| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| b' Marc Fakhoury, Giovanni Hernandez, Daniel L\\xc3\\xa9vesque, Pierre-Paul Rompr\\xc3\\xa. Modulation of brain stimulation reward and locomotor activity by ionotropic glutamate receptors of the tail of the ventral tegmental area. Behavioural brain research. vol 393. 2021-10-25. PMID:32593543.' |
the rostromedial tegmental nucleus also referred to as the tail of the ventral tegmental area (tvta) contains a cluster of gamma-aminobutyric acid (gaba)ergic neurons that receive dense glutamatergic afferents from the lateral habenula (lhb), and project to dopamine (da) neurons of the ventral tegmental area (vta) and substantia nigra pars compacta (snc). |
2021-10-25 |
2023-08-13 |
Not clear |
| Steven R Laviolett. Molecular and neuronal mechanisms underlying the effects of adolescent nicotine exposure on anxiety and mood disorders. Neuropharmacology. vol 184. 2021-10-22. PMID:33245960. |
nicotine can potently regulate the transmission of various neurochemicals, including dopamine (da), γ-amino-butyric acid (gaba) and glutamate, within various mesocorticolimbic structures, such as the ventral tegmental area (vta), nucleus accumbens (nac) and prefrontal cortex (pfc), all of which show pathologies in these disorders. |
2021-10-22 |
2023-08-13 |
Not clear |
| Scott A Bullock, Marc N Potenz. Pathological Gambling: Neuropsychopharmacology and Treatment. Current psychopharmacology. vol 1. issue 1. 2021-10-21. PMID:24349964. |
cortico-limbic circuitry involving the ventral striatum, ventromedial prefrontal cortex, anterior cingulate cortex, and dorsolateral prefrontal cortex are discussed as are the neurotransmitters norepinephrine, serotonin, dopamine, opioids, glutamate, and gamma-aminobutyric acid (gaba). |
2021-10-21 |
2023-08-12 |
Not clear |
| Rie Tohge, Satoshi Kaneko, Satoshi Morise, Mitsuaki Oki, Norihiro Takenouchi, Aya Murakami, Masataka Nakamura, Hirofumi Kusaka, Yusuke Yakushij. Zonisamide attenuates the severity of levodopa-induced dyskinesia via modulation of the striatal serotonergic system in a rat model of Parkinson's disease. Neuropharmacology. vol 198. 2021-10-14. PMID:34474045. |
glutamate, gaba, acetylcholine, dopamine, and serotonin interact with each other to regulate the flow of neural information in the striatum. |
2021-10-14 |
2023-08-13 |
rat |
| P A Marathe, S D Satam, S B Raut, Y C Shetty, S G Pooja, A A Raut, P P Kale, N N Reg. Effect of Withania somnifera (L.) Dunal aqueous root extract on reinstatement using conditioned place preference and brain GABA and dopamine levels in alcohol dependent animals. Journal of ethnopharmacology. vol 274. 2021-10-05. PMID:32920131. |
effect of withania somnifera (l.) dunal aqueous root extract on reinstatement using conditioned place preference and brain gaba and dopamine levels in alcohol dependent animals. |
2021-10-05 |
2023-08-13 |
Not clear |
| Susanne Nikolaus, Markus Beu, Hans-Jörg Wittsack, Anja Müller-Lutz, Christina Antke, Hubertus Hautzel, Yuriko Mori, Eduards Mamlins, Gerald Antoch, Hans-Wilhelm Mülle. GABAergic and glutamatergic effects on nigrostriatal and mesolimbic dopamine release in the rat. Reviews in the neurosciences. vol 31. issue 6. 2021-09-24. PMID:32619197. |
in this review, a series of experiments is presented, in which γ-amino butyric acid (gaba)ergic and glutamatergic effects on dopamine function in the rat nigrostriatal and mesolimbic system was systematically assessed after pharmacological challenge with gabaa receptor (r) and and n-methyl d-aspartate (nmda)r agonists and antagonists. |
2021-09-24 |
2023-08-13 |
rat |
| Shuxuan Lyu, Yuan Guo, Li Zhang, Yong Wang, Guoyi Tang, Ruotong Li, Jie Yang, Shasha Gao, Borui Ma, Jian Li. Blockade of GABA transporter-1 and GABA transporter-3 in the lateral habenula improves depressive-like behaviors in a rat model of Parkinson's disease. Neuropharmacology. vol 181. 2021-09-23. PMID:33096108. |
