| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| SeungJu Jackie Oh, Xiaoduo Fa. The Possible Role of the Angiotensin System in the Pathophysiology of Schizophrenia: Implications for Pharmacotherapy. CNS drugs. vol 33. issue 6. 2020-08-28. PMID:30993607. |
in this review, we examine how the central ras affects inflammation, glutamate, dopamine, gamma-aminobutyric acid (gaba), and peroxisome proliferator-activated receptor (ppar)-γ, all of which are associated with schizophrenia etiology. |
2020-08-28 |
2023-08-13 |
Not clear |
| SeungJu Jackie Oh, Xiaoduo Fa. The Possible Role of the Angiotensin System in the Pathophysiology of Schizophrenia: Implications for Pharmacotherapy. CNS drugs. vol 33. issue 6. 2020-08-28. PMID:30993607. |
with a greater understanding of how ras inhibition directly modulates neurotransmitter balance in the brain, it is possible that compounds with ras-inhibiting properties could be used to optimize physiological levels of glutamate, dopamine, and gaba, and the balance among the three neurotransmitters, analogously to how antipsychotic medications mediate the dopaminergic pathways. |
2020-08-28 |
2023-08-13 |
Not clear |
| Marina Rodríguez-Sánchez, Rodrigo Erick Escartín-Pérez, Gerardo Leyva-Gómez, José Arturo Avalos-Fuentes, Francisco Javier Paz-Bermúdez, Santiago Iván Loya-López, Jorge Aceves, David Erlij, Hernán Cortés, Benjamín Florá. Blockade of Intranigral and Systemic D3 Receptors Stimulates Motor Activity in the Rat Promoting a Reciprocal Interaction among Glutamate, Dopamine, and GABA. Biomolecules. vol 9. issue 10. 2020-08-12. PMID:31547016. |
concomitant blockade of d3r with d1r by perfusion of sch 23390 reduced the increase of glutamate; prevented the increment of gaba, but not of dopamine; and abolished behavioral effects. |
2020-08-12 |
2023-08-13 |
rat |
| Jocelyn M Breton, Annabelle R Charbit, Benjamin J Snyder, Peter T K Fong, Elayne V Dias, Patricia Himmels, Hagar Lock, Elyssa B Margoli. Relative contributions and mapping of ventral tegmental area dopamine and GABA neurons by projection target in the rat. The Journal of comparative neurology. vol 527. issue 5. 2020-07-28. PMID:30393861. |
the ventral tegmental area (vta) is a heterogeneous midbrain structure that contains dopamine (da), gaba, and glutamate neurons that project to many different brain regions. |
2020-07-28 |
2023-08-13 |
rat |
| Alicia J Avelar, Austin T Akers, Zachary J Baumgard, Skylar Y Cooper, Gabriella P Casinelli, Brandon J Henderso. Why flavored vape products may be attractive: Green apple tobacco flavor elicits reward-related behavior, upregulates nAChRs on VTA dopamine neurons, and alters midbrain dopamine and GABA neuron function. Neuropharmacology. vol 158. 2020-07-20. PMID:31369741. |
why flavored vape products may be attractive: green apple tobacco flavor elicits reward-related behavior, upregulates nachrs on vta dopamine neurons, and alters midbrain dopamine and gaba neuron function. |
2020-07-20 |
2023-08-13 |
mouse |
| Alicia J Avelar, Austin T Akers, Zachary J Baumgard, Skylar Y Cooper, Gabriella P Casinelli, Brandon J Henderso. Why flavored vape products may be attractive: Green apple tobacco flavor elicits reward-related behavior, upregulates nAChRs on VTA dopamine neurons, and alters midbrain dopamine and GABA neuron function. Neuropharmacology. vol 158. 2020-07-20. PMID:31369741. |
our electrophysiological assays with male mice revealed that farnesol treatment increases ventral tegmental area (vta) dopamine neuron firing frequency and this may be due to a decrease in inhibitory tone from gaba neurons. |
2020-07-20 |
2023-08-13 |
mouse |
| Mohammad-Reza Zarrindast, Fatemeh Khakpa. The modulatory role of nicotine on cognitive and non-cognitive functions. Brain research. vol 1710. 2020-06-25. PMID:30529105. |
