| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yasumi Ohta, Takaaki E Murakami, Mamiko Kawahara, Makito Haruta, Hironari Takehara, Hiroyuki Tashiro, Kiyotaka Sasagawa, Jun Ohta, Metin Akay, Yasemin M Aka. Investigating the Influence of GABA Neurons on Dopamine Neurons in the Ventral Tegmental Area Using Optogenetic Techniques. International journal of molecular sciences. vol 23. issue 3. 2022-02-15. PMID:35163036. |
investigating the influence of gaba neurons on dopamine neurons in the ventral tegmental area using optogenetic techniques. |
2022-02-15 |
2023-08-13 |
mouse |
| Lei Cheng, Baolin Yang, Hua Du, Tong Zhou, Yang Li, Jiajie Wu, Zhenxiao Cao, An X. Moderate intensity of static magnetic fields can alter the avoidance behavior and fat storage of Caenorhabditis elegans via serotonin. Environmental science and pollution research international. 2022-01-29. PMID:35092591. |
the total serotonin level was increased by 17.08% and 16.45% with the treatment of 0.5 t and 1 t smf, compared to the control group; however, there were minimal effects of smfs on other three neurotransmitters including choline, γ-aminobutyric acid (gaba), dopamine. |
2022-01-29 |
2023-08-13 |
human |
| Zhi-Bing You, Eliot L Gardner, Ewa Galaj, Allamar R Moore, Tristram Buck, Chloe J Jordan, Bree A Humburg, Guo-Hua Bi, Zheng-Xiong Xi, Lorenzo Leggi. Involvement of the ghrelin system in the maintenance of oxycodone self-administration: converging evidence from endocrine, pharmacologic and transgenic approaches. Molecular psychiatry. 2022-01-22. PMID:35064236. |
jmv2959 pretreatment significantly inhibited bsr driven by selective stimulation of vta dopamine neurons, but not by stimulation of striatal gaba neurons projecting to the vta in mice. |
2022-01-22 |
2023-08-13 |
mouse |
| Moitreyee Chattopadhyay, Souvik Basak, Atish Barua, Malaya Gupta, Dibyajyoti Das, Tanushree Karmakar, Gautam Kumar Bagch. Neuropharmacological Alterations by a Rice Contaminant Stenotrophomonas maltophilia: a Detailed Bio-molecular and Mechanistic Landscape. Applied biochemistry and biotechnology. 2022-01-10. PMID:35006552. |
throughout the study, both acute and chronic exposure of the cell lysate showed a decrease in the locomotor activity and a time-dependent increase of the depression (p < 0.001-0.0001, two-way anova), supported by bioamine (dopamine, noradrenaline, adrenaline, serotonin, and gaba) depletion in rodents' brain possibly due to ufa-amino acid decarboxylase interaction favoring bioamine depletion as revealed by our study. |
2022-01-10 |
2023-08-13 |
human |
| Giulia Fiscon, Federica Conte, Susanna Amadio, Cinzia Volonté, Paola Pac. Drug Repurposing: A Network-based Approach to Amyotrophic Lateral Sclerosis. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. vol 18. issue 3. 2021-12-11. PMID:33987813. |
among catecholamine, dopamine, serotonin, histamine, and gaba receptor modulators, as well as angiotensin-converting enzymes, cyclooxygenase isozymes, and serotonin transporter inhibitors, we found some interesting no customary als drugs, including amoxapine, clomipramine, mianserin, and modafinil. |
2021-12-11 |
2023-08-13 |
human |
| Liting Sun, Changgeng Peng, Elbert Joosten, Chi Wai Cheung, Fei Tan, Wencheng Jiang, Xiafeng She. Spinal Cord Stimulation and Treatment of Peripheral or Central Neuropathic Pain: Mechanisms and Clinical Application. Neural plasticity. vol 2021. 2021-11-24. PMID:34721569. |
evidence from recent research publications indicates that nociceptive processing at peripheral and central sensory systems is thought to be modulated by scs through (i) inhibition of the ascending nociceptive transmission by the release of analgesic neurotransmitters such as gaba and endocannabinoids at the spinal dorsal horn; (ii) facilitation of the descending inhibition by release of noradrenalin, dopamine, and serotonin acting on their receptors in the spinal cord; and (iii) activation of a variety of supraspinal brain areas related to pain perception and emotion. |
2021-11-24 |
2023-08-13 |
Not clear |
