| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ghorbangol Ashabi, Shabnam Zeighamy Alamdary, Mahmoudreza Ramin, Fariba Khodaghol. Reduction of hippocampal apoptosis by intracerebroventricular administration of extracellular signal-regulated protein kinase and/or p38 inhibitors in amyloid beta rat model of Alzheimer's disease: involvement of nuclear-related factor-2 and nuclear factor-κB. Basic & clinical pharmacology & toxicology. vol 112. issue 3. 2013-08-05. PMID:22913737. |
reduction of hippocampal apoptosis by intracerebroventricular administration of extracellular signal-regulated protein kinase and/or p38 inhibitors in amyloid beta rat model of alzheimer's disease: involvement of nuclear-related factor-2 and nuclear factor-κb. |
2013-08-05 |
2023-08-12 |
rat |
| Ignatius A Tavares, Dona Touma, Steven Lynham, Claire Troakes, Megan Schober, Mirsada Causevic, Ritu Garg, Wendy Noble, Richard Killick, Istvan Bodi, Diane P Hanger, Jonathan D H Morri. Prostate-derived sterile 20-like kinases (PSKs/TAOKs) phosphorylate tau protein and are activated in tangle-bearing neurons in Alzheimer disease. The Journal of biological chemistry. vol 288. issue 21. 2013-08-05. PMID:23585562. |
psk catalytic activity is enhanced in the entorhinal cortex and hippocampus, areas of the brain that are most susceptible to alzheimer pathology, in comparison with the cerebellum, which is relatively spared. |
2013-08-05 |
2023-08-12 |
human |
| Nikki H Stricker, Hiroko H Dodge, N Maritza Dowling, S Duke Han, Elena A Erosheva, William J Jagus. CSF biomarker associations with change in hippocampal volume and precuneus thickness: implications for the Alzheimer's pathological cascade. Brain imaging and behavior. vol 6. issue 4. 2013-08-02. PMID:22614327. |
csf biomarker associations with change in hippocampal volume and precuneus thickness: implications for the alzheimer's pathological cascade. |
2013-08-02 |
2023-08-12 |
Not clear |
| Loukia Katsouri, Marcela P Vizcaychipi, Simon McArthur, Ian Harrison, Marc Suárez-Calvet, Alberto Lleo, Dafydd G Lloyd, Daqing Ma, Magdalena Sastr. Prazosin, an α(1)-adrenoceptor antagonist, prevents memory deterioration in the APP23 transgenic mouse model of Alzheimer's disease. Neurobiology of aging. vol 34. issue 4. 2013-08-01. PMID:23063647. |
noradrenergic deficits have been described in the hippocampus and the frontal cortex of alzheimer's disease brains, which are secondary to locus coeruleus degeneration. |
2013-08-01 |
2023-08-12 |
mouse |
| Hannah Brautigam, John W Steele, David Westaway, Paul E Fraser, Peter H St George-Hyslop, Sam Gandy, Patrick R Hof, Dara L Dickstei. The isotropic fractionator provides evidence for differential loss of hippocampal neurons in two mouse models of Alzheimer's disease. Molecular neurodegeneration. vol 7. 2013-07-30. PMID:23173713. |
the isotropic fractionator provides evidence for differential loss of hippocampal neurons in two mouse models of alzheimer's disease. |
2013-07-30 |
2023-08-12 |
mouse |
| Junghoe Kim, Yong-Hwan Kim, Jong-Hwan Le. Hippocampus-precuneus functional connectivity as an early sign of Alzheimer's disease: a preliminary study using structural and functional magnetic resonance imaging data. Brain research. vol 1495. 2013-07-22. PMID:23247063. |
alzheimer's disease (ad) is characterized by structural atrophies in the hippocampus (hp) and aberrant patterns of functional connectivities (fc) between the hippocampus and the rest of the brain. |
2013-07-22 |
2023-08-12 |
Not clear |
