| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A L Frankhuyzen, A H Mulde. Release of radiolabeled dopamine, serotonin, acetylcholine and GABA from slices of rat striatum after intrastriatal kainic acid injections. Brain research. vol 135. issue 2. 1978-01-27. PMID:21721. |
release of radiolabeled dopamine, serotonin, acetylcholine and gaba from slices of rat striatum after intrastriatal kainic acid injections. |
1978-01-27 |
2023-08-11 |
rat |
| T Segawa, Y Nakata, H Yajima, K Kitagaw. Further observation on the lack of active uptake system for substance P in the central nervous system. Japanese journal of pharmacology. vol 27. issue 4. 1978-01-27. PMID:926460. |
crude mitochondrial p2 fractions from bovine hypothalamus and substantia nigra, slices from rabbit spinal cord and mesencephalon and glial fractions from rabbit brain were incubated with [3h]-substance p and the uptake was measured and compared with those for 5-ht and gaba. |
1978-01-27 |
2023-08-11 |
rabbit |
| Y Shirasawa, K Kokets. Action of 5-hydroxytryptamine on isolated spinal cord of bullfrogs. Japanese journal of pharmacology. vol 27. issue 1. 1977-07-29. PMID:194076. |
indeed, mephenesin, which is a selective blocker of polysynaptic transmission in the spinal cord, inhibited more markedly the 5-ht depolarization than the l-glutamate or gaba depolarization. |
1977-07-29 |
2023-08-11 |
Not clear |
| M F Belin, J C Kouyoumdjian, P Gonnard, M Jouve. [In vitro effect of serotonin on the enzyme activities of glutamate decarbosylase and GABA transaminase at the level of acellular preparations of rat mesencephalon synaptosomes]. Comptes rendus des seances de la Societe de biologie et de ses filiales. vol 170. issue 6. 1977-07-18. PMID:140743. |
[in vitro effect of serotonin on the enzyme activities of glutamate decarbosylase and gaba transaminase at the level of acellular preparations of rat mesencephalon synaptosomes]. |
1977-07-18 |
2023-08-11 |
rat |
| C G Honegger, L M Krepelka, M Steiner, H P von Hah. The effect of bovine myelin basic protein on uptake and release of H3-labelled 5-hydroxytryptamine, L-noradrenalin and gamma-aminobutyric acid in rat cortex slices. Experientia. vol 33. issue 3. 1977-06-30. PMID:67048. |
the effect of bovine myelin basic protein on uptake and release of h3-labelled 5-hydroxytryptamine, l-noradrenalin and gamma-aminobutyric acid in rat cortex slices. |
1977-06-30 |
2023-08-11 |
rat |
| B S Sastry, J W Philli. Metergoline as a selective 5-hydroxytryptamine antagonist in the cerebral cortex. Canadian journal of physiology and pharmacology. vol 55. issue 1. 1977-05-12. PMID:843988. |
in rats anaesthetized with a mixture of methoxyflurane, nitrous oxide, and oxygen, the depressant actions on the cerebral cortical neurones of iotophoretically applied 5-hydroxytryptamine (5-ht) but not of noradrenaline, histamine, amp ca2+, and gamma-aminobutyric acid were antagonized by metergoline. |
1977-05-12 |
2023-08-11 |
rat |
| S C Bondy, J L Purd. Development of neurotransmitter uptake in regions of the chick brain. Brain research. vol 119. issue 2. 1977-02-26. PMID:11872. |
the transport of low concentrations (around 10(-8) m) of gaba, glutamic acid, choline, dopamine and serotonin into homogenates was sodium and energy dependent and inhibited by a variety of pharmacological agents that are thought to act presynaptically. |
1977-02-26 |
2023-08-11 |
chicken |
| S C Bondy, J L Purd. Putative neurotransmitters of the avian visual pathway. Brain research. vol 119. issue 2. 1977-02-26. PMID:11873. |
embryonic enucleation resulted in severe reduction of development of the ability of the contralateral optic lobe to take up tritiated gaba, dopamine, choline, serotonin and glutamate from solutions around 10(-8)m. unilateral eye removal of new-hatched chicks caused failure of the denervated optic lobe to grow, but only the uptake capacity for glutamate was significantly recuced. |
1977-02-26 |
2023-08-11 |
chicken |
| D W Gallager, G K Aghajania. Effect of antipsychotic drugs on the firing of dorsal raphe cells. II. Reversal by picrotoxin. European journal of pharmacology. vol 39. issue 2. 1977-01-03. PMID:10174. |
based on these results, we propose that the adrenergic input may influence 5ht neurons indirectly via a gabaergic interneuron or interposed gaba neuron. |
1977-01-03 |
2023-08-11 |
Not clear |
| A R Green, A F Tordoff, M R Bloomfiel. Elevation of brain GABA concentrations with amino-oxyacetic acid; effect on the hyperactivity syndrome produced by increased 5-hydroxytryptamine synthesis in rats. Journal of neural transmission. vol 39. issue 1-2. 1976-12-30. PMID:988113. |
since a dopaminergic system has been shown to be involved in the 5-ht hyperactivity syndrome and appears to act post-synaptically to the 5-ht neurones initiating the syndrome it is suggested that inhibition of the 5-ht hyperactivity syndrome may be due to accumulation of gaba distal to the dopaminergic receptors. |
