| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S I Harik, M J Mitchell, R N Kalari. Ouabain binding in the human brain. Effects of Alzheimer's disease and aging. Archives of neurology. vol 46. issue 9. 1989-09-26. PMID:2549926. |
we studied na+,k+-adenosine triphosphatase by assaying specific tritiated ouabain binding in the frontal cortex, temporal cortex, hippocampus, putamen, cerebellum, and cerebral microvessels in subjects with alzheimer's disease and control subjects. |
1989-09-26 |
2023-08-11 |
human |
| S I Harik, M J Mitchell, R N Kalari. Ouabain binding in the human brain. Effects of Alzheimer's disease and aging. Archives of neurology. vol 46. issue 9. 1989-09-26. PMID:2549926. |
ouabain binding was also significantly decreased in the cerebellum and putamen of subjects with alzheimer's disease even though these brain regions are not particularly affected in this disease. |
1989-09-26 |
2023-08-11 |
human |
| S Mita, E A Schon, J Herber. Widespread expression of amyloid beta-protein precursor gene in rat brain. The American journal of pathology. vol 134. issue 6. 1989-09-07. PMID:2502926. |
because the cerebellum is relatively uninvolved in alzheimer's disease, these findings suggest that high intraneuronal expression of abpp may be a necessary but not sufficient requirement for plaque formation. |
1989-09-07 |
2023-08-11 |
human |
| N S Langstrom, J P Anderson, H G Lindroos, B Winblad, W C Wallac. Alzheimer's disease-associated reduction of polysomal mRNA translation. Brain research. Molecular brain research. vol 5. issue 4. 1989-08-17. PMID:2747450. |
these differences exhibited brain region specificity in that polysomes isolated from alzheimer's disease cerebellum were not different from control cerebellar polysomes. |
1989-08-17 |
2023-08-11 |
human |
| C Bancher, I Grundke-Iqbal, K Iqbal, K S Kim, H M Wisniewsk. Immunoreactivity of neuronal lipofuscin with monoclonal antibodies to the amyloid beta-protein. Neurobiology of aging. vol 10. issue 2. 1989-06-26. PMID:2657463. |
staining of lipofuscin is observed in both cerebral and cerebellar cortices, subcortical nuclei as well as the brain stem, and is identical in alzheimer and normal control brain. |
1989-06-26 |
2023-08-11 |
Not clear |
| R A Stern, L Otvos, J Q Trojanowski, V M Le. Monoclonal antibodies to a synthetic peptide homologous with the first 28 amino acids of Alzheimer's disease beta-protein recognize amyloid and diverse glial and neuronal cell types in the central nervous system. The American journal of pathology. vol 134. issue 5. 1989-06-20. PMID:2524164. |
using rabbit and mouse antisera, and 7 mabs, sections of neocortex, hippocampus, cerebellum, and spinal cord from alzheimer's disease (ad), down's syndrome (ds), and control cases were probed. |
1989-06-20 |
2023-08-11 |
mouse |
| A Delacourte, L Bué. [Alzheimer's disease: the glial reaction is general and severe in all areas of the central nervous system]. Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie. vol 308. issue 13. 1989-06-15. PMID:2496895. |
moreover, there was a 11 fold gfap increase (p less than 0.001) in the other regions of the alzheimer brains that do not present the alzheimer pathology, such as caudate nucleus, cerebellum or brain stem. |
1989-06-15 |
2023-08-11 |
Not clear |
| H Akiyama, R Harrop, P L McGeer, R Peppard, E G McGee. Crossed cerebellar and uncrossed basal ganglia and thalamic diaschisis in Alzheimer's disease. Neurology. vol 39. issue 4. 1989-05-10. PMID:2784550. |
crossed cerebellar and uncrossed basal ganglia and thalamic diaschisis in alzheimer's disease. |
1989-05-10 |
2023-08-11 |
human |
| H Akiyama, R Harrop, P L McGeer, R Peppard, E G McGee. Crossed cerebellar and uncrossed basal ganglia and thalamic diaschisis in Alzheimer's disease. Neurology. vol 39. issue 4. 1989-05-10. PMID:2784550. |
we detected crossed cerebellar as well as uncrossed basal ganglia and thalamic diaschisis in alzheimer's disease by positron emission tomography (pet) using 18f-fluorodeoxyglucose. |
1989-05-10 |
2023-08-11 |
human |
| H Akiyama, R Harrop, P L McGeer, R Peppard, E G McGee. Crossed cerebellar and uncrossed basal ganglia and thalamic diaschisis in Alzheimer's disease. Neurology. vol 39. issue 4. 1989-05-10. PMID:2784550. |
for the alzheimer group, we found cerebellar ais correlated negatively, and thalamic ais positively, with those of the cerebral hemisphere and frontal, temporal, parietal, and angular cortices, while basal ganglia ais correlated positively with frontal cortical ais. |
1989-05-10 |
2023-08-11 |
human |
| F Gra. [The neuropathology of Parkinson syndrome]. Revue neurologique. vol 144. issue 4. 1988-10-14. PMID:2843979. |
