| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| b' Martina Lacz\\xc3\\xb3, Jan M Wiener, Jana Kalinova, Veronika Matuskova, Martin Vyhnalek, Jakub Hort, Jan Lacz\\xc3\\xb. Spatial Navigation and Visuospatial Strategies in Typical and Atypical Aging. Brain sciences. vol 11. issue 11. 2021-11-29. PMID:34827423.' |
age-related spatial navigation decline is more pronounced in patients with mild cognitive impairment (mci) and alzheimer's disease (ad) dementia. |
2021-11-29 |
2023-08-13 |
Not clear |
| Anthoni M Goodman, Bethany M Langner, Nateka Jackson, Capri Alex, Lori L McMaho. Heightened Hippocampal β-Adrenergic Receptor Function Drives Synaptic Potentiation and Supports Learning and Memory in the TgF344-AD Rat Model during Prodromal Alzheimer's Disease. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 41. issue 26. 2021-11-22. PMID:33952633. |
the central noradrenergic (na) system is critical for the maintenance of attention, behavioral flexibility, spatial navigation, and learning and memory, those cognitive functions lost first in early alzheimer's disease (ad). |
2021-11-22 |
2023-08-13 |
human |
| Yuduo Zhi, Daniel Co. Neurodegenerative damage reduces firing coherence in a continuous attractor model of grid cells. Physical review. E. vol 104. issue 4-1. 2021-11-16. PMID:34781544. |
the dmec is damaged in the early stages of alzheimer's disease, which affects navigation ability of a disease victim, reducing the synaptic density of neurons in the network. |
2021-11-16 |
2023-08-13 |
Not clear |
| Alina C Stimmell, Zishen Xu, Shawn C Moseley, Sarah D Benthem, Diana M Fernandez, Jessica V Dang, Luis F Santos-Molina, Rosina A Anzalone, Carolina L Garcia-Barbon, Stephany Rodriguez, Jessica R Dixon, Wei Wu, Aaron A Wilbe. Tau Pathology Profile Across a Parietal-Hippocampal Brain Network Is Associated With Spatial Reorientation Learning and Memory Performance in the 3xTg-AD Mouse. Frontiers in aging. vol 2. 2021-11-11. PMID:34746919. |
in early alzheimer's disease (ad) spatial navigation is one of the first impairments to emerge; however, the precise cause of this impairment is unclear. |
2021-11-11 |
2023-08-13 |
mouse |
| Stephanie M Prince, Abigail L Paulson, Nuri Jeong, Lu Zhang, Solange Amigues, Annabelle C Singe. Alzheimer's pathology causes impaired inhibitory connections and reactivation of spatial codes during spatial navigation. Cell reports. vol 35. issue 3. 2021-11-05. PMID:33882308. |
alzheimer's pathology causes impaired inhibitory connections and reactivation of spatial codes during spatial navigation. |
2021-11-05 |
2023-08-13 |
mouse |
| Jan M Wiener, Francesca Pazzagli. Ageing- and dementia-friendly design: theory and evidence from cognitive psychology, neuropsychology and environmental psychology can contribute to design guidelines that minimise spatial disorientation. Cognitive processing. vol 22. issue 4. 2021-10-27. PMID:34047895. |
to facilitate the transition to their new accommodation, it is therefore important to develop retirement complexes and care homes specifically designed to reduce the wayfinding difficulties of older people and those with alzheimer's disease (ad). |
2021-10-27 |
2023-08-13 |
Not clear |
| Jackie M Poos, Ineke J M van der Ham, Anna E Leeuwis, Yolande A L Pijnenburg, Wiesje M van der Flier, Albert Postm. Short Digital Spatial Memory Test Detects Impairment in Alzheimer's Disease and Mild Cognitive Impairment. Brain sciences. vol 11. issue 10. 2021-10-26. PMID:34679414. |
impairment in navigation abilities and object location memory are often seen in early-stage alzheimer's disease (ad), yet these constructs are not included in standard neuropsychological assessment. |
2021-10-26 |
2023-08-13 |
Not clear |
| Jessica Plácido, José Vinicius Ferreira, Juliana Araújo, Felipe de Oliveira Silva, Renan Baltar Ferreira, Carla Guimarães, Andréa Nunes de Carvalho, Jerson Laks, Andrea Camaz Deslande. Beyond the Mini-Mental State Examination: The Use of Physical and Spatial Navigation Tests to Help to Screen for Mild Cognitive Impairment and Alzheimer's Disease. Journal of Alzheimer's disease : JAD. vol 81. issue 3. 2021-09-16. PMID:33935093. |
beyond the mini-mental state examination: the use of physical and spatial navigation tests to help to screen for mild cognitive impairment and alzheimer's disease. |
2021-09-16 |
2023-08-13 |
Not clear |
| Jessica Plácido, José Vinicius Ferreira, Juliana Araújo, Felipe de Oliveira Silva, Renan Baltar Ferreira, Carla Guimarães, Andréa Nunes de Carvalho, Jerson Laks, Andrea Camaz Deslande. Beyond the Mini-Mental State Examination: The Use of Physical and Spatial Navigation Tests to Help to Screen for Mild Cognitive Impairment and Alzheimer's Disease. Journal of Alzheimer's disease : JAD. vol 81. issue 3. 2021-09-16. PMID:33935093. |
spatial navigation and dual-task (dt) performance may represent a low-cost approach to the identification of the cognitive decline in older adults and may support the clinical diagnosis of mild cognitive impairment (mci) and alzheimer's disease (ad). |
