| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A M Batchelor, D J Madge, J Garthwait. Synaptic activation of metabotropic glutamate receptors in the parallel fibre-Purkinje cell pathway in rat cerebellar slices. Neuroscience. vol 63. issue 4. 1995-05-01. PMID:7535396. |
moreover, using an extracellular (grease-gap) technique that monitors population responses, we have previously discovered that, in purkinje cells of adult rat cerebellum, brief tetanic stimulation of the glutamatergic parallel fibre input gives rise to a slow depolarising synaptic potential that is resistant to ionotropic glutamate receptor blockers and to antagonists acting at gaba receptors. |
1995-05-01 |
2023-08-12 |
rat |
| b' Y Garc\\xc3\\xada, C Ibarra, E H Jaff\\xc3\\xa. NMDA and non-NMDA receptor-mediated release of [3H]GABA from granule cell dendrites of rat olfactory bulb. Journal of neurochemistry. vol 64. issue 2. 1995-02-21. PMID:7530292.' |
we have studied the effect of glutamate and the glutamatergic agonists n-methyl-d-aspartate (nmda), kainate, and alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (ampa) on [3h]gaba release from the external plexiform layer of the olfactory bulb. |
1995-02-21 |
2023-08-12 |
rat |
| b' Y Garc\\xc3\\xada, C Ibarra, E H Jaff\\xc3\\xa. NMDA and non-NMDA receptor-mediated release of [3H]GABA from granule cell dendrites of rat olfactory bulb. Journal of neurochemistry. vol 64. issue 2. 1995-02-21. PMID:7530292.' |
the glutamatergic agonists nmda, kainate, and ampa also induced a significant [3h]gaba release. |
1995-02-21 |
2023-08-12 |
rat |
| L Peng, L Hertz, R Huang, U Sonnewald, S B Petersen, N Westergaard, O Larsson, A Schousbo. Utilization of glutamine and of TCA cycle constituents as precursors for transmitter glutamate and GABA. Developmental neuroscience. vol 15. issue 3-5. 1995-02-02. PMID:7805591. |
in the present review evidence is presented that (1) glutamine synthesis in astrocytes is essential for synthesis of gaba in neurons; (2) alpha-ketoglutarate in the presence of alanine (as an amino group donor) can replace glutamine as a precursor for synthesis of transmitter glutamate, but maybe not as a precursor for transmitter gaba; (3) differences exist in the intraneuronal metabolic pathways for utilization of alpha-ketoglutarate plus alanine and of glutamine, and (4) alanine also functions as a substrate for oxidative metabolism in glutamatergic neurons. |
1995-02-02 |
2023-08-12 |
Not clear |
| L Peng, L Hertz, R Huang, U Sonnewald, S B Petersen, N Westergaard, O Larsson, A Schousbo. Utilization of glutamine and of TCA cycle constituents as precursors for transmitter glutamate and GABA. Developmental neuroscience. vol 15. issue 3-5. 1995-02-02. PMID:7805591. |
it should be emphasized that the supply of precursors for transmitter glutamate and gaba in glutamatergic and gabaergic neurons depends on metabolic processes in astrocytes regardless whether glutamine or alpha-ketoglutarate plus l-alanine function as the transmitter precursors. |
1995-02-02 |
2023-08-12 |
Not clear |
| S K Suneja, C G Benson, J Gross, S J Potashne. Evidence for glutamatergic projections from the cochlear nucleus to the superior olive and the ventral nucleus of the lateral lemniscus. Journal of neurochemistry. vol 64. issue 1. 1995-01-24. PMID:7798910. |
to determine if cn efferents were glutamatergic and/or aspartatergic, the fresh brainstem was sectioned transversely and samples of the lso, mso, mntb, vnll, and icc were taken to measure the electrically evoked release and the uptake of d-[3h]asp and [14c]gly or [14c]gaba 3-5 days after the cn ablation. |
1995-01-24 |
2023-08-12 |