these findings suggest that gat-1 plays a major role in transporting lhb gaba under physiological conditions, and depletion of dopamine increases the transport capacity of gat-3 in the lhb. |
2021-09-23 |
2023-08-13 |
rat |
| Mahesh Bekal, Lue Sun, Susumu Ueno, Takashi Moritak. Neurobehavioral effects of acute low-dose whole-body irradiation. Journal of radiation research. vol 62. issue 5. 2021-09-16. PMID:33982114. |
a serotonin (5-ht), dopamine, gamma-aminobutyric acid (gaba) and cortisol analysis was carried out in blood, hippocampus, amygdala and whole brain tissue. |
2021-09-16 |
2023-08-13 |
mouse |
| Tiago Chaves, Csilla Lea Fazekas, Krisztina Horváth, Pedro Correia, Adrienn Szabó, Bibiána Török, Krisztina Bánrévi, Dóra Zelen. Stress Adaptation and the Brainstem with Focus on Corticotropin-Releasing Hormone. International journal of molecular sciences. vol 22. issue 16. 2021-09-15. PMID:34445795. |
therefore, we aimed to summarize the present knowledge on the role of classical neurotransmitters of the brainstem (gaba, glutamate as well as serotonin, noradrenaline, adrenaline, and dopamine) in stress adaptation. |
2021-09-15 |
2023-08-13 |
Not clear |
| Jorge Miranda-Barrientos, Ian Chambers, Smriti Mongia, Bing Liu, Hui-Ling Wang, Gabriel E Mateo-Semidey, Elyssa B Margolis, Shiliang Zhang, Marisela Morale. Ventral tegmental area GABA, glutamate, and glutamate-GABA neurons are heterogeneous in their electrophysiological and pharmacological properties. The European journal of neuroscience. 2021-08-24. PMID:33619763. |
the ventral tegmental area (vta) contains dopamine neurons intermixed with gaba-releasing (expressing vesicular gaba transporter, vgat), glutamate-releasing (expressing vesicular glutamate transporter 2, vglut2), and glutamate-gaba co-releasing (co-expressing vglut2 and vgat) neurons. |
2021-08-24 |
2023-08-13 |
mouse |
| Beatriz Shantal Jiménez-Zárate, Celia Piña-Leyva, Marina Rodríguez-Sánchez, Benjamín Florán-Garduño, Luis Antonio Jiménez-Zamudio, Ismael Jiménez-Estrad. Day-Night Variations in the Concentration of Neurotransmitters in the Rat Lumbar Spinal Cord. Journal of circadian rhythms. vol 19. 2021-07-31. PMID:34326881. |
the gamma-aminobutyric acid (gaba), glutamate (glu), dopamine, serotonin, epinephrine (e), and norepinephrine (ne) levels in each extracted spinal cord were measured with high-pressure liquid chromatography (hplc)-eq and hplc-fluorescence systems. |
2021-07-31 |
2023-08-13 |
rat |
| Arti Rana, Shamsher Singh, Rahul Deshmukh, Anoop Kuma. Pharmacological potential of tocopherol and doxycycline against traumatic brain injury-induced cognitive/motor impairment in rats. Brain injury. vol 34. issue 8. 2021-07-28. PMID:32493074. |
on 29th day, animals were sacrificed and striatum and cortex were homogenized for the estimation of biochemical (lpo, nitrite, and gsh), neuroinflammatory (il-6, il-1β, and tnf-α), and neurotransmitters (dopamine, norepinephrine, serotonin, gaba, and glutamate) analysis. |
2021-07-28 |
2023-08-13 |
rat |
| Alexandra Münster, Angeline Votteler, Susanne Sommer, Wolfgang Haube. Role of the Medial Orbitofrontal Cortex and Ventral Tegmental Area in Effort-Related Responding. Cerebral cortex communications. vol 1. issue 1. 2021-07-24. PMID:34296142. |
possibly, a reduced excitatory mofc-p drive on pvta gamma-aminobutyric acid (gaba)ergic relays disinhibits vta dopamine neurons which are known to support pr responding. |
2021-07-24 |
2023-08-13 |
rat |
