| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Carla Velarde, Elizabeth Perelstein, Wendy Ressmann, Charles J Duff. Independent deficits of visual word and motion processing in aging and early Alzheimer's disease. Journal of Alzheimer's disease : JAD. vol 31. issue 3. 2013-05-21. PMID:22647256. |
we tested whether visual processing impairments in aging and alzheimer's disease (ad) reflect uniform posterior cortical decline, or independent disorders of visual processing for reading and navigation. |
2013-05-21 |
2023-08-12 |
human |
| Heikki Tanil. Wading pools, fading memories-place navigation in transgenic mouse models of Alzheimer's disease. Frontiers in aging neuroscience. vol 4. 2012-10-02. PMID:22670146. |
wading pools, fading memories-place navigation in transgenic mouse models of alzheimer's disease. |
2012-10-02 |
2023-08-12 |
mouse |
| Ivana Gazova, Kamil Vlcek, Jan Laczó, Zuzana Nedelska, Eva Hyncicova, Ivana Mokrisova, Katerina Sheardova, Jakub Hor. Spatial navigation-a unique window into physiological and pathological aging. Frontiers in aging neuroscience. vol 4. 2012-10-02. PMID:22737124. |
nevertheless, severe spatial navigation deficit can be the first sign of incipient alzheimer's disease (ad), occurring in the stage of mild cognitive impairment (mci), preceding the development of a full blown dementia. |
2012-10-02 |
2023-08-12 |
Not clear |
| J Laczó, R Andel, M Vyhnalek, K Vlcek, H Magerova, A Varjassyova, Z Nedelska, I Gazova, M Bojar, K Sheardova, J Hor. From Morris Water Maze to computer tests in the prediction of Alzheimer's disease. Neuro-degenerative diseases. vol 10. issue 1-4. 2012-08-29. PMID:22205134. |
spatial navigation performance in the hidden goal task (hgt), a real-space human analogue of the morris water maze, can identify amnestic mild cognitive impairment (amci) patients with memory impairment of the hippocampal type, a known indicator of incipient alzheimer's disease (ad). |
2012-08-29 |
2023-08-12 |
human |
| Virginie Bellassen, Kinga Iglói, Leonardo Cruz de Souza, Bruno Dubois, Laure Rondi-Rei. Temporal order memory assessed during spatiotemporal navigation as a behavioral cognitive marker for differential Alzheimer's disease diagnosis. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 6. 2012-03-27. PMID:22323707. |
temporal order memory assessed during spatiotemporal navigation as a behavioral cognitive marker for differential alzheimer's disease diagnosis. |
2012-03-27 |
2023-08-12 |
human |
| Virginie Bellassen, Kinga Iglói, Leonardo Cruz de Souza, Bruno Dubois, Laure Rondi-Rei. Temporal order memory assessed during spatiotemporal navigation as a behavioral cognitive marker for differential Alzheimer's disease diagnosis. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 6. 2012-03-27. PMID:22323707. |
we used a newly developed, nonverbal navigation test for human, based on the objective experimental testing of a spatiotemporal experience, to differentially alzheimer's disease at the mild stage (n = 16 patients) from frontotemporal lobar degeneration (n = 11 patients) and normal aging (n = 24 subjects). |
2012-03-27 |
2023-08-12 |
human |
| Virginie Bellassen, Kinga Iglói, Leonardo Cruz de Souza, Bruno Dubois, Laure Rondi-Rei. Temporal order memory assessed during spatiotemporal navigation as a behavioral cognitive marker for differential Alzheimer's disease diagnosis. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 6. 2012-03-27. PMID:22323707. |
comparing navigation parameters and standard neuropsychological tests, temporal order memory appeared to have the highest predictive power for mild alzheimer's disease diagnosis versus frontotemporal lobar degeneration and normal aging. |
2012-03-27 |
2023-08-12 |
human |
| Virginie Bellassen, Kinga Iglói, Leonardo Cruz de Souza, Bruno Dubois, Laure Rondi-Rei. Temporal order memory assessed during spatiotemporal navigation as a behavioral cognitive marker for differential Alzheimer's disease diagnosis. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 6. 2012-03-27. PMID:22323707. |
as a conclusion, our results suggest that temporal order memory tested in a spatial navigation task may provide a selective behavioral marker of alzheimer's disease. |
2012-03-27 |
2023-08-12 |
human |
| Voyko Kavcic, William Vaughn, Charles J Duff. Distinct visual motion processing impairments in aging and Alzheimer's disease. Vision research. vol 51. issue 3. 2011-08-12. PMID:21156185. |
aging and alzheimer's disease (ad) are associated with declines in the visual perception of self-movement that undermine navigation and independent living. |
2011-08-12 |
2023-08-12 |
human |
| Roy P C Kessels, Amy van Doormaal, Gabriele Janze. Landmark recognition in Alzheimer's dementia: spared implicit memory for objects relevant for navigation. PloS one. vol 6. issue 4. 2011-07-20. PMID:21483699. |
