All Relations between glutamate and medial prefrontal cortex

Publication Sentence Publish Date Extraction Date Species
Morten Grupe, Giovanna Paolone, Anders A Jensen, Karin Sandager-Nielsen, Martin Sarter, Morten Grunne. Selective potentiation of (α4)3(β2)2 nicotinic acetylcholine receptors augments amplitudes of prefrontal acetylcholine- and nicotine-evoked glutamatergic transients in rats. Biochemical pharmacology. vol 86. issue 10. 2013-12-23. PMID:24051136. in the present study we employed glutamate-sensitive microelectrodes and the (α4)3(β2)2-selective positive allosteric modulator (pam) ns9283 to investigate the importance of the ls α4β2 nachr for glutamate release in the rat medial prefrontal cortex (mpfc). 2013-12-23 2023-08-12 rat
Don A Davies, Quentin Greba, John G Howlan. GluN2B-containing NMDA receptors and AMPA receptors in medial prefrontal cortex are necessary for odor span in rats. Frontiers in behavioral neuroscience. vol 7. 2013-12-18. PMID:24348356. our aim was to examine the role of the n-methyl-d-aspartate (nmda) and α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (ampa) glutamate receptors in odor span capacity using systemic injections or infusions of receptor antagonists into the medial prefrontal cortex (mpfc). 2013-12-18 2023-08-12 rat
Niall W Duncan, Christine Wiebking, Brice Tiret, Malgorzata Marjańska, Malgoranza Marjańska, Dave J Hayes, Oliver Lyttleton, Julien Doyon, Georg Northof. Glutamate concentration in the medial prefrontal cortex predicts resting-state cortical-subcortical functional connectivity in humans. PloS one. vol 8. issue 4. 2013-10-22. PMID:23573246. glutamate concentration in the medial prefrontal cortex predicts resting-state cortical-subcortical functional connectivity in humans. 2013-10-22 2023-08-12 Not clear
Niall W Duncan, Christine Wiebking, Brice Tiret, Malgorzata Marjańska, Malgoranza Marjańska, Dave J Hayes, Oliver Lyttleton, Julien Doyon, Georg Northof. Glutamate concentration in the medial prefrontal cortex predicts resting-state cortical-subcortical functional connectivity in humans. PloS one. vol 8. issue 4. 2013-10-22. PMID:23573246. to investigate the role of glutamate in individual differences in communication between the cortex--specifically the medial prefrontal cortex (mpfc)--and subcortical regions in humans, a combination of resting-state fmri, dti and mrs was performed. 2013-10-22 2023-08-12 Not clear
Livio Luongo, Vito de Novellis, Luisa Gatta, Enza Palazzo, Daniela Vita, Francesca Guida, Catia Giordano, Dario Siniscalco, Ida Marabese, Maria De Chiaro, Serena Boccella, Francesca Rossi, Sabatino Maion. Role of metabotropic glutamate receptor 1 in the basolateral amygdala-driven prefrontal cortical deactivation in inflammatory pain in the rat. Neuropharmacology. vol 66. 2013-07-02. PMID:22796105. we have here investigated the role of group i metabotropic glutamate receptors (mglurs) in the basolateral amygdala (bla) pre-infra-limbic (pl-il) divisions of the medial prefrontal cortex (mpfc) neuron connections after carrageenan-induced inflammatory pain in the rat. 2013-07-02 2023-08-12 rat
Helen B Simpson, Dikoma C Shungu, James Bender, Xiangling Mao, Xiaoyan Xu, Mark Slifstein, Lawrence S Kegele. Investigation of cortical glutamate-glutamine and γ-aminobutyric acid in obsessive-compulsive disorder by proton magnetic resonance spectroscopy. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 37. issue 12. 2013-03-22. PMID:22850733. we used proton magnetic resonance spectroscopy (¹h mrs) to test our hypothesis that unmedicated adults with ocd have reduced glutamate plus glutamine (glx) levels in the medial prefrontal cortex (mpfc) compared with healthy controls. 2013-03-22 2023-08-12 human