furthermore, the effect of nicotine in modulation of cognitive and non-cognitive functions can produce by other neurochemical systems such as opioid, dopamine, glutamate, cannabinoids, gaba and serotonin as well as nitric oxide. |
2020-06-25 |
2023-08-13 |
Not clear |
| Zhi-Long Zhang, Yu-Gang Gao, Pu Zang, Pei-Pei Gu, Yan Zhao, Zhong-Mei He, Hong-Yan Zh. [Research progress on mechanism of gastrodin and p-hydroxybenzyl alcohol on central nervous system]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 45. issue 2. 2020-06-23. PMID:32237313. |
they alleviate hippocampal neuronal toxicity mainly by regulating a variety of neurotransmitters, such as acetylcholine, glutamic acid(glu), γ-aminobutyric acid(gaba), serotonin(5-ht), dopamine(da), norepinephrine(ne), 5-indoleacetic acid(5-hiaa), high vanillic acid(hva) and dihydroxyphenylacetic acid(dopac), pro-inflammatory cell growth factors, such as il-1β, il-6 and tnf-α and relevant receptor functions, and exert neuropharmacological effects by effectively increasing mrna expressions of brain neurotrophic factors, such as bdnf and gdnf, and further inhibiting the apoptosis of damaged neurons. |
2020-06-23 |
2023-08-13 |
Not clear |
| Luana Martins de Carvalho, Juliana Lauar Gonçalves, Agatha Sondertoft Braga Pedersen, Samara Damasceno, Renato Elias Moreira Júnior, Tatiani Uceli Maioli, Ana Maria Caetano de Faria, Ana Lúcia Brunialti Godar. High-fat diet withdrawal modifies alcohol preference and transcription of dopaminergic and GABAergic receptors. Journal of neurogenetics. vol 33. issue 1. 2020-06-22. PMID:30516420. |
the result obtained with this model point out that the relation among high-fat diet consumption and alcohol intake appears to depend on the presence or absence of the diet when alcohol intake is evaluated, and that an imbalance in the mesocorticolimbic dopaminergic pathway, observed by the transcriptional regulation of the dopamine receptors (drd1/drd2) and gaba |
2020-06-22 |
2023-08-13 |
human |
| Motohiro Okada, Kouji Fukuyama, Yasuhiro Kawano, Takashi Shiroyama, Dai Suzuki, Yuto Ued. Effects of acute and sub-chronic administrations of guanfacine on catecholaminergic transmissions in the orbitofrontal cortex. Neuropharmacology. vol 156. 2020-06-10. PMID:30802458. |
acute lc local and sub-chronic systemic administrations of guanfacine reduced norepinephrine release in lc, ofc and rtn, and also reduced gaba release in mdtn, whereas ampa-induced (perfusion with ampa into ndtn) releases of l-glutamate, norepinephrine and dopamine in ofc were enhanced by sub-chronic systemic guanfacine administration. |
2020-06-10 |
2023-08-13 |
Not clear |
| M A Al Kahtan. Effect of both selenium and biosynthesized nanoselenium particles on cadmium-induced neurotoxicity in albino rats. Human & experimental toxicology. vol 39. issue 2. 2020-06-02. PMID:31619074. |
it also affects cholinergic, glutamatergic, gamma-aminobutyric acid (gabaergic), dopamine, serotonin and acetylcholine neurotransmitters in brain tissue. |
2020-06-02 |
2023-08-13 |
rat |
| Chloé Bouarab, Brittney Thompson, Abigail M Polte. VTA GABA Neurons at the Interface of Stress and Reward. Frontiers in neural circuits. vol 13. 2020-05-25. PMID:31866835. |
however, the vta is not only made of dopamine (da) cells, as approximately 30% of cells in the vta are gaba neurons. |
2020-05-25 |
2023-08-13 |
Not clear |
| Taryn E Grieder, Morgane Besson, Geith Maal-Bared, Stéphanie Pons, Uwe Maskos, Derek van der Koo. β2* nAChRs on VTA dopamine and GABA neurons separately mediate nicotine aversion and reward. Proceedings of the National Academy of Sciences of the United States of America. vol 116. issue 51. 2020-04-01. PMID:31776253. |
