| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Shuai Liu, Wenhui Qiu, Rongzhen Li, Bei Chen, Xin Wu, Jason T Magnuson, Bentuo Xu, Shusheng Luo, Elvis Genbo Xu, Chunmiao Zhen. Perfluorononanoic Acid Induces Neurotoxicity via Synaptogenesis Signaling in Zebrafish. Environmental science & technology. 2023-02-16. PMID:36797597. |
neurotransmitter levels (acetylcholine, glutamate, 5-hydroxytryptamine, γ-aminobutyric acid, dopamine, and noradrenaline) were significantly decreased in zebrafish larvae, and the tg( |
2023-02-16 |
2023-08-14 |
zebrafish |
| Ewa Lepiarczyk, Łukasz Paukszto, Marta Wiszpolska, Elżbieta Łopieńska-Biernat, Agnieszka Bossowska, Mariusz Krzysztof Majewski, Marta Majewsk. Molecular Influence of Resiniferatoxin on the Urinary Bladder Wall Based on Differential Gene Expression Profiling. Cells. vol 12. issue 3. 2023-02-11. PMID:36766804. |
interestingly, rtx intravesical installation was followed by changes in the expression of genes involved in synaptic plasticity and neuromodulation, including 5-ht, h2s, glutamate, and gaba transmission. |
2023-02-11 |
2023-08-14 |
Not clear |
| Camille de Almeida, Nida Chabbah, Camille Eyraud, Caroline Fasano, Véronique Bernard, Nicolas Pietrancosta, Véronique Fabre, Salah El Mestikawy, Stephanie Dauma. Absence of VGLUT3 expression leads to impaired fear memory in mice. eNeuro. 2023-01-31. PMID:36720646. |
the atypical subtype, vglut3 is responsible for the co-transmission of glutamate with acetylcholine (ach), serotonin (5-ht) or gaba.to understand the involvement of vglut3-dependent cotransmission in aversive memories, we used a pavlovian fear conditioning paradigm in vglut3 |
2023-01-31 |
2023-08-14 |
mouse |
| Heng-Chang Zhang, Yang Du, Lei Chen, Zeng-Qiang Yuan, Yong Chen. MicroRNA Schizophrenia: Etiology, Biomarkers and Therapeutic Targets. Neuroscience and biobehavioral reviews. 2023-01-27. PMID:36707012. |
it is now commonly believed that in addition to the traditional dopaminergic mesolimbic pathway, the etiology of schizophrenia also includes neuronal networks, such as glutamate, gaba, serotonin, bdnf, oxidative stress, inflammation and the immune system. |
2023-01-27 |
2023-08-14 |
human |
| Jonaid Ahmad Malik, Zahid Yaseen, Lahari Thotapalli, Sakeel Ahmed, Mohd Farooq Shaikh, Sirajudheen Anwa. Understanding translational research in schizophrenia: A novel insight into animal models. Molecular biology reports. 2023-01-24. PMID:36692676. |
dopamine, glutamate, gaba, and serotonin are the neurotransmitters involved in the pathophysiology of schizophrenia. |
2023-01-24 |
2023-08-14 |
Not clear |
| Jonaid Ahmad Malik, Zahid Yaseen, Lahari Thotapalli, Sakeel Ahmed, Mohd Farooq Shaikh, Sirajudheen Anwa. Understanding translational research in schizophrenia: A novel insight into animal models. Molecular biology reports. 2023-01-24. PMID:36692676. |
hypothesis based on dopamine, glutamate, and serotonin are considered successful models of schizophrenia on which drug therapies have been designed to date. |
2023-01-24 |
2023-08-14 |
Not clear |
| Yifeng Shi, Mengqi Wang, Linglong Xiao, Luolan Gui, Wen Zheng, Lin Bai, Bo Su, Bin Li, Yangyang Xu, Wei Pan, Jie Zhang, Wei Wan. Potential therapeutic mechanism of deep brain stimulation of the nucleus accumbens in obsessive-compulsive disorder. Frontiers in cellular neuroscience. vol 16. 2023-01-23. PMID:36687525. |
furthermore, we found that the local levels of monoamines [dopamine (da) and serotonin (5-ht)] and amino acids [glutamate (glu) and gamma-aminobutyric acid (gaba)] in the nac were increased in ocd status, and that the expression of the two types of da receptors in the nac exhibited an opposite change. |
2023-01-23 |
2023-08-14 |
rat |
