| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Vikas Dhikav, Kuljeet Singh Anan. Are vascular factors linked to the development of hippocampal atrophy in Alzheimer's disease? Journal of Alzheimer's disease : JAD. vol 32. issue 3. 2013-09-04. PMID:22850312. |
are vascular factors linked to the development of hippocampal atrophy in alzheimer's disease? |
2013-09-04 |
2023-08-12 |
Not clear |
| Vikas Dhikav, Kuljeet Singh Anan. Are vascular factors linked to the development of hippocampal atrophy in Alzheimer's disease? Journal of Alzheimer's disease : JAD. vol 32. issue 3. 2013-09-04. PMID:22850312. |
recently, the role of vascular factors in alzheimer's disease in causing significant hippocampal damage has started emerging. |
2013-09-04 |
2023-08-12 |
Not clear |
| Shailesh N Mistry, Celine Valant, Patrick M Sexton, Ben Capuano, Arthur Christopoulos, Peter J Scammell. Synthesis and pharmacological profiling of analogues of benzyl quinolone carboxylic acid (BQCA) as allosteric modulators of the M1 muscarinic receptor. Journal of medicinal chemistry. vol 56. issue 12. 2013-09-03. PMID:23718562. |
established therapy in alzheimer's disease involves potentiation of the endogenous orthosteric ligand, acetylcholine, at the m1 muscarinic receptors found in higher concentrations in the cortex and hippocampus. |
2013-09-03 |
2023-08-12 |
Not clear |
| Ling-Feng Jiang, Hai-Lin Liao, Hong-Miao Huang, Li-Xia Zhou, Ling Li, Shi-Xian Cheng, Cheng-Zhi D. Potential prevention and treatment of maifanite for Alzheimer's disease based on behavior test, oxidative stress assay, and trace element analysis in hippocampus of Aβ(₂₅₋₃₅)-induced AD rats. Biological trace element research. vol 152. issue 1. 2013-08-29. PMID:23279943. |
potential prevention and treatment of maifanite for alzheimer's disease based on behavior test, oxidative stress assay, and trace element analysis in hippocampus of aβ(₂₅₋₃₅)-induced ad rats. |
2013-08-29 |
2023-08-12 |
rat |
| Seyed A Sajjadi, Julio Acosta-Cabronero, Karalyn Patterson, Lara Z Diaz-de-Grenu, Guy B Williams, Peter J Nesto. Diffusion tensor magnetic resonance imaging for single subject diagnosis in neurodegenerative diseases. Brain : a journal of neurology. vol 136. issue Pt 7. 2013-08-29. PMID:23729473. |
consistent with past reports for the respective clinical syndromes, these were centred on the left frontal operculum and caudate nucleus in non-fluent primary progressive aphasia (the corticobasal degeneration/progressive supranuclear palsy set), anterior temporal lobes in semantic dementia, and hippocampus and posterior cingulate gyrus in alzheimer's disease. |
2013-08-29 |
2023-08-12 |
human |
| Ruiqing Ni, Per-Göran Gillberg, Assar Bergfors, Amelia Marutle, Agneta Nordber. Amyloid tracers detect multiple binding sites in Alzheimer's disease brain tissue. Brain : a journal of neurology. vol 136. issue Pt 7. 2013-08-29. PMID:23757761. |
saturation binding studies revealed the presence of high- and low-affinity (3)h-pittsburgh compound b binding sites in the frontal cortex (k(d1): 3.5 ± 1.6 nm; k(d2): 133 ± 30 nm) and hippocampus (k(d1):5.6 ± 2.2 nm; k(d2): 181 ± 132 nm) of alzheimer's disease brains. |
2013-08-29 |
2023-08-12 |
human |
| Ruiqing Ni, Per-Göran Gillberg, Assar Bergfors, Amelia Marutle, Agneta Nordber. Amyloid tracers detect multiple binding sites in Alzheimer's disease brain tissue. Brain : a journal of neurology. vol 136. issue Pt 7. 2013-08-29. PMID:23757761. |
