| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J M Lauder, J Liu, L Devaud, A L Morro. GABA as a trophic factor for developing monoamine neurons. Perspectives on developmental neurobiology. vol 5. issue 2-3. 1998-12-16. PMID:9777640. |
evidence that gaba regulates development of these and adjacent noradrenergic neurons has recently been obtained using embryonic brainstem cultures, which contain differentiating 5-ht, tyrosine hydroxylase (th), and gaba neurons. |
1998-12-16 |
2023-08-12 |
Not clear |
| Y F Wang, I Shibuya, N Kabashima, V S Setiadji, T Isse, Y Ueta, H Yamashit. Inhibition of spontaneous inhibitory postsynaptic currents (IPSC) by noradrenaline in rat supraoptic neurons through presynaptic alpha2-adrenoceptors. Brain research. vol 807. issue 1-2. 1998-12-10. PMID:9756995. |
these results suggest that noradrena-line inhibits release of gaba from the presynaptic gabaergic terminals of the supraoptic neurons by activating presynaptic alpha2-adrenoceptors and such presynaptic mechanisms may play a role in the excitatory control of son neurons by noradrenergic neurons. |
1998-12-10 |
2023-08-12 |
rat |
| D Gervasoni, L Darracq, P Fort, F Soulière, G Chouvet, P H Lupp. Electrophysiological evidence that noradrenergic neurons of the rat locus coeruleus are tonically inhibited by GABA during sleep. The European journal of neuroscience. vol 10. issue 3. 1998-10-22. PMID:9753163. |
electrophysiological evidence that noradrenergic neurons of the rat locus coeruleus are tonically inhibited by gaba during sleep. |
1998-10-22 |
2023-08-12 |
rat |
| D Gervasoni, L Darracq, P Fort, F Soulière, G Chouvet, P H Lupp. Electrophysiological evidence that noradrenergic neurons of the rat locus coeruleus are tonically inhibited by GABA during sleep. The European journal of neuroscience. vol 10. issue 3. 1998-10-22. PMID:9753163. |
we found that iontophoretic application of bicuculline, a specific gaba(a)-receptor antagonist, during ps and sws restore a tonic firing in the lc noradrenergic neurons. |
1998-10-22 |
2023-08-12 |
rat |
| I S Shiah, L N Yatha. GABA function in mood disorders: an update and critical review. Life sciences. vol 63. issue 15. 1998-10-22. PMID:9768867. |
given that gaba has an inhibitory effect on biogenic amine neurotransmitters such as norepinephrine and serotonin and this inhibition may be involved in local circuits and interneurons, it has been suggested that the hypothesis of a gaba deficit in mood disorders does not compete with but complements the well-established hypotheses of alterations in noradrenergic and serotonergic function in mood disorders. |
1998-10-22 |
2023-08-12 |
Not clear |
| S Geyer, M Matelli, G Luppino, A Schleicher, Y Jansen, N Palomero-Gallagher, K Zille. Receptor autoradiographic mapping of the mesial motor and premotor cortex of the macaque monkey. The Journal of comparative neurology. vol 397. issue 2. 1998-09-25. PMID:9658286. |
alpha-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid (ampa), kainate, and n-methyl-d-aspartate (nmda) binding sites were labeled with [3h]ampa, [3h]kainate, and [3h]mk-801, respectively, muscarinic binding sites with [3h]pirenzepine or [3h]oxotremorine-m, noradrenergic binding sites with [3h]prazosin or [3h]uk-14304, gamma-aminobutyric acid (gaba)a binding sites with [3h]muscimol, and serotoninergic binding sites with [3h]ketanserine. |
1998-09-25 |
2023-08-12 |
monkey |
| G Schmid, R Sala, G Bonanno, M Raiter. Neurosteroids may differentially affect the function of two native GABA(A) receptor subtypes in the rat brain. Naunyn-Schmiedeberg's archives of pharmacology. vol 357. issue 4. 1998-07-24. PMID:9606025. |
hippocampal noradrenergic and cerebellar glutamatergic axon terminals are known to possess gaba(a) receptors mediating, respectively, enhancement of noradrenaline (na) and glutamate release. |
1998-07-24 |
2023-08-12 |
rat |
| K Matsumoto, S Kohno, K Ojima, Y Tezuka, S Kadota, H Watanab. Effects of methylenechloride-soluble fraction of Japanese angelica root extract, ligustilide and butylidenephthalide, on pentobarbital sleep in group-housed and socially isolated mice. Life sciences. vol 62. issue 23. 1998-06-24. PMID:9627086. |
these results suggest the contribution of ligustilide and butylidenephthalide to the effect of jar-e on pb sleep in isolated mice, and implicate central noradrenergic and/or gaba(a) systems in the effects of these components. |
1998-06-24 |
2023-08-12 |
mouse |
| C H Jeng, Y Wan. Methamphetamine modulates GABA-induced electrophysiological depression by alternating noradrenergic actions in cerebellar Purkinje neurons. Psychopharmacology. vol 136. issue 2. 1998-06-18. PMID:9551769. |
taken together, these data suggest that ma may activate two noradrenergic modulatory mechanisms: beta-adrenergic receptor-induced gaba potentiation and alpha-adrenergic inhibition, which attenuates beta-mediated modulation. |
1998-06-18 |
2023-08-12 |
rat |
| Y Manunta, J M Edelin. Effects of noradrenaline on rate-level function of auditory cortex neurons: is there a "gating" effect of noradrenaline? Experimental brain research. vol 118. issue 3. 1998-04-14. PMID:9497143. |
however, for three cells the effect of gaba application was antagonized by bicuculline application, while on the same cells bicuculline application did not prevent the noradrenergic increase in threshold. |
