| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| P W Kalivas, P Duff. Repeated cocaine administration alters extracellular glutamate in the ventral tegmental area. Journal of neurochemistry. vol 70. issue 4. 1998-04-23. PMID:9523566. |
sch-23390 prevented the increase in extracellular glutamate associated with the acute administration of cocaine. |
1998-04-23 |
2023-08-12 |
human |
| P W Kalivas, P Duff. Repeated cocaine administration alters extracellular glutamate in the ventral tegmental area. Journal of neurochemistry. vol 70. issue 4. 1998-04-23. PMID:9523566. |
these data support the hypotheses that repeated cocaine administration produces an increase in the capacity of d1 receptor stimulation to release glutamate in the vta and that this mechanism partly mediates behavioral sensitization produced in rats treated with daily cocaine injections. |
1998-04-23 |
2023-08-12 |
human |
| R C Pierce, D C Reeder, J Hicks, Z R Morgan, P W Kaliva. Ibotenic acid lesions of the dorsal prefrontal cortex disrupt the expression of behavioral sensitization to cocaine. Neuroscience. vol 82. issue 4. 1998-03-26. PMID:9466434. |
the systemic injection of cocaine produced a significant increase in extracellular glutamate in the nucleus accumbens core among animals with a sham surgery; this effect was blocked by a bilateral lesion of the dorsal prefrontal cortex. |
1998-03-26 |
2023-08-12 |
rat |
| R C Pierce, D C Reeder, J Hicks, Z R Morgan, P W Kaliva. Ibotenic acid lesions of the dorsal prefrontal cortex disrupt the expression of behavioral sensitization to cocaine. Neuroscience. vol 82. issue 4. 1998-03-26. PMID:9466434. |
taken together, these results indicate that the dorsal prefrontal cortex, which provides excitatory amino acid input selectively to the core region of the nucleus accumbens, enhances the expression of behavioral sensitization to cocaine by increasing glutamate transmission in this subnucleus. |
1998-03-26 |
2023-08-12 |
rat |
| Y Li, A J Vartanian, F J White, C J Xue, M E Wol. Effects of the AMPA receptor antagonist NBQX on the development and expression of behavioral sensitization to cocaine and amphetamine. Psychopharmacology. vol 134. issue 3. 1998-02-26. PMID:9438676. |
we examined the effect of 2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo(f)quinoxaline (nbqx), an antagonist of the alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (ampa) subtype of glutamate receptor, on the development and expression of behavioral sensitization to amphetamine and cocaine in rats. |
1998-02-26 |
2023-08-12 |
rat |
| L Chang, C M Mehringer, T Ernst, R Melchor, H Myers, D Forney, P Sat. Neurochemical alterations in asymptomatic abstinent cocaine users: a proton magnetic resonance spectroscopy study. Biological psychiatry. vol 42. issue 12. 1998-02-10. PMID:9426880. |
n-acetyl-containing compounds (na), total creatine, choline-containing compounds, myo-inositol, and glutamate + glutamine were measured with in vivo proton magnetic resonance spectroscopy, vbr and wml were not significantly different in the cocaine users compared to the normal controls. |
1998-02-10 |
2023-08-12 |
human |
| M S Reid, K Hsu, S P Berge. Cocaine and amphetamine preferentially stimulate glutamate release in the limbic system: studies on the involvement of dopamine. Synapse (New York, N.Y.). vol 27. issue 2. 1997-10-21. PMID:9266771. |
cocaine and amphetamine preferentially stimulate glutamate release in the limbic system: studies on the involvement of dopamine. |
1997-10-21 |
2023-08-12 |
rat |
| M S Reid, K Hsu, S P Berge. Cocaine and amphetamine preferentially stimulate glutamate release in the limbic system: studies on the involvement of dopamine. Synapse (New York, N.Y.). vol 27. issue 2. 1997-10-21. PMID:9266771. |
the effects of cocaine and d-amphetamine on extracellular glutamate and aspartate levels in the nucleus accumbens, prefrontal cortex, and striatum were studied by in vivo microdialysis in awake, freely moving rats. |
1997-10-21 |
2023-08-12 |
rat |
| M S Reid, K Hsu, S P Berge. Cocaine and amphetamine preferentially stimulate glutamate release in the limbic system: studies on the involvement of dopamine. Synapse (New York, N.Y.). vol 27. issue 2. 1997-10-21. PMID:9266771. |
in the nucleus accumbens, glutamate levels were stimulated by cocaine (15-30 mg/kg, i.p. |
1997-10-21 |
2023-08-12 |
rat |
| M S Reid, K Hsu, S P Berge. Cocaine and amphetamine preferentially stimulate glutamate release in the limbic system: studies on the involvement of dopamine. Synapse (New York, N.Y.). vol 27. issue 2. 1997-10-21. PMID:9266771. |
the increase in nucleus accumbens glutamate levels following cocaine (30 mg/kg) was calcium-dependent and was blocked by pretreatment with dopamine antagonists; haloperidol (0.2 mg/kg, i.p. |
1997-10-21 |
2023-08-12 |
rat |
