| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A O Donos. Localized increase of GABA levels in brain areas of the rat and inhibition of the plasma LH rise following orchidectomy. Neuroendocrinology. vol 48. issue 2. 1989-03-23. PMID:3221982. |
previous studies have suggested that gamma-aminobutyric acid (gaba) exerts inhibitory actions on luteinizing hormone (lh) secretion that are likely to be mediated by modifications in noradrenergic transmission. |
1989-03-23 |
2023-08-11 |
rat |
| J Yamamot. Roles of cholinergic, dopaminergic, noradrenergic, serotonergic and GABAergic systems in changes of the EEG power spectra and behavioral states in rabbits. Japanese journal of pharmacology. vol 47. issue 2. 1989-01-26. PMID:3199590. |
in the present study, the influences of cholinergic (ach), dopaminergic (da), noradrenergic, serotonergic and gamma-aminobutyric acid (gaba) ergic system activation and blocking agents on the cortical (ct) and hippocampal (hc) eeg power spectra were investigated in rabbits. |
1989-01-26 |
2023-08-11 |
Not clear |
| L Beani, C Bianchi, S Tanganelli, T Antonelli, M Simonato, S Rand. Inversion of the alpha-2 and alpha-1 noradrenergic control of the cortical release of acetylcholine and gamma-aminobutyric acid in morphine-tolerant guinea pigs. The Journal of pharmacology and experimental therapeutics. vol 247. issue 1. 1988-11-18. PMID:2845056. |
inversion of the alpha-2 and alpha-1 noradrenergic control of the cortical release of acetylcholine and gamma-aminobutyric acid in morphine-tolerant guinea pigs. |
1988-11-18 |
2023-08-11 |
Not clear |
| R Hoehn-Saric, D R McLeod, W D Zimmerl. Differential effects of alprazolam and imipramine in generalized anxiety disorder: somatic versus psychic symptoms. The Journal of clinical psychiatry. vol 49. issue 8. 1988-10-12. PMID:3045099. |
the authors' results suggest that, in generalized anxiety, somatic symptoms and hyperarousal selectively respond to drugs acting on the gamma-aminobutyric acid system, whereas psychic symptoms respond to treatments affecting the noradrenergic or serotonergic systems. |
1988-10-12 |
2023-08-11 |
Not clear |
| D W Bonhaus, J O McNamar. Anticonvulsant action of intranigral gamma-vinyl-GABA: role of nonadrenergic neurotransmission. Brain research. vol 438. issue 1-2. 1988-04-18. PMID:2830944. |
consequently, we tested the idea that intranigral gaba mimetics suppress es by increasing noradrenergic (ne) neuronal activity. |
1988-04-18 |
2023-08-11 |
Not clear |
| D Bitran, E M Hul. Pharmacological analysis of male rat sexual behavior. Neuroscience and biobehavioral reviews. vol 11. issue 4. 1988-03-28. PMID:2830564. |
evidence is presented that: (1) serotonergic influence is generally inhibitory to sexual behavior, although two receptor subtypes may lower ejaculation threshold; (2) dopaminergic agonists facilitate several aspects of copulatory behavior and ex copula genital responses; (3) noradrenergic activity appears to increase sexual arousal; (4) cholinergic agonists facilitate ejaculation, or in some cases, delay or prevent initiation of copulation; (5) gaba agonists inhibit sexual responses both in and ex copula; (6) opiate agonists appear to inhibit copulation and penile reflexes, although antagonists have mixed effects; (7) acth and msh peptides promote copulatory behavior and genital responses; (8) oxytocin facilitates ex copula penile responses, but may contribute to postejaculatory refractoriness; and (9) long-term exposure to prolactin inhibits sexual behavior and penile responses. |
1988-03-28 |
2023-08-11 |
rat |
| M Daoust, C Saligaut, J P Lhuintre, N Moore, J L Flipo, F Boismar. GABA transmission, but not benzodiazepine receptor stimulation, modulates ethanol intake by rats. Alcohol (Fayetteville, N.Y.). vol 4. issue 6. 1988-03-25. PMID:2829943. |
an intervention of gaba b receptors on noradrenergic pathways was also evoked. |
1988-03-25 |
2023-08-11 |
rat |
| M Daoust, J P Lhuintre, C Saligaut, N Moore, J L Flipo, F Boismar. Noradrenaline and GABA brain receptors are co-involved in the voluntary intake of ethanol by rats. Alcohol and alcoholism (Oxford, Oxfordshire). Supplement. vol 1. 1988-03-23. PMID:2827695. |
stimulation of gaba brain receptors by calcium bis acetyl-homotaurine (a new gabaergic agent) or of noradrenergic brain receptors by metapramine reduces the voluntary intake of ethanol by rats. |
1988-03-23 |
2023-08-11 |
rat |
| b' M Poncelet, P Martin, S Danti, P Simon, P Soubri\\xc3\\xa. Noradrenergic rather than GABAergic processes as the common mediation of the antidepressant profile of GABA agonists and imipramine-like drugs in animals. Pharmacology, biochemistry, and behavior. vol 28. issue 3. 1988-01-11. PMID:3685065.' |
noradrenergic rather than gabaergic processes as the common mediation of the antidepressant profile of gaba agonists and imipramine-like drugs in animals. |
1988-01-11 |
2023-08-11 |
rat |
| b' M Poncelet, P Martin, S Danti, P Simon, P Soubri\\xc3\\xa. Noradrenergic rather than GABAergic processes as the common mediation of the antidepressant profile of GABA agonists and imipramine-like drugs in animals. Pharmacology, biochemistry, and behavior. vol 28. issue 3. 1988-01-11. PMID:3685065.' |
