| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Doaa G Ali, Ahmed A Bahrani, Justin M Barber, Riham H El Khouli, Brian T Gold, Jordan P Harp, Yang Jiang, Donna M Wilcock, Gregory A Jich. Amyloid-PET Levels in the Precuneus and Posterior Cingulate Cortices Are Associated with Executive Function Scores in Preclinical Alzheimer's Disease Prior to Overt Global Amyloid Positivity. Journal of Alzheimer's disease : JAD. 2022-06-27. PMID:35754276. |
amyloid-pet levels in the precuneus and posterior cingulate cortices are associated with executive function scores in preclinical alzheimer's disease prior to overt global amyloid positivity. |
2022-06-27 |
2023-08-14 |
Not clear |
| Alberto Benussi, Valentina Cantoni, Mario Grassi, Lucie Brechet, Christoph M Michel, Abhishek Datta, Chris Thomas, Stefano Gazzina, Maria Sofia Cotelli, Marta Bianchi, Enrico Premi, Yasmine Gadola, Maria Cotelli, Marta Pengo, Federica Perrone, Maria Scolaro, Silvana Archetti, Eino Solje, Alessandro Padovani, Alvaro Pascual-Leone, Barbara Borron. Increasing brain gamma activity improves episodic memory and restores cholinergic dysfunction in Alzheimer's disease. Annals of neurology. 2022-05-24. PMID:35607946. |
to assess whether non-invasive brain stimulation with transcranial alternating current stimulation at gamma-frequency (γ-tacs) applied over the precuneus can improve episodic memory and modulate cholinergic transmission by modulating cerebral rhythms in early alzheimer's disease (ad). |
2022-05-24 |
2023-08-13 |
Not clear |
| Valeria Isella, Cinzia Crivellaro, Anna Formenti, Monica Musarra, Sara Pacella, Sabrina Morzenti, Francesca Ferri, Cristina Mapelli, Francesca Gallivanone, Luca Guerra, Ildebrando Appollonio, Carlo Ferrares. Validity of cingulate-precuneus-temporo-parietal hypometabolism for single-subject diagnosis of biomarker-proven atypical variants of Alzheimer's Disease. Journal of neurology. 2022-03-29. PMID:35347453. |
the aim of our study was to establish empirically to what extent reduced glucose uptake in the precuneus, posterior cingulate and/or temporo-parietal cortex (pctp), which is thought to indicate brain amyloidosis in patients with dementia or mci due to alzheimer's disease (ad), permits to distinguish amyloid-positive from amyloid-negative patients with non-classical ad phenotypes at the single-case level. |
2022-03-29 |
2023-08-13 |
Not clear |
| Qing Wang, Gengsheng Chen, Suzanne E Schindler, Jon Christensen, Nicole S McKay, Jingxia Liu, Sicheng Wang, Zhexian Sun, Jason Hassenstab, Yi Su, Shaney Flores, Russ Hornbeck, Lisa Cash, Carlos Cruchaga, Anne M Fagan, Zhude Tu, John C Morris, Mark A Mintun, Yong Wang, Tammie L S Benzinge. Baseline Microglial Activation Correlates With Brain Amyloidosis and Longitudinal Cognitive Decline in Alzheimer Disease. Neurology(R) neuroimmunology & neuroinflammation. vol 9. issue 3. 2022-03-09. PMID:35260470. |
this study aims to quantify microglial activation in individuals with alzheimer disease (ad) using the 18-kda translocator protein (tspo) pet imaging in the hippocampus and precuneus, the 2 ad-vulnerable regions, and to evaluate the association of baseline neuroinflammation with amyloidosis, tau, and longitudinal cognitive decline. |
2022-03-09 |
2023-08-13 |
Not clear |
| Christian Sandøe Musaeus, Louise Baruël Johansen, Steen Hasselbalch, Nina Beyer, Peter Høgh, Hartwig Roman Siebner, Kristian Steen Frederikse. Sixteen weeks of aerobic exercise does not alter resting-state connectivity of the precuneus in patients with Alzheimer's disease. Current Alzheimer research. 2022-03-07. PMID:35249488. |
sixteen weeks of aerobic exercise does not alter resting-state connectivity of the precuneus in patients with alzheimer's disease. |
2022-03-07 |
2023-08-13 |
Not clear |
| Alberto Benussi, Valentina Cantoni, Maria Sofia Cotelli, Maria Cotelli, Chiara Brattini, Abhishek Datta, Chris Thomas, Emiliano Santarnecchi, Alvaro Pascual-Leone, Barbara Borron. Exposure to gamma tACS in Alzheimer's disease: A randomized, double-blind, sham-controlled, crossover, pilot study. Brain stimulation. vol 14. issue 3. 2021-11-24. PMID:33762220. |
