| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Merighi, J M Polak, D T Theodosi. Ultrastructural visualization of glutamate and aspartate immunoreactivities in the rat dorsal horn, with special reference to the co-localization of glutamate, substance P and calcitonin-gene related peptide. Neuroscience. vol 40. issue 1. 1991-07-22. PMID:1711177. |
our observations demonstrate that there is an abundant glutamate immunoreactivity in the superficial layers of the rat dorsal horn, localized in neuronal profiles distinct from those containing aspartate or gaba. |
1991-07-22 |
2023-08-11 |
rat |
| M Randić, H Hećimović, P D Ry. Substance P modulates glutamate-induced currents in acutely isolated rat spinal dorsal horn neurones. Neuroscience letters. vol 117. issue 1-2. 1991-04-01. PMID:1705317. |
since glutamate activates both n-methyl-d-aspartate (nmda) and non-nmda receptors in rat dorsal horn neurons, selective agonists, kainate, quisqualate, alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid (ampa) and nmda were used to determine which subtype of excitatory amino acid receptors interacted with sp. |
1991-04-01 |
2023-08-11 |
rat |
| E Carstens, M Hartung, B Stelzer, M Zimmerman. Suppression of a hind limb flexion withdrawal reflex by microinjection of glutamate or morphine into the periaqueductal gray in the rat. Pain. vol 43. issue 1. 1991-03-05. PMID:1980535. |
microinjection into the midbrain periaqueductal gray (pag) or lateral reticular formation (lrf) of the neuronal excitant glutamate produces analgesia, and suppresses the responses of a fraction of spinal dorsal horn neurons to noxious heat applied to ventral hind paw skin. |
1991-03-05 |
2023-08-11 |
rat |
| E Carstens, M Hartung, B Stelzer, M Zimmerman. Suppression of a hind limb flexion withdrawal reflex by microinjection of glutamate or morphine into the periaqueductal gray in the rat. Pain. vol 43. issue 1. 1991-03-05. PMID:1980535. |
in anesthetized rats, we tested whether (a) glutamate microinjections into pag or lrf, and (b) morphine microinjections into pag, affected the isometric force of hind limb withdrawal elicited by the same noxious heat stimuli on the hind paw as used in single-unit studies of dorsal horn neurons. |
1991-03-05 |
2023-08-11 |
rat |
| I Kangrga, M Randi. Tachykinins and calcitonin gene-related peptide enhance release of endogenous glutamate and aspartate from the rat spinal dorsal horn slice. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 10. issue 6. 1990-07-26. PMID:1693954. |
tachykinins and calcitonin gene-related peptide enhance release of endogenous glutamate and aspartate from the rat spinal dorsal horn slice. |
1990-07-26 |
2023-08-11 |
rat |
| I Kangrga, J S Larew, M Randi. The effects of substance P and calcitonin gene-related peptide on the efflux of endogenous glutamate and aspartate from the rat spinal dorsal horn in vitro. Neuroscience letters. vol 108. issue 1-2. 1990-03-19. PMID:1689473. |
the effects of substance p and calcitonin gene-related peptide on the efflux of endogenous glutamate and aspartate from the rat spinal dorsal horn in vitro. |
1990-03-19 |
2023-08-11 |
rat |
| K L Jansen, R L Faull, M Dragunow, H Waldvoge. Autoradiographic localisation of NMDA, quisqualate and kainic acid receptors in human spinal cord. Neuroscience letters. vol 108. issue 1-2. 1990-03-19. PMID:1689476. |
all of the receptor types, and sp, were concentrated in lamina ii of the dorsal horn, consistent with physiological data indicating that glutamate is a neurotransmitter of primary afferent terminals in the spinal cord. |
1990-03-19 |
2023-08-11 |
human |
| S F Morrison, J Callaway, T A Milner, D J Rei. Glutamate in the spinal sympathetic intermediolateral nucleus: localization by light and electron microscopy. Brain research. vol 503. issue 1. 1990-03-14. PMID:2575434. |
glutamate immunoreactivity in the iml was eliminated caudal to t3 spinal transection, while that in the dorsal horn was preserved. |
1990-03-14 |
2023-08-11 |
cattle |
| G Gerber, I Kangrga, P D Ryu, J S Larew, M Randi. Multiple effects of phorbol esters in the rat spinal dorsal horn. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 9. issue 10. 1989-11-14. PMID:2571684. |
spinal cord slice preparation and intracellular recording techniques were used to examine the effects of phorbol esters on the sodium- and calcium-dependent action potentials, the excitatory synaptic transmission, the basal (resting) and the dorsal root stimulation-evoked release of 9 endogenous amino acids, including glutamate and aspartate, and the responsiveness of the rat dorsal horn neurons to excitatory amino acids (glutamic, kainic, quisqualic, and n-methyl-d-aspartic). |
1989-11-14 |
2023-08-11 |
rat |
| G Gerber, I Kangrga, P D Ryu, J S Larew, M Randi. Multiple effects of phorbol esters in the rat spinal dorsal horn. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 9. issue 10. 1989-11-14. PMID:2571684. |