1998-04-14 |
2023-08-12 |
Not clear |
| J P Kelly, A S Wrynn, B E Leonar. The olfactory bulbectomized rat as a model of depression: an update. Pharmacology & therapeutics. vol 74. issue 3. 1997-11-25. PMID:9352586. |
alterations in the noradrenergic, serotonergic, cholinergic, gamma-aminobutyric acid (gaba)ergic and glutamatergic neurotransmitter systems are also associated with olfactory bulbectomy. |
1997-11-25 |
2023-08-12 |
rat |
| A Pittaluga, A Bonfanti, M Raiter. Differential desensitization of ionotropic non-NMDA receptors having distinct neuronal location and function. Naunyn-Schmiedeberg's archives of pharmacology. vol 356. issue 1. 1997-09-05. PMID:9228187. |
to conclude: a) ionotropic non-nmda receptors mediating enhancement of na, 5-ht, ach, gaba and glutamate release exist on the corresponding nerve terminals; b) the receptors present on noradrenergic and serotonergic neurons are ampa-preferring receptors, whereas the glutamate autoreceptors resemble most the kainate-preferring subtype; the receptors mediating ach and gaba release can not be subclassified at present; c) desensitization may not be a property of all non-nmda ionotropic receptors. |
1997-09-05 |
2023-08-12 |
rat |
| K Matsumoto, S I Kohno, K Ojima, H Watanab. Flumazenil but not FG7142 reverses the decrease in pentobarbital sleep caused by activation of central noradrenergic systems in mice. Brain research. vol 754. issue 1-2. 1997-07-15. PMID:9134993. |
to determine whether the gaba(a)/benzodiazepine receptor system is involved in the decrease in pentobarbital sleep caused by activation of central noradrenergic systems, we examined in mice the effects of the benzodiazepine receptor ligands flumazenil and fg7142 on pentobarbital-induced sleep, and on adrenoceptor ligand modulation of pentobarbital sleep. |
1997-07-15 |
2023-08-12 |
mouse |
| R Patel, R Kerr, D J Maxwel. Absence of co-localized glutamic acid decarboxylase and neuropeptides in noradrenergic axons of the rat spinal cord. Brain research. vol 749. issue 1. 1997-06-10. PMID:9070645. |
none of the other peptides or glutamic acid decarboxylase were found to coexist at significant levels with dopamine beta-hydroxylase and hence it is likely that this group of neuropeptides and gaba are not co-transmitters of bulbospinal noradrenergic axons in the rat. |
1997-06-10 |
2023-08-12 |
rat |
| S Z Lange. 25 years since the discovery of presynaptic receptors: present knowledge and future perspectives. Trends in pharmacological sciences. vol 18. issue 3. 1997-06-09. PMID:9133779. |
the presynaptic inhibitory terminal autoreceptors were first described for noradrenergic neurones (alpha 2-adrenoceptors) and subsequently for other neurotransmitters: dopamine (d2/d3), acetylcholine (m2), gaba (gabab), histamine (h3) and serotonin (5-ht10). |
1997-06-09 |
2023-08-12 |
Not clear |
| B A Horger, R H Rot. The role of mesoprefrontal dopamine neurons in stress. Critical reviews in neurobiology. vol 10. issue 3-4. 1997-03-14. PMID:8978988. |
in addition, mesoprefrontal da neurons are uniquely modulated by a number of chemically distinct afferent influences including gamma-aminobutyric acid (gaba), serotonin, excitatory amino acid, substance p, opiate, and noradrenergic systems. |
1997-03-14 |
2023-08-12 |
Not clear |
| J E Cheun, H H Ye. Noradrenergic potentiation of cerebellar Purkinje cell responses to GABA: cyclic AMP as intracellular intermediary. Neuroscience. vol 74. issue 3. 1997-01-30. PMID:8884779. |
noradrenergic potentiation of cerebellar purkinje cell responses to gaba: cyclic amp as intracellular intermediary. |
1997-01-30 |
2023-08-12 |
rat |
| I Podkletnova, V Raevsky, H Alh. Reduction of GABAergic transmission and alterations in behavior after 6-OHDA treatment of rats. Brain research. Developmental brain research. vol 94. issue 2. 1996-12-20. PMID:8836579. |
we studied the effects of neonatal administration of 6-hydroxydopamine (6-ohda) upon gamma-aminobutyric acid (gaba) and noradrenergic neurotransmission in the developing rat brain. |
1996-12-20 |
2023-08-12 |
rat |
| P Branchereau, E J Van Bockstaele, J Chan, V M Picke. Pyramidal neurons in rat prefrontal cortex show a complex synaptic response to single electrical stimulation of the locus coeruleus region: evidence for antidromic activation and GABAergic inhibition using in vivo intracellular recording and electron microscopy. Synapse (New York, N.Y.). vol 22. issue 4. 1996-12-03. PMID:8867026. |
further insight into the chemical circuitry underlying these complex synaptic responses was provided by electron microscopic immunocytochemical analysis of the relations between the physiologically characterized neurons and either 1) gaba or 2) dopamine-beta-hydroxylase (dbh), a marker for noradrenergic terminals. |
1996-12-03 |
2023-08-12 |
rat |
| L Ferraro, S Tanganelli, L Marani, C Bianchi, L Beani, A Siniscalch. Evidence for an in vivo and in vitro modulation of endogenous cortical GABA release by alpha-glycerylphosphorylcholine. Neurochemical research. vol 21. issue 5. 1996-11-07. PMID:8726961. |
these results indicate that the facilitatory response by alpha-gpc on gaba release does not depend on a direct activation of either muscarinic or nicotinic receptors, but suggest the involvement of the noradrenergic system. |
1996-11-07 |
2023-08-12 |
rat |