β2* nachrs on vta dopamine and gaba neurons separately mediate nicotine aversion and reward. |
2020-04-01 |
2023-08-13 |
Not clear |
| Taryn E Grieder, Morgane Besson, Geith Maal-Bared, Stéphanie Pons, Uwe Maskos, Derek van der Koo. β2* nAChRs on VTA dopamine and GABA neurons separately mediate nicotine aversion and reward. Proceedings of the National Academy of Sciences of the United States of America. vol 116. issue 51. 2020-04-01. PMID:31776253. |
we selectively reexpressed β2* nachrs in vta dopamine or vta γ-amino-butyric acid (gaba) neurons in β2 |
2020-04-01 |
2023-08-13 |
Not clear |
| Rao Fu, Wanhong Zuo, Nimisha Shiwalkar, Qinghua Mei, Qing Fan, Xuejun Chen, Jing Li, Alex Bekker, Jiang-Hong Y. Alcohol withdrawal drives depressive behaviors by activating neurons in the rostromedial tegmental nucleus. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 44. issue 8. 2020-03-31. PMID:30928995. |
rostromedial tegmental nucleus (rmtg) gaba neurons exert a primary inhibitory drive onto midbrain dopamine neurons and are excited by a variety of aversive stimuli. |
2020-03-31 |
2023-08-13 |
rat |
| Rao Fu, Wanhong Zuo, Nimisha Shiwalkar, Qinghua Mei, Qing Fan, Xuejun Chen, Jing Li, Alex Bekker, Jiang-Hong Y. Alcohol withdrawal drives depressive behaviors by activating neurons in the rostromedial tegmental nucleus. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 44. issue 8. 2020-03-31. PMID:30928995. |
ex vivo electrophysiological data showed that chemogenetic inactivation of rmtg neurons reduced gaba release and accelerated spontaneous firings of vta dopamine neurons. |
2020-03-31 |
2023-08-13 |
rat |
| Yukitoshi Izumi, Charles F Zorumsk. Temperoammonic Stimulation Depotentiates Schaffer Collateral LTP via p38 MAPK Downstream of Adenosine A1 Receptors. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 39. issue 10. 2020-03-23. PMID:30622168. |
we previously found that low-frequency stimulation of direct temperoammonic (ta) inputs to hippocampal area ca1 depotentiates previously established long-term potentiation in the schaffer collateral (sc) pathway through complex signaling involving dopamine, endocannabinoids, neuregulin-1, gaba, and adenosine, with adenosine being the most distal modulator identified to date. |
2020-03-23 |
2023-08-13 |
rat |
| Amy I Smith-Dijak, Marja D Sepers, Lynn A Raymon. Alterations in synaptic function and plasticity in Huntington disease. Journal of neurochemistry. vol 150. issue 4. 2020-03-18. PMID:31095731. |
this includes classical neurotransmitters like glutamate and gamma-aminobutyric acid, modulators such as dopamine, adenosine and endocannabinoids, and molecules like brain-derived neurotrophic factor which affect neurotransmission in a more indirect manner. |
2020-03-18 |
2023-08-13 |
Not clear |
| Wanhao Chi, Atulya S R Iyengar, Monique Albersen, Marjolein Bosma, Nanda M Verhoeven-Duif, Chun-Fang Wu, Xiaoxi Zhuan. Pyridox (am) ine 5'-phosphate oxidase deficiency induces seizures in Drosophila melanogaster. Human molecular genetics. vol 28. issue 18. 2020-03-09. PMID:31261385. |
pyridox (am) ine 5'-phosphate oxidase (pnpo) is a rate-limiting enzyme in converting dietary vitamin b6 (vb6) to pyridoxal 5'-phosphate (plp), the biologically active form of vb6 and involved in the synthesis of neurotransmitters including γ-aminobutyric acid (gaba), dopamine, and serotonin. |
2020-03-09 |
2023-08-13 |
human |
| Niels R Ntamati, Meaghan Creed, Ridouane Achargui, Christian Lüsche. Correction: Periaqueductal efferents to dopamine and GABA neurons of the VTA. PloS one. vol 14. issue 7. 2020-02-25. PMID:31269079. |
correction: periaqueductal efferents to dopamine and gaba neurons of the vta. |
2020-02-25 |
2023-08-13 |
Not clear |