phorbol esters could potentiate excitatory synaptic transmission by acting predominantly at a postsynaptic site (nmda receptor), since the duration of the increased responsiveness of dorsal horn neurons to glutamate and nmda correlates better with the enhancement of epsps than with the increased release of the stimulation-evoked glutamate and aspartate. |
1989-11-14 |
2023-08-11 |
rat |
| E Carstens, B Stelzer, M Zimmerman. Microinjections of glutamate or morphine at coincident midbrain sites have different effects on nociceptive dorsal horn neurons in the rat. Neuroscience letters. vol 95. issue 1-3. 1989-03-29. PMID:2906415. |
microinjections of glutamate or morphine at coincident midbrain sites have different effects on nociceptive dorsal horn neurons in the rat. |
1989-03-29 |
2023-08-11 |
rat |
| S De Biasi, A Rustion. Glutamate and substance P coexist in primary afferent terminals in the superficial laminae of spinal cord. Proceedings of the National Academy of Sciences of the United States of America. vol 85. issue 20. 1988-11-21. PMID:2459717. |
effects of glutamate and substance p on spinal dorsal horn neurons may result from co-release of these two mediators from the same dorsal root afferent terminal. |
1988-11-21 |
2023-08-11 |
rat |
| K E Miller, J R Clements, A A Larson, A J Beit. Organization of glutamate-like immunoreactivity in the rat superficial dorsal horn: light and electron microscopic observations. Synapse (New York, N.Y.). vol 2. issue 1. 1988-10-27. PMID:2901792. |
glutamate has been shown to be a neurotransmitter in the central nervous system of vertebrates, and it has been hypothesized that glutamate is functional as a neurotransmitter in the spinal cord dorsal horn. |
1988-10-27 |
2023-08-11 |
rat |
| K E Miller, J R Clements, A A Larson, A J Beit. Organization of glutamate-like immunoreactivity in the rat superficial dorsal horn: light and electron microscopic observations. Synapse (New York, N.Y.). vol 2. issue 1. 1988-10-27. PMID:2901792. |
a monoclonal antibody to fixative-modified glutamate was used in this study to examine the light microscopic and ultrastructural profiles of glutamate-like immunoreactivity in the superficial dorsal horn of the rat spinal cord. |
1988-10-27 |
2023-08-11 |
rat |
| S P Schneider, E R Per. Comparison of primary afferent and glutamate excitation of neurons in the mammalian spinal dorsal horn. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 8. issue 6. 1988-08-03. PMID:2898513. |
comparison of primary afferent and glutamate excitation of neurons in the mammalian spinal dorsal horn. |
1988-08-03 |
2023-08-11 |
Not clear |
| S P Schneider, E R Per. Selective excitation of neurons in the mammalian spinal dorsal horn by aspartate and glutamate in vitro: correlation with location and excitatory input. Brain research. vol 360. issue 1-2. 1986-02-14. PMID:2866826. |
selective excitation of neurons in the mammalian spinal dorsal horn by aspartate and glutamate in vitro: correlation with location and excitatory input. |
1986-02-14 |
2023-08-11 |
Not clear |
| S P Schneider, E R Per. Selective excitation of neurons in the mammalian spinal dorsal horn by aspartate and glutamate in vitro: correlation with location and excitatory input. Brain research. vol 360. issue 1-2. 1986-02-14. PMID:2866826. |
these findings are consistent with the idea that aspartate or glutamate may function as a synaptic mediator for some neurons terminating in the superficial dorsal horn. |
1986-02-14 |
2023-08-11 |
Not clear |
| C E Jahr, T M Jessel. Synaptic transmission between dorsal root ganglion and dorsal horn neurons in culture: antagonism of monosynaptic excitatory postsynaptic potentials and glutamate excitation by kynurenate. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 5. issue 8. 1985-09-19. PMID:2862229. |
synaptic transmission between dorsal root ganglion and dorsal horn neurons in culture: antagonism of monosynaptic excitatory postsynaptic potentials and glutamate excitation by kynurenate. |
1985-09-19 |
2023-08-11 |
rat |
| K Fuji, E Senba, S Fujii, I Nomura, J Y Wu, Y Ueda, M Tohyam. Distribution, ontogeny and projections of cholecystokinin-8, vasoactive intestinal polypeptide and gamma-aminobutyrate-containing neuron systems in the rat spinal cord: an immunohistochemical analysis. Neuroscience. vol 14. issue 3. 1985-06-14. PMID:3887208. |
immunoreactive fibers to cholecystokinin-8, vasoactive intestinal polypeptide and glutamate decarboxylase (gamma-aminobutyrate-synthesizing enzyme, used as a marker of gamma-aminobutyrate) were widely distributed in the spinal cord, being particularly concentrated in the superficial dorsal horn, suggesting a close relationship to the pain transmission system. |
1985-06-14 |
2023-08-11 |
rat |
| J Millar, M Armstrong-Jame. The responses of neurones of the superficial dorsal horn to ionophoretically applied glutamate ion. Brain research. vol 231. issue 2. 1982-04-12. PMID:6120023. |
the responses of neurones of the superficial dorsal horn to ionophoretically applied glutamate ion. |
1982-04-12 |
2023-08-12 |
cat |