All Relations between glutamate and spinal cord posterior horn

Publication Sentence Publish Date Extraction Date Species
K Okano, M Ueda, Y Kuraishi, M Sato. Effect of repeated cold stress on capsaicin-evoked release of glutamate from rat spinal dorsal horn slices. Neuroscience research. vol 29. issue 4. 1998-04-02. PMID:9527623. in the presence of 0.3 microm tetrodotoxin, the application of 1 microm capsaicin to spinal dorsal horn slices evoked glutamate release (18.6 +/- 1.2 pmol mg(-1) protein, n = 11). 1998-04-02 2023-08-12 rat
K Okano, M Ueda, Y Kuraishi, M Sato. Effect of repeated cold stress on capsaicin-evoked release of glutamate from rat spinal dorsal horn slices. Neuroscience research. vol 29. issue 4. 1998-04-02. PMID:9527623. the present results suggest that the facilitated release of glutamate from capsaicin-sensitive primary afferent terminals in the spinal dorsal horn is, at least in part, involved in the hyperalgesia of rcs rats as well as the complete freund's adjuvant-induced hyperalgesia. 1998-04-02 2023-08-12 rat
D Budai, A A Larso. The involvement of metabotropic glutamate receptors in sensory transmission in dorsal horn of the rat spinal cord. Neuroscience. vol 83. issue 2. 1998-03-12. PMID:9460763. the involvement of metabotropic glutamate receptors in sensory transmission in dorsal horn of the rat spinal cord. 1998-03-12 2023-08-12 rat
D Budai, A A Larso. The involvement of metabotropic glutamate receptors in sensory transmission in dorsal horn of the rat spinal cord. Neuroscience. vol 83. issue 2. 1998-03-12. PMID:9460763. the role of metabotropic glutamate receptors in the processing of somatosensory information was studied in dorsal horn neurons of the rat spinal cord. 1998-03-12 2023-08-12 rat
D Budai, A A Larso. The involvement of metabotropic glutamate receptors in sensory transmission in dorsal horn of the rat spinal cord. Neuroscience. vol 83. issue 2. 1998-03-12. PMID:9460763. activation of metabotropic glutamate receptors by local iontophoresis of (1s,3r)-1-amino-cyclopentane-1,3-dicarboxylic acid resulted in an increased response of dorsal horn neurons to ionotropic glutamate receptor agonists (n-methyl-d-aspartate and kainic acid) applied by iontophoresis. 1998-03-12 2023-08-12 rat
D Budai, A A Larso. The involvement of metabotropic glutamate receptors in sensory transmission in dorsal horn of the rat spinal cord. Neuroscience. vol 83. issue 2. 1998-03-12. PMID:9460763. the results suggest an interaction between metabotropic and ionotropic glutamate receptors in spinal dorsal horn neurons. 1998-03-12 2023-08-12 rat
J G Cui, W T O'Connor, U Ungerstedt, B Linderoth, B A Meyerso. Spinal cord stimulation attenuates augmented dorsal horn release of excitatory amino acids in mononeuropathy via a GABAergic mechanism. Pain. vol 73. issue 1. 1998-01-30. PMID:9414060. in the present study, using microdialysis, it is shown that scs induces a decreased release of the dorsal horn excitatory amino acids (eaa), glutamate and aspartate, concomitant with an increase of the gaba release. 1998-01-30 2023-08-12 rat
J C Marvizón, V Martínez, E F Grady, N W Bunnett, E A Maye. Neurokinin 1 receptor internalization in spinal cord slices induced by dorsal root stimulation is mediated by NMDA receptors. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 17. issue 21. 1997-11-20. PMID:9334388. glutamate is an excitatory neurotransmitter in the dorsal horn, and its effects are enhanced by sp acting on neurokinin 1 receptors (nk1rs). 1997-11-20 2023-08-12 Not clear
J G Gu, A B MacDermot. Activation of ATP P2X receptors elicits glutamate release from sensory neuron synapses. Nature. vol 389. issue 6652. 1997-11-03. PMID:9338789. these action potentials propagate to drg central terminals in the dorsal horn of the spinal cord, evoking release of excitatory transmitters such as glutamate onto postsynaptic dorsal horn neurons. 1997-11-03 2023-08-12 Not clear
Mikito Kawamata, Keiichi Omot. Involvement of increased excitatory amino acids and intracellular Ca2+ concentration in the spinal dorsal horn in an animal model of neuropathic pain. Pain. vol 68. issue 1. 1997-09-26. PMID:9252003. in cci rats, significant increases were observed in glutamate and aspartate contents on the ipsilateral side of the dorsal horn to nerve ligation on days 4, 7 and 14 (p < 0.001). 1997-09-26 2023-08-12 rat
Mikito Kawamata, Keiichi Omot. Involvement of increased excitatory amino acids and intracellular Ca2+ concentration in the spinal dorsal horn in an animal model of neuropathic pain. Pain. vol 68. issue 1. 1997-09-26. PMID:9252003. we interpret these results to indicate that neuropathic hyperalgesia induced by cci in the rat is associated with an increase in glutamate and aspartate contents and the subsequent activation of nmda receptors, followed by an increase in [ca2+]i within dorsal horn of the spinal cord. 1997-09-26 2023-08-12 rat