to assess whether exposure to non-invasive brain stimulation with transcranial alternating current stimulation at γ frequency (γ-tacs) applied over pz (an area overlying the medial parietal cortex and the precuneus) can improve memory and modulate cholinergic transmission in mild cognitive impairment due to alzheimer's disease (mci-ad). |
2021-11-24 |
2023-08-13 |
Not clear |
| Laura J Mahady, Bin He, Michael Malek-Ahmadi, Elliott J Mufso. Telomeric alterations in the default mode network during the progression of Alzheimer's disease: Selective vulnerability of the precuneus. Neuropathology and applied neurobiology. vol 47. issue 3. 2021-11-22. PMID:33107640. |
telomeric alterations in the default mode network during the progression of alzheimer's disease: selective vulnerability of the precuneus. |
2021-11-22 |
2023-08-13 |
Not clear |
| Bin He, Sylvia E Perez, Sang H Lee, Stephen D Ginsberg, Michael Malek-Ahmadi, Elliott J Mufso. Expression profiling of precuneus layer III cathepsin D-immunopositive pyramidal neurons in mild cognitive impairment and Alzheimer's disease: Evidence for neuronal signaling vulnerability. The Journal of comparative neurology. vol 528. issue 16. 2021-11-16. PMID:32323319. |
expression profiling of precuneus layer iii cathepsin d-immunopositive pyramidal neurons in mild cognitive impairment and alzheimer's disease: evidence for neuronal signaling vulnerability. |
2021-11-16 |
2023-08-13 |
Not clear |
| Bin He, Sylvia E Perez, Sang H Lee, Stephen D Ginsberg, Michael Malek-Ahmadi, Elliott J Mufso. Expression profiling of precuneus layer III cathepsin D-immunopositive pyramidal neurons in mild cognitive impairment and Alzheimer's disease: Evidence for neuronal signaling vulnerability. The Journal of comparative neurology. vol 528. issue 16. 2021-11-16. PMID:32323319. |
the precuneus (prec; brodmann area 7), a key hub within the default mode network (dmn) displays amyloid and tau-containing neurofibrillary tangle (nft) pathology during the onset of alzheimer's disease (ad). |
2021-11-16 |
2023-08-13 |
Not clear |
| Mark R Libowitz, Ke Wei, Thao Tran, Karen Chu, Kristina Moncrieffe, Michael G Harrington, Kevin Kin. Regional brain volumes relate to Alzheimer's disease cerebrospinal fluid biomarkers and neuropsychometry: A cross-sectional, observational study. PloS one. vol 16. issue 7. 2021-11-10. PMID:34292973. |
113 participants ranging from cognitively healthy to alzheimer's disease underwent mri exams to obtain measurements of hippocampus, prefrontal cortex, precuneus, parietal cortex, and occipital lobe volumes. |
2021-11-10 |
2023-08-13 |
human |
| Miao Zhang, Wanqing Sun, Ziyun Guan, Jialin Hu, Binyin Li, Guanyu Ye, Hongping Meng, Xinyun Huang, Xiaozhu Lin, Jin Wang, Jun Liu, Biao Li, Yaoyu Zhang, Yao L. Simultaneous PET/fMRI Detects Distinctive Alterations in Functional Connectivity and Glucose Metabolism of Precuneus Subregions in Alzheimer's Disease. Frontiers in aging neuroscience. vol 13. 2021-10-12. PMID:34630070. |
simultaneous pet/fmri detects distinctive alterations in functional connectivity and glucose metabolism of precuneus subregions in alzheimer's disease. |
2021-10-12 |
2023-08-13 |
human |
| Miao Zhang, Wanqing Sun, Ziyun Guan, Jialin Hu, Binyin Li, Guanyu Ye, Hongping Meng, Xinyun Huang, Xiaozhu Lin, Jin Wang, Jun Liu, Biao Li, Yaoyu Zhang, Yao L. Simultaneous PET/fMRI Detects Distinctive Alterations in Functional Connectivity and Glucose Metabolism of Precuneus Subregions in Alzheimer's Disease. Frontiers in aging neuroscience. vol 13. 2021-10-12. PMID:34630070. |
as a central hub in the interconnected brain network, the precuneus has been reported showing disrupted functional connectivity and hypometabolism in alzheimer's disease (ad). |
2021-10-12 |
2023-08-13 |
human |
| Silvia Ingala, Jori Tomassen, Lyduine E Collij, Naomi Prent, Dennis van 't Ent, Mara Ten Kate, Elles Konijnenberg, Maqsood Yaqub, Philip Scheltens, Eco J C de Geus, Charlotte E Teunissen, Betty Tijms, Alle Meije Wink, Frederik Barkhof, Bart N M van Berckel, Pieter Jelle Visser, Anouk den Brabe. Amyloid-driven disruption of default mode network connectivity in cognitively healthy individuals. Brain communications. vol 3. issue 4. 2021-10-08. PMID:34617016. |
