| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Riccardo Dore, Regina Krotenko, Jan Philipp Reising, Luca Murru, Sivaraj Mohana Sundaram, Alessandro Di Spiezio, Helge Müller-Fielitz, Markus Schwaninger, Olaf Jöhren, Jens Mittag, Maria Passafaro, Marya Shanabrough, Tamas L Horvath, Carla Schulz, Hendrik Lehner. Nesfatin-1 decreases the motivational and rewarding value of food. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 45. issue 10. 2021-06-23. PMID:32353862. |
ex vivo electrophysiological recordings show that nesfatin-1 hyperpolarizes dopamine, but not gaba, neurons of the vta by inducing an outward potassium current. |
2021-06-23 |
2023-08-13 |
Not clear |
| Salar Vaseghi, Mohammad Nasehi, Mohammad-Reza Zarrindas. How do stupendous cannabinoids modulate memory processing via affecting neurotransmitter systems? Neuroscience and biobehavioral reviews. vol 120. 2021-06-21. PMID:33171142. |
in the present study, we wanted to review the role of cannabinoids in learning and memory in animal models, with respect to their interaction effects with six principal neurotransmitters involved in learning and memory including dopamine, glutamate, gaba (γ-aminobutyric acid), serotonin, acetylcholine, and noradrenaline. |
2021-06-21 |
2023-08-13 |
Not clear |
| Peng Wang, Xiaoxia Gao, Fang Zhao, Yao Gao, Kexin Wang, Jun-Sheng Tian, Zhenyu Li, Xue-Mei Qi. Study of the Neurotransmitter Changes Adjusted by Circadian Rhythm in Depression Based on Liver Transcriptomics and Correlation Analysis. ACS chemical neuroscience. vol 12. issue 12. 2021-06-21. PMID:34060807. |
compared with the control group, the levels of neurotransmitters including 5-hydroxytryptamine (5-ht), acetylcholine, glutamate (glu), and dopamine (da) in the hippocampus and 5-ht, norepinephrine, γ-aminobutyric acid (gaba), and 5-hydroxyindoleacetic acid in serum were significantly changed in the cums rats. |
2021-06-21 |
2023-08-13 |
rat |
| Austin T Akers, Skylar Y Cooper, Zachary J Baumgard, Gabriella P Casinelli, Alicia J Avelar, Brandon J Henderso. Upregulation of nAChRs and Changes in Excitability on VTA Dopamine and GABA Neurons Correlates to Changes in Nicotine-Reward-Related Behavior. eNeuro. vol 7. issue 5. 2021-06-18. PMID:32988984. |
upregulation of nachrs and changes in excitability on vta dopamine and gaba neurons correlates to changes in nicotine-reward-related behavior. |
2021-06-18 |
2023-08-13 |
mouse |
| Austin T Akers, Skylar Y Cooper, Zachary J Baumgard, Gabriella P Casinelli, Alicia J Avelar, Brandon J Henderso. Upregulation of nAChRs and Changes in Excitability on VTA Dopamine and GABA Neurons Correlates to Changes in Nicotine-Reward-Related Behavior. eNeuro. vol 7. issue 5. 2021-06-18. PMID:32988984. |
here, we use male and female mice that contain α4-mcherry and α6-gfp nachr subunits to show that concentrations of nicotine sufficient to evoke reward-related behavior robustly upregulate α4* and α4α6* nachrs on midbrain dopamine (da) and gaba neurons. |
2021-06-18 |
2023-08-13 |
mouse |
| Zachary A Grieb, Joseph S Lonstei. Oxytocin receptor expression in the midbrain dorsal raphe is dynamic across female reproduction in rats. Journal of neuroendocrinology. vol 33. issue 2. 2021-06-15. PMID:33427399. |
given the chemical heterogeneity of the dr, we then examined otr expression in the three most abundant neuronal phenotypes of the dr (i.e., serotonin, gaba and dopamine) in dioestrous virgins and recently parturient females. |
2021-06-15 |
2023-08-13 |
rat |
| Zachary A Grieb, Joseph S Lonstei. Oxytocin receptor expression in the midbrain dorsal raphe is dynamic across female reproduction in rats. Journal of neuroendocrinology. vol 33. issue 2. 2021-06-15. PMID:33427399. |
overall, these results suggest that the rostral subregion of the midbrain dr is uniquely sensitive to oxytocin around the time of parturition, with subpopulations of cells that become more sensitive (i.e., dopamine), less sensitive (i.e., gaba) and show no change (i.e., serotonin) to this neuropeptide. |
2021-06-15 |
2023-08-13 |
rat |
