| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Ueda, K Sugimoto, T Oyama, Y Kuraishi, M Sato. Opioidergic inhibition of capsaicin-evoked release of glutamate from rat spinal dorsal horn slices. Neuropharmacology. vol 34. issue 3. 1995-09-01. PMID:7630485. |
these results suggest that mu-, and delta-opioid agonists modulate pain transmission in the spinal dorsal horn, at least in part, by inhibiting the release of glutamate from capsaicin-sensitive primary afferents. |
1995-09-01 |
2023-08-12 |
rat |
| M Ueda, T Oyama, Y Kuraishi, A Akaike, M Sato. Alpha 2-adrenoceptor-mediated inhibition of capsaicin-evoked release of glutamate from rat spinal dorsal horn slices. Neuroscience letters. vol 188. issue 2. 1995-07-27. PMID:7792058. |
alpha 2-adrenoceptor-mediated inhibition of capsaicin-evoked release of glutamate from rat spinal dorsal horn slices. |
1995-07-27 |
2023-08-12 |
rat |
| M Ueda, T Oyama, Y Kuraishi, A Akaike, M Sato. Alpha 2-adrenoceptor-mediated inhibition of capsaicin-evoked release of glutamate from rat spinal dorsal horn slices. Neuroscience letters. vol 188. issue 2. 1995-07-27. PMID:7792058. |
to determine whether noradrenaline-alpha-adrenoceptor systems exert inhibitory influence on the release of glutamate from the nociceptive primary afferents, the effects of alpha-adrenoceptor agonists on the capsaicin (3 microm)-evoked release of glutamate from rat spinal dorsal horn slices were examined using an on-line continuous monitoring system for glutamate. |
1995-07-27 |
2023-08-12 |
rat |
| K Okano, Y Kuraishi, M Sato. Effects of intrathecally injected glutamate and substance P antagonists on repeated cold stress-induced hyperalgesia in rats. Biological & pharmaceutical bulletin. vol 18. issue 1. 1995-06-07. PMID:7537576. |
to determine the role of nk-1 substance p receptors and n-methyl-d-aspartate (nmda) and non-nmda glutamate receptors in the spinal dorsal horn in the hyperalgesia induced by repeated cold stress (rcs), we examined the effects of intrathecal injections of antagonists to nk-1, nmda and non-nmda receptors on the nociceptive threshold of rcs rats for paw-pressure stimulation. |
1995-06-07 |
2023-08-12 |
rat |
| A J Todd, R C Spike, A R Brodbelt, R F Price, S A Sheha. Some inhibitory neurons in the spinal cord develop c-fos-immunoreactivity after noxious stimulation. Neuroscience. vol 63. issue 3. 1995-04-26. PMID:7898680. |
it is known that some of the cells which produce c-fos in response to noxious stimulation are projection neurons, with axons ascending to the brainstem or thalamus, however, because of the large number of c-fos-immunoreactive cells in the dorsal horn, it is likely that many are interneurons, and some of these are probably excitatory cells which use glutamate as a transmitter. |
1995-04-26 |
2023-08-12 |
rat |
| K A Sluka, H H Jordan, W D Willis, K N Westlun. Differential effects of N-methyl-D-aspartate (NMDA) and non-NMDA receptor antagonists on spinal release of amino acids after development of acute arthritis in rats. Brain research. vol 664. issue 1-2. 1995-04-24. PMID:7895049. |
following induction of acute knee joint arthritis in rats, an increase in the release of amino acids in the spinal dorsal horn occurs in two phases: (1) at the time of injection for all amino acids tested; and (2) a late prolonged phase for aspartate (asp) and glutamate (glu) (3.5-8 h). |
1995-04-24 |
2023-08-12 |
rat |
| J M Castro-Lopes, T R Tölle, B Pan, W Zieglgänsberge. Expression of GAD mRNA in spinal cord neurons of normal and monoarthritic rats. Brain research. Molecular brain research. vol 26. issue 1-2. 1995-03-16. PMID:7854044. |
this study was carried out to investigate whether the increase of gaba levels in spinal cord dorsal horn in response to chronic inflammatory lesions results from an enhanced expression of the gene that governs the production of glutamate decarboxylase (gad), the enzyme responsible for gaba synthesis. |
1995-03-16 |
2023-08-12 |
rat |
| M Ueda, Y Kuraishi, K Sugimoto, M Sato. Evidence that glutamate is released from capsaicin-sensitive primary afferent fibers in rats: study with on-line continuous monitoring of glutamate. Neuroscience research. vol 20. issue 3. 1995-03-02. PMID:7530819. |
in the presence of 0.3 microm tetrodotoxin, 2-min application of capsaicin produced an increased outflow of glutamate, as well as an increase in the release of immunoreactive substance p from dorsal horn slices of the rat. |
1995-03-02 |
2023-08-12 |
rat |
| M Ueda, Y Kuraishi, K Sugimoto, M Sato. Evidence that glutamate is released from capsaicin-sensitive primary afferent fibers in rats: study with on-line continuous monitoring of glutamate. Neuroscience research. vol 20. issue 3. 1995-03-02. PMID:7530819. |
capsaicin at 3 microm failed to increase the release of glutamate from the dorsal horn slices of the rats made an l4-l6 dorsal rhizotomy. |
1995-03-02 |
2023-08-12 |
rat |
| M Ueda, Y Kuraishi, K Sugimoto, M Sato. Evidence that glutamate is released from capsaicin-sensitive primary afferent fibers in rats: study with on-line continuous monitoring of glutamate. Neuroscience research. vol 20. issue 3. 1995-03-02. PMID:7530819. |
