| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| David L Somers, F Richard Clement. Dorsal horn synaptosomal content of aspartate, glutamate, glycine and GABA are differentially altered following chronic constriction injury to the rat sciatic nerve. Neuroscience letters. vol 323. issue 3. 2002-06-25. PMID:11959412. |
dorsal horn, synaptosomal content of aspartate (asp), glutamate (glu), glycine and gamma-aminobutyric acid (gaba) was assessed in these rats, and in normal age-matched and younger rats. |
2002-06-25 |
2023-08-12 |
rat |
| Deolinda Lima, Armando Almeid. The medullary dorsal reticular nucleus as a pronociceptive centre of the pain control system. Progress in neurobiology. vol 66. issue 2. 2002-06-18. PMID:11900883. |
drt blocking by lidocaine results in a decrease of the nociceptive activity of spinal dorsal horn neurones, whereas stimulation by glutamate has the opposite effect. |
2002-06-18 |
2023-08-12 |
Not clear |
| Seiji Ohtori, Kazuhisa Takahashi, Hidetoshi Ino, Tanemichi Chiba, Masatsune Yamagata, Hiroaki Sameda, Hideshige Moriy. Up-regulation of substance P and NMDA receptor mRNA in dorsal horn and preganglionic sympathetic neurons during adjuvant-induced noxious stimulation in rats. Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft. vol 184. issue 1. 2002-04-09. PMID:11876485. |
sp receptor (spr) and n-methyl-d-aspartate type glutamate receptor (nmdar) were also recognized in portions of the dorsal horn and psns. |
2002-04-09 |
2023-08-12 |
rat |
| Seiji Ohtori, Kazuhisa Takahashi, Hidetoshi Ino, Tanemichi Chiba, Masatsune Yamagata, Hiroaki Sameda, Hideshige Moriy. Up-regulation of substance P and NMDA receptor mRNA in dorsal horn and preganglionic sympathetic neurons during adjuvant-induced noxious stimulation in rats. Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft. vol 184. issue 1. 2002-04-09. PMID:11876485. |
primary sensory nerve fibers containing sp and glutamate terminated around psns, or partly on psns directly as well as on dorsal horn neurons (dhns). |
2002-04-09 |
2023-08-12 |
rat |
| A U Asghar, G C Bird, A E Kin. Glutamate uptake inhibition modulates dorsal horn neurotransmission: a comparison between normal and arthritic rats. Neuroreport. vol 12. issue 18. 2002-03-18. PMID:11742238. |
glutamate uptake inhibition modulates dorsal horn neurotransmission: a comparison between normal and arthritic rats. |
2002-03-18 |
2023-08-12 |
rat |
| A U Asghar, G C Bird, A E Kin. Glutamate uptake inhibition modulates dorsal horn neurotransmission: a comparison between normal and arthritic rats. Neuroreport. vol 12. issue 18. 2002-03-18. PMID:11742238. |
this study determined the effects of glutamate uptake inhibition on primary-afferent excitatory postsynaptic potentials (dr-epsps) in spinal dorsal horn neurones in vitro from naive rats and rats with localised arthritis. |
2002-03-18 |
2023-08-12 |
rat |
| S Mens. [Pathophysiology of low back pain and the transition to the chronic state - experimental data and new concepts]. Schmerz (Berlin, Germany). vol 15. issue 6. 2002-02-22. PMID:11793144. |
one reason for the myositis-induced expansion of the input region is hyperexcitability of the neurones caused by the release of sp and glutamate from the spinal terminals of muscle afferents with ensuing activation of nmda channels in dorsal horn neurones (central sensitisation). |
2002-02-22 |
2023-08-12 |
rat |
| S Mens. [Pathophysiology of low back pain and the transition to the chronic state - experimental data and new concepts]. Schmerz (Berlin, Germany). vol 15. issue 6. 2002-02-22. PMID:11793144. |
in contrast to excitability, the resting activity of dorsal horn neurones - which is likely to induce spontaneous pain in patients - does not appear to depend on the release of sp and glutamate but on the concentration of nitric oxide (no) in the spinal cord. |
2002-02-22 |
2023-08-12 |
rat |
| J Y Hu, Z Q Zha. Differential contributions of NMDA and non-NMDA receptors to spinal Fos expression evoked by superficial tissue and muscle inflammation in the rat. Neuroscience. vol 106. issue 4. 2002-01-04. PMID:11682167. |
these results indicate that different glutamate receptors in the dorsal horn of the spinal cord may mediate nociceptive input from superficial tissue (particularly skin) and muscle. |
2002-01-04 |
2023-08-12 |
rat |
| A B MacDermot. Glutamate and GABA: a painful combination. Neuron. vol 32. issue 3. 2001-12-20. PMID:11709147. |
report that neurotransmitter release from inhibitory dorsal horn neurons is affected by activation of presynaptic kainate-type glutamate receptors. |
2001-12-20 |
2023-08-12 |
Not clear |