| Adam Gordon-Fennell, Lydia Gordon-Fennell, Stève Desaivre, Michela Marinell. The Lateral Preoptic Area and Its Projection to the VTA Regulate VTA Activity and Drive Complex Reward Behaviors. Frontiers in systems neuroscience. vol 14. 2021-06-04. PMID:33224029. |
we found that the lpo and the lpo→vta pathway inhibit the activity of vta gaba neurons and have mixed effects on vta dopamine neurons. |
2021-06-04 |
2023-08-13 |
rat |
| T V Davydova, M A Gruden, V S Kudrin, V B Narkevich, L A Vetrile, I A Zakharova, R D E Sewel. Antibodies to Glutamate Facilitate Spatial Memory Formation in the Morris Water Maze in Aging C57BL/6 mice. Bulletin of experimental biology and medicine. vol 169. issue 1. 2021-06-01. PMID:32474668. |
in the prefrontal cortex, dopamine level decreased and the content of its metabolite dopac increased; in parallel, an increase in excitatory and inhibitory amino acids (aspartic acid, glutamate, glycine, taurine, and gaba) was observed. |
2021-06-01 |
2023-08-13 |
mouse |
| Ewa Galaj, Zheng-Xiong X. Progress in opioid reward research: From a canonical two-neuron hypothesis to two neural circuits. Pharmacology, biochemistry, and behavior. vol 200. 2021-05-24. PMID:33227308. |
based on recent findings that activation of dopamine neurons in the ventral tegmental area (vta) and substantia nigra pars compacta (snc) is equally rewarding and that gaba neurons in the rostromedial tegmental nucleus (rmtg) and the substantia nigra pars reticula (snr) are rich in mu opioid receptors and directly synapse onto midbrain da neurons, we proposed that the rtmg→vta → ventrostriatal and snr → snc → dorsostriatal pathways may act as the two major neural substrates underlying opioid reward and abuse. |
2021-05-24 |
2023-08-13 |
Not clear |
| Christin Helmschrodt, Susen Becker, Stefanie Perl, Anja Schulz, Angelika Richte. Development of a fast liquid chromatography-tandem mass spectrometry method for simultaneous quantification of neurotransmitters in murine microdialysate. Analytical and bioanalytical chemistry. vol 412. issue 28. 2021-05-20. PMID:32939566. |
the quantitative analysis of 11 neurotransmitters and metabolites, including serotonin (5-ht), 5-hydroxyindoleacetic acid (5-hiaa), melatonin (me), dopamine (da), levodopa (l-dopa), 3-methoxytyramine (3-mt), norepinephrine (ne), epinephrine (ep), acetylcholine (ach), choline (ch), and γ-aminobutyric acid (gaba), was performed using a biphenyl column coupled to an api-qtrap 3200 (ab sciex) mass spectrometer in positive electrospray ionization mode. |
2021-05-20 |
2023-08-13 |
mouse |
| Shu-Rong Ma, Jin-Bo Yu, Jie Fu, Li-Bin Pan, Hang Yu, Pei Han, Zheng-Wei Zhang, Ran Peng, Hui Xu, Yan Wan. Determination and Application of Nineteen Monoamines in the Gut Microbiota Targeting Phenylalanine, Tryptophan, and Glutamic Acid Metabolic Pathways. Molecules (Basel, Switzerland). vol 26. issue 5. 2021-05-18. PMID:33806510. |
the neurotransmitters and related metabolites included phe, tyrosine (tyr), l-dopa (dopa), dopamine (da), 3-methoxytyramine, trp, hydroxytryptophan, 5-hydroxytryptamine (5-ht), 5-hydroxyindole-3-acetic acid (5-hiaa), kynurenine (kn), kynurenic acid (kyna), melatonin, tryptamine (ta), indole-3-lactic acid (ila), indole-3-acetic acid (iaa), indolyl-3-propionic acid (ipa), glu, gamma-aminobutyric acid (gaba), and acetylcholine (ach). |
2021-05-18 |
2023-08-13 |
Not clear |
| Miguel Perez de la Mora, Carlos Hernandez-Mondragon, Minerva Crespo-Ramirez, José Rejon-Orantes, Dasiel O Borroto-Escuela, Kjell Fux. Conventional and Novel Pharmacological Approaches to Treat Dopamine-Related Disorders: Focus on Parkinson's Disease and Schizophrenia. Neuroscience. vol 439. 2021-05-14. PMID:31349007. |
dopamine released from these neurons operates mainly via the short distance extrasynaptic volume transmission and activates five different dopaminergic receptor subtypes modulating synaptic gaba and glutamate transmission. |
2021-05-14 |
2023-08-13 |
Not clear |
| Farhan Augustine, Shreenath Rajendran, Harvey S Singe. Cortical endogenous opioids and their role in facilitating repetitive behaviors in deer mice. Behavioural brain research. vol 379. 2021-04-30. PMID:31676208. |