| Stefania Dimonte, Vladyslav Sikora, Maria Bove, Maria Grazia Morgese, Paolo Tucci, Stefania Schiavone, Luigia Trabac. Social isolation from early life induces anxiety-like behaviors in adult rats: Relation to neuroendocrine and neurochemical dysfunctions. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 158. 2023-01-02. PMID:36592494. |
social isolation also caused a reduction of noradrenaline, serotonin and gaba levels, together with an increase of serotonin turnover and glutamate levels in the amygdala of isolated animals. |
2023-01-02 |
2023-08-14 |
human |
| Stefania Dimonte, Vladyslav Sikora, Maria Bove, Maria Grazia Morgese, Paolo Tucci, Stefania Schiavone, Luigia Trabac. Social isolation from early life induces anxiety-like behaviors in adult rats: Relation to neuroendocrine and neurochemical dysfunctions. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 158. 2023-01-02. PMID:36592494. |
no significant differences were found in noradrenaline and serotonin levels, as well as in serotonin turnover in hippocampus, while glutamate amount was increased and gaba levels were reduced in isolated rats. |
2023-01-02 |
2023-08-14 |
human |
| Djawad Radjabzadeh, Jos A Bosch, André G Uitterlinden, Aeilko H Zwinderman, M Arfan Ikram, Joyce B J van Meurs, Annemarie I Luik, Max Nieuwdorp, Anja Lok, Cornelia M van Duijn, Robert Kraaij, Najaf Ami. Gut microbiome-wide association study of depressive symptoms. Nature communications. vol 13. issue 1. 2022-12-06. PMID:36473852. |
these bacteria are known to be involved in the synthesis of glutamate, butyrate, serotonin and gamma amino butyric acid (gaba), which are key neurotransmitters for depression. |
2022-12-06 |
2023-08-14 |
human |
| Carla V Argañaraz, Tamara S Adjimann, Paula P Perissinotti, Mariano Soiza-Reill. Selective refinement of glutamate and GABA synapses on dorsal raphe 5-HT neurons during postnatal life. Development (Cambridge, England). 2022-12-02. PMID:36458556. |
selective refinement of glutamate and gaba synapses on dorsal raphe 5-ht neurons during postnatal life. |
2022-12-02 |
2023-08-14 |
mouse |
| Carla V Argañaraz, Tamara S Adjimann, Paula P Perissinotti, Mariano Soiza-Reill. Selective refinement of glutamate and GABA synapses on dorsal raphe 5-HT neurons during postnatal life. Development (Cambridge, England). 2022-12-02. PMID:36458556. |
we investigated in mice the postnatal trajectory of glutamate and gaba synaptic inputs to dorsal raphe nucleus (drn) 5-ht neurons, the main source of forebrain 5-ht. |
2022-12-02 |
2023-08-14 |
mouse |
| Niklas Reich, Christian Hölsche. Beyond Appetite: Acylated Ghrelin As A Learning, Memory and Fear Behavior-modulating Hormone. Neuroscience and biobehavioral reviews. 2022-11-11. PMID:36368526. |
as such, in this review, we i) evaluate what specific stages and forms of memory, as well as which respective brain areas are affected by acylated ghrelin, ii) illustrate the plasticity-associated signaling pathways of ag in the hippocampus, also involving memory resolution-enhancing neurogenesis, iii) elucidate how the peptide modulates neurotransmitter systems (glutamate, γ-aminobutyric acid, dopamine, serotonin), iv) clarify the role of ag in conditioned taste aversion, novelty learning and the formation of spatial, recognition, auditory fear, contextual fear and passive avoidance memories in the hippocampus and amygdala as well as v) solve the mystery behind ag, its impact on the 5-ht system, the recently established link to post-traumatic stress disorder and the either fear-suppressing or fear-potentiating effects under neutral and acutely stressed conditions or chronic stress, respectively. |
2022-11-11 |
2023-08-14 |
Not clear |