landmark recognition in alzheimer's dementia: spared implicit memory for objects relevant for navigation. |
2011-07-20 |
2023-08-12 |
Not clear |
| Roy P C Kessels, Amy van Doormaal, Gabriele Janze. Landmark recognition in Alzheimer's dementia: spared implicit memory for objects relevant for navigation. PloS one. vol 6. issue 4. 2011-07-20. PMID:21483699. |
since there is evidence that implicit learning is intact in amnesic patients, the current study examined memory for objects relevant for navigation in patients with alzheimer's dementia (ad). |
2011-07-20 |
2023-08-12 |
Not clear |
| Oliver Baumann, Jason B Mattingle. Medial parietal cortex encodes perceived heading direction in humans. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 39. 2010-10-25. PMID:20881108. |
our findings also help to explain why navigation disturbances are commonly observed in patients with alzheimer's disease, whose pathology typically includes the cortical region we have identified as being crucial for maintaining representations of heading direction. |
2010-10-25 |
2023-08-12 |
human |
| Mark Mapstone, Charles J Duff. Approaching objects cause confusion in patients with Alzheimer's disease regarding their direction of self-movement. Brain : a journal of neurology. vol 133. issue 9. 2010-09-20. PMID:20647265. |
the tendency to be confused by objects that appear to move independently in the simulated visual scene corresponded to the difficulty patients with alzheimer's disease encountered in real-world navigation through the hospital lobby (r(2) = 0.87). |
2010-09-20 |
2023-08-12 |
human |
| Mark Mapstone, Charles J Duff. Approaching objects cause confusion in patients with Alzheimer's disease regarding their direction of self-movement. Brain : a journal of neurology. vol 133. issue 9. 2010-09-20. PMID:20647265. |
we conclude that perceptual factors limit safe, autonomous navigation in early alzheimer's disease. |
2010-09-20 |
2023-08-12 |
human |
| Charles J Duff. Visual motion processing in aging and Alzheimer's disease: neuronal mechanisms and behavior from monkeys to man. Annals of the New York Academy of Sciences. vol 1170. 2009-09-25. PMID:19686221. |
aging and alzheimer's disease (ad) are accompanied by impairments of autonomous navigation and spatial orientation that commonly demand the abandonment of driving and independent living. |
2009-09-25 |
2023-08-12 |
human |
| Bruce Fischl, Allison A Stevens, Niranjini Rajendran, B T Thomas Yeo, Douglas N Greve, Koen Van Leemput, Jonathan R Polimeni, Sita Kakunoori, Randy L Buckner, Jennifer Pacheco, David H Salat, Jennifer Melcher, Matthew P Frosch, Bradley T Hyman, P Ellen Grant, Bruce R Rosen, André J W van der Kouwe, Graham C Wiggins, Lawrence L Wald, Jean C Augustinac. Predicting the location of entorhinal cortex from MRI. NeuroImage. vol 47. issue 1. 2009-08-24. PMID:19376238. |
entorhinal cortex (ec) is a medial temporal lobe area critical to memory formation and spatial navigation that is among the earliest parts of the brain affected by alzheimer's disease (ad). |
2009-08-24 |
2023-08-12 |
Not clear |
| Sheng-Siang Jheng, Ming-Chyi Pa. Cognitive map in patients with mild Alzheimer's disease: a computer-generated arena study. Behavioural brain research. vol 200. issue 1. 2009-06-18. PMID:19162077. |
cognitive map in patients with mild alzheimer's disease: a computer-generated arena study. |
2009-06-18 |
2023-08-12 |
Not clear |
| Brian R Ott, Elena K Festa, Melissa M Amick, Janet Grace, Jennifer D Davis, William C Heinde. Computerized maze navigation and on-road performance by drivers with dementia. Journal of geriatric psychiatry and neurology. vol 21. issue 1. 2008-05-13. PMID:18287166. |
as a visual analog of driving, a brief computerized test of maze navigation time compares well to standard neuropsychological tests of psychomotor speed, scanning, attention, and working memory as a predictor of driving performance by persons with early alzheimer disease and normal elders. |
2008-05-13 |
2023-08-12 |
human |
| Christopher Jo Baker, Rajaraman Kanagasabai, Wee Tiong Ang, Anitha Veeramani, Hong-Sang Low, Markus R Wen. Towards ontology-driven navigation of the lipid bibliosphere. BMC bioinformatics. vol 9 Suppl 1. 2008-04-11. PMID:18315858. |
in the emerging field of lipidomics such navigation challenges are barriers to the translation of scientific results into actionable knowledge, critical to the treatment of diseases such as alzheimer's syndrome, mycobacterium infections and cancer. |
2008-04-11 |
2023-08-12 |
Not clear |
| Amy R Deipolyi, Shanna Fang, Jorge J Palop, Gui-Qiu Yu, Xin Wang, Lennart Muck. Altered navigational strategy use and visuospatial deficits in hAPP transgenic mice. Neurobiology of aging. vol 29. issue 2. 2008-02-21. PMID:17126954. |
navigation deficits are prominent in alzheimer's disease (ad) patients and transgenic mice expressing familial ad-mutant happ and a beta peptides. |
2008-02-21 |
2023-08-12 |
mouse |