Not clear |
| Y Ben-Ari, V Tseeb, D Raggozzino, R Khazipov, J L Gaiars. gamma-Aminobutyric acid (GABA): a fast excitatory transmitter which may regulate the development of hippocampal neurones in early postnatal life. Progress in brain research. vol 102. 1995-01-24. PMID:7800817. |
gaba, acting on gabaa receptors, provides most of the excitatory drive on immature ca3 pyramidal neurones at an early stage of development, whereas glutamatergic synapses (in particular, those mediated by ampa receptors) are mostly quiescent. |
1995-01-24 |
2023-08-12 |
Not clear |
| A O Donoso, A M Seltzer, C E Navarro, R J Cabrera, F J López, A Negro-Vila. Regulation of luteinizing hormone-releasing hormone and luteinizing hormone secretion by hypothalamic amino acids. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 27. issue 4. 1994-10-19. PMID:8087094. |
increasing endogenous gaba concentration by drugs, gaba agonists, or blockade of glutamatergic neurotransmission by selective antagonists in rats and non-human primates prevents ovulation and pulsatile lh release, and blunts the lh surges induced by estrogen or an estrogen-progesterone combination. |
1994-10-19 |
2023-08-12 |
rat |
| J Lewald, E W Petrasch-Parwez, R W Ve. GABA-like and glutamate-like immunoreactivity in the pretecto-olivary pathway in the rat. Journal fur Hirnforschung. vol 35. issue 2. 1994-09-16. PMID:7914903. |
the results suggest that the projection neurons receive a strong inhibitory input mediated by gaba and send their directionally selective information to the inferior olive by glutamatergic projections. |
1994-09-16 |
2023-08-12 |
rat |
| N N Osborne, A J Herrer. The effect of experimental ischaemia and excitatory amino acid agonists on the GABA and serotonin immunoreactivities in the rabbit retina. Neuroscience. vol 59. issue 4. 1994-09-12. PMID:7520132. |
the aim of the described experiments was to use immunohistochemistry to visualize the release of gaba from specific retinal amacrine cells following ischaemia and to establish the involvement of defined glutamatergic receptors. |
1994-09-12 |
2023-08-12 |
rabbit |
| A N Katchman, S Vicini, N Hershkowit. Mechanism of early anoxia-induced suppression of the GABAA-mediated inhibitory postsynaptic current. Journal of neurophysiology. vol 71. issue 3. 1994-07-06. PMID:8201407. |
all subsequent studies examined the gabaa-mediated ipsc synaptic responses in isolation by direct stimulation of gaba interneurons in the stratum radiatum in the presence of extracellular 3-(2-carboxypiperazine-4-yl)propyl-1-phosphonic acid (cpp) (20 microm) and 6-cyano-7-nitroquinoxaline-2,3-dione (cnqx) (50 microm) to block glutamatergic currents and intracellular qx-314 (lidocaine n-ethyl bromide, 1 mm) to block gabab-mediated currents. |
1994-07-06 |
2023-08-12 |
rat |
| S S Oja, P Saransaari, U Wysmyk, J Albrech. Loss of GABAB binding sites in the cerebral cortex of rats with acute hepatic encephalopathy. Brain research. vol 629. issue 2. 1994-03-25. PMID:8111641. |
since gabab receptors control the cerebral cortical release of the amino acid neurotransmitters glutamate and gaba, the loss of gabab receptors is likely to contribute to the array of disturbances of glutamatergic and gabaergic neurotransmission known to accompany he. |
1994-03-25 |
2023-08-12 |
rat |
| J S Isaacson, R A Nicol. The uptake inhibitor L-trans-PDC enhances responses to glutamate but fails to alter the kinetics of excitatory synaptic currents in the hippocampus. Journal of neurophysiology. vol 70. issue 5. 1994-02-25. PMID:7905032. |
