| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Dennis van der Meer, Jaroslav Rokicki, Tobias Kaufmann, Aldo Córdova-Palomera, Torgeir Moberget, Dag Alnæs, Francesco Bettella, Oleksandr Frei, Nhat Trung Doan, Ida E Sønderby, Olav B Smeland, Ingrid Agartz, Alessandro Bertolino, Janita Bralten, Christine L Brandt, Jan K Buitelaar, Srdjan Djurovic, Marjolein van Donkelaar, Erlend S Dørum, Thomas Espeseth, Stephen V Faraone, Guillén Fernández, Simon E Fisher, Barbara Franke, Beathe Haatveit, Catharina A Hartman, Pieter J Hoekstra, Asta K Håberg, Erik G Jönsson, Knut K Kolskår, Stephanie Le Hellard, Martina J Lund, Astri J Lundervold, Arvid Lundervold, Ingrid Melle, Jennifer Monereo Sánchez, Linn C Norbom, Jan E Nordvik, Lars Nyberg, Jaap Oosterlaan, Marco Papalino, Andreas Papassotiropoulos, Giulio Pergola, Dominique J F de Quervain, Geneviève Richard, Anne-Marthe Sanders, Pierluigi Selvaggi, Elena Shumskaya, Vidar M Steen, Siren Tønnesen, Kristine M Ulrichsen, Marcel P Zwiers, Ole A Andreassen, Lars T Westly. Brain scans from 21,297 individuals reveal the genetic architecture of hippocampal subfield volumes. Molecular psychiatry. vol 25. issue 11. 2021-03-15. PMID:30279459. |
these subfields are differentially involved in memory consolidation, spatial navigation and pattern separation, complex functions often impaired in individuals with brain disorders characterized by reduced hippocampal volume, including alzheimer's disease (ad) and schizophrenia. |
2021-03-15 |
2023-08-13 |
Not clear |
| Rebecca Davis, Alla Sikorski. Eye Tracking Analysis of Visual Cues during Wayfinding in Early Stage Alzheimer's Disease. Dementia and geriatric cognitive disorders. vol 49. issue 1. 2021-01-25. PMID:32516764. |
eye tracking analysis of visual cues during wayfinding in early stage alzheimer's disease. |
2021-01-25 |
2023-08-13 |
Not clear |
| Rebecca Davis, Alla Sikorski. Eye Tracking Analysis of Visual Cues during Wayfinding in Early Stage Alzheimer's Disease. Dementia and geriatric cognitive disorders. vol 49. issue 1. 2021-01-25. PMID:32516764. |
persons with alzheimer's disease (ad) have profound impairment in wayfinding, potentially related to a deficit in visual attention and selection of relevant environmental information. |
2021-01-25 |
2023-08-13 |
Not clear |
| Taylor F Levine, Samantha L Allison, Marta Stojanovic, Anne M Fagan, John C Morris, Denise Hea. Spatial navigation ability predicts progression of dementia symptomatology. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 16. issue 3. 2020-11-26. PMID:32043719. |
spatial navigation deficits are observed in alzheimer's disease cross-sectionally, but prediction of longitudinal clinical decline has been less examined. |
2020-11-26 |
2023-08-13 |
Not clear |
| Alina C Stimmell, David Baglietto-Vargas, Shawn C Moseley, Valérie Lapointe, Lauren M Thompson, Frank M LaFerla, Bruce L McNaughton, Aaron A Wilbe. Impaired Spatial Reorientation in the 3xTg-AD Mouse Model of Alzheimer's Disease. Scientific reports. vol 9. issue 1. 2020-11-12. PMID:30718609. |
in early alzheimer's disease (ad) spatial navigation is impaired; however, the precise cause of this impairment is unclear. |
2020-11-12 |
2023-08-13 |
mouse |
| Gillian Coughlan, Vaisakh Puthusseryppady, Ellen Lowry, Rachel Gillings, Hugo Spiers, Anne-Marie Minihane, Michael Hornberge. Test-retest reliability of spatial navigation in adults at-risk of Alzheimer's disease. PloS one. vol 15. issue 9. 2020-11-04. PMID:32960930. |
test-retest reliability of spatial navigation in adults at-risk of alzheimer's disease. |
2020-11-04 |
2023-08-13 |
human |