however, changes in the sn at the origin of parkinsonism are occasionally found in cortical degenerative diseases such as senile dementia of alzheimer's type, pick disease or the complex of guam, in cerebellar atrophies or in motor neuron disease. |
1988-10-14 |
2023-08-11 |
Not clear |
| J Lowe, A Blanchard, K Morrell, G Lennox, L Reynolds, M Billett, M Landon, R J Maye. Ubiquitin is a common factor in intermediate filament inclusion bodies of diverse type in man, including those of Parkinson's disease, Pick's disease, and Alzheimer's disease, as well as Rosenthal fibres in cerebellar astrocytomas, cytoplasmic bodies in muscle, and mallory bodies in alcoholic liver disease. The Journal of pathology. vol 155. issue 1. 1988-07-21. PMID:2837558. |
ubiquitin is a common factor in intermediate filament inclusion bodies of diverse type in man, including those of parkinson's disease, pick's disease, and alzheimer's disease, as well as rosenthal fibres in cerebellar astrocytomas, cytoplasmic bodies in muscle, and mallory bodies in alcoholic liver disease. |
1988-07-21 |
2023-08-11 |
Not clear |
| A Klinger, M J de Leon, A E George, J D Miller, A P Wol. Elevated cerebellar glucose metabolism in microvascular white matter disease: normal aging and Alzheimer's disease. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 8. issue 3. 1988-06-20. PMID:3259243. |
elevated cerebellar glucose metabolism in microvascular white matter disease: normal aging and alzheimer's disease. |
1988-06-20 |
2023-08-11 |
human |
| A Klinger, M J de Leon, A E George, J D Miller, A P Wol. Elevated cerebellar glucose metabolism in microvascular white matter disease: normal aging and Alzheimer's disease. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 8. issue 3. 1988-06-20. PMID:3259243. |
young normal, elderly, and clinically diagnosed alzheimer disease subjects who had undergone positron emission tomography (pet) and computed tomography (ct) examinations were studied to determine the effect of periventricular white matter lesions on cerebellar glucose metabolic rates. |
1988-06-20 |
2023-08-11 |
human |
| M Kushner, M Tobin, A Alavi, J Chawluk, M Rosen, F Fazekas, J Alavi, M Reivic. Cerebellar glucose consumption in normal and pathologic states using fluorine-FDG and PET. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. vol 28. issue 11. 1987-12-14. PMID:3499490. |
we studied cerebellar metabolism in 118 subjects including young and elderly controls and patients suffering from stroke, supratentorial brain tumor and alzheimer's disease using fluorine-18 fluorodeoxyglucose ([18f]fdg) and position emission tomography (pet). |
1987-12-14 |
2023-08-11 |
human |
| M Kushner, M Tobin, A Alavi, J Chawluk, M Rosen, F Fazekas, J Alavi, M Reivic. Cerebellar glucose consumption in normal and pathologic states using fluorine-FDG and PET. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. vol 28. issue 11. 1987-12-14. PMID:3499490. |
alzheimer's disease and normal aging did not alter mean cerebellar metabolism. |
1987-12-14 |
2023-08-11 |
human |
| W J Burke, H D Chung, B R Nakra, G T Grossberg, T H Jo. Phenylethanolamine N-methyltransferase activity is decreased in Alzheimer's disease brains. Annals of neurology. vol 22. issue 2. 1987-11-10. PMID:3662456. |
we now report on 5 patients with alzheimer's disease (ad) who had a decrease in pnmt activity of 37 to 48% in areas of the brain affected by the disease but not in the cerebellum, an area of the brain unaffected by the disease. |
1987-11-10 |
2023-08-11 |
human |
| S Kobayashi, N Hirota, K Saito, M Utsuyam. Aluminum accumulation in tangle-bearing neurons of Alzheimer's disease with Balint's syndrome in a long-term aluminum refiner. Acta neuropathologica. vol 74. issue 1. 1987-10-27. PMID:3661119. |
neuropathological examination revealed characteristic features of alzheimer's disease with marked atrophy of the occipito-temporal lobes and senile plaques of the cerebellum. |
1987-10-27 |
2023-08-11 |
Not clear |
| D E Schmechel, P J Marangos, B M Martin, S Winfield, D S Burkhart, A D Roses, E I Ginn. Localization of neuron-specific enolase (NSE) mRNA in human brain. Neuroscience letters. vol 76. issue 2. 1987-07-14. PMID:3587757. |
in both aged controls and alzheimer's disease (ad) patients, nse probe hybridized with variable intensity to nerve cells in visual cortex and cerebellum, but not to glial or liver cells. |
1987-07-14 |
2023-08-11 |
human |
| B Horwitz, C L Grady, N L Schlageter, R Duara, S I Rapopor. Intercorrelations of regional cerebral glucose metabolic rates in Alzheimer's disease. Brain research. vol 407. issue 2. 1987-06-17. PMID:3494486. |
compared with healthy controls, the alzheimer patients had significantly fewer reliable partial correlation coefficients between frontal and parietal lobe regions, and more reliable correlations between the cerebellum and temporal lobe. |
1987-06-17 |
2023-08-11 |
Not clear |