(3)h-pittsburgh compound b binding in alzheimer's disease brains was higher in the frontal and parietal cortices than in the caudate nucleus and hippocampus, and negligible in the cerebellum. |
2013-08-29 |
2023-08-12 |
human |
| Jorge Sepulcre, Mert R Sabuncu, Alex Becker, Reisa Sperling, Keith A Johnso. In vivo characterization of the early states of the amyloid-beta network. Brain : a journal of neurology. vol 136. issue Pt 7. 2013-08-29. PMID:23801740. |
moreover, the orbitofrontal cortex, amygdala nucleus and hippocampus exhibit hub properties in the amyloid-β network that may be critical to understanding the putative spreading mechanisms of alzheimer's disease pathology in early stages. |
2013-08-29 |
2023-08-12 |
human |
| Jing Xie, Owen Carmichae. Brain shape regression components. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference. vol 2012. 2013-08-26. PMID:23366477. |
when applied to hippocampi of 299 alzheimer's disease neuroimaging initiative (adni) participants, the method identified correlations between hippocampal atrophy and markers of ad pathology and cogniton that were stronger than, and covered a more extended spatial region than, those identified by competing approaches. |
2013-08-26 |
2023-08-12 |
human |
| David J Koss, Benjamin D Drever, Sandra Stoppelkamp, Gernot Riedel, Bettina Plat. Age-dependent changes in hippocampal synaptic transmission and plasticity in the PLB1Triple Alzheimer mouse. Cellular and molecular life sciences : CMLS. vol 70. issue 14. 2013-08-26. PMID:23407662. |
age-dependent changes in hippocampal synaptic transmission and plasticity in the plb1triple alzheimer mouse. |
2013-08-26 |
2023-08-12 |
mouse |
| Larry C Schmued, James Raymick, Merle G Paule, Melanie Dumas, Sumit Sarka. Characterization of myelin pathology in the hippocampal complex of a transgenic mouse model of Alzheimer's disease. Current Alzheimer research. vol 10. issue 1. 2013-08-21. PMID:23157338. |
characterization of myelin pathology in the hippocampal complex of a transgenic mouse model of alzheimer's disease. |
2013-08-21 |
2023-08-12 |
mouse |
| Larry C Schmued, James Raymick, Merle G Paule, Melanie Dumas, Sumit Sarka. Characterization of myelin pathology in the hippocampal complex of a transgenic mouse model of Alzheimer's disease. Current Alzheimer research. vol 10. issue 1. 2013-08-21. PMID:23157338. |
we have characterized the myelin changes observed within the hippocampal complex (hc) of a transgenic (tg) mouse model of alzheimer's disease (ad). |
2013-08-21 |
2023-08-12 |
mouse |
| Beatriz G Perez Nievas, Thea Hammerschmidt, Markus P Kummer, Dick Terwel, Juan C Leza, Michael T Henek. Restraint stress increases neuroinflammation independently of amyloid β levels in amyloid precursor protein/PS1 transgenic mice. Journal of neurochemistry. vol 116. issue 1. 2013-08-20. PMID:21044080. |
both hypercortisolemia and hippocampal damage are features found in patients diagnosed of alzheimer's disease (ad) and epidemiological evidence supports a role for stress as a risk factor for ad. |
2013-08-20 |
2023-08-12 |
mouse |
| Shashwath A Meda, Mary Ellen I Koran, Jennifer R Pryweller, Jennifer N Vega, Tricia A Thornton-Well. Genetic interactions associated with 12-month atrophy in hippocampus and entorhinal cortex in Alzheimer's Disease Neuroimaging Initiative. Neurobiology of aging. vol 34. issue 5. 2013-08-13. PMID:23107432. |
genetic interactions associated with 12-month atrophy in hippocampus and entorhinal cortex in alzheimer's disease neuroimaging initiative. |
