations in the firing rate of contralateral dopaminergic neurones. |
1980-02-26 |
2023-08-12 |
Not clear |
| M Filio. Effects of interruption of the nigrostriatal pathway and of dopaminergic agents on the spontaneous activity of globus pallidus neurons in the awake monkey. Brain research. vol 178. issue 2-3. 1980-02-15. PMID:116713. |
two lines of evidence strongly suggest that the bursting pallidal activities are a consequence of the interruption of the nigrostriatal dopaminergic pathway: (1) the percentage of bursting pallidal neurons is proportional to the amount of degeneration in the pars compacta of the ipsilateral substantia nigra; (2) chronic administration of dopamine antagonists, haloperidol and reserpine, reproduces in intact monkeys the bursting activities observed in lesioned animals. |
1980-02-15 |
2023-08-11 |
monkey |
| T Di Paolo, R Carmichael, F Labrie, J P Raynau. Effects of estrogens on the characteristics of [3H]spiroperidol and [3H]RU24213 binding in rat anterior pituitary gland and brain. Molecular and cellular endocrinology. vol 16. issue 2. 1980-02-15. PMID:116893. |
since estrogens have been found to exert a marked inhibitory effect on dopaminergic action at the anterior pituitary and striatal levels in the rat, the effect of estrogen treatment has been studied on the binding characteristics of the dopamine (da) antagonist [3h]spiroperidol and of the new da agonist [3h]n-n-propyl-n-phenylethyl-beta-(3-hydroxyphenyl)ethylamine hydrochloride ([3h]ru24213) in rat striatum, nucleus accumbens + olfactory tubercle, frontal cortex and anterior pituitary gland. |
1980-02-15 |
2023-08-11 |
rat |
| G Langer, E J Sachar, R S Nathan, M A Tabrizi, J M Perel, F S Halper. Dopaminergic factors in human prolactin regulation: a pituitary model for the study of a neuroendocrine system in man. Psychopharmacology. vol 65. issue 2. 1980-02-15. PMID:117485. |
a dose of dopamine in the order of 15-60 microgram/min appeared to match the "loss" of endogenous dopaminergic inhibition due to the antidopaminergic effect of the neuroleptic drug. |
1980-02-15 |
2023-08-11 |
human |
| S Bischoff, B Scatton, J Kor. Dopamine metabolism, spiperone binding and adenylate cyclase activity in the adult rat hippocampus after ingrowth of dopaminergic neurones from embryonic implants. Brain research. vol 179. issue 1. 1980-02-15. PMID:509234. |
dopamine metabolism, spiperone binding and adenylate cyclase activity in the adult rat hippocampus after ingrowth of dopaminergic neurones from embryonic implants. |
1980-02-15 |
2023-08-11 |
rat |
| L L Brown, M H Markman, L I Wolfson, B Dvorkin, C Warner, R Katzma. A direct role of dopamine in the rat subthalamic nucleus and an adjacent intrapeduncular area. Science (New York, N.Y.). vol 206. issue 4425. 1980-01-28. PMID:505015. |
thus, neuronal function in this region is directly affected by dopamine and dopaminergic drugs. |
1980-01-28 |
2023-08-11 |
rat |
| S Dessaigne, A M Scotto, M Guigue. [Lithium modifications of the cataleptogenic properties of various neuroleptic drugs in the rat]. Comptes rendus des seances de la Societe de biologie et de ses filiales. vol 172. issue 6. 1980-01-24. PMID:40676. |
licl would interfere at enzymatic level with dopaminergic transmission either by inhibiting activity of cerebral adenylcyclase (unique injection) or by inhibiting dopamine synthesis (repeated injections). |
1980-01-24 |
2023-08-11 |
rat |
| J Vardi, S Flechter, Z Oberman, M Allelov, J M Rabey, M Hertzberg, M Streifle. Plasma dopamine beta hydroxylase (D.B.H.) activity in Parkinsonian patients under L-dopa, and 2-bromo-alpha-ergocriptine loading. Journal of neural transmission. vol 46. issue 1. 1980-01-24. PMID:501350. |
