| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zhao Qing, Weiping Li, Zuzana Nedelska, Wenbo Wu, Fangfang Wang, Renyuan Liu, Hui Zhao, Weibo Chen, Queenie Chan, Bin Zhu, Yun Xu, Jakub Hort, Bing Zhan. Spatial Navigation Impairment Is Associated with Alterations in Subcortical Intrinsic Activity in Mild Cognitive Impairment: A Resting-State fMRI Study. Behavioural neurology. vol 2017. 2018-01-31. PMID:29085184. |
impairment of spatial navigation (sn) skills is one of the features of the alzheimer's disease (ad) already at the stage of mild cognitive impairment (mci). |
2018-01-31 |
2023-08-13 |
Not clear |
| Jan Laczó, Ross Andel, Zuzana Nedelska, Martin Vyhnalek, Kamil Vlcek, Sebastian Crutch, John Harrison, Jakub Hor. Exploring the contribution of spatial navigation to cognitive functioning in older adults. Neurobiology of aging. vol 51. 2017-09-28. PMID:28039765. |
spatial navigation (sn) impairment is present early in alzheimer's disease (ad). |
2017-09-28 |
2023-08-13 |
Not clear |
| Mary O'Malley, Anthea Innes, Jan M Wiene. Decreasing spatial disorientation in care-home settings: How psychology can guide the development of dementia friendly design guidelines. Dementia (London, England). vol 16. issue 3. 2017-04-27. PMID:26112167. |
alzheimer's disease results in marked declines in navigation skills that are particularly pronounced in unfamiliar environments. |
2017-04-27 |
2023-08-13 |
Not clear |
| Szabolcs Kér. How assistive technology changes the brain: the critical role of hippocampal-striatal interactions during cognitive training. Studies in health technology and informatics. vol 217. 2017-04-24. PMID:26294535. |
in this study, we show that extensive training with a platformer game simulating navigation and real-life spatial abilities, patients with alzheimer's disease and amnestic mild cognitive impairmant exhibit an increased volume of the caudate nucleus in contrast to healthy individuals who display increased hippocampal volumes. |
2017-04-24 |
2023-08-13 |
Not clear |
| Rosalam Che Me, Alessandro Biamonti, Mohd Rashid Mohd Saa. Conceptual Design of Haptic-Feedback Navigation Device for Individuals with Alzheimer's Disease. Studies in health technology and informatics. vol 217. 2017-04-14. PMID:26294473. |
conceptual design of haptic-feedback navigation device for individuals with alzheimer's disease. |
2017-04-14 |
2023-08-13 |
Not clear |
| Rosalam Che Me, Alessandro Biamonti, Mohd Rashid Mohd Saa. Conceptual Design of Haptic-Feedback Navigation Device for Individuals with Alzheimer's Disease. Studies in health technology and informatics. vol 217. 2017-04-14. PMID:26294473. |
wayfinding ability in older adults with alzheimer's disease (ad) is progressively impaired due to ageing and deterioration of cognitive domains. |
2017-04-14 |
2023-08-13 |
Not clear |
| Rebecca Davis, Catherine Weisbec. Creating a Supportive Environment Using Cues for Wayfinding in Dementia. Journal of gerontological nursing. vol 42. issue 3. 2017-03-07. PMID:26934972. |
the ability to find one's way in the world, known as wayfinding, is impaired in individuals with alzheimer's disease (ad). |
2017-03-07 |
2023-08-13 |
Not clear |
| Eilon Casp. Wayfinding difficulties among elders with dementia in an assisted living residence. Dementia (London, England). vol 13. issue 4. 2017-02-03. PMID:24858550. |
the concerning phenomena of spatial disorientation and wayfinding difficulties among elders with alzheimer's disease or a related dementia in assisted living residences are understudied. |
2017-02-03 |
2023-08-13 |
human |
| Samantha L Allison, Anne M Fagan, John C Morris, Denise Hea. Spatial Navigation in Preclinical Alzheimer's Disease. Journal of Alzheimer's disease : JAD. vol 52. issue 1. 2017-01-27. PMID:26967209. |
spatial navigation in preclinical alzheimer's disease. |
2017-01-27 |
2023-08-13 |
Not clear |
| Laurence Paire-Ficout, Claude Marin-Lamellet, Sylviane Lafont, Catherine Thomas-Antérion, Bernard Lauren. The role of navigation instruction at intersections for older drivers and those with early Alzheimer's disease. Accident; analysis and prevention. vol 96. 2017-01-02. PMID:27552136. |
the role of navigation instruction at intersections for older drivers and those with early alzheimer's disease. |
2017-01-02 |
2023-08-13 |
Not clear |
| Erminia Gadler, Alessandra Grassi, Giuseppe Riv. A Rehabilitation Protocol for Empowering Spatial Orientation in MCI. A Pilot Study. Studies in health technology and informatics. vol 144. 2016-04-23. PMID:19592770. |