these results suggest that capsaicin evoked the release of glutamate from primary afferent fibers in the dorsal horn and that glutamate may play an important role in pain transmission between primary afferent fibers and dorsal horn neurons. |
1995-03-02 |
2023-08-12 |
rat |
| J Broman, F Adah. Evidence for vesicular storage of glutamate in primary afferent terminals. Neuroreport. vol 5. issue 14. 1995-02-22. PMID:7827336. |
the correlation between the density of gold particles signalling fixed glutamate and the density of synaptic vesicles was examined in primary afferent terminals in the rat dorsal horn. |
1995-02-22 |
2023-08-12 |
rat |
| J G Valtschanoff, K D Phend, P S Bernardi, R J Weinberg, A Rustion. Amino acid immunocytochemistry of primary afferent terminals in the rat dorsal horn. The Journal of comparative neurology. vol 346. issue 2. 1994-12-05. PMID:7525664. |
these results support a neurotransmitter role for glutamate in primary afferents to the dorsal horn. |
1994-12-05 |
2023-08-12 |
rat |
| Andrew S C Rice, Stephen B McMaho. Pre-emptive intrathecal administration of an NMDA receptor antagonist (AP-5) prevents hyper-reflexia in a model of persistent visceral pain. Pain. vol 57. issue 3. 1994-11-08. PMID:7936711. |
dorsal horn sensitization following somatic noxious stimuli is partly mediated by the n-methyl-d-aspartate (nmda) sub-type of glutamate receptor. |
1994-11-08 |
2023-08-12 |
rat |
| M R Young, S M Fleetwood-Walker, R Mitchell, F E Munr. Evidence for a role of metabotropic glutamate receptors in sustained nociceptive inputs to rat dorsal horn neurons. Neuropharmacology. vol 33. issue 1. 1994-06-16. PMID:8183438. |
evidence for a role of metabotropic glutamate receptors in sustained nociceptive inputs to rat dorsal horn neurons. |
1994-06-16 |
2023-08-12 |
rat |
| M R Young, S M Fleetwood-Walker, R Mitchell, F E Munr. Evidence for a role of metabotropic glutamate receptors in sustained nociceptive inputs to rat dorsal horn neurons. Neuropharmacology. vol 33. issue 1. 1994-06-16. PMID:8183438. |
several antagonists at metabotropic glutamate (mglu) receptors, when applied ionophoretically, inhibited the excitation of single dorsal horn neurons elicited by cutaneous administration of the c fibre-selective algogen, mustard oil. |
1994-06-16 |
2023-08-12 |
rat |
| K A Sluka, K N Westlun. Behavioral and immunohistochemical changes in an experimental arthritis model in rats. Pain. vol 55. issue 3. 1994-04-05. PMID:7510059. |
an experimental arthritis induced by injection of kaolin and carrageenan into the knee joint resulted in a temporal relationship between glutamate dorsal horn content and paw withdrawal latency (pwl) which was positively correlated. |
1994-04-05 |
2023-08-12 |
rat |
| A J Todd, R C Spike, R F Price, M Neilso. Immunocytochemical evidence that neurotensin is present in glutamatergic neurons in the superficial dorsal horn of the rat. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 14. issue 2. 1994-03-10. PMID:7905517. |
in order to determine whether glutamate is enriched in neurotensin-containing axons in the superficial dorsal horn of the rat spinal cord, we have carried out preembedding immunocytochemistry with an antiserum to neurotensin and then used a postembedding immunogold method with antiserum to glutamate. |
1994-03-10 |
2023-08-12 |
rat |
| A J Todd, R C Spike, R F Price, M Neilso. Immunocytochemical evidence that neurotensin is present in glutamatergic neurons in the superficial dorsal horn of the rat. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 14. issue 2. 1994-03-10. PMID:7905517. |
the level of glutamate immunoreactivity in neurotensin-immunoreactive boutons in dorsal horn was similar to that in cerebellar parallel fiber terminals, but significantly lower than that in mossy fiber terminals. |
1994-03-10 |
2023-08-12 |
rat |
| A J Todd, R C Spike, R F Price, M Neilso. Immunocytochemical evidence that neurotensin is present in glutamatergic neurons in the superficial dorsal horn of the rat. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 14. issue 2. 1994-03-10. PMID:7905517. |
these results suggest that glutamate is a transmitter used by neurotensin-immunoreactive axons in the dorsal horn, and since these axons are thought to be largely or entirely derived from neurotensin-containing neurons in laminae i-iii, they provide immunocytochemical evidence for a population of excitatory glutamatergic neurons in this region. |
1994-03-10 |
2023-08-12 |
rat |
| J Broman, S Anderson, O P Otterse. Enrichment of glutamate-like immunoreactivity in primary afferent terminals throughout the spinal cord dorsal horn. The European journal of neuroscience. vol 5. issue 8. 1994-02-15. PMID:7904222. |
these findings suggest that glutamate, alone or in combination with other neuroactive compounds, is involved in the transfer of all sensory modalities from primary afferent fibres to dorsal horn neurons. |
1994-02-15 |
2023-08-12 |
rat |