| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M J Drus. Effects of maternal ethanol consumption of neurotransmitters and lipids in offspring. Neurobehavioral toxicology and teratology. vol 3. issue 2. 1981-09-15. PMID:6114445. |
in utero exposure to ethanol is reported to alter the steady-state levels, metabolism or release of catecholamines, octopamine, serotonin, glutamate, gaba, acetylcholine and histamine. |
1981-09-15 |
2023-08-12 |
rat |
| F Owen, A J Cross, T J Crow, R Lofthouse, M Poulte. Neurotransmitter receptors in brain in schizophrenia. Acta psychiatrica Scandinavica. Supplementum. vol 291. 1981-08-10. PMID:6113732. |
the binding of the dopamine agonist adtn and of ligands for the serotonin, muscarinic cholinergic, gaba, and benzodiazepine receptors was studied in 18 schizophrenic and 19 control brains. |
1981-08-10 |
2023-08-12 |
Not clear |
| S C Bondy, H A Tilson, A K Agrawa. Neurotransmitter receptors in brain regions of acrylamide- treated rats. II: Effects of extended exposure to acrylamide. Pharmacology, biochemistry, and behavior. vol 14. issue 4. 1981-07-20. PMID:6262843. |
at the highest dose (20 mg/kg, given ten times), increases were also found for frontal cortical serotonin, medullary glycine, and cerebellar gaba receptor sites. |
1981-07-20 |
2023-08-12 |
rat |
| R E Hruska, E K Silbergel. Inhibition of neurotransmitter receptor binding by ergot derivatives. Journal of neuroscience research. vol 6. issue 1. 1981-06-25. PMID:6111611. |
bromocriptine, lergotrile, lisuride, metergoline, and the sandoz ergot derivatives 25-397, 29-712, and 29-717 have been tested for their ability to inhibit the synaptic receptor binding of spiroperidol, 5-hydroxytryptamine (5-ht), d-lysergic acid diethylamide (lsd), quinuclidinyl benzilate (qnb), wb.4101, and gamma-aminobutyric acid (gaba). |
1981-06-25 |
2023-08-12 |
Not clear |
| J Davie. Selective depression of synaptic excitation in cat spinal neurones by baclofen: an iontophoretic study. British journal of pharmacology. vol 72. issue 2. 1981-06-13. PMID:7214103. |
6 comparison of baclofen with a number of other substances indicates that the depression of noncholinergic, excitatory, synaptic responses is unlikely to involve an interaction of this agent with receptors for monoamines, 5-hydroxytryptamine or the inhibitory amino acids, gamma-aminobutyric acid and glycine. |
1981-06-13 |
2023-08-12 |
cat |
| Y Nomur. [Functional development of the synaptic transmission in the rat CNS and its interaction with drugs (author's transl)]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. vol 76. issue 6. 1981-05-28. PMID:6259030. |
monoamine-stimulated activity of adenylate cyclase and specific binding of ligands in na(alpha 1, alpha 2, beta 1, beta 2), da, 5-ht, ach (muscarinic and nicotinic) and gaba receptors indicated dynamic changes through postnatal development. |
1981-05-28 |
2023-08-12 |
mouse |
| B Ault, R H Evans, A A Francis, D J Oakes, J C Watkin. Selective depression of excitatory amino acid induced depolarizations by magnesium ions in isolated spinal cord preparations. The Journal of physiology. vol 307. 1981-05-21. PMID:6259339. |
mg2+ did not depress motoneurone depolarization produced by 5-ht in the rat spinal cord or the depolarizing action of gaba on primary afferent terminals of the isolated frog spinal cord. |
1981-05-21 |
2023-08-12 |
rat |
| C M Forchetti, J L Mee. Evidence for a tonic GABAergic control of serotonin neurons in the median raphe nucleus. Brain research. vol 206. issue 1. 1981-05-13. PMID:7470888. |
we examined whether serotonin (5-ht)-containing neurons of the midbrain raphe nuclei are subject to an inhibitory control by gaba. |
1981-05-13 |
2023-08-12 |
human |
| D J Balfou. Effects of GABA and diazepam on 3H-serotonin release from hippocampal synaptosomes. European journal of pharmacology. vol 68. issue 1. 1981-03-17. PMID:7449830. |
the results suggest that 5-ht release in the hippocampus is under the presynaptic control of gaba and that diazepam may selectively enhance the inhibitory effect of gaba on the evoked release of 5-ht. |
1981-03-17 |
2023-08-12 |
rat |
| P Davies, R Katzman, R D Terr. Reduced somatostatin-like immunoreactivity in cerebral cortex from cases of Alzheimer disease and Alzheimer senile dementa. Nature. vol 288. issue 5788. 1981-01-26. PMID:6107862. |
despite numerous studies, there is no consistent evidence for the involvement of neurones releasing dopamine, noradrenaline, serotonin, or gamma-aminobutyric acid in ad/sdat, nor for loss of muscarinic cholinergic receptors. |
1981-01-26 |
2023-08-12 |
Not clear |
| C De Montigny, R Y Wang, T A Reader, G K Aghajania. Monoaminergic denervation of the rat hippocampus: microiontophoretic studies on pre- and postsynaptic supersensitivity to norepinephrine and serotonin. Brain research. vol 200. issue 2. 1980-12-18. PMID:6968237. |