| M S Reid, K Hsu, S P Berge. Cocaine and amphetamine preferentially stimulate glutamate release in the limbic system: studies on the involvement of dopamine. Synapse (New York, N.Y.). vol 27. issue 2. 1997-10-21. PMID:9266771. |
in the prefrontal cortex, glutamate levels were stimulated by both cocaine (15-30 mg/kg, i.p.) |
1997-10-21 |
2023-08-12 |
rat |
| M S Reid, K Hsu, S P Berge. Cocaine and amphetamine preferentially stimulate glutamate release in the limbic system: studies on the involvement of dopamine. Synapse (New York, N.Y.). vol 27. issue 2. 1997-10-21. PMID:9266771. |
the increase in prefrontal cortex glutamate levels following cocaine (30 mg/kg) was calcium-dependent and was blocked by pretreatment with sch 23390 (0.02 mg/kg, i.p. |
1997-10-21 |
2023-08-12 |
rat |
| M S Reid, K Hsu, S P Berge. Cocaine and amphetamine preferentially stimulate glutamate release in the limbic system: studies on the involvement of dopamine. Synapse (New York, N.Y.). vol 27. issue 2. 1997-10-21. PMID:9266771. |
in the striatum, glutamate and aspartate levels were not affected by either cocaine (15-30 mg/kg, i.p.) |
1997-10-21 |
2023-08-12 |
rat |
| X F Zhang, X T Hu, F J White, M E Wol. Increased responsiveness of ventral tegmental area dopamine neurons to glutamate after repeated administration of cocaine or amphetamine is transient and selectively involves AMPA receptors. The Journal of pharmacology and experimental therapeutics. vol 281. issue 2. 1997-06-12. PMID:9152375. |
increased responsiveness of ventral tegmental area dopamine neurons to glutamate after repeated administration of cocaine or amphetamine is transient and selectively involves ampa receptors. |
1997-06-12 |
2023-08-12 |
rat |
| X F Zhang, X T Hu, F J White, M E Wol. Increased responsiveness of ventral tegmental area dopamine neurons to glutamate after repeated administration of cocaine or amphetamine is transient and selectively involves AMPA receptors. The Journal of pharmacology and experimental therapeutics. vol 281. issue 2. 1997-06-12. PMID:9152375. |
extracellular single cell recording and microiontophoresis were used to investigate possible alterations in the ability of glutamate agonists [(s)-alpha-amino-3- hydroxy-5-methyl-4-isoxazole propionate (ampa), n-methyl-d-aspartate (nmda), and (1s,3r)-1-aminocyclopentane-1,3-dicarboxylic acid (1s,3r-t-acpd)] to stimulate the firing of vta da neurons after 3 days of withdrawal from repeated administration of saline, cocaine or amphetamine. |
1997-06-12 |
2023-08-12 |
rat |
| Y Itzha. Attenuation of cocaine kindling by 7-nitroindazole, an inhibitor of brain nitric oxide synthase. Neuropharmacology. vol 35. issue 8. 1997-04-23. PMID:9121609. |
recent studies suggest the involvement of the n-methyl-d-aspartate (nmda) type of glutamate receptors and nitric oxide synthase (nos) in the process of increased sensitivity to the convulsive effect of cocaine ("cocaine kindling"). |
1997-04-23 |
2023-08-12 |
mouse |
| S E Robinson, P M Kunko, J A Smith, M J Wallace, Q Mo, J R Mahe. Extracellular aspartate concentration increases in nucleus accumbens after cocaine sensitization. European journal of pharmacology. vol 319. issue 1. 1997-04-14. PMID:9030894. |
involvement of excitatory amino acids in behavioral sensitization was assessed by comparing extracellular levels of aspartate and glutamate in the core of the nucleus accumbens in response to the first cocaine injection and the final cocaine challenge. |
1997-04-14 |
2023-08-12 |
rat |
| S E Robinson, P M Kunko, J A Smith, M J Wallace, Q Mo, J R Mahe. Extracellular aspartate concentration increases in nucleus accumbens after cocaine sensitization. European journal of pharmacology. vol 319. issue 1. 1997-04-14. PMID:9030894. |
increased nucleus accumbens extracellular concentration of aspartate, but not glutamate, was observed in rats exhibiting behavioral sensitization to cocaine. |
1997-04-14 |
2023-08-12 |
rat |
| K Bell, P W Kaliva. Context-specific cross-sensitization between systemic cocaine and intra-accumbens AMPA infusion in the rat. Psychopharmacology. vol 127. issue 4. 1997-03-25. PMID:8923575. |
two behavioral experiments were conducted in rats to evaluate the context-specificity of changes in nucleus accumbens glutamate transmission induced by systemic cocaine administration. |
1997-03-25 |
2023-08-12 |
human |
| K Bell, P W Kaliva. Context-specific cross-sensitization between systemic cocaine and intra-accumbens AMPA infusion in the rat. Psychopharmacology. vol 127. issue 4. 1997-03-25. PMID:8923575. |
at 2 weeks of withdrawal from daily cocaine injections (15 mg/kg, ip, daily x 7 days), subjects who had received cocaine in the test environment displayed a significantly greater motor response to intra-accumbens infusion of the glutamate receptor subtype-specific agonist, alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (ampa) than subjects who had received daily saline injections. |
1997-03-25 |
2023-08-12 |
human |