1976-12-30 |
2023-08-11 |
rat |
| G R Siggins, S J Henriksen, S C Landi. Electrophysiology of Purkinje neurons in the weaver mouse: iontophoresis of neurotransmitters and cyclic nucleotides, and stimulation of the nucleus locus coeruleus. Brain research. vol 114. issue 1. 1976-11-21. PMID:183862. |
iontophoresis of norepinephrine (ne), gaba and serotonin (5-ht) also uniformly depressed purkinje cell single spike activity in all normal and weaver mice; cyclic amp depressed 55% of normal and 70% of weaver purkinje cells. |
1976-11-21 |
2023-08-11 |
mouse |
| G R Siggins, S J Henriksen, S C Landi. Electrophysiology of Purkinje neurons in the weaver mouse: iontophoresis of neurotransmitters and cyclic nucleotides, and stimulation of the nucleus locus coeruleus. Brain research. vol 114. issue 1. 1976-11-21. PMID:183862. |
since several sites of indirect presynaptic actions are eliminated in weaver, our results further substantiate the direct post-synaptic inhibitory nature of gaba, 5-ht and ne, and the noradrenergic pathway from locus coeruleus to purkinje cells. |
1976-11-21 |
2023-08-11 |
mouse |
| A Dray, T J Gonye, N R Oakley, T Tanne. Evidence for the existence of a raphe projection to the substantia nigra in rat. Brain research. vol 113. issue 1. 1976-10-20. PMID:953733. |
discrete electrolytic lesions of the median raphe nucleus were followed by a decrease in 5-ht but not gaba concentrations in the substantia nigra. |
1976-10-20 |
2023-08-11 |
rat |
| L Bonkowski, W F Dryde. The effects of putative neurotransmitters on the resting membrane potential of dissociated brain neurones in culture. Brain research. vol 107. issue 1. 1976-08-02. PMID:5176. |
antagonism of the responses to acetylcholine, dopamine, serotonin and gaba was seen using atropine, pimozide, methysergide and bicuculline respectively. |
1976-08-02 |
2023-08-11 |
mouse |
| S J Enna, E D Bird, J P Bennett, D B Bylund, H I Yamamura, L L Iversen, S H Snyde. Huntington's chorea. Changes in neurotransmitter receptors in the brain. The New England journal of medicine. vol 294. issue 24. 1976-07-06. PMID:4733. |
neurotransmitter-receptor binding sites for apparent muscarinic cholinergic, beta-adrenergic, gamma-aminobutyric acid and serotonin receptors were measured in the caudate nucleus and frontal cerebral cortex from post-mortem brains of 16 patients with huntington's chorea and 16 controls. |
1976-07-06 |
2023-08-11 |
Not clear |
| R J Gullis, C E Row. The stimulation by synaptic transmitters of the incorporation of oleate into the phospholipid of synaptic membranes. The Biochemical journal. vol 148. issue 3. 1976-02-09. PMID:993. |
acetylcholine, carbamoylcholine, 5-hydroxytryptamine, dopamine, histamine and gamma-aminobutyric acid also stimulated the incorporation of oleate into choline glycerophospholipids of synaptic membranes. |
1976-02-09 |
2023-08-11 |
Not clear |
| F J Carmichael, Y Israe. Effects of ethanol on neurotransmitter release by rat brain cortical. The Journal of pharmacology and experimental therapeutics. vol 193. issue 3. 1975-11-01. PMID:239216. |
the order of sensitivity to ethanol was acetylcholine greater than serotonin greater than dopamine greater than norepinephrine greater than glutamate greater gamma-aminobutyric acid. |
1975-11-01 |
2023-08-11 |
rat |
| S P Banerjee, S H Snyder, R Mechoula. Cannabinoids: influence on neurotransmitter uptake in rat brain synaptosomes. The Journal of pharmacology and experimental therapeutics. vol 194. issue 1. 1975-10-30. PMID:168349. |
delta1-thc inhibits the accumulation of ne and 5-ht into hypothalamic preparations and da into the corpus striatum with ki values of about 12 to 25 mum while gaba uptake into cerebral cortical preparations is inhibited less (ki = 140 mum). |
1975-10-30 |
2023-08-11 |
rat |
| S P Banerjee, S H Snyder, R Mechoula. Cannabinoids: influence on neurotransmitter uptake in rat brain synaptosomes. The Journal of pharmacology and experimental therapeutics. vol 194. issue 1. 1975-10-30. PMID:168349. |
the affinities of delta6-thc, 7-hydroxy-delta1-thc, 7-hydroxy-delta6-thc and cannabidiol for 5-ht, ne and gaba transports are similar to values for delta1-thc, while cannabigerol, cannabinol and delta6-thc-7-oic acid have substantially less affinity. |
1975-10-30 |
2023-08-11 |
rat |
| A Philippu, H Matthae. Uptake of serotonin, gamma-aminobutyric acid and histamine into synaptic vesicles of the pig caudate nucleus. Naunyn-Schmiedeberg's archives of pharmacology. vol 287. issue 2. 1975-10-10. PMID:1143360. |
uptake of serotonin, gamma-aminobutyric acid and histamine into synaptic vesicles of the pig caudate nucleus. |
1975-10-10 |
2023-08-11 |
Not clear |