| Gillian Coughlan, Peter Zhukovsky, Vaisakh Puthusseryppady, Rachel Gillings, Anne-Marie Minihane, Donnie Cameron, Michael Hornberge. Functional connectivity between the entorhinal and posterior cingulate cortices underpins navigation discrepancies in at-risk Alzheimer's disease. Neurobiology of aging. vol 90. 2020-10-29. PMID:32171591. |
functional connectivity between the entorhinal and posterior cingulate cortices underpins navigation discrepancies in at-risk alzheimer's disease. |
2020-10-29 |
2023-08-13 |
Not clear |
| Gillian Coughlan, Peter Zhukovsky, Vaisakh Puthusseryppady, Rachel Gillings, Anne-Marie Minihane, Donnie Cameron, Michael Hornberge. Functional connectivity between the entorhinal and posterior cingulate cortices underpins navigation discrepancies in at-risk Alzheimer's disease. Neurobiology of aging. vol 90. 2020-10-29. PMID:32171591. |
navigation processes that are selectively mediated by functional activity in the entorhinal cortex may be a marker of preclinical alzheimer's disease (ad). |
2020-10-29 |
2023-08-13 |
Not clear |
| Paul J F White, Zahra Moussav. Neurocognitive Treatment for a Patient with Alzheimer's Disease Using a Virtual Reality Navigational Environment. Journal of experimental neuroscience. vol 10. 2020-09-30. PMID:27840579. |
in this case study, a man at the onset of alzheimer's disease (ad) was enrolled in a cognitive treatment program based upon spatial navigation in a virtual reality (vr) environment. |
2020-09-30 |
2023-08-13 |
human |
| Ellen Lowry, Vaisakh Puthusseryppady, Gillian Coughlan, Stephen Jeffs, Michael Hornberge. Path Integration Changes as a Cognitive Marker for Vascular Cognitive Impairment?-A Pilot Study. Frontiers in human neuroscience. vol 14. 2020-09-28. PMID:32372934. |
path integration spatial navigation processes are emerging as promising cognitive markers for prodromal and clinical alzheimer's disease (ad). |
2020-09-28 |
2023-08-13 |
Not clear |
| Carolyn A Unsworth, Kay Russell, Robin Lovell, Michael Woodward, Matthew Brown. Effect of Navigation Problems, Assessment Location, and a Practice Test on Driving Assessment Performance for People with Alzheimer's Disease. Journal of Alzheimer's disease : JAD. vol 67. issue 3. 2020-05-29. PMID:30776013. |
effect of navigation problems, assessment location, and a practice test on driving assessment performance for people with alzheimer's disease. |
2020-05-29 |
2023-08-13 |
Not clear |
| Gillian Coughlan, Antoine Coutrot, Mizanur Khondoker, Anne-Marie Minihane, Hugo Spiers, Michael Hornberge. Toward personalized cognitive diagnostics of at-genetic-risk Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. vol 116. issue 19. 2020-03-26. PMID:31015296. |
spatial navigation is emerging as a critical factor in identifying preclinical alzheimer's disease (ad). |
2020-03-26 |
2023-08-13 |
Not clear |
| David Howett, Andrea Castegnaro, Katarzyna Krzywicka, Johanna Hagman, Deepti Marchment, Richard Henson, Miguel Rio, John A King, Neil Burgess, Dennis Cha. Differentiation of mild cognitive impairment using an entorhinal cortex-based test of virtual reality navigation. Brain : a journal of neurology. vol 142. issue 6. 2020-03-12. PMID:31121601. |
this study tested the hypothesis that entorhinal-based navigation is impaired in pre-dementia alzheimer's disease. |
2020-03-12 |
2023-08-13 |
human |
| David Howett, Andrea Castegnaro, Katarzyna Krzywicka, Johanna Hagman, Deepti Marchment, Richard Henson, Miguel Rio, John A King, Neil Burgess, Dennis Cha. Differentiation of mild cognitive impairment using an entorhinal cortex-based test of virtual reality navigation. Brain : a journal of neurology. vol 142. issue 6. 2020-03-12. PMID:31121601. |
