| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Matthieu Bailly, Christophe Destrieux, Caroline Hommet, Karl Mondon, Jean-Philippe Cottier, Emilie Beaufils, Emilie Vierron, Johnny Vercouillie, Méziane Ibazizene, Thierry Voisin, Pierre Payoux, Louisa Barré, Vincent Camus, Denis Guilloteau, Maria-Joao Ribeir. Precuneus and Cingulate Cortex Atrophy and Hypometabolism in Patients with Alzheimer's Disease and Mild Cognitive Impairment: MRI and (18)F-FDG PET Quantitative Analysis Using FreeSurfer. BioMed research international. vol 2015. 2016-06-06. PMID:26346648. |
the objective of this study was to compare glucose metabolism and atrophy, in the precuneus and cingulate cortex, in patients with alzheimer's disease (ad) and mild cognitive impairment (mci), using freesurfer. |
2016-06-06 |
2023-08-13 |
Not clear |
| Naoto Oikawa, Teruhiko Matsubara, Ryoto Fukuda, Hanaki Yasumori, Hiroyuki Hatsuta, Shigeo Murayama, Toshinori Sato, Akemi Suzuki, Katsuhiko Yanagisaw. Imbalance in fatty-acid-chain length of gangliosides triggers Alzheimer amyloid deposition in the precuneus. PloS one. vol 10. issue 3. 2016-02-22. PMID:25798597. |
imbalance in fatty-acid-chain length of gangliosides triggers alzheimer amyloid deposition in the precuneus. |
2016-02-22 |
2023-08-13 |
Not clear |
| Sylvia E Perez, Bin He, Muhammad Nadeem, Joanne Wuu, Stephen W Scheff, Eric E Abrahamson, Milos D Ikonomovic, Elliott J Mufso. Resilience of precuneus neurotrophic signaling pathways despite amyloid pathology in prodromal Alzheimer's disease. Biological psychiatry. vol 77. issue 8. 2016-01-01. PMID:24529280. |
resilience of precuneus neurotrophic signaling pathways despite amyloid pathology in prodromal alzheimer's disease. |
2016-01-01 |
2023-08-12 |
Not clear |
| Sylvia E Perez, Bin He, Muhammad Nadeem, Joanne Wuu, Stephen W Scheff, Eric E Abrahamson, Milos D Ikonomovic, Elliott J Mufso. Resilience of precuneus neurotrophic signaling pathways despite amyloid pathology in prodromal Alzheimer's disease. Biological psychiatry. vol 77. issue 8. 2016-01-01. PMID:24529280. |
reduction of precuneus choline acetyltransferase activity co-occurs with greater beta-amyloid (aβ) in alzheimer's disease (ad). |
2016-01-01 |
2023-08-12 |
Not clear |
| K Ishi. PET approaches for diagnosis of dementia. AJNR. American journal of neuroradiology. vol 35. issue 11. 2015-12-09. PMID:23945233. |
for example, fdg-pet demonstrates hypometabolic regions in the posterior cingulate gyri, precuneus, and parietotemporal association cortices, while amyloid pet indicates amyloid deposition in alzheimer disease and mild cognitive impairment due to alzheimer disease. |
2015-12-09 |
2023-08-12 |
Not clear |
| Chera L Maarouf, Tyler A Kokjohn, Douglas G Walker, Charisse M Whiteside, Walter M Kalback, Alexis Whetzel, Lucia I Sue, Geidy Serrano, Sandra A Jacobson, Marwan N Sabbagh, Eric M Reiman, Thomas G Beach, Alex E Rohe. Biochemical assessment of precuneus and posterior cingulate gyrus in the context of brain aging and Alzheimer's disease. PloS one. vol 9. issue 8. 2015-10-05. PMID:25166759. |
biochemical assessment of precuneus and posterior cingulate gyrus in the context of brain aging and alzheimer's disease. |
2015-10-05 |
2023-08-13 |
human |
| Chera L Maarouf, Tyler A Kokjohn, Douglas G Walker, Charisse M Whiteside, Walter M Kalback, Alexis Whetzel, Lucia I Sue, Geidy Serrano, Sandra A Jacobson, Marwan N Sabbagh, Eric M Reiman, Thomas G Beach, Alex E Rohe. Biochemical assessment of precuneus and posterior cingulate gyrus in the context of brain aging and Alzheimer's disease. PloS one. vol 9. issue 8. 2015-10-05. PMID:25166759. |
using elisa and western blotting methods, we quantified and compared the levels of several key molecules associated with neurodegenerative disease in the precuneus and posterior cingulate gyrus, two brain regions known to exhibit early imaging alterations during the course of alzheimer's disease. |
2015-10-05 |
2023-08-13 |
human |