| Chuang Guo, Pu Wang, Man-Li Zhong, Tao Wang, Xue-Shi Huang, Jia-Yi Li, Zhan-You Wan. Deferoxamine inhibits iron induced hippocampal tau phosphorylation in the Alzheimer transgenic mouse brain. Neurochemistry international. vol 62. issue 2. 2013-07-22. PMID:23262393. |
deferoxamine inhibits iron induced hippocampal tau phosphorylation in the alzheimer transgenic mouse brain. |
2013-07-22 |
2023-08-12 |
mouse |
| Francesca Fanelli, Sara Sepe, Marcello D'Amelio, Cinzia Bernardi, Loredana Cristiano, AnnaMaria Cimini, Francesco Cecconi, Maria Paola Ceru', Sandra Moren. Age-dependent roles of peroxisomes in the hippocampus of a transgenic mouse model of Alzheimer's disease. Molecular neurodegeneration. vol 8. 2013-07-22. PMID:23374228. |
age-dependent roles of peroxisomes in the hippocampus of a transgenic mouse model of alzheimer's disease. |
2013-07-22 |
2023-08-12 |
mouse |
| Francesca Fanelli, Sara Sepe, Marcello D'Amelio, Cinzia Bernardi, Loredana Cristiano, AnnaMaria Cimini, Francesco Cecconi, Maria Paola Ceru', Sandra Moren. Age-dependent roles of peroxisomes in the hippocampus of a transgenic mouse model of Alzheimer's disease. Molecular neurodegeneration. vol 8. 2013-07-22. PMID:23374228. |
alzheimer's disease (ad) is a progressive neurodegenerative disease, especially affecting the hippocampus. |
2013-07-22 |
2023-08-12 |
mouse |
| Bai Lu, Guhan Nagappan, Xiaoming Guan, Pradeep J Nathan, Paul Wre. BDNF-based synaptic repair as a disease-modifying strategy for neurodegenerative diseases. Nature reviews. Neuroscience. vol 14. issue 6. 2013-07-16. PMID:23674053. |
understanding the role of brain-derived neurotrophic factor (bdnf) in synaptic plasticity and synaptogenesis, the impact of the bdnf val66met polymorphism in alzheimer's disease-relevant endophenotypes - including episodic memory and hippocampal volume - and the technological progress in measuring synaptic changes in humans all pave the way for a 'synaptic repair' therapy for neurodegenerative diseases that targets pathophysiology rather than pathogenesis. |
2013-07-16 |
2023-08-12 |
Not clear |
| José Julio Rodríguez, Harun N Noristani, Alexei Verkhratsk. The serotonergic system in ageing and Alzheimer's disease. Progress in neurobiology. vol 99. issue 1. 2013-07-10. PMID:22766041. |
alzheimer's disease (ad) is one of the major neurodegenerative diseases that deteriorates cognitive functions and primarily affects associated brain regions involved in learning and memory, such as the neocortex and the hippocampus. |
2013-07-10 |
2023-08-12 |
Not clear |
| Jie Wu, Tingting Ding, Jiao Su. Neurotoxic potential of iron oxide nanoparticles in the rat brain striatum and hippocampus. Neurotoxicology. vol 34. 2013-07-09. PMID:22995439. |
the striatum and hippocampus are important structures in the brain and are associated with the development of parkinson's and alzheimer's diseases. |
2013-07-09 |
2023-08-12 |
rat |
| J A Maldjian, C T Whitlo. Whither the hippocampus? FDG-PET hippocampal hypometabolism in Alzheimer disease revisited. AJNR. American journal of neuroradiology. vol 33. issue 10. 2013-07-08. PMID:22700745. |
fdg-pet hippocampal hypometabolism in alzheimer disease revisited. |
2013-07-08 |
2023-08-12 |
human |
| Daan van Abel, Omar Michel, Rob Veerhuis, Marlies Jacobs, Marie van Dijk, Cees B M Oudejan. Direct downregulation of CNTNAP2 by STOX1A is associated with Alzheimer's disease. Journal of Alzheimer's disease : JAD. vol 31. issue 4. 2013-07-08. PMID:22728895. |