forty-five patients with mild cognitive impairment (26 with csf alzheimer's disease biomarker data: 12 biomarker-positive and 14 biomarker-negative) and 41 healthy control participants undertook an immersive virtual reality path integration test, as a measure of entorhinal-based navigation. |
2020-03-12 |
2023-08-13 |
human |
| David Howett, Andrea Castegnaro, Katarzyna Krzywicka, Johanna Hagman, Deepti Marchment, Richard Henson, Miguel Rio, John A King, Neil Burgess, Dennis Cha. Differentiation of mild cognitive impairment using an entorhinal cortex-based test of virtual reality navigation. Brain : a journal of neurology. vol 142. issue 6. 2020-03-12. PMID:31121601. |
this study demonstrates that an entorhinal cortex-based virtual reality navigation task can differentiate patients with mild cognitive impairment at low and high risk of developing dementia, with classification accuracy superior to reference cognitive tests considered to be highly sensitive to early alzheimer's disease. |
2020-03-12 |
2023-08-13 |
human |
| David Howett, Andrea Castegnaro, Katarzyna Krzywicka, Johanna Hagman, Deepti Marchment, Richard Henson, Miguel Rio, John A King, Neil Burgess, Dennis Cha. Differentiation of mild cognitive impairment using an entorhinal cortex-based test of virtual reality navigation. Brain : a journal of neurology. vol 142. issue 6. 2020-03-12. PMID:31121601. |
this study provides evidence that navigation tasks may aid early diagnosis of alzheimer's disease, and the basis of this in animal cellular and behavioural studies provides the opportunity to answer the unmet need for translatable outcome measures for comparing treatment effect across preclinical and clinical trial phases of future anti-alzheimer's drugs. |
2020-03-12 |
2023-08-13 |
human |
| Samantha L Allison, Thomas L Rodebaugh, Chiharu Johnston, Anne M Fagan, John C Morris, Denise Hea. Developing a Spatial Navigation Screening Tool Sensitive to the Preclinical Alzheimer Disease Continuum. Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists. vol 34. issue 7. 2020-02-10. PMID:31197326. |
developing a spatial navigation screening tool sensitive to the preclinical alzheimer disease continuum. |
2020-02-10 |
2023-08-13 |
Not clear |
| Jan Laczó, Martina Parizkova, Scott D Moffa. Spatial navigation, aging and Alzheimer's disease. Aging. vol 10. issue 11. 2019-12-19. PMID:30393235. |
spatial navigation, aging and alzheimer's disease. |
2019-12-19 |
2023-08-13 |
Not clear |
| Antoine Coutrot, Sophie Schmidt, Lena Coutrot, Jessica Pittman, Lynn Hong, Jan M Wiener, Christoph Hölscher, Ruth C Dalton, Michael Hornberger, Hugo J Spier. Virtual navigation tested on a mobile app is predictive of real-world wayfinding navigation performance. PloS one. vol 14. issue 3. 2019-12-13. PMID:30883560. |
virtual reality environments presented on tablets and smartphones have potential to aid the early diagnosis of conditions such as alzheimer's dementia by quantifying impairments in navigation performance. |
2019-12-13 |
2023-08-13 |
human |
| Quentin Lenoble, Xavier Corveleyn, Sébastien Szaffarczyk, Florence Pasquier, Muriel Boucar. Attentional capture by incongruent object/background scenes in patients with Alzheimer disease. Cortex; a journal devoted to the study of the nervous system and behavior. vol 107. 2019-11-26. PMID:30006000. |
patients with alzheimer disease (ad) exhibit impairment in scene processing at different levels: perception, recognition, memory and spatial navigation. |
2019-11-26 |
2023-08-13 |
Not clear |