on the basis of these data, it is tempting to speculate that increased transmitter outflow at noradrenergic receptors may be an essential component in the mechanism of action of imipramine-like drugs but also of gaba agonists. |
1988-01-11 |
2023-08-11 |
rat |
| F J Miñano, M Sancibrian, J S Serran. Hypothermic effect of GABA in conscious stressed rats: its modification by cholinergic agonists and antagonists. The Journal of pharmacy and pharmacology. vol 39. issue 9. 1987-12-21. PMID:2890737. |
the results support the hypothesis of nicotinic presynaptic receptors modulating noradrenergic nerve endings that play a part in the hypothermic response of gaba. |
1987-12-21 |
2023-08-11 |
rat |
| R Gervai. Local GABAergic modulation of noradrenaline release in the rat olfactory bulb measured on superfused slices. Brain research. vol 400. issue 1. 1987-03-30. PMID:3028565. |
ascending noradrenergic projections from locus coeruleus reaching the rat olfactory bulb (ob) synapse onto gamma-aminobutyric acid (gaba)-ergic interneurons. |
1987-03-30 |
2023-08-11 |
rat |
| B Scatton, A Serran. GABA mimetics increase extracellular DOPAC (as measured by in vivo voltammetry) in the rat locus coeruleus. Naunyn-Schmiedeberg's archives of pharmacology. vol 332. issue 4. 1986-09-16. PMID:3736682. |
previous studies have suggested that gaba exerts an indirect facilitatory influence on cerebral noradrenergic transmission that is likely to be mediated via gaba-ergic synapses involved in polysynaptic neuronal circuits controlling noradrenergic cell activity. |
1986-09-16 |
2023-08-11 |
rat |
| B Scatton, A Serran. GABA mimetics increase extracellular DOPAC (as measured by in vivo voltammetry) in the rat locus coeruleus. Naunyn-Schmiedeberg's archives of pharmacology. vol 332. issue 4. 1986-09-16. PMID:3736682. |
in order to confirm these findings, we have studied the effect of gaba mimetics on extracellular dopac in the locus coeruleus (a reliable index of noradrenergic neuronal activity) of the rat through the use of in vivo voltammetry with carbon fibre electrodes. |
1986-09-16 |
2023-08-11 |
rat |
| B Scatton, A Serran. GABA mimetics increase extracellular DOPAC (as measured by in vivo voltammetry) in the rat locus coeruleus. Naunyn-Schmiedeberg's archives of pharmacology. vol 332. issue 4. 1986-09-16. PMID:3736682. |
these results add further weight to the view that gaba exerts a facilitatory influence on noradrenergic neurons (via an increase in their cell firing) which is not effected at the level of their cell bodies or in the surrounding region. |
1986-09-16 |
2023-08-11 |
rat |
| A S Eison, D L Templ. Buspirone: review of its pharmacology and current perspectives on its mechanism of action. The American journal of medicine. vol 80. issue 3B. 1986-04-25. PMID:2870639. |
the uniform depressant action of the benzodiazepines upon serotonergic, noradrenergic, and dopaminergic cell firing may result from their facilitatory effect on gamma-aminobutyric acid and its known inhibitory influence in these monoaminergic areas. |
1986-04-25 |
2023-08-11 |
Not clear |
| T Lerner, J Feldon, M S Myslobodsk. Amphetamine potentiation of anti-conflict action of chlordiazepoxide. Pharmacology, biochemistry, and behavior. vol 24. issue 2. 1986-04-15. PMID:3513210. |
the disinhibitory effects of amphetamine coadministered with cdp were discussed in terms of a possible enhanced noradrenergic or dopaminergic activity and their interaction with gaba neurotransmission at gaba-benzodiazepine coupled sites. |
1986-04-15 |
2023-08-11 |
rat |
| T Dennis, O Curet, T Nishikawa, B Scatto. Further evidence for, and nature of, the facilitatory GABAergic influence on central noradrenergic transmission. Naunyn-Schmiedeberg's archives of pharmacology. vol 331. issue 2-3. 1986-03-03. PMID:3003590. |
in order to explore the nature of the facilitatory gabaergic control of cerebral noradrenergic neurons, we have studied the effect of a variety of gaba mimetics (given systemically or injected locally into brain areas containing noradrenergic cell bodies or terminals) on several indices of noradrenaline turnover in the rat brain. |
1986-03-03 |
2023-08-11 |
rat |
| T Dennis, O Curet, T Nishikawa, B Scatto. Further evidence for, and nature of, the facilitatory GABAergic influence on central noradrenergic transmission. Naunyn-Schmiedeberg's archives of pharmacology. vol 331. issue 2-3. 1986-03-03. PMID:3003590. |
systemic administration of both direct and indirect acting gaba mimetics enhanced; 1) the pargyline induced accumulation of normetanephrine in the hypothalamus; 2) total dopeg levels in a number of brain regions innervated by noradrenergic neurons; 3) both dopac and mopeg levels in noradrenergic cell body areas (a1, a2 and a6). |
1986-03-03 |
2023-08-11 |
rat |
| T Dennis, O Curet, T Nishikawa, B Scatto. Further evidence for, and nature of, the facilitatory GABAergic influence on central noradrenergic transmission. Naunyn-Schmiedeberg's archives of pharmacology. vol 331. issue 2-3. 1986-03-03. PMID:3003590. |
thus, the acceleration of noradrenaline turnover induced by gaba mimetics appears to depend on ongoing activity in noradrenergic neurons and occurs via an increase in neuronal discharges. |
1986-03-03 |
2023-08-11 |
rat |