the reduced d.b.h.-activity after treatment with 2-bromo-alpha-ergocriptine may be explained by a pronounced antagonistic influence of 2-bromo-alpha-ergocriptine on the presynaptic dopamine receptors, suggesting that presynaptic dopaminergic receptors are involved in parkinson's disease. |
1980-01-24 |
2023-08-11 |
Not clear |
| G Magelund, J Gerlach, D E Case. Neuroleptic-potentiating effect of alpha-methyl-p-tyrosine compared with haloperidol and placebo in a double-blind cross-over trial. Acta psychiatrica Scandinavica. vol 60. issue 2. 1980-01-19. PMID:41413. |
the hypothesis that schizophrenia results from overactive dopaminergic influences suggests that reducing dopamine synthesis may increase the clinical effects of dopamine receptor blocking neuroleptic drugs. |
1980-01-19 |
2023-08-11 |
Not clear |
| J McCulloch, H E Savaki, M C McCulloch, L Sokolof. Specific distribution of metabolic alterations in cerebral cortex following apomorphine administration. Nature. vol 282. issue 5736. 1980-01-19. PMID:503202. |
moreover, biochemical examinations of processes generally considered to be indicative of dopaminergic neuro-transmission--neuronal uptake of labelled dopamine or dopamine-activation of adenylate cyclase activity--have confirmed a highly restricted locus of action of dopaminergic systems in the cerebral cortex. |
1980-01-19 |
2023-08-11 |
rat |
| M Palkovits, L Záborszky, M J Brownstein, M I Fekete, J P Herman, B Kanyicsk. Distribution of norepinephrine and dopamine in cerebral cortical areas of the rat. Brain research bulletin. vol 4. issue 5. 1979-12-29. PMID:487214. |
the highest dopamine concentration (2,4 ng/mg protein) was measured in the rostral pyriform cortex but other mesocortical (cingulate, frontal, insular and entorhinal) dopaminergic areas also contained relatively high amounts. |
1979-12-29 |
2023-08-11 |
rat |
| F Peillon, F Cesselin, D Bression, N Zygelman, A M Brandi, A Nousbaum, A Mauborgn. In vitro effect of dopamine and L-dopa on prolactin and growth hormone release from human pituitary adenomas. The Journal of clinical endocrinology and metabolism. vol 49. issue 5. 1979-12-29. PMID:489713. |
to determine the site of action of dopaminergic drugs on human prl and gh release from pituitary adenomas, five prl-and five gh-secreting adenomas were incubated with and without dopamine and l-dopa. |
1979-12-29 |
2023-08-11 |
human |
| F Peillon, F Cesselin, D Bression, N Zygelman, A M Brandi, A Nousbaum, A Mauborgn. In vitro effect of dopamine and L-dopa on prolactin and growth hormone release from human pituitary adenomas. The Journal of clinical endocrinology and metabolism. vol 49. issue 5. 1979-12-29. PMID:489713. |
3) the paradoxical effect of dopaminergic drugs on gh secretion in acromegalic patients may be attributed to modified dopamine membrane receptors. |
1979-12-29 |
2023-08-11 |
human |
| G U Corsini, M Del Zompo, M P Piccardi, A Mangoni, G L Gess. Apomorphine as a preferential stimulant of self-inhibitory dopamine receptors in man. Annali dell'Istituto superiore di sanita. vol 14. issue 1. 1979-12-29. PMID:756167. |
these responses therefore are mediated through a stimulation of dopamine receptors leading to a decreased dopaminergic transmission. |
1979-12-29 |
2023-08-11 |
Not clear |
| P W Erhardt, R J Gorczynski, W G Anderso. Conformational analogues of dopamine. Synthesis and pharmacological activity of (E)- and (Z)-2-(3,4-dihydroxyphenyl)cyclopropylamine hydrochlorides. Journal of medicinal chemistry. vol 22. issue 8. 1979-12-18. PMID:40027. |
although neither of the compounds possessed dopaminergic activity in the canine renal blood-flow model, both agents were weak alpha-adrenergic agonists and exhibited cardiostimulatory properties similar to dopamine. |
1979-12-18 |
2023-08-11 |
Not clear |