| Regina Célia Cussa Kubrusly, Robertta Silva Martins, Lisiane de Santana Souza, Mariana Pinheiro de Carvalho, Vladimir Pedro Peralva Borges-Martins, Matheus Figueiredo Sathler, Danielle Dias Pinto Ferreira, Maurício Dos Santos Pereira, Ney Ronner Peccinalli, Pablo Pandolfo, Ricardo Augusto de Melo Reis, Gustavo Costa Ferreira, Alex Christian Manhãe. Single Cocaine Exposure Inhibits GABA Uptake via Dopamine D1-Like Receptors in Adolescent Mice Frontal Cortex. Neurotoxicity research. vol 38. issue 3. 2021-07-09. PMID:32696437. |
single cocaine exposure inhibits gaba uptake via dopamine d1-like receptors in adolescent mice frontal cortex. |
2021-07-09 |
2023-08-13 |
mouse |
| William M Doyon, Alexey Ostroumov, Tiahna Ontiveros, Rueben A Gonzales, John A Dan. Ethanol produces multiple electrophysiological effects on ventral tegmental area neurons in freely moving rats. Addiction biology. vol 26. issue 2. 2021-07-08. PMID:32255261. |
vta units were classified as putative dopamine (da) neurons, fast-firing gaba neurons, and unidentified neurons based on a combination of electrophysiological properties and da d |
2021-07-08 |
2023-08-13 |
rat |
| Khadga Raj, G D Gupta, Shamsher Sing. l-Theanine ameliorates motor deficit, mitochondrial dysfunction, and neurodegeneration against chronic tramadol induced rats model of Parkinson's disease. Drug and chemical toxicology. 2021-07-02. PMID:34210222. |
on the day 29, all wistar rats were sacrificed and striatum homogenates were used for biochemical (lipid peroxidation, nitrite, glutathione, glutathione peroxidase activity, superoxide dismutase, catalase, mitochondrial complex i, iv, and cyclic adenosine monophosphate), neuroinflammatory markers (tumor necrosis factor-α, interleukin-1β, and interleukin-17), and neurotransmitters (dopamine, norepinephrine, serotonin, gaba, and glutamate) analysis. |
2021-07-02 |
2023-08-13 |
rat |
| Kyoko Tossell, Rakesh A Dodhia, Benjamin Galet, Olga Tkachuk, Mark A Ungles. Tonic GABAergic inhibition, via GABA The European journal of neuroscience. vol 53. issue 6. 2021-06-29. PMID:33522050. |
tonic gabaergic inhibition, via gaba the activity of midbrain dopamine neurons is strongly regulated by fast synaptic inhibitory γ-aminobutyric acid (gaba)ergic inputs. |
2021-06-29 |
2023-08-13 |
Not clear |
| Daniel C Lowes, Linda A Chamberlin, Lisa N Kretsge, Emma S Holt, Atheir I Abbas, Alan J Park, Lyubov Yusufova, Zachary H Bretton, Ayesha Firdous, Armen G Enikolopov, Joshua A Gordon, Alexander Z Harri. Ventral tegmental area GABA neurons mediate stress-induced blunted reward-seeking in mice. Nature communications. vol 12. issue 1. 2021-06-29. PMID:34112787. |
surprisingly, while previous studies on blunted reward-seeking focused on dopamine (da) transmission from the ventral tegmental area (vta) to the nac, we found that vta gaba, but not da, neurons mediate stress-induced blunted reward-seeking. |
2021-06-29 |
2023-08-13 |
mouse |
| Joanna Peris, Madeline R Steck, Eric G Kraus. Oxytocin treatment for alcoholism: Potential neurocircuitry targets. Neuropharmacology. vol 171. 2021-06-25. PMID:32304701. |
moreover, oxtr are expressed by non-dopaminergic neurons in the vta, such as gaba and glutamate neurons, which can both modulate the activity of dopamine vta neurons locally (in opposite directions) or can project to other brain regions, including the nac, where it can alter either positive reinforcement or aversion caused by ethanol. |
2021-06-25 |
2023-08-13 |
Not clear |
| Riccardo Dore, Regina Krotenko, Jan Philipp Reising, Luca Murru, Sivaraj Mohana Sundaram, Alessandro Di Spiezio, Helge Müller-Fielitz, Markus Schwaninger, Olaf Jöhren, Jens Mittag, Maria Passafaro, Marya Shanabrough, Tamas L Horvath, Carla Schulz, Hendrik Lehner. Nesfatin-1 decreases the motivational and rewarding value of food. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 45. issue 10. 2021-06-23. PMID:32353862. |
we here report that both dopamine and gaba neurons express nucb2/nesfatin-1 in the vta. |
2021-06-23 |
2023-08-13 |
Not clear |