| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| G Sperk, H Lassmann, H Baran, S J Kish, F Seitelberger, O Hornykiewic. Kainic acid induced seizures: neurochemical and histopathological changes. Neuroscience. vol 10. issue 4. 1984-03-23. PMID:6141539. |
neurochemically, a selective decrease was seen in choline acetyltransferase activity (40%) of the amygdala/pyriform cortex area, and of glutamate decarboxylase activity in the dorsal hippocampus (45%) and amygdala/pyriform cortex (55%). |
1984-03-23 |
2023-08-12 |
rat |
| A C Foster, J F Collins, R Schwarc. On the excitotoxic properties of quinolinic acid, 2,3-piperidine dicarboxylic acids and structurally related compounds. Neuropharmacology. vol 22. issue 12A. 1984-03-14. PMID:6229703. |
none of the analogs tested were good inhibitors of cl--dependent or independent binding of l-[3h]glutamate, [3h]kainate or high-affinity, na+-dependent uptake of l-glutamate in striatal or hippocampal tissue at 1 mm. |
1984-03-14 |
2023-08-12 |
rat |
| E Hansso. Accumulation of putative amino acid neurotransmitters, monoamines and D-Ala2-Met-enkephalinamide in primary astroglial cultures from various brain areas, visualized by autoradiography. Brain research. vol 289. issue 1-2. 1984-03-12. PMID:6140983. |
the most prominent accumulation of grains was seen after incubating astroglial cultures from cerebral cortex, hippocampus and striatum with glutamate. |
1984-03-12 |
2023-08-12 |
Not clear |
| P Ferenci, S C Pappas, P J Munson, E A Jone. Changes in glutamate receptors on synaptic membranes associated with hepatic encephalopathy or hyperammonemia in the rabbit. Hepatology (Baltimore, Md.). vol 4. issue 1. 1984-03-12. PMID:6141134. |
data on the specific binding of glutamate to sm indicated that fulminant hepatic failure was associated with a decrease in the number of glutamate receptors on sm from cerebral cortex, cerebellum, and particularly the hippocampus, without any associated change in the affinity of these receptors. |
1984-03-12 |
2023-08-12 |
rabbit |
| P Ferenci, S C Pappas, P J Munson, E A Jone. Changes in glutamate receptors on synaptic membranes associated with hepatic encephalopathy or hyperammonemia in the rabbit. Hepatology (Baltimore, Md.). vol 4. issue 1. 1984-03-12. PMID:6141134. |
in contrast, hyperammonemia was associated with an increase in the affinity and no decrease in the number of glutamate receptors on sm from the hippocampus. |
1984-03-12 |
2023-08-12 |
rabbit |
| T M Mishunina, V Ia Kononenk. [Uptake of gamma-aminobutyric acid and glutamate decarboxylase activity in synaptosomes of various regions of the brain of rats in adrenalectomy and in subsequent hydrocortisone administration]. Ukrainskii biokhimicheskii zhurnal (1978). vol 55. issue 6. 1984-02-14. PMID:6659082. |
the adrenalectomy in rats followed by a single hydrocortisone administration had no influence on the glutamate decarboxylase activity and maximum rate of [3h] gaba uptake by synaptosomes of hypothalamus, hippocampus and cerebral hemispheres. |
1984-02-14 |
2023-08-12 |
rat |
| R Corradetti, G Moneti, F Moroni, G Pepeu, A Wieraszk. Electrical stimulation of the stratum radiatum increases the release and neosynthesis of aspartate, glutamate, and gamma-aminobutyric acid in rat hippocampal slices. Journal of neurochemistry. vol 41. issue 6. 1984-01-07. PMID:6139413. |
electrical stimulation of the stratum radiatum increases the release and neosynthesis of aspartate, glutamate, and gamma-aminobutyric acid in rat hippocampal slices. |
1984-01-07 |
2023-08-12 |
rat |
| E A Cavalheiro, M R de Feo, O Mecarelli, G F Ricc. Intracortical and intrahippocampal injections of kainic acid in developing rats: an electrographic study. Electroencephalography and clinical neurophysiology. vol 56. issue 5. 1983-12-17. PMID:6194966. |
the focal response seems to be correlated with a maturational process of glutamate and/or kainate receptors at both hippocampal and neocortical levels. |
1983-12-17 |
2023-08-12 |
rat |
| M Baudry, K Kramer, G Lync. Classification and properties of acidic amino acid receptors in hippocampus. III. Supersensitivity during the postnatal period and following denervation. Molecular pharmacology. vol 24. issue 2. 1983-10-28. PMID:6136903. |
partial denervation does not detectably change efflux elicited by d,l-homocysteic acid nor does it modify the properties of [3h]glutamate binding to hippocampal membranes. |
1983-10-28 |
2023-08-12 |
rat |
| M Baudry, K Kramer, L Fagni, M Recasens, G Lync. Classification and properties of acidic amino acid receptors in hippocampus. II. Biochemical studies using a sodium efflux assay. Molecular pharmacology. vol 24. issue 2. 1983-10-28. PMID:6310364. |
the order of potency of several excitatory amino acids on the stimulation of 22na efflux rate in hippocampal slices is highly correlated with their relative effects measured with electrophysiological techniques, but does not correlate with their relative potencies to inhibit [3h]glutamate binding to hippocampal membranes. |