Alyssa M McEwen, Denee T A Burgess, Christopher C Hanstock, Peter Seres, Panteha Khalili, Stephen C Newman, Glen B Baker, Nicholas D Mitchell, Janisse Khudabux-Der, Peter S Allen, Jean-Michel LeMelled. Increased glutamate levels in the medial prefrontal cortex in patients with postpartum depression. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 37. issue 11. 2013-02-26. PMID:22805604. increased glutamate levels in the medial prefrontal cortex in patients with postpartum depression. 2013-02-26 2023-08-12 Not clear
Alyssa M McEwen, Denee T A Burgess, Christopher C Hanstock, Peter Seres, Panteha Khalili, Stephen C Newman, Glen B Baker, Nicholas D Mitchell, Janisse Khudabux-Der, Peter S Allen, Jean-Michel LeMelled. Increased glutamate levels in the medial prefrontal cortex in patients with postpartum depression. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 37. issue 11. 2013-02-26. PMID:22805604. the medial prefrontal cortex (mpfc) is a key brain area in depressive symptomatology; specifically, glutamate (glu) has been reported to play a significant role in major depression (md) in this area. 2013-02-26 2023-08-12 Not clear
Osnat M Ben-Shahar, Karen K Szumlinski, Kevin D Lominac, Ami Cohen, Evan Gordon, Kyle L Ploense, Jeremy DeMartini, Nicholas Bernstein, Nicole M Rudy, Ahmad N Nabhan, Arianne Sacramento, Kelly Pagano, Giovanni A Carosso, Nick Woodwar. Extended access to cocaine self-administration results in reduced glutamate function within the medial prefrontal cortex. Addiction biology. vol 17. issue 4. 2012-10-01. PMID:22339852. extended access to cocaine self-administration results in reduced glutamate function within the medial prefrontal cortex. 2012-10-01 2023-08-12 human
Jia Qi, Wen-Yan Han, Jing-Yu Yang, Li-Hui Wang, Ying-Xu Dong, Fang Wang, Ming Song, Chun-Fu W. Oxytocin regulates changes of extracellular glutamate and GABA levels induced by methamphetamine in the mouse brain. Addiction biology. vol 17. issue 4. 2012-10-01. PMID:22507692. in the present study, we investigated the effects of ot on extracellular levels of glutamate (glu) and γ-aminobutyric acid (gaba) induced by methamphetamine (map) in the medial prefrontal cortex (mpfc) and dorsal hippocampus (dhc) of freely moving mice, using in vivo microdialysis coupled to high-performance liquid chromatography and fluorescence detection. 2012-10-01 2023-08-12 mouse
Kristin M Timmer, Jeffery D Stekete. Examination of a role for metabotropic glutamate receptor 5 in the medial prefrontal cortex in cocaine sensitization in rats. Psychopharmacology. vol 221. issue 1. 2012-09-25. PMID:22147256. examination of a role for metabotropic glutamate receptor 5 in the medial prefrontal cortex in cocaine sensitization in rats. 2012-09-25 2023-08-12 rat
Daiying Zuo, Tomasz Bzdega, Rafal T Olszewski, John R Moffett, Joseph H Neal. Effects of N-acetylaspartylglutamate (NAAG) peptidase inhibition on release of glutamate and dopamine in prefrontal cortex and nucleus accumbens in phencyclidine model of schizophrenia. The Journal of biological chemistry. vol 287. issue 26. 2012-09-20. PMID:22570482. pcp also increases glutamate and dopamine release in the medial prefrontal cortex and nucleus accumbens, brain regions associated with expression of psychosis. 2012-09-20 2023-08-12 Not clear
Daiying Zuo, Tomasz Bzdega, Rafal T Olszewski, John R Moffett, Joseph H Neal. Effects of N-acetylaspartylglutamate (NAAG) peptidase inhibition on release of glutamate and dopamine in prefrontal cortex and nucleus accumbens in phencyclidine model of schizophrenia. The Journal of biological chemistry. vol 287. issue 26. 2012-09-20. PMID:22570482. this research tested the hypothesis that two structurally distinct naag peptidase inhibitors, zj43 and 2-(phosphonomethyl)pentane-1,5-dioic acid, would elevate levels of synaptically released naag and reduce pcp-induced increases in glutamate and dopamine levels in the medial prefrontal cortex and nucleus accumbens. 2012-09-20 2023-08-12 Not clear
