All Relations between serotonin and 5-ht receptor 1a
| Publication | Sentence | Publish Date | Extraction Date | Species |
|---|---|---|---|---|
| A Pazos, R Cortés, J M Palacio. Quantitative receptor autoradiography: application to the characterization of multiple receptor subtypes. Journal of receptor research. vol 4. issue 1-6. 1985-04-04. PMID:6241253. | in vitro autoradiographic techniques combined with computer assisted microdensitometry were used to analyze the characteristics and distribution of multiple recognition sites for the neurotransmitters acetylcholine (m1 and m2) and serotonin (5-ht1a and 5-ht1b). | 1985-04-04 | 2023-08-12 | Not clear |
| D N Middlemis. 8-Hydroxy-2-(di-n-propylamino) tetralin is devoid of activity at the 5-hydroxytryptamine autoreceptor in rat brain. Implications for the proposed link between the autoreceptor and the [3H] 5-HT recognition site. Naunyn-Schmiedeberg's archives of pharmacology. vol 327. issue 1. 1984-12-05. PMID:6238235. | experiments have been carried out to provide direct evidence for the proposed presynaptic 5-ht autoreceptor agonist activity of 8-hydroxy-2-(di-n-propylamino) tetralin (8-oh-dpat) a compound with selectivity for the 5-ht1a subtype of the 5-ht1 binding site. | 1984-12-05 | 2023-08-12 | rat |
| D N Middlemis. 8-Hydroxy-2-(di-n-propylamino) tetralin is devoid of activity at the 5-hydroxytryptamine autoreceptor in rat brain. Implications for the proposed link between the autoreceptor and the [3H] 5-HT recognition site. Naunyn-Schmiedeberg's archives of pharmacology. vol 327. issue 1. 1984-12-05. PMID:6238235. | moreover, the fact that 8-oh-dpat is inactive at the autoreceptor at concentrations selective for the 5-ht1a recognition site suggests that this subtype of the 5-ht1 binding site may not correspond to the 5-ht autoreceptor. | 1984-12-05 | 2023-08-12 | rat |
| M Hamon, S Bourgoin, H Gozlan, M D Hall, C Goetz, F Artaud, A S Hor. Biochemical evidence for the 5-HT agonist properties of PAT (8-hydroxy-2-(di-n-propylamino)tetralin) in the rat brain. European journal of pharmacology. vol 100. issue 3-4. 1984-08-17. PMID:6203761. | the pat-induced inhibition of [3h]5-ht binding showed marked regional differences compatible with a preferential interaction of pat (ic50 2 nm) with the 5-ht1a subclass. | 1984-08-17 | 2023-08-12 | rat |