however, in marked contrast to fast gamma-aminobutyric acid a (gabaa) synapses in the hippocampus, uptake does not appear to play a role in regulating the "spill-over" of transmitter from neighboring, co-activated glutamatergic synapses. |
1994-02-25 |
2023-08-12 |
Not clear |
| P DeBoer, B H Westerin. GABAergic modulation of striatal cholinergic interneurons: an in vivo microdialysis study. Journal of neurochemistry. vol 62. issue 1. 1994-01-24. PMID:8263546. |
we hypothesize that although gabaa mediated regulation of striatal ach occurs via gaba receptors on the cholinergic neuron, the gabab mediated effects may be explained by presynaptic inhibition of the glutamatergic input of the striatal cholinergic neuron. |
1994-01-24 |
2023-08-12 |
Not clear |
| K Campbell, P Kalén, K Wictorin, C Lundberg, R J Mandel, A Björklun. Characterization of GABA release from intrastriatal striatal transplants: dependence on host-derived afferents. Neuroscience. vol 53. issue 2. 1993-06-11. PMID:8098510. |
furthermore, the graft-derived gaba release appears to be under normal regulatory control from the host dopaminergic and glutamatergic systems. |
1993-06-11 |
2023-08-12 |
rat |
| A Richter, W Lösche. Alterations in pharmacological sensitivity of GABAergic but not dopaminergic and glutamatergic systems during ontogenesis in dystonic mutant hamsters. European journal of pharmacology. vol 231. issue 1. 1993-04-05. PMID:8383061. |
in the present experiments, it was examined whether dystonic hamsters exhibit age-dependent differences in susceptibility to drugs which affect gaba (gamma-aminobutyrate)ergic, glutamatergic or dopaminergic functions. |
1993-04-05 |
2023-08-12 |
Not clear |
| A Nieoullon, L Kerkerian-Le Gof. Cellular interactions in the striatum involving neuronal systems using "classical" neurotransmitters: possible functional implications. Movement disorders : official journal of the Movement Disorder Society. vol 7. issue 4. 1993-02-18. PMID:1362449. |
the key role of cholinergic interneurons in the striatum may therefore be attributable to the fact that they modulate the glutamatergic transmission to gaba striatal efferent neurons. |
1993-02-18 |
2023-08-11 |
Not clear |
| J Gigg, A M Tan, D M Finc. Glutamatergic excitatory responses of anterior cingulate neurons to stimulation of the mediodorsal thalamus and their regulation by GABA: an in vivo iontophoretic study. Cerebral cortex (New York, N.Y. : 1991). vol 2. issue 6. 1993-02-11. PMID:1282403. |
glutamatergic excitatory responses of anterior cingulate neurons to stimulation of the mediodorsal thalamus and their regulation by gaba: an in vivo iontophoretic study. |
1993-02-11 |
2023-08-11 |
rat |
| J Gigg, A M Tan, D M Finc. Glutamatergic excitatory responses of anterior cingulate neurons to stimulation of the mediodorsal thalamus and their regulation by GABA: an in vivo iontophoretic study. Cerebral cortex (New York, N.Y. : 1991). vol 2. issue 6. 1993-02-11. PMID:1282403. |
these data suggest that the thalamic projection to anterior cingulate cortex is glutamatergic, acting principally via ampa receptors, and that the response of cingulate neurons to thalamic stimulation is regulated by gaba acting at both gabaa and gabab receptors. |
1993-02-11 |
2023-08-11 |
rat |
| L Hertz, A C Yu, A Schousbo. Uptake and metabolism of malate in neurons and astrocytes in primary cultures. Journal of neuroscience research. vol 33. issue 2. 1993-01-06. PMID:1453491. |
uptake and oxidative metabolism of [14c]malate as well as its incorporation into aspartate, glutamate, glutamine, and gaba were studied in cultured cerebral cortical neurons (gabaergic), cerebellar granule neurons (glutamatergic), and cerebral cortical astrocytes. |
1993-01-06 |
2023-08-11 |
Not clear |