| Masanobu Kogure, Nobuhisa Kanahara, Atsuhiro Miyazawa, Kengo Oishi, Yusuke Nakata, Yasunori Oda, Masaomi Iy. Interacting Roles of COMT and GAD1 Genes in Patients with Treatment-Resistant Schizophrenia: a Genetic Association Study of Schizophrenia Patients and Healthy Controls. Journal of molecular neuroscience : MN. vol 71. issue 12. 2021-11-19. PMID:34125398. |
the impact of interacting effects between dopamine signals and the expression of gaba on the clinical phenotypes of schizophrenia has not been studied. |
2021-11-19 |
2023-08-13 |
human |
| Masanobu Kogure, Nobuhisa Kanahara, Atsuhiro Miyazawa, Kengo Oishi, Yusuke Nakata, Yasunori Oda, Masaomi Iy. Interacting Roles of COMT and GAD1 Genes in Patients with Treatment-Resistant Schizophrenia: a Genetic Association Study of Schizophrenia Patients and Healthy Controls. Journal of molecular neuroscience : MN. vol 71. issue 12. 2021-11-19. PMID:34125398. |
considering the direction of functions of these single-nucleotide polymorphisms revealed by previous studies, we speculate that subjects with the met/cc allelic combination could have a higher dopamine level and a lower expression of gaba in the prefrontal cortex. |
2021-11-19 |
2023-08-13 |
human |
| Lindsey N Friend, Bridget Wu, Jeffrey G Edward. Acute cocaine exposure occludes long-term depression in ventral tegmental area GABA neurons. Neurochemistry international. vol 145. 2021-11-18. PMID:33617930. |
vta dopamine cells are regulated by local inhibitory gaba cells, which exhibit a form of pre-synaptic cannabinoid receptor 1-dependent long-term depression of their glutamatergic inputs. |
2021-11-18 |
2023-08-13 |
mouse |
| Lindsey N Friend, Bridget Wu, Jeffrey G Edward. Acute cocaine exposure occludes long-term depression in ventral tegmental area GABA neurons. Neurochemistry international. vol 145. 2021-11-18. PMID:33617930. |
furthermore, chronic cocaine decreased ampa/nmda ratios at glutamate synapses onto vta gaba cells, compared to vehicle injection controls, the opposite change noted in dopamine cells. |
2021-11-18 |
2023-08-13 |
mouse |
| Lindsey N Friend, Bridget Wu, Jeffrey G Edward. Acute cocaine exposure occludes long-term depression in ventral tegmental area GABA neurons. Neurochemistry international. vol 145. 2021-11-18. PMID:33617930. |
collectively, our data suggest the cellular mechanism of cocaine-mediated synaptic modification that may result in dependence/withdrawal could involve changes in glutamate input to vta gaba circuitry in addition to vta dopamine cells. |
2021-11-18 |
2023-08-13 |
mouse |
| Lindsey N Friend, Bridget Wu, Jeffrey G Edward. Acute cocaine exposure occludes long-term depression in ventral tegmental area GABA neurons. Neurochemistry international. vol 145. 2021-11-18. PMID:33617930. |
therefore vta gaba cells may also play a role, possibly in a synergistic manner with the dopamine circuit, in cocaine-induced changes to the vta reward pathway than previously known. |
2021-11-18 |
2023-08-13 |
mouse |
| Jacqueline-Marie Ferdinand, Kate Z Peters, Ersin Yavas, Andrew M J Youn. Modulation of stimulated dopamine release in rat nucleus accumbens shell by GABA in vitro: Effect of sub-chronic phencyclidine pretreatment. Journal of neuroscience research. vol 99. issue 7. 2021-11-18. PMID:33848365. |
modulation of stimulated dopamine release in rat nucleus accumbens shell by gaba in vitro: effect of sub-chronic phencyclidine pretreatment. |
2021-11-18 |
2023-08-13 |
rat |
| Jacqueline-Marie Ferdinand, Kate Z Peters, Ersin Yavas, Andrew M J Youn. Modulation of stimulated dopamine release in rat nucleus accumbens shell by GABA in vitro: Effect of sub-chronic phencyclidine pretreatment. Journal of neuroscience research. vol 99. issue 7. 2021-11-18. PMID:33848365. |
dopamine signaling in nucleus accumbens (nac) is modulated by γ-aminobutyric acid (gaba), acting through gaba-a and gaba-b receptors: dysregulation of gabaergic control of dopamine function may be important in behavioral deficits in schizophrenia. |
2021-11-18 |
2023-08-13 |
rat |
| Jacqueline-Marie Ferdinand, Kate Z Peters, Ersin Yavas, Andrew M J Youn. Modulation of stimulated dopamine release in rat nucleus accumbens shell by GABA in vitro: Effect of sub-chronic phencyclidine pretreatment. Journal of neuroscience research. vol 99. issue 7. 2021-11-18. PMID:33848365. |
