| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M J Eaton, J A Plunkett, S Karmally, M A Martinez, K Montane. Changes in GAD- and GABA- immunoreactivity in the spinal dorsal horn after peripheral nerve injury and promotion of recovery by lumbar transplant of immortalized serotonergic precursors. Journal of chemical neuroanatomy. vol 16. issue 1. 1999-04-13. PMID:9924973. |
when endogenous cells of the dorsal horn which contain the neurotransmitter gamma-aminobutyric acid (gaba) and its synthetic enzyme glutamate decarboxylase (gad) were immunohistochemically quantified in the lumbar spinal cord 3 days and 1-8 weeks after cci, the number of gaba- and gad-immunoreactive (ir) cells decreased bilateral to the nerve injury as soon as 3 days after cci. |
1999-04-13 |
2023-08-12 |
rat |
| P Li, A A Calejesan, M Zhu. ATP P2x receptors and sensory synaptic transmission between primary afferent fibers and spinal dorsal horn neurons in rats. Journal of neurophysiology. vol 80. issue 6. 1999-02-10. PMID:9862932. |
glutamate is a major fast transmitter between primary afferent fibers and dorsal horn neurons in the spinal cord. |
1999-02-10 |
2023-08-12 |
rat |
| P Li, A A Calejesan, M Zhu. ATP P2x receptors and sensory synaptic transmission between primary afferent fibers and spinal dorsal horn neurons in rats. Journal of neurophysiology. vol 80. issue 6. 1999-02-10. PMID:9862932. |
no residual current was detected, indicating that glutamate but not atp is a fast transmitter at the dorsal horn of the lumbar spinal cord. |
1999-02-10 |
2023-08-12 |
rat |
| M Sasaki, C Tohda, Y Kuraish. Region-specific increase in glutamate release from dorsal horn of rats with adjuvant inflammation. Neuroreport. vol 9. issue 14. 1999-01-20. PMID:9831454. |
region-specific increase in glutamate release from dorsal horn of rats with adjuvant inflammation. |
1999-01-20 |
2023-08-12 |
rat |
| M Sasaki, C Tohda, Y Kuraish. Region-specific increase in glutamate release from dorsal horn of rats with adjuvant inflammation. Neuroreport. vol 9. issue 14. 1999-01-20. PMID:9831454. |
glutamate is considered an important pain transmitter and responsible for inflammatory hyperalgesia, but quantitative and topographical changes in glutamate release in the dorsal horn during peripheral inflammation have not been characterized. |
1999-01-20 |
2023-08-12 |
rat |
| F We. [Chemical anatomy of the nociceptive transmission and modulation in the spinal dorsal horn]. Sheng li ke xue jin zhan [Progress in physiology]. vol 27. issue 4. 1998-11-06. PMID:9772383. |
these results provide evidence that acute pain evolved co-release of substance p and glutamate from c-fiber terminals may constitute a driving force for secondary activation of ascending projection neurons or of internal gabaergic antinoceciptive system directly via their receptors in the dorsal horn of the spinal cord. |
1998-11-06 |
2023-08-12 |
Not clear |
| R C Kerr, D J Maxwell, A J Tod. GluR1 and GluR2/3 subunits of the AMPA-type glutamate receptor are associated with particular types of neurone in laminae I-III of the spinal dorsal horn of the rat. The European journal of neuroscience. vol 10. issue 1. 1998-10-08. PMID:9753141. |
glur1 and glur2/3 subunits of the ampa-type glutamate receptor are associated with particular types of neurone in laminae i-iii of the spinal dorsal horn of the rat. |
1998-10-08 |
2023-08-12 |
rat |
| T Sasamura, M Sasaki, C Tohda, Y Kuraish. Existence of capsaicin-sensitive glutamatergic terminals in rat hypothalamus. Neuroreport. vol 9. issue 9. 1998-09-25. PMID:9674591. |
capsaicin evoked glutamate release from slices of hypothalamus and lumbar dorsal horn, but not cerebellum. |
1998-09-25 |
2023-08-12 |
rat |
| L C Stanfa, A H Dickenso. Inflammation alters the effects of mGlu receptor agonists on spinal nociceptive neurones. European journal of pharmacology. vol 347. issue 2-3. 1998-09-17. PMID:9653877. |
this study examined the effects of the metabotropic glutamate receptor agonists (1s,3r)-1-aminocyclopentane-1,3-dicarboxylic acid ((1s,3r)-acpd), (s)-3,5-dihydroxyphenylglycine ((s)-3,5-dhpg) and (1s,3s)-1-aminocyclopentane-1,3-dicarboxylic acid ((1s,3s)-acpd) on the electrically evoked responses of dorsal horn neurones recorded in normal animals and in animals 3 h after the induction of carrageenan inflammation. |
1998-09-17 |