spatial navigation is among the first cognitive functions to be impaired in alzheimer's disease [1] and deficit in this domain is detectable earlier in patients with mild cognitive impairment [2]. |
2016-04-23 |
2023-08-12 |
Not clear |
| Gro Gujord Tangen, Knut Engedal, Astrid Bergland, Tron Anders Moger, Oskar Hansson, Anne Marit Mengshoe. Spatial navigation measured by the Floor Maze Test in patients with subjective cognitive impairment, mild cognitive impairment, and mild Alzheimer's disease. International psychogeriatrics. vol 27. issue 8. 2016-04-18. PMID:25644091. |
spatial navigation measured by the floor maze test in patients with subjective cognitive impairment, mild cognitive impairment, and mild alzheimer's disease. |
2016-04-18 |
2023-08-13 |
Not clear |
| Gro Gujord Tangen, Knut Engedal, Astrid Bergland, Tron Anders Moger, Oskar Hansson, Anne Marit Mengshoe. Spatial navigation measured by the Floor Maze Test in patients with subjective cognitive impairment, mild cognitive impairment, and mild Alzheimer's disease. International psychogeriatrics. vol 27. issue 8. 2016-04-18. PMID:25644091. |
impaired spatial navigation is an early sign of alzheimer's disease (ad), but this can be difficult to assess in clinical practice. |
2016-04-18 |
2023-08-13 |
Not clear |
| Georg M Kerbler, Zuzana Nedelska, Jurgen Fripp, Jan Laczó, Martin Vyhnalek, Jiří Lisý, Adam S Hamlin, Stephen Rose, Jakub Hort, Elizabeth J Coulso. Basal Forebrain Atrophy Contributes to Allocentric Navigation Impairment in Alzheimer's Disease Patients. Frontiers in aging neuroscience. vol 7. 2015-10-07. PMID:26441643. |
basal forebrain atrophy contributes to allocentric navigation impairment in alzheimer's disease patients. |
2015-10-07 |
2023-08-13 |
human |
| Edvard Moser, May-Britt Mose. Mapping your every move. Cerebrum : the Dana forum on brain science. vol 2014. 2014-07-10. PMID:25009694. |
because the entorhinal cortex, which contains the grid-cell navigation system, is often damaged in the early stages of alzheimer's disease, future research to better understand how cognitive ability and memory are lost has great potential significance for the treatment of alzheimer's and other neurological disorders. |
2014-07-10 |
2023-08-13 |
Not clear |
| b' Kamil Vl\\xc4\\x8dek, Jan Lacz\\xc3\\xb. Neural correlates of spatial navigation changes in mild cognitive impairment and Alzheimer\'s disease. Frontiers in behavioral neuroscience. vol 8. 2014-04-21. PMID:24672452.' |
neural correlates of spatial navigation changes in mild cognitive impairment and alzheimer's disease. |
2014-04-21 |
2023-08-12 |
Not clear |
| Ivana Gazova, Jan Laczó, Eva Rubinova, Ivana Mokrisova, Eva Hyncicova, Ross Andel, Martin Vyhnalek, Katerina Sheardova, Elizabeth J Coulson, Jakub Hor. Spatial navigation in young versus older adults. Frontiers in aging neuroscience. vol 5. 2014-01-06. PMID:24391585. |
this specific pattern of spatial navigation impairment may help differentiate normal aging from prodromal alzheimer's disease. |
2014-01-06 |
2023-08-12 |
human |
| Adam S Hamlin, Francois Windels, Zoran Boskovic, Pankaj Sah, Elizabeth J Coulso. Lesions of the basal forebrain cholinergic system in mice disrupt idiothetic navigation. PloS one. vol 8. issue 1. 2013-08-15. PMID:23320088. |
it is also known that alzheimer's disease patients perform poorly on both real space and computerized cued (allothetic) or uncued (idiothetic) recall navigation tasks. |
2013-08-15 |
2023-08-12 |
mouse |
| Adam S Hamlin, Francois Windels, Zoran Boskovic, Pankaj Sah, Elizabeth J Coulso. Lesions of the basal forebrain cholinergic system in mice disrupt idiothetic navigation. PloS one. vol 8. issue 1. 2013-08-15. PMID:23320088. |
these data suggest that the basal forebrain cholinergic system plays a specific role in idiothetic navigation, a modality that is impaired early in alzheimer's disease. |
2013-08-15 |
2023-08-12 |
mouse |
| Ségolène Lithfous, André Dufour, Olivier Despré. Spatial navigation in normal aging and the prodromal stage of Alzheimer's disease: insights from imaging and behavioral studies. Ageing research reviews. vol 12. issue 1. 2013-06-25. PMID:22771718. |
spatial navigation in normal aging and the prodromal stage of alzheimer's disease: insights from imaging and behavioral studies. |
2013-06-25 |
2023-08-12 |
Not clear |