the responsiveness of hippocampal ca3 pyramidal neurons to microiontophoretic applications of serotonin (5-ht), norepinephrine (ne), gamma-aminobutyric acid (gaba) and isoproterenol (iso) was assessed in rats following 5,7-dihydroxy-tryptamine (5,7-dht) and 6-hydroxydopamine (6-ohda) pretreatments and bilateral locus coeruleus lesions. |
1980-12-18 |
2023-08-12 |
rat |
| J M Baraban, G K Aghajania. Suppression of serotonergic neuronal firing by alpha-adrenoceptor antagonists: evidence against GABA mediation. European journal of pharmacology. vol 66. issue 4. 1980-12-16. PMID:6106551. |
the finding that systemic administration of picrotoxin, a gaba antagonist, partially reverses the suppression of 5-ht cells produced by systemic application of alpha-adrenoceptor antagonists led to the proposal that gaba interneurons located within the dorsal raphe mediate this suppression of 5-ht cell firing. |
1980-12-16 |
2023-08-12 |
Not clear |
| M Hershkowitz, H Szechtma. Pretreatment with delta 1-tetrahydrocannabinol and psychoactive drugs: effects on uptake of biogenic amines and on behavior. European journal of pharmacology. vol 59. issue 3-4. 1980-04-26. PMID:230975. |
injection of delta 1-tetrahydrocannabinol (thc) into mice increased the uptake into brain synaptosomes of radioactive da, ne, 5-ht and gaba, with the effect on gaba being the greatest; uptake of leucine was not stimulated, indicating that thc does not facilitate the transport of amino acids in general. |
1980-04-26 |
2023-08-11 |
mouse |
| A N Talalaenko, G K Krivobo. [Differences in hypothalamic monoaminergic mechanisms in heterogeneous conditioned reflexes in rats]. Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova. vol 29. issue 6. 1980-04-23. PMID:532342. |
local administration into the hypothalamus of gaba prolonged the latencies of heteromodal conditioned reflexes, whereas the serotonin had no effect on the recorded fr parameters, but facilitated ar significantly reducing its latencies. |
1980-04-23 |
2023-08-11 |
rat |
| R Y Wang, C de Montigny, B I Gold, R H Roth, G K Aghajania. Denervation supersensitivity to serotonin in rat forebrain: single cell studies. Brain research. vol 178. issue 2-3. 1980-02-15. PMID:509215. |
during the first 2 days after 5,7-dht, the enhanced sensitivity was selective for 5-ht; responses to d-lysergic acid diethylamide (lsd), norepinephrine (ne) and gamma-aminobutyric acid (gaba) were unchanged. |
1980-02-15 |
2023-08-11 |
rat |
| J E Freschi, A G Parfitt, W G Shai. Electrophysiology and pharmacology of striated muscle fibres cultured from dissociated neonatal rat pineal glands. The Journal of physiology. vol 293. 1980-01-24. PMID:501574. |
although the pineal gland has undetectable levels of ach, pineal muscle develops ach receptors but not noradrenaline, serotonin, melatonin, dopamine, or gaba receptors mediating electrophysiological responses, although these latter substances (except dopamine) are found in the pineal. |
1980-01-24 |
2023-08-11 |
rat |
| K Jellinger, P Riederer, P Kothbaue. Changes of some putative neurotransmitters in human cerebral infarction. Journal of neural transmission. Supplementum. issue 14. 1979-12-27. PMID:39976. |
dopamine (da), serotonin (5-ht), tryptophan (trp), 5-hydroxyindole acetic acid (5-hiaa), and gaba were assayed spectrofluorometrically in various regions of 16 human post-mortem brains with acute and old cerebral infarction. |
1979-12-27 |
2023-08-11 |
human |
| R W Kerwin, C J Pycoc. The effect of some putative neurotransmitters on the release of 5-hydroxytryptamine and gamma-aminobutyric acid from slices of the rat midbrain raphe area. Neuroscience. vol 4. issue 9. 1979-12-20. PMID:40162. |
the effect of some putative neurotransmitters on the release of 5-hydroxytryptamine and gamma-aminobutyric acid from slices of the rat midbrain raphe area. |
1979-12-20 |
2023-08-11 |
rat |
| L Edvinsson, D N Kraus. Pharmacological characterization of GABA receptors mediating vasodilation of verebral arteries in vitro. Brain research. vol 173. issue 1. 1979-12-20. PMID:226209. |
gaba (gamma-aminobutyric acid) produced a dose-dependent dilation of isolated cat and dog cerebral artery segments which had been given an active, tonic contraction by either prostaglandin f2 alpha or serotonin. |
1979-12-20 |
2023-08-11 |
human |
| E M Airaksine. Uptake of taurine, GABA, 5-HT, and dopamine by blood platelets in progressive myoclonus epilepsy. Epilepsia. vol 20. issue 5. 1979-11-29. PMID:38959. |
uptake of taurine, gaba, 5-ht, and dopamine by blood platelets in progressive myoclonus epilepsy. |
1979-11-29 |
2023-08-11 |
Not clear |