| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| T Dennis, O Curet, T Nishikawa, B Scatto. Further evidence for, and nature of, the facilitatory GABAergic influence on central noradrenergic transmission. Naunyn-Schmiedeberg's archives of pharmacology. vol 331. issue 2-3. 1986-03-03. PMID:3003590. |
these data indicate that the gabaergic influence is not exerted via gaba receptors located on noradrenergic cell bodies or nerve endings. |
1986-03-03 |
2023-08-11 |
rat |
| L Beani, S Tanganelli, T Antonelli, C Bianch. Noradrenergic modulation of cortical acetylcholine release is both direct and gamma-aminobutyric acid-mediated. The Journal of pharmacology and experimental therapeutics. vol 236. issue 1. 1986-02-20. PMID:3001287. |
the effect of norepinephrine (ne) on the outflow of gamma-aminobutyric acid (gaba) as well as the influence of endogenous gaba on ne-induced inhibition of acetylcholine (ach) release have been investigated in guinea-pig cortical slices, in order to clarify the role of this amino acid in the noradrenergic control of the cholinergic signal. |
1986-02-20 |
2023-08-11 |
Not clear |
| R S Flint, W J McBrid. Assessment of some transmitter actions in rat cerebellar slices. Life sciences. vol 38. issue 3. 1986-02-18. PMID:2867450. |
these data suggest a cholinergic, gabaergic and glutamatergic control of the noradrenergic system in the cerebellum; the presence of a specific aspartergic system in the cerebellum; and a net excitatory action of gaba may be present within the cerebellum. |
1986-02-18 |
2023-08-11 |
rat |
| A O Donos. Localization in the brain of the inhibition by GABA of luteinizing hormone release that follows orchidectomy in rats. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 18. issue 1. 1986-01-10. PMID:4063553. |
the present preliminary results suggest that the increase of gaba at synaptic sites affects luteinizing hormone release in castrated male rats through an action on the noradrenergic cell bodies of the locus ceruleus system. |
1986-01-10 |
2023-08-11 |
rat |
| P D Suzdak, G Gianutso. Parallel changes in the sensitivity of gamma-aminobutyric acid and noradrenergic receptors following chronic administration of antidepressant and GABAergic drugs. A possible role in affective disorders. Neuropharmacology. vol 24. issue 3. 1985-06-18. PMID:2986038. |
parallel changes in the sensitivity of gamma-aminobutyric acid and noradrenergic receptors following chronic administration of antidepressant and gabaergic drugs. |
1985-06-18 |
2023-08-11 |
Not clear |
| P D Suzdak, G Gianutso. Parallel changes in the sensitivity of gamma-aminobutyric acid and noradrenergic receptors following chronic administration of antidepressant and GABAergic drugs. A possible role in affective disorders. Neuropharmacology. vol 24. issue 3. 1985-06-18. PMID:2986038. |
chronic treatment with the antidepressants imipramine or nomifensine, or the gamma-aminobutyric acid (gabaergic) agents, baclofen or thip, produced a decrease in the bmax for binding sites of gabaergic and noradrenergic receptors. |
1985-06-18 |
2023-08-11 |
Not clear |
| P D Suzdak, G Gianutso. Parallel changes in the sensitivity of gamma-aminobutyric acid and noradrenergic receptors following chronic administration of antidepressant and GABAergic drugs. A possible role in affective disorders. Neuropharmacology. vol 24. issue 3. 1985-06-18. PMID:2986038. |
these results suggest a possible link between the gabaergic and noradrenergic systems, which may be important in understanding the mechanism of action of antidepressant drugs, and suggests a possible role for gaba in affective disorders. |
1985-06-18 |
2023-08-11 |
Not clear |
| G Bartholin. GABA receptor agonists: pharmacological spectrum and therapeutic actions. Medicinal research reviews. vol 5. issue 1. 1985-04-29. PMID:2984490. |
the fact that: (a) gaba receptor agonists and tricyclic antidepressants affect noradrenergic and serotonergic transmission differently; and (b) tricyclic antidepressants alter gaba-related parameters challenges the classical monoamine hypothesis of depression and suggests that gaba-mediated mechanisms play a role in mood disorders. |
1985-04-29 |
2023-08-11 |
human |
| b' H H Hennies, W A G\\xc3\\xbcnzler, L Floh\\xc3\\xa. Influence of supidimide on brain neurotransmitter systems of rats and mice. Arzneimittel-Forschung. vol 34. issue 11. 1985-03-14. PMID:6084511.' |
the influence of 2-(2-oxo-3-piperidyl)-1,2-benzisothiazoline-3-one-1, 1-dioxide (supidimide), a representative of a new class of sedative drugs, on the noradrenergic, dopaminergic, serotoninergic and gamma-aminobutyric acid (gaba)ergic neuronal systems of rodent brains was investigated. |
1985-03-14 |
2023-08-12 |
mouse |
| J C Blanchard, A Boireau, L Julo. Brain receptors and zopiclone. International pharmacopsychiatry. vol 17 Suppl 2. 1984-08-13. PMID:6329982. |