2013-08-13 |
2023-08-12 |
Not clear |
| Huidong Tang, XiaoOu Mao, Lin Xie, David A Greenberg, Kunlin Ji. Expression level of vascular endothelial growth factor in hippocampus is associated with cognitive impairment in patients with Alzheimer's disease. Neurobiology of aging. vol 34. issue 5. 2013-08-13. PMID:23182805. |
expression level of vascular endothelial growth factor in hippocampus is associated with cognitive impairment in patients with alzheimer's disease. |
2013-08-13 |
2023-08-12 |
Not clear |
| Tania Araujo Viel, Ariadiny Lima Caetano, Marilia Silva Albuquerque, Mariana Silva Araujo, Hudson Sousa Buc. Chronic infusion of amyloid-β peptide and sustained attention altered α7 nicotinic receptor density in the rat brain. Current Alzheimer research. vol 9. issue 10. 2013-08-09. PMID:22515492. |
it is already known that progressive degeneration of cholinergic neurons in brain areas such as the hippocampus and the cortex leads to memory deficits, as observed in alzheimer's disease. |
2013-08-09 |
2023-08-12 |
mouse |
| Ghorbangol Ashabi, Shabnam Zeighamy Alamdary, Mahmoudreza Ramin, Fariba Khodaghol. Reduction of hippocampal apoptosis by intracerebroventricular administration of extracellular signal-regulated protein kinase and/or p38 inhibitors in amyloid beta rat model of Alzheimer's disease: involvement of nuclear-related factor-2 and nuclear factor-κB. Basic & clinical pharmacology & toxicology. vol 112. issue 3. 2013-08-05. PMID:22913737. |
reduction of hippocampal apoptosis by intracerebroventricular administration of extracellular signal-regulated protein kinase and/or p38 inhibitors in amyloid beta rat model of alzheimer's disease: involvement of nuclear-related factor-2 and nuclear factor-κb. |
2013-08-05 |
2023-08-12 |
rat |
| Ignatius A Tavares, Dona Touma, Steven Lynham, Claire Troakes, Megan Schober, Mirsada Causevic, Ritu Garg, Wendy Noble, Richard Killick, Istvan Bodi, Diane P Hanger, Jonathan D H Morri. Prostate-derived sterile 20-like kinases (PSKs/TAOKs) phosphorylate tau protein and are activated in tangle-bearing neurons in Alzheimer disease. The Journal of biological chemistry. vol 288. issue 21. 2013-08-05. PMID:23585562. |
psk catalytic activity is enhanced in the entorhinal cortex and hippocampus, areas of the brain that are most susceptible to alzheimer pathology, in comparison with the cerebellum, which is relatively spared. |
2013-08-05 |
2023-08-12 |
human |
| Nikki H Stricker, Hiroko H Dodge, N Maritza Dowling, S Duke Han, Elena A Erosheva, William J Jagus. CSF biomarker associations with change in hippocampal volume and precuneus thickness: implications for the Alzheimer's pathological cascade. Brain imaging and behavior. vol 6. issue 4. 2013-08-02. PMID:22614327. |
csf biomarker associations with change in hippocampal volume and precuneus thickness: implications for the alzheimer's pathological cascade. |
2013-08-02 |
2023-08-12 |
Not clear |
| Loukia Katsouri, Marcela P Vizcaychipi, Simon McArthur, Ian Harrison, Marc Suárez-Calvet, Alberto Lleo, Dafydd G Lloyd, Daqing Ma, Magdalena Sastr. Prazosin, an α(1)-adrenoceptor antagonist, prevents memory deterioration in the APP23 transgenic mouse model of Alzheimer's disease. Neurobiology of aging. vol 34. issue 4. 2013-08-01. PMID:23063647. |
noradrenergic deficits have been described in the hippocampus and the frontal cortex of alzheimer's disease brains, which are secondary to locus coeruleus degeneration. |
2013-08-01 |
2023-08-12 |
mouse |