this enduring dysregulation of gaba-b modulation of accumbal dopamine release provides a plausible mechanism through which gaba dysfunction influences accumbal dopamine leading to behavioral changes seen in schizophrenia and may provide a route for novel therapeutic strategies to treat the condition. |
2021-11-18 |
2023-08-13 |
rat |
| Rita Cervera-Juanes, Priscila Darakjian, Megan Ball, Steven G Kohama, Henryk F Urbansk. Effects of estradiol supplementation on the brain transcriptome of old rhesus macaques maintained on an obesogenic diet. GeroScience. 2021-11-12. PMID:34642852. |
synaptogenesis, circadian rhythm, mitochondrial dysfunction, mtor, glutamate, serotonin, gaba, dopamine, epinephrine/norepinephrine, glucocorticoid receptor signaling, neuronal nos, and amyloid processing were exclusively enriched in amg. |
2021-11-12 |
2023-08-13 |
Not clear |
| Serena Boccella, Francesca Guida, Monica Iannotta, Fabio Arturo Iannotti, Rosmara Infantino, Flavia Ricciardi, Claudia Cristiano, Rosa Maria Vitale, Pietro Amodeo, Ida Marabese, Carmela Belardo, Vito de Novellis, Salvatore Paino, Enza Palazzo, Antonio Calignano, Vincenzo Di Marzo, Sabatino Maione, Livio Luong. 2-Pentadecyl-2-oxazoline ameliorates memory impairment and depression-like behaviour in neuropathic mice: possible role of adrenergic alpha2- and H3 histamine autoreceptors. Molecular brain. vol 14. issue 1. 2021-11-04. PMID:33557888. |
treatment for 14 days with pea-oxa after the onset of the symptoms associated with neuropathic pain resulted in the following effects: (i) allodynia was decreased; (ii) affective/cognitive impairment associated with sni (depression, spatial, and working memories) was counteracted; (iii) long-term potentiation in vivo in the lateral entorhinal cortex-dentate gyrus (perforant pathway, lpp) was ameliorated, (iv) hippocampal glutamate, gaba, histamine, norepinephrine and dopamine level alterations after peripheral nerve injury were reversed, (v) expression level of the th positive neurons in the locus coeruleus were normalized. |
2021-11-04 |
2023-08-13 |
mouse |
| T V Davydova, T I Nevidimova, L A Vetrile, I A Zakharova, D N Savochkina, S A Galkin, N A Bokha. Correlation of Antibodies to Neurotransmitters in the Sera of Women with Alcohol Dependence and Depressive Disorders. Bulletin of experimental biology and medicine. vol 171. issue 6. 2021-11-02. PMID:34705169. |
comparative analysis of blood sera from women with alcohol dependence and depressive disorders or from conditionally healthy women revealed reduced level of antibodies to dopamine, norepinephrine, serotonin, glutamate, and gaba in blood serum in women with dysthymic disorder and a depressive episode and their increased content in women with alcohol dependence in combination with depressive disorders. |
2021-11-02 |
2023-08-13 |
Not clear |
| Feng Tai, Che Wang, Xin Deng, Ruojin Li, Zimeng Guo, Haiying Quan, Song L. Treadmill exercise ameliorates chronic REM sleep deprivation-induced anxiety-like behavior and cognitive impairment in C57BL/6J mice. Brain research bulletin. vol 164. 2021-10-29. PMID:32877716. |
after behavioral tests, various neurotransmitters including norepinephrine (ne), dopamine (da), serotonin (5-ht) and γ-aminobutyric acid (gaba) in mouse hippocampus were quantified using high performance liquid chromatography. |
2021-10-29 |
2023-08-13 |
mouse |
| Jordan T Yorgason, Hillary A Wadsworth, Elizabeth J Anderson, Benjamin M Williams, James N Brundage, David M Hedges, Alyssa L Stockard, Stephen T Jones, Summer B Arthur, David Micah Hansen, Nathan D Schilaty, Eun Young Jang, Anna M Lee, Martin Wallner, Scott C Steffense. Modulation of dopamine release by ethanol is mediated by atypical GABA Addiction biology. 2021-10-29. PMID:34713509. |
modulation of dopamine release by ethanol is mediated by atypical gaba previous studies indicate that moderate-to-high ethanol (etoh) concentrations enhance dopamine (da) neurotransmission in the mesolimbic da system from the ventral tegmental area (vta) and projecting to the nucleus accumbens core (nac). |
2021-10-29 |
2023-08-13 |
Not clear |