| Rachel Little, Dale D'Mell. A Cannabinoid Hypothesis of Schizophrenia: Pathways to Psychosis. Innovations in clinical neuroscience. vol 19. issue 7-9. 2022-10-07. PMID:36204167. |
observations regarding psychostimulant and psychedelic drug-induced psychotic states led to the dopamine, serotonin, and glutamate hypotheses of schizophrenia. |
2022-10-07 |
2023-08-14 |
Not clear |
| Ruizhuo Li, Mengjuan Deng, Yuhong Lin, Wenjing Gao, Bohao Liu, Huimin Xi. Genetically predicted circulating levels of glycine, glutamate, and serotonin in relation to the risks of three major neurodegenerative diseases: A Mendelian randomization analysis. Frontiers in aging neuroscience. vol 14. 2022-09-26. PMID:36158554. |
genetically predicted circulating levels of glycine, glutamate, and serotonin in relation to the risks of three major neurodegenerative diseases: a mendelian randomization analysis. |
2022-09-26 |
2023-08-14 |
Not clear |
| Ruizhuo Li, Mengjuan Deng, Yuhong Lin, Wenjing Gao, Bohao Liu, Huimin Xi. Genetically predicted circulating levels of glycine, glutamate, and serotonin in relation to the risks of three major neurodegenerative diseases: A Mendelian randomization analysis. Frontiers in aging neuroscience. vol 14. 2022-09-26. PMID:36158554. |
here, a mendelian randomization (mr) study was conducted to explore whether genetically predicted concentrations of glycine, glutamate and serotonin were associated with risks of alzheimer's disease (ad), parkinson's disease (pd), and amyotrophic lateral sclerosis (als). |
2022-09-26 |
2023-08-14 |
Not clear |
| V N Zorina, A Ya Bespalov, K A Krasnov, A S Melekhova, V L Reinu. [Prospects for the development of new prolonged forms of valproic acid derivatives for the relief of convulsive syndrome]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. vol 122. issue 7. 2022-07-29. PMID:35904287. |
the antiepileptic, mood stabilizing and neuroprotective properties of valproate due to pre- and postsynaptic modulation of gaba-ergic transmission, regulation of glutamate activity, serotonin and dopamine levels in the hippocampus, modulation of sodium, calcium and potassium channels, epigenetic effects on the body are described. |
2022-07-29 |
2023-08-14 |
Not clear |
| Adam Wojtas, Agnieszka Bysiek, Agnieszka Wawrzczak-Bargiela, Zuzanna Szych, Iwona Majcher-Maślanka, Monika Herian, Marzena Maćkowiak, Krystyna Gołembiowsk. Effect of Psilocybin and Ketamine on Brain Neurotransmitters, Glutamate Receptors, DNA and Rat Behavior. International journal of molecular sciences. vol 23. issue 12. 2022-06-24. PMID:35743159. |
ketamine (10 mg/kg) and psilocybin (2 and 10 mg/kg) increased dopamine, serotonin, glutamate and gaba extracellular levels in the frontal cortex, while psilocybin also increased gaba in the reticular nucleus of the thalamus. |
2022-06-24 |
2023-08-14 |
rat |
| Lakshmi Rajagopal, Mei Huang, Wenqi He, Chelsea Ryan, Ahmad Elzokaky, Pradeep Banerjee, Herbert Y Meltze. Repeated administration of rapastinel produces exceptionally prolonged rescue of memory deficits in phencyclidine-treated mice. Behavioural brain research. 2022-06-19. PMID:35718230. |
both rapastinel (3mg/kg) and ketamine (30mg/kg), moderately increased the efflux of dopamine, norepinephrine, and serotonin in medial prefrontal cortex; however, only ketamine increased cortical glutamate efflux. |
2022-06-19 |
2023-08-14 |
mouse |
| Waisley Yang, Rohit Singla, Oshin Maheshwari, Christine J Fontaine, Joana Gil-Mohape. Alcohol Use Disorder: Neurobiology and Therapeutics. Biomedicines. vol 10. issue 5. 2022-05-28. PMID:35625928. |
ethanol exerts its toxicity through changes to multiple neurotransmitter systems, including serotonin, dopamine, gamma-aminobutyric acid, glutamate, acetylcholine, and opioid systems. |
2022-05-28 |
2023-08-13 |
Not clear |