no other brain receptors such as gamma-aminobutyric acid receptor, dopamine receptor, serotonin and noradrenergic receptors are reached by zpc. |
1984-08-13 |
2023-08-12 |
rat |
| J C Blanchard, A Boireau, L Julo. Brain receptors and zopiclone. Pharmacology. vol 27 Suppl 2. 1984-04-17. PMID:6322210. |
no other brain receptors such as gamma-aminobutyric acid receptor, dopamine receptor, serotonin and noradrenergic receptors are reached by zpc. |
1984-04-17 |
2023-08-12 |
rat |
| D S Charney, D E Redmon. Neurobiological mechanisms in human anxiety. Evidence supporting central noradrenergic hyperactivity. Neuropharmacology. vol 22. issue 12B. 1984-04-03. PMID:6142428. |
future studies will need to evaluate, in addition to central noradrenergic function, other neuronal systems in brain involving endogenous opioids, benzodiazepine receptors, purines and gamma-aminobutyric acid in human anxiety disorders. |
1984-04-03 |
2023-08-12 |
human |
| B D Waterhouse, H C Moises, H H Yeh, H M Geller, D J Woodwar. Comparison of norepinephrine- and benzodiazepine-induced augmentation of Purkinje cell responses to gamma-aminobutyric acid (GABA). The Journal of pharmacology and experimental therapeutics. vol 228. issue 2. 1984-03-20. PMID:6319673. |
although gaba facilitation by ne was unaffected by acute systemic administration of a benzodiazepine, chronic treatment with flurazepam produced a subsensitivity to the noradrenergic gaba facilitating effects. |
1984-03-20 |
2023-08-12 |
rat |
| B D Waterhouse, H C Moises, H H Yeh, H M Geller, D J Woodwar. Comparison of norepinephrine- and benzodiazepine-induced augmentation of Purkinje cell responses to gamma-aminobutyric acid (GABA). The Journal of pharmacology and experimental therapeutics. vol 228. issue 2. 1984-03-20. PMID:6319673. |
thus, although flurazepam appears to act independently from the noradrenergic receptor system in augmenting gaba-induced depression of purkinje cell discharge, a reversible subsensitivity to the gaba facilitating effects of both flurazepam and ne can be produced by chronic treatment with this benzodiazepine. |
1984-03-20 |
2023-08-12 |
rat |
| B D Waterhouse, H C Moises, H H Yeh, H M Geller, D J Woodwar. Comparison of norepinephrine- and benzodiazepine-induced augmentation of Purkinje cell responses to gamma-aminobutyric acid (GABA). The Journal of pharmacology and experimental therapeutics. vol 228. issue 2. 1984-03-20. PMID:6319673. |
on the basis of this "cross-subsensitivity" to ne and flurazepam actions, it seems reasonable to suggest that these two agents might enhance gaba inhibitory actions by a common biophysical mechanism subsequent to noradrenergic receptor activation. |
1984-03-20 |
2023-08-12 |
rat |
| H H Yeh, D J Woodwar. Noradrenergic action in the developing rat cerebellum: interaction between norepinephrine and gamma-aminobutyric acid applied microiontophoretically to immature Purkinje cells. Brain research. vol 312. issue 1. 1984-02-20. PMID:6418331. |
noradrenergic action in the developing rat cerebellum: interaction between norepinephrine and gamma-aminobutyric acid applied microiontophoretically to immature purkinje cells. |
1984-02-20 |
2023-08-12 |
rat |
| H H Yeh, D J Woodwar. Beta-1 adrenergic receptors mediate noradrenergic facilitation of Purkinje cell responses to gamma-aminobutyric acid in cerebellum of rat. Neuropharmacology. vol 22. issue 5. 1983-09-20. PMID:6308495. |
beta-1 adrenergic receptors mediate noradrenergic facilitation of purkinje cell responses to gamma-aminobutyric acid in cerebellum of rat. |
1983-09-20 |
2023-08-12 |
rat |
| H H Yeh, D J Woodwar. Beta-1 adrenergic receptors mediate noradrenergic facilitation of Purkinje cell responses to gamma-aminobutyric acid in cerebellum of rat. Neuropharmacology. vol 22. issue 5. 1983-09-20. PMID:6308495. |
this noradrenergic facilitation of gaba has been shown recently to be mediated by beta-adrenergic receptors. |
1983-09-20 |
2023-08-12 |
rat |
| D V Jeste, R J Wyat. Therapeutic strategies against tardive dyskinesia. Two decades of experience. Archives of general psychiatry. vol 39. issue 7. 1983-04-07. PMID:6131655. |
putative gamma-aminobutyric acid (gaba)-ergic drugs and noradrenergic blockers deserve careful study. |
1983-04-07 |
2023-08-12 |
Not clear |
| S J Grant, D E Redmon. The neuroanatomy and pharmacology of the nucleus locus coeruleus. Progress in clinical and biological research. vol 71. 1982-04-22. PMID:6276901. |
receptors for gaba, endorphins, substance p, and ach on lc neurons provide an anatomical and physiological basis for interactions among systems utilizing these substances as neurotransmitters in that they act on a common final noradrenergic pathway. |
1982-04-22 |
2023-08-12 |
Not clear |