cortical accumulation of amyloid beta is one of the first events of alzheimer's disease pathophysiology, and has been suggested to follow a consistent spatiotemporal ordering, starting in the posterior cingulate cortex, precuneus and medio-orbitofrontal cortex. |
2021-10-08 |
2023-08-13 |
human |
| Dawn C Matthews, Xiangling Mao, Kathleen Dowd, Diamanto Tsakanikas, Caroline S Jiang, Caroline Meuser, Randolph D Andrews, Ana S Lukic, Jihyun Lee, Nicholas Hampilos, Neeva Shafiian, Mary Sano, P David Mozley, Howard Fillit, Bruce S McEwen, Dikoma C Shungu, Ana C Pereir. Riluzole, a glutamate modulator, slows cerebral glucose metabolism decline in patients with Alzheimer's disease. Brain : a journal of neurology. 2021-09-24. PMID:34145880. |
measures of cerebral glucose metabolism, a well-established alzheimer's disease biomarker and predictor of disease progression, declined significantly less in several pre-specified regions of interest with the most robust effect in posterior cingulate, and effects in precuneus, lateral temporal, right hippocampus and frontal cortex in riluzole-treated subjects in comparison to placebo group. |
2021-09-24 |
2023-08-13 |
human |
| Hiroshi Hayashi, Ryota Kobayashi, Shinobu Kawakatsu, Makoto Ohba, Daichi Morioka, Koichi Otan. Comparison of the decreases in regional cerebral blood flow in the posterior cingulate cortex, precuneus, and parietal lobe between suspected non-Alzheimer's disease pathophysiology and Alzheimer's disease. Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society. vol 21. issue 5. 2021-09-06. PMID:34101304. |
comparison of the decreases in regional cerebral blood flow in the posterior cingulate cortex, precuneus, and parietal lobe between suspected non-alzheimer's disease pathophysiology and alzheimer's disease. |
2021-09-06 |
2023-08-13 |
Not clear |
| Alexandra G Mitchell, Robert D McIntosh, Stephanie Rossit, Michael Hornberger, Suvankar Pa. Assessment of visually guided reaching in prodromal Alzheimer's disease: a cross-sectional study protocol. BMJ open. vol 10. issue 6. 2021-02-15. PMID:32503870. |
recent evidence has implicated the precuneus of the medial parietal lobe as one of the first brain areas to show pathological changes in alzheimer's disease (ad). |
2021-02-15 |
2023-08-13 |
Not clear |
| Naiara Aguirre, Víctor Costumero, Lidón Marin-Marin, Joaquín Escudero, Vicente Belloch, María Antonia Parcet, César Ávil. Activity in Memory Brain Networks During Encoding Differentiates Mild Cognitive Impairment Converters from Non-Converters. Journal of Alzheimer's disease : JAD. vol 71. issue 3. 2020-11-05. PMID:31476154. |
alzheimer's disease (ad) has been associated with memory impairment due to alterations in the medial temporal lobe (mtl) and the precuneus. |
2020-11-05 |
2023-08-13 |
human |
| Bernadet L Klaassens, Joop M A van Gerven, Jeroen van der Grond, Frank de Vos, Christiane Möller, Serge A R B Rombout. Diminished Posterior Precuneus Connectivity with the Default Mode Network Differentiates Normal Aging from Alzheimer's Disease. Frontiers in aging neuroscience. vol 9. 2020-10-01. PMID:28469571. |
diminished posterior precuneus connectivity with the default mode network differentiates normal aging from alzheimer's disease. |
2020-10-01 |
2023-08-13 |
human |
| Hao Guo, Fan Zhang, Junjie Chen, Yong Xu, Jie Xian. Machine Learning Classification Combining Multiple Features of A Hyper-Network of fMRI Data in Alzheimer's Disease. Frontiers in neuroscience. vol 11. 2020-10-01. PMID:29209156. |
the abnormal brain regions included the bilateral precuneus, right parahippocampal gyrus\hippocampus, right posterior cingulate gyrus, and other regions that are known to be important in alzheimer's disease. |
2020-10-01 |
2023-08-13 |
human |
| Pukovisa Prawiroharjo, Ken-Ichiro Yamashita, Koji Yamashita, Osamu Togao, Akio Hiwatashi, Ryo Yamasaki, Jun-Ichi Kir. Disconnection of the right superior parietal lobule from the precuneus is associated with memory impairment in oldest-old Alzheimer's disease patients. Heliyon. vol 6. issue 7. 2020-09-28. PMID:32728647. |
disconnection of the right superior parietal lobule from the precuneus is associated with memory impairment in oldest-old alzheimer's disease patients. |
2020-09-28 |
2023-08-13 |
human |