1983-10-28 |
2023-08-12 |
Not clear |
| H Kaiya, K Takeuchi, H Yoshida, T Kondo, F Sanpei, Y Okada, M Namb. Effects of subchronic treatment of methamphetamine haloperidol on the rat brain levels of GABA, glutamate and aspartate. Folia psychiatrica et neurologica japonica. vol 37. issue 1. 1983-10-21. PMID:6136454. |
methamphetamine caused no statistically-significant changes in the gaba contents in any brain areas, a significant decrease in the glutamate content of the striatum, hippocampus and midbrain and an increase in the aspartate content of the hypothalamus. |
1983-10-21 |
2023-08-12 |
rat |
| M Baudry, K Kramer, G Lync. Irreversibility and time course of calcium stimulated [3H]glutamate binding to rat hippocampal membranes. Brain research. vol 270. issue 1. 1983-09-23. PMID:6307485. |
irreversibility and time course of calcium stimulated [3h]glutamate binding to rat hippocampal membranes. |
1983-09-23 |
2023-08-12 |
rat |
| M Baudry, K Kramer, G Lync. Irreversibility and time course of calcium stimulated [3H]glutamate binding to rat hippocampal membranes. Brain research. vol 270. issue 1. 1983-09-23. PMID:6307485. |
previous studies have indicated that calcium ions induce an irreversible increase of [3h]glutamate binding to rat hippocampal membranes. |
1983-09-23 |
2023-08-12 |
rat |
| M Baudry, K Kramer, G Lync. Irreversibility and time course of calcium stimulated [3H]glutamate binding to rat hippocampal membranes. Brain research. vol 270. issue 1. 1983-09-23. PMID:6307485. |
the calcium chelator egta and the proteinase inhibitor leupeptin were introduced at various times during the incubation of hippocampal membranes with calcium and the binding of [3h]glutamate subsequently assayed. |
1983-09-23 |
2023-08-12 |
rat |
| M Baudry, R Siman, E K Smith, G Lync. Regulation by calcium ions of glutamate receptor binding in hippocampal slices. European journal of pharmacology. vol 90. issue 2-3. 1983-09-23. PMID:6307724. |
regulation by calcium ions of glutamate receptor binding in hippocampal slices. |
1983-09-23 |
2023-08-12 |
Not clear |
| M Baudry, R Siman, E K Smith, G Lync. Regulation by calcium ions of glutamate receptor binding in hippocampal slices. European journal of pharmacology. vol 90. issue 2-3. 1983-09-23. PMID:6307724. |
hippocampal slices were incubated in a krebs-bicarbonate buffer with various concentrations of calcium and [3h]glutamate receptor binding was measured in crude synaptic membranes derived from these slices. |
1983-09-23 |
2023-08-12 |
Not clear |
| M Baudry, R Siman, E K Smith, G Lync. Regulation by calcium ions of glutamate receptor binding in hippocampal slices. European journal of pharmacology. vol 90. issue 2-3. 1983-09-23. PMID:6307724. |
these results indicate that the same calcium-dependent processes which were previously shown to regulate [ 3h ]glutamate receptor binding to hippocampal membranes occur in the hippocampal slice preparation, and they suggest a mechanism by which fluctuations in calcium levels can activate a calcium-dependent proteinase, the degradation of cytoskeletal-associated proteins and the unmasking of additional glutamate receptors. |
1983-09-23 |
2023-08-12 |
Not clear |
| P J Richardso. Presynaptic distribution of the cholinergic-specific antigen Chol-1 and 5'-nucleotidase in rat brain, as determined by complement-mediated release of neurotransmitters. Journal of neurochemistry. vol 41. issue 3. 1983-09-23. PMID:6308166. |
nerve terminals prepared from rat cortex and hippocampus were loaded with seven radioactive putative neurotransmitters (serotonin, noradrenaline, dopamine, gamma-aminobutyric acid, aspartate, glutamate, and taurine). |
1983-09-23 |
2023-08-12 |
rat |
| J W Olney, T deGubareff, R S Slovite. "Epileptic" brain damage in rats induced by sustained electrical stimulation of the perforant path. II. Ultrastructural analysis of acute hippocampal pathology. Brain research bulletin. vol 10. issue 5. 1983-09-23. PMID:6871738. |
it is proposed, therefore, that sustained electrical stimulation of the perforant path results in excessive synaptic release and accumulation of glutamate (or aspartate) at numerous dendrosomal receptors in the hippocampus with consequent degeneration of the dendrosomal structures housing these receptors. |
1983-09-23 |
2023-08-12 |
rat |
| M N Perkins, T W Ston. Pharmacology and regional variations of quinolinic acid-evoked excitations in the rat central nervous system. The Journal of pharmacology and experimental therapeutics. vol 226. issue 2. 1983-09-20. PMID:6308211. |
neurons in the spinal cord and cerebellum were largely unresponsive to quinolinate, whereas cells in the neocortex, striatum and hippocampus responded to this agonist to a similar degree as glutamate. |
1983-09-20 |
2023-08-12 |
rat |