Ulrich Hoheisel, Birgitta Sander, Siegfried Mens. Myositis-induced functional reorganisation of the rat dorsal horn: effects of spinal superfusion with antagonists to neurokinin and glutamate receptors. Pain. vol 69. issue 3. 1997-06-19. PMID:9085295. myositis-induced functional reorganisation of the rat dorsal horn: effects of spinal superfusion with antagonists to neurokinin and glutamate receptors. 1997-06-19 2023-08-12 rat
H Li, H Ohishi, A Kinoshita, R Shigemoto, S Nomura, N Mizun. Localization of a metabotropic glutamate receptor, mGluR7, in axon terminals of presumed nociceptive, primary afferent fibers in the superficial layers of the spinal dorsal horn: an electron microscope study in the rat. Neuroscience letters. vol 223. issue 3. 1997-06-04. PMID:9080455. localization of a metabotropic glutamate receptor, mglur7, in axon terminals of presumed nociceptive, primary afferent fibers in the superficial layers of the spinal dorsal horn: an electron microscope study in the rat. 1997-06-04 2023-08-12 rat
H Li, H Ohishi, A Kinoshita, R Shigemoto, S Nomura, N Mizun. Localization of a metabotropic glutamate receptor, mGluR7, in axon terminals of presumed nociceptive, primary afferent fibers in the superficial layers of the spinal dorsal horn: an electron microscope study in the rat. Neuroscience letters. vol 223. issue 3. 1997-06-04. PMID:9080455. it was examined electron microscopically in the rat if a metabotropic glutamate receptor, mglur7, might be localized in axon terminals of nociceptive, primary afferent fibers in laminae i and ii of the spinal dorsal horn. 1997-06-04 2023-08-12 rat
R E Russo, F Nagy, J Hounsgaar. Modulation of plateau properties in dorsal horn neurones in a slice preparation of the turtle spinal cord. The Journal of physiology. vol 499 ( Pt 2). 1997-05-30. PMID:9080374. we propose that modulation of postsynaptic plateau properties in dorsal horn neurones by activation of type i metabotropic glutamate receptors and nk-1 tachykinin receptors is involved in processing nociceptive information. 1997-05-30 2023-08-12 Not clear
Z Ye, K N Westlun. Ultrastructural localization of glutamate receptor subunits (NMDAR1, AMPA GluR1 and GluR2/3) and spinothalamic tract cells. Neuroreport. vol 7. issue 15-17. 1997-04-01. PMID:8981427. the associations of glutamate receptor subunits (nmdar1, ampa glur1 and glur2/3) and spinothalamic tract neurons in the rat lumbar spinal cord dorsal horn were investigated. 1997-04-01 2023-08-12 rat
M Tomiyama, R Rodriguez-Puertas, R Cortés, A Christnacher, B Sommer, A Pazos, J M Palacios, G Mengo. Differential regional distribution of AMPA receptor subunit messenger RNAs in the human spinal cord as visualized by in situ hybridization. Neuroscience. vol 75. issue 3. 1997-03-19. PMID:8951883. this differential distribution of transcripts in the dorsal horn suggests that the subunit composition of ampa receptors varies with the afferent inputs; ampa receptors on neurons in the superficial dorsal horn, where terminals of thin primary afferents conducting noxious information are located, contain more flip forms, whereas neurons in the deep dorsal horn, where thick primary afferents mediating innocuous stimuli terminate, have ampa receptors which are mainly composed of flop forms of glutamate receptor subunits a and b. 1997-03-19 2023-08-12 human
M Tomiyama, R Rodriguez-Puertas, R Cortés, A Christnacher, B Sommer, A Pazos, J M Palacios, G Mengo. Differential regional distribution of AMPA receptor subunit messenger RNAs in the human spinal cord as visualized by in situ hybridization. Neuroscience. vol 75. issue 3. 1997-03-19. PMID:8951883. the relatively high abundance of glutamate receptor subunit b transcripts in the superficial laminae of the dorsal horn indicates that ampa receptors in these laminae have lower ca2+ permeability. 1997-03-19 2023-08-12 human
M Tomiyama, R Rodriguez-Puertas, R Cortés, A Christnacher, B Sommer, A Pazos, J M Palacios, G Mengo. Differential regional distribution of AMPA receptor subunit messenger RNAs in the human spinal cord as visualized by in situ hybridization. Neuroscience. vol 75. issue 3. 1997-03-19. PMID:8951883. in addition, the relative abundance of glutamate receptor subunits bflip and dflop may show that ampa receptors in the superficial dorsal horn have slow desensitization, while those of motor neurons have rapid desensitization. 1997-03-19 2023-08-12 human
L Maxwell, D J Maxwell, M Neilson, R Ker. A confocal microscopic survey of serotoninergic axons in the lumbar spinal cord of the rat: co-localization with glutamate decarboxylase and neuropeptides. Neuroscience. vol 75. issue 2. 1997-03-14. PMID:8931011. those containing glutamate decarboxylase terminate in the superficial dorsal horn and are likely to be involved in antinociception, whereas those containing peptides terminate principally in motor nuclei and are likely to modulate motor activity. 1997-03-14 2023-08-12 rat