2021-09-16 |
2023-08-13 |
Not clear |
| Annakarin Olsson, Kirsti Skovdahl, Maria Engströ. Strategies used by people with Alzheimer's disease for outdoor wayfinding: A repeated observational study. Dementia (London, England). vol 20. issue 2. 2021-07-16. PMID:31874572. |
strategies used by people with alzheimer's disease for outdoor wayfinding: a repeated observational study. |
2021-07-16 |
2023-08-13 |
human |
| Annakarin Olsson, Kirsti Skovdahl, Maria Engströ. Strategies used by people with Alzheimer's disease for outdoor wayfinding: A repeated observational study. Dementia (London, England). vol 20. issue 2. 2021-07-16. PMID:31874572. |
this study aimed to describe the wayfinding strategies used during outdoor walks by people with alzheimer's disease. |
2021-07-16 |
2023-08-13 |
human |
| Annakarin Olsson, Kirsti Skovdahl, Maria Engströ. Strategies used by people with Alzheimer's disease for outdoor wayfinding: A repeated observational study. Dementia (London, England). vol 20. issue 2. 2021-07-16. PMID:31874572. |
using wayfinding strategies might help people with alzheimer's disease to be independent during outdoor walks, and discussing these strategies with relatives and nursing care staff may help finding people with alzheimer's disease if lost outdoors. |
2021-07-16 |
2023-08-13 |
human |
| Annakarin Olsson, Kirsti Skovdahl, Maria Engströ. Strategies used by people with Alzheimer's disease for outdoor wayfinding: A repeated observational study. Dementia (London, England). vol 20. issue 2. 2021-07-16. PMID:31874572. |
wayfinding during the winter might be facilitated if temporary and changeable objects are avoided in people with alzheimer's disease's walking route. |
2021-07-16 |
2023-08-13 |
human |
| Rebecca Davis, Amy Veltkam. Wayfinding Strategies and Spatial Anxiety in Older Adults With and Without Alzheimer's Disease. Research in gerontological nursing. vol 13. issue 2. 2021-07-08. PMID:31697391. |
wayfinding strategies and spatial anxiety in older adults with and without alzheimer's disease. |
2021-07-08 |
2023-08-13 |
human |
| Rebecca Davis, Amy Veltkam. Wayfinding Strategies and Spatial Anxiety in Older Adults With and Without Alzheimer's Disease. Research in gerontological nursing. vol 13. issue 2. 2021-07-08. PMID:31697391. |
persons with alzheimer's disease (ad) often experience problems finding their way (i.e., wayfinding) even in familiar locations. |
2021-07-08 |
2023-08-13 |
human |
| Qian Chen, Zhao Qing, Jiaxuan Jin, Yi Sun, Wenqian Chen, Jiaming Lu, Pin Lv, Jiani Liu, Xin Li, Junxia Wang, Wen Zhang, Sichu Wu, Xian Yan, Zuzana Nedelska, Jakub Hort, Xin Zhang, Bing Zhan. Ego- and allo-network disconnection underlying spatial disorientation in subjective cognitive decline. Cortex; a journal devoted to the study of the nervous system and behavior. vol 137. 2021-07-07. PMID:33588131. |
patients with alzheimer's disease (ad) related dementia and mild cognitive impairment experience difficulties with spatial navigation (sn). |
2021-07-07 |
2023-08-13 |
human |
| Weiping Li, Hui Zhao, Zhao Qing, Zuzana Nedelska, Sichu Wu, Jiaming Lu, Wenbo Wu, Zhenyu Yin, Jakub Hort, Yun Xu, Bing Zhan. Disrupted Network Topology Contributed to Spatial Navigation Impairment in Patients With Mild Cognitive Impairment. Frontiers in aging neuroscience. vol 13. 2021-06-22. PMID:34149391. |
impairment in spatial navigation (sn) and structural network topology is not limited to patients with alzheimer's disease (ad) dementia and can be detected earlier in patients with mild cognitive impairment (mci). |
2021-06-22 |
2023-08-13 |
Not clear |
| Gillian Coughlan, Ryan Larsen, Min Kim, David White, Rachel Gillings, Michael Irvine, Andrew Scholey, Neal Cohen, Cristina Legido-Quigley, Michael Hornberger, Anne-Marie Minihan. Brain communications. vol 3. issue 2. 2021-05-20. PMID:34007965. |
this is despite the fact that spatial navigation deficits are a new cognitive fingerprint for symptomatic and asymptomatic alzheimer's disease. |
2021-05-20 |
2023-08-13 |
human |
| Gillian Coughlan, Ryan Larsen, Min Kim, David White, Rachel Gillings, Michael Irvine, Andrew Scholey, Neal Cohen, Cristina Legido-Quigley, Michael Hornberger, Anne-Marie Minihan. Brain communications. vol 3. issue 2. 2021-05-20. PMID:34007965. |
we investigated the cross-sectional relationship between docosahexaenoic acid levels and the major structural and cognitive markers of preclinical alzheimer's disease, namely hippocampal volume, entorhinal volume and spatial navigation ability. |
2021-05-20 |
2023-08-13 |
human |
| Helena M Gellersen, Gillian Coughlan, Michael Hornberger, Jon S Simon. Memory precision of object-location binding is unimpaired in Brain communications. vol 3. issue 2. 2021-05-17. PMID:33987536. |
memory precision of object-location binding is unimpaired in research suggests that tests of memory fidelity, feature binding and spatial navigation are promising for early detection of subtle behavioural changes related to alzheimer's disease. |
2021-05-17 |
2023-08-13 |
human |