2023-08-12 |
Not clear |
| S Sequeira, J Näsströ. Low-affinity kainate receptors and long-lasting depression of NMDA-receptor-mediated currents in rat superficial dorsal horn. Journal of neurophysiology. vol 80. issue 2. 1998-09-04. PMID:9705476. |
in an in vitro spinal cord slice preparation whole cell electrophysiological recordings of rat superficial dorsal horn neurons responding differentially to glutamate (glu) and n-methyl-d-aspartate (nmda) were investigated systematically for the role of kainate (ka) receptors in modulating their activity. |
1998-09-04 |
2023-08-12 |
rat |
| K K Yun. Localization of glutamate receptors in dorsal horn of rat spinal cord. Neuroreport. vol 9. issue 7. 1998-08-24. PMID:9631479. |
localization of glutamate receptors in dorsal horn of rat spinal cord. |
1998-08-24 |
2023-08-12 |
rat |
| K K Yun. Localization of glutamate receptors in dorsal horn of rat spinal cord. Neuroreport. vol 9. issue 7. 1998-08-24. PMID:9631479. |
immunocytochemical localization of metabotropic glutamate receptors (mglurs) and ionotropic glutamate receptors (nmda-type: nmdar1 and nmdar2a-c; ampa-type: glur1-4) was performed on sections of rat dorsal horn. |
1998-08-24 |
2023-08-12 |
rat |
| K K Yun. Localization of glutamate receptors in dorsal horn of rat spinal cord. Neuroreport. vol 9. issue 7. 1998-08-24. PMID:9631479. |
in addition, immunoreactivity for receptors was found to co-localize with immunoreactivity for glutamate in the dorsal horn. |
1998-08-24 |
2023-08-12 |
rat |
| K K Yun. Localization of glutamate receptors in dorsal horn of rat spinal cord. Neuroreport. vol 9. issue 7. 1998-08-24. PMID:9631479. |
the present results indicate that glutamate receptors are differentially localized in neuronal elements of dorsal horn where receptor-neurotransmitter interaction takes place. |
1998-08-24 |
2023-08-12 |
rat |
| S L Jone. Noxious heat-evoked fos-like immunoreactivity in the rat lumbar dorsal horn is inhibited by glutamate microinjections in the upper cervical spinal cord. Brain research. vol 788. issue 1-2. 1998-07-23. PMID:9555087. |
noxious heat-evoked fos-like immunoreactivity in the rat lumbar dorsal horn is inhibited by glutamate microinjections in the upper cervical spinal cord. |
1998-07-23 |
2023-08-12 |
rat |
| P K Zahn, E Umali, T J Brenna. Intrathecal non-NMDA excitatory amino acid receptor antagonists inhibit pain behaviors in a rat model of postoperative pain. Pain. vol 74. issue 2-3. 1998-05-04. PMID:9520236. |
evidence indicates that excitatory amino acids (eaas) like glutamate and aspartate are important in the processing of nociceptive information in the dorsal horn of the spinal cord. |
1998-05-04 |
2023-08-12 |
rat |
| S M Carlton, G L Hargett, R E Coggeshal. Plasticity in alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor subunits in the rat dorsal horn following deafferentation. Neuroscience letters. vol 242. issue 1. 1998-04-28. PMID:9509995. |
glutamate activation of these receptors could initiate or potentiate second messenger cascades that could well contribute to neuronal changes documented in the dorsal horn of deafferented animals. |
1998-04-28 |
2023-08-12 |
rat |
| J R Naranjo, B Mellström, A M Carrión, J J Lucas, N S Foulkes, P Sassone-Cors. Peripheral noxious stimulation induces CREM expression in dorsal horn: involvement of glutamate. The European journal of neuroscience. vol 9. issue 12. 1998-04-24. PMID:9517483. |
peripheral noxious stimulation induces crem expression in dorsal horn: involvement of glutamate. |
1998-04-24 |
2023-08-12 |
Not clear |
| Y Q Cao, P W Mantyh, E J Carlson, A M Gillespie, C J Epstein, A I Basbau. Primary afferent tachykinins are required to experience moderate to intense pain. Nature. vol 392. issue 6674. 1998-04-16. PMID:9537322. |
because blockers of glutamate receptors reliably reduce pain behaviour, it is assumed that 'pain' messages are mediated by glutamate action on dorsal horn neurons. |
1998-04-16 |
2023-08-12 |
mouse |
| K Okano, M Ueda, Y Kuraishi, M Sato. Effect of repeated cold stress on capsaicin-evoked release of glutamate from rat spinal dorsal horn slices. Neuroscience research. vol 29. issue 4. 1998-04-02. PMID:9527623. |
effect of repeated cold stress on capsaicin-evoked release of glutamate from rat spinal dorsal horn slices. |
1998-04-02 |
2023-08-12 |
rat |