additionally, we show that cntnap2 expression is downregulated in the hippocampus of alzheimer's disease patients where stox1a expression has been shown to be upregulated. |
2013-07-08 |
2023-08-12 |
Not clear |
| Juan Sanchez-Ramos, Cynthia Cimino, Ross Avila, Amanda Rowe, Ren Chen, Glenn Whelan, Xiaoyang Lin, Chuanhai Cao, Raj Asho. Pilot study of granulocyte-colony stimulating factor for treatment of Alzheimer's disease. Journal of Alzheimer's disease : JAD. vol 31. issue 4. 2013-07-08. PMID:22751169. |
in pre-clinical studies, g-csf was reported to improve spatial learning performance and to markedly reduce amyloid deposition in hippocampus and entorhinal cortex in a murine model of alzheimer's disease (ad). |
2013-07-08 |
2023-08-12 |
human |
| Akari Ogawa, Yu Yamazaki, Masahiro Nakamori, Tetsuya Takahashi, Takashi Kurashige, Masanori Hiji, Yoshito Nagano, Takemori Yamawaki, Masayasu Matsumot. Characterization and distribution of adaptor protein containing a PH domain, PTB domain and leucine zipper motif (APPL1) in Alzheimer's disease hippocampus: an immunohistochemical study. Brain research. vol 1494. 2013-07-03. PMID:23246927. |
characterization and distribution of adaptor protein containing a ph domain, ptb domain and leucine zipper motif (appl1) in alzheimer's disease hippocampus: an immunohistochemical study. |
2013-07-03 |
2023-08-12 |
human |
| b' Jana Mrzilkov\\xc3\\xa1, Petr Zach, Ale\\xc5\\xa1 Barto\\xc5\\xa1, Ji\\xc5\\x99\\xc3\\xad Tint\\xc4\\x9bra, Daniela \\xc5\\x98\\xc3\\xadpov\\xc3\\xa. Volumetric analysis of the pons, cerebellum and hippocampi in patients with Alzheimer\'s disease. Dementia and geriatric cognitive disorders. vol 34. issue 3-4. 2013-07-02. PMID:23128238.' |
our goal was to find out whether a decrease in hippocampal volume in alzheimer's disease measured via magnetic resonance imaging is accompanied by a similar volume decrease in the pons and cerebellum. |
2013-07-02 |
2023-08-12 |
Not clear |
| Lan Zhang, Shun Yu, Ruyi Zhang, Ying Xing, Yaohua Li, Lin L. Tetrahydroxystilbene glucoside antagonizes age-related α-synuclein overexpression in the hippocampus of APP transgenic mouse model of Alzheimer's disease. Restorative neurology and neuroscience. vol 31. issue 1. 2013-06-28. PMID:23160059. |
tetrahydroxystilbene glucoside antagonizes age-related α-synuclein overexpression in the hippocampus of app transgenic mouse model of alzheimer's disease. |
2013-06-28 |
2023-08-12 |
mouse |
| Jian-Qiao Fang, Shu-Xiu Zhu, Ying Zhang, Fang Wang, Qing-Yan Zh. [Effect of electroacupuncture on expression of phosphorylated P 38 MAPK and IL-1beta in frontal lobe and hippocampus in rats with Alzheimer's disease]. Zhen ci yan jiu = Acupuncture research. vol 38. issue 1. 2013-06-28. PMID:23650798. |
[effect of electroacupuncture on expression of phosphorylated p 38 mapk and il-1beta in frontal lobe and hippocampus in rats with alzheimer's disease]. |
2013-06-28 |
2023-08-12 |
rat |
| Jian-Qiao Fang, Shu-Xiu Zhu, Ying Zhang, Fang Wang, Qing-Yan Zh. [Effect of electroacupuncture on expression of phosphorylated P 38 MAPK and IL-1beta in frontal lobe and hippocampus in rats with Alzheimer's disease]. Zhen ci yan jiu = Acupuncture research. vol 38. issue 1. 2013-06-28. PMID:23650798. |
to observe the effect of electroacupuncture (ea) intervention on expression of phosphorylated mitogen activated protein kinase-p 38 (p-p 38 mapk) protein and interleukin 1beta (il-1beta)mrna in the frontal lobe and hippocampus in alzheimer's disease (ad) rats so as to explore its mechanisms underlying improvement of ad in clinic. |
2013-06-28 |
2023-08-12 |
rat |