Osama A Abulseoud, Joseph D Miller, Jinhua Wu, Doo-Sup Choi, Daniel P Holschneide. Ceftriaxone upregulates the glutamate transporter in medial prefrontal cortex and blocks reinstatement of methamphetamine seeking in a condition place preference paradigm. Brain research. vol 1456. 2012-08-23. PMID:22521042. ceftriaxone upregulates the glutamate transporter in medial prefrontal cortex and blocks reinstatement of methamphetamine seeking in a condition place preference paradigm. 2012-08-23 2023-08-12 human
F A Moreira, D C Aguiar, L B Resstel, S F Lisboa, A C Campos, F V Gomes, F S Guimarãe. Neuroanatomical substrates involved in cannabinoid modulation of defensive responses. Journal of psychopharmacology (Oxford, England). vol 26. issue 1. 2012-08-21. PMID:21616976. the present review summarizes recent data suggesting that they involve modulation of glutamate and gaba-mediated neurotransmission in brain sites such as the medial prefrontal cortex, amygdaloid complex, bed nucleus of the stria terminalis, hippocampus and dorsal periaqueductal gray. 2012-08-21 2023-08-12 Not clear
Jennifer M Bossert, Anna L Stern, Florence R M Theberge, Nathan J Marchant, Hui-Ling Wang, Marisela Morales, Yavin Shaha. Role of projections from ventral medial prefrontal cortex to nucleus accumbens shell in context-induced reinstatement of heroin seeking. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 14. 2012-05-29. PMID:22492053. this effect is attenuated by inhibition of glutamate or dopamine transmission in nucleus accumbens shell, or inactivation of ventral medial prefrontal cortex (mpfc). 2012-05-29 2023-08-12 rat
Shane A Perrine, Shonagh K O'Leary-Moore, Matthew P Galloway, John H Hannigan, Scott E Bowe. Binge toluene exposure alters glutamate, glutamine and GABA in the adolescent rat brain as measured by proton magnetic resonance spectroscopy. Drug and alcohol dependence. vol 115. issue 1-2. 2012-03-07. PMID:21126832. adolescent male sprague-dawley rats were exposed to toluene (0, 8000, or 12,000 ppm) for 15 min twice daily from postnatal day 28 (p28) through p34 and then euthanized either 1 or 7 days later (on p35 or p42) to assess glutamate (glu), glutamine, and gaba levels in intact tissue punches from the medial prefrontal cortex (mpfc), anterior striatum and hippocampus. 2012-03-07 2023-08-12 rat
Anna R Moore, Wen-Liang Zhou, Evgeniy S Potapenko, Eun-Ji Kim, Srdjan D Anti. Brief dopaminergic stimulations produce transient physiological changes in prefrontal pyramidal neurons. Brain research. vol 1370. 2011-11-23. PMID:21059342. here we apply short (2s) iontophoretic pulses of glutamate, gaba, dopamine and dopaminergic agonists locally, onto layer 5 pyramidal neurons in brain slices of the rat medial prefrontal cortex (pfc). 2011-11-23 2023-08-12 rat
Kun Liu, Jeffery D Stekete. Repeated exposure to cocaine alters medial prefrontal cortex dopamine D₂-like receptor modulation of glutamate and dopamine neurotransmission within the mesocorticolimbic system. Journal of neurochemistry. vol 119. issue 2. 2011-11-15. PMID:21692802. repeated exposure to cocaine alters medial prefrontal cortex dopamine d₂-like receptor modulation of glutamate and dopamine neurotransmission within the mesocorticolimbic system. 2011-11-15 2023-08-12 rat
Kun Liu, Jeffery D Stekete. Repeated exposure to cocaine alters medial prefrontal cortex dopamine D₂-like receptor modulation of glutamate and dopamine neurotransmission within the mesocorticolimbic system. Journal of neurochemistry. vol 119. issue 2. 2011-11-15. PMID:21692802. infusion of quinpirole (0.01, 1.0 and 100 μm), a d₂-like receptor agonist, into the medial prefrontal cortex produced a dose-dependent decrease in cortical, nucleus accumbens and ventral tegmental area extracellular glutamate levels in control but not sensitized animals. 2011-11-15 2023-08-12 rat