| Kiran Yashpal, Kim Fisher, Jean-Guy Chabot, Terence J Coderr. Differential effects of NMDA and group I mGluR antagonists on both nociception and spinal cord protein kinase C translocation in the formalin test and a model of neuropathic pain in rats. Pain. vol 94. issue 1. 2001-12-07. PMID:11576741. |
noxious stimulus-induced pkc translocation likely depends on glutamate activity at either n-methyl-d-aspartate (nmda) receptors or group i metabotropic glutamate receptors (mglur1/5) in the spinal cord dorsal horn. |
2001-12-07 |
2023-08-12 |
rat |
| G C Bird, A U Asghar, M A Ackley, A E Kin. Modulation of primary afferent-mediated neurotransmission and Fos expression by glutamate uptake inhibition in rat spinal neurones in vitro. Neuropharmacology. vol 41. issue 5. 2001-12-07. PMID:11587713. |
the effect of altered endogenous levels of synaptic glutamate on neurotransmission and synaptic dorsal horn fos expression was determined in rat spinal cord in vitro. |
2001-12-07 |
2023-08-12 |
rat |
| X J Song, Y S Shu, P B Yin, Z Q Zha. Detection of release of aspartate and glutamate in cat spinal dorsal horn following noxious stimulation of cutaneous and muscular afferent fibers using microdialysis. Sheng li xue bao : [Acta physiologica Sinica]. vol 51. issue 3. 2001-10-18. PMID:11499000. |
detection of release of aspartate and glutamate in cat spinal dorsal horn following noxious stimulation of cutaneous and muscular afferent fibers using microdialysis. |
2001-10-18 |
2023-08-12 |
cat |
| X J Song, Y S Shu, P B Yin, Z Q Zha. Detection of release of aspartate and glutamate in cat spinal dorsal horn following noxious stimulation of cutaneous and muscular afferent fibers using microdialysis. Sheng li xue bao : [Acta physiologica Sinica]. vol 51. issue 3. 2001-10-18. PMID:11499000. |
to investigate the possible mechanisms underlying the difference of nmda and non-nmda receptors in spinal nociception originating in skin and muscle, release of aspartate (asp) and glutamate (glu) in the spinal dorsal horn was detected by stimulation of cutaneous and muscular nerves in cats using microdialysis technique. |
2001-10-18 |
2023-08-12 |
cat |
| T Nakatsuka, J G G. ATP P2X receptor-mediated enhancement of glutamate release and evoked EPSCs in dorsal horn neurons of the rat spinal cord. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 17. 2001-09-20. PMID:11517241. |
atp p2x receptor-mediated enhancement of glutamate release and evoked epscs in dorsal horn neurons of the rat spinal cord. |
2001-09-20 |
2023-08-12 |
rat |
| S Takum. Effect of neonatal capsaicin treatment on neural activity in the medullary dorsal horn of neonatal rats evoked by electrical stimulation to the trigeminal afferents: an optical, electrophysiological, and quantitative study. Brain research. vol 906. issue 1-2. 2001-09-13. PMID:11430856. |
to elucidate which glutamate receptors, nmda or non-nmda, have the main role in synaptic transmission via unmyelinated afferents in the trigeminal subnucleus caudalis (the medullary dorsal horn), and to examine the early functional effects of neonatal capsaicin treatment to the subnucleus caudalis, optical recording, field potential recording, and quantitative study using electron micrographs were employed. |
2001-09-13 |
2023-08-12 |
rat |
| V Morisset, L Urba. Cannabinoid-induced presynaptic inhibition of glutamatergic EPSCs in substantia gelatinosa neurons of the rat spinal cord. Journal of neurophysiology. vol 86. issue 1. 2001-08-30. PMID:11431486. |
in conclusion, these results strongly suggest a presynaptic location for cb(1) receptors whose activation results in inhibition of glutamate release in the spinal dorsal horn. |
2001-08-30 |
2023-08-12 |
rat |
| S J Hwang, S Pagliardini, A Rustioni, J G Valtschanof. Presynaptic kainate receptors in primary afferents to the superficial laminae of the rat spinal cord. The Journal of comparative neurology. vol 436. issue 3. 2001-08-30. PMID:11438930. |
subunits of glutamate receptors participate in the regulation of sensory transmission at primary afferent synapses in the superficial laminae of dorsal horn (dh). |
2001-08-30 |
2023-08-12 |
rat |
| R E Coggeshall, H A Lekan, F A White, C J Wool. A-fiber sensory input induces neuronal cell death in the dorsal horn of the adult rat spinal cord. The Journal of comparative neurology. vol 435. issue 3. 2001-08-09. PMID:11406811. |
in this study, we asked whether activity in myelinated afferents (a fibers), which use glutamate as a transmitter, can induce cell death in the dorsal horn. |
2001-08-09 |
2023-08-12 |
rat |
| P Li, M Zhu. Cholinergic, noradrenergic, and serotonergic inhibition of fast synaptic transmission in spinal lumbar dorsal horn of rat. Brain research bulletin. vol 54. issue 6. 2001-07-26. PMID:11403990. |
glutamate is the major fast excitatory transmitter between primary afferent fibers and spinal dorsal horn neurons. |
2001-07-26 |
2023-08-12 |
rat |