in this study, we pursue the mechanism of repetitive behaviors by performing stereological analyses and liquid chromatography/ mass spectrometry (lc-ms/ms) measurements of glutamate (glut), gaba, 3,4-dihydroxyphenylacetic acid (dopac), dopamine (da), leu-enkephalin (leu-enk), and dynorphin-a (dyn-a) in frontal cortex (fc), prefrontal cortex (pfc), and basal ganglia. |
2021-04-30 |
2023-08-13 |
mouse |
| Swati Sahoo, Prashant S Kharkar, Niteshkumar U Sahu, Brijesh . Anxiolytic activity of Psidium guajava in mice subjected to chronic restraint stress and effect on neurotransmitters in brain. Phytotherapy research : PTR. vol 35. issue 3. 2021-04-19. PMID:33034100. |
neurotransmitters such as monoamines (serotonin, norepinephrine, and dopamine), γ-aminobutyric acid (gaba), and glutamate were estimated in different regions of the brain (cortex, hippocampus, and cerebellum and brain stem). |
2021-04-19 |
2023-08-13 |
mouse |
| Farzaneh Saebi Rad, Abbas Haghparast, Afsaneh Eliass. Ventral Tegmental Area Microinjected-SKF38393 Increases Regular Chow Intake in 18 Hours Food-Deprived Rats. Basic and clinical neuroscience. vol 11. issue 6. 2021-04-16. PMID:33850614. |
ventral tegmental area (vta) dopamine neurons play an important role in reward mechanisms of food intake, and vta dopamine receptors exist on the terminal of glutamatergic and gabaergic neurons and regulate gamma-aminobutyric acid (gaba) and glutamate release. |
2021-04-16 |
2023-08-13 |
rat |
| Dasiel O Borroto-Escuela, Karolina Wydra, Ramon Fores-Pons, Lakshmi Vasudevan, Wilber Romero-Fernandez, Małgorzata Frankowska, Luca Ferraro, Sarah Beggiato, Minerva Crespo-Ramirez, Alicia Rivera, Luisa L Rocha, Miguel Perez de la Mora, Christophe Stove, Małgorzata Filip, Kjell Fux. The Balance of MU-Opioid, Dopamine D2 and Adenosine A2A Heteroreceptor Complexes in the Ventral Striatal-Pallidal GABA Antireward Neurons May Have a Significant Role in Morphine and Cocaine Use Disorders. Frontiers in pharmacology. vol 12. 2021-04-02. PMID:33790790. |
the balance of mu-opioid, dopamine d2 and adenosine a2a heteroreceptor complexes in the ventral striatal-pallidal gaba antireward neurons may have a significant role in morphine and cocaine use disorders. |
2021-04-02 |
2023-08-13 |
Not clear |
| Katalin Eszter Ibos, Éva Bodnár, Zsolt Bagosi, Zsolt Bozsó, Gábor Tóth, Gyula Szabó, Krisztina Csabaf. Kisspeptin-8 Induces Anxiety-Like Behavior and Hypolocomotion by Activating the HPA Axis and Increasing GABA Release in the Nucleus Accumbens in Rats. Biomedicines. vol 9. issue 2. 2021-03-16. PMID:33503835. |
gaba release from the nucleus accumbens (nac) and dopamine release from the ventral tegmental area (vta) and nac were measured via ex vivo superfusion. |
2021-03-16 |
2023-08-13 |
rat |
| Ewa Galaj, Xiao Han, Hui Shen, Chloe J Jordan, Yi He, Bree Humburg, Guo-Hua Bi, Zheng-Xiong X. Dissecting the Role of GABA Neurons in the VTA The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 40. issue 46. 2021-02-16. PMID:33046548. |
dissecting the role of gaba neurons in the vta opioid reward has traditionally been thought to be mediated by gaba-induced disinhibition of dopamine (da) neurons in the vta. |
2021-02-16 |
2023-08-13 |
Not clear |
| Giuseppe Di Giovanni, Laura Clara Grandi, Ernesto Fedele, Gergely Orban, Agnese Salvadè, Wei Song, Eleonora Cuboni, Alessandro Stefani, Alain Kaelin-Lang, Salvatore Galat. Acute and Chronic Dopaminergic Depletion Differently Affect Motor Thalamic Function. International journal of molecular sciences. vol 21. issue 8. 2021-02-08. PMID:32326424. |
to shed light on the functional properties of the mth, we examined the effects of acute and chronic dopamine (da) depletion on the neuronal firing of mth neurons, cortical/mth interplay and mth extracellular concentrations of glutamate (glu) and gamma-aminobutyric acid (gaba) in two states of da depletion: acute depletion induced by the tetrodotoxin (ttx) and chronic denervation obtained by 6-hydroxydopamine (6-ohda), both infused into the medial forebrain bundle (mfb) in anesthetized rats. |
2021-02-08 |
2023-08-13 |
rat |