| Shobana Sekar, Jacquelyn McDonald, Lori Cuyugan, Jessica Aldrich, Ahmet Kurdoglu, Jonathan Adkins, Geidy Serrano, Thomas G Beach, David W Craig, Jonathan Valla, Eric M Reiman, Winnie S Lian. Alzheimer's disease is associated with altered expression of genes involved in immune response and mitochondrial processes in astrocytes. Neurobiology of aging. vol 36. issue 2. 2015-09-28. PMID:25448601. |
alzheimer's disease (ad) is characterized by deficits in cerebral metabolic rates of glucose in the posterior cingulate (pc) and precuneus in ad subjects, and in apoeε4 carriers, decades before the onset of measureable cognitive deficits. |
2015-09-28 |
2023-08-13 |
human |
| Masoud Tahmasian, Lorenzo Pasquini, Martin Scherr, Chun Meng, Stefan Förster, Satja Mulej Bratec, Kuangyu Shi, Igor Yakushev, Markus Schwaiger, Timo Grimmer, Janine Diehl-Schmid, Valentin Riedl, Christian Sorg, Alexander Drzezg. The lower hippocampus global connectivity, the higher its local metabolism in Alzheimer disease. Neurology. vol 84. issue 19. 2015-07-23. PMID:25878180. |
based on the hippocampus disconnection hypothesis in alzheimer disease (ad), which postulates that uncoupling from cortical inputs contributes to disinhibition-like changes in hippocampus activity, we suggested that in patients with ad, the more the intrinsic functional connectivity between hippocampus and precuneus is decreased, the higher hippocampal glucose metabolism will be. |
2015-07-23 |
2023-08-13 |
Not clear |
| Kenji Ishibashi, Yoshiharu Miura, Keiichi Oda, Kiichi Ishiwata, Kenji Ishi. Alzheimer's disease-like pattern of (18)F-FDG uptake during a hyperglycemic state and negative (11)C-PiB binding in a patient with mild cognitive impairment. Journal of Alzheimer's disease : JAD. vol 42. issue 2. 2015-07-20. PMID:24898648. |
increased plasma glucose levels can cause the regional reduction of fluorine-18-labeled fluorodeoxyglucose (18f-fdg) uptake in the posterior cingulate, precuneus, and/or temporoparietal cortices as an alzheimer's disease (ad)-like pattern. |
2015-07-20 |
2023-08-13 |
Not clear |
| Marcio L F Balthazar, Fabrício R S Pereira, Tátila M Lopes, Elvis L da Silva, Ana Carolina Coan, Brunno M Campos, Niall W Duncan, Florindo Stella, Georg Northoff, Benito P Damasceno, Fernando Cende. Neuropsychiatric symptoms in Alzheimer's disease are related to functional connectivity alterations in the salience network. Human brain mapping. vol 35. issue 4. 2014-11-25. PMID:23418130. |
alzheimer's patients showed increased functional connectivity within the sn compared with controls (right anterior cingulate cortex and left medial frontal gyrus), along with reduced functional connectivity in the default-mode network (bilateral precuneus). |
2014-11-25 |
2023-08-12 |
human |
| Ludovico Minati, Dennis Chan, Chiara Mastropasqua, Laura Serra, Barbara Spanò, Camillo Marra, Carlo Caltagirone, Mara Cercignani, Marco Bozzal. Widespread alterations in functional brain network architecture in amnestic mild cognitive impairment. Journal of Alzheimer's disease : JAD. vol 40. issue 1. 2014-10-30. PMID:24366921. |
widespread disconnection was observed primarily in cortical hubs known to manifest early alzheimer's disease pathology, namely precuneus, parietal lobules, supramarginal and angular gyri, and cuneus, with additional involvement of subcortical regions, sensorimotor cortex and insula. |
2014-10-30 |
2023-08-12 |
Not clear |
| Mingrui Xia, Zhiqun Wang, Zhengjia Dai, Xia Liang, Haiqing Song, Ni Shu, Kuncheng Li, Yong H. Differentially disrupted functional connectivity in posteromedial cortical subregions in Alzheimer's disease. Journal of Alzheimer's disease : JAD. vol 39. issue 3. 2014-10-06. PMID:24217277. |
neuroimaging studies have demonstrated that patients with alzheimer's disease (ad) have remarkable focal grey matter loss and hypometabolism in the posteromedial cortex (pmc), which is composed of the precuneus and posterior cingulate cortex, suggesting an important association of the pmc with ad pathophysiology. |
2014-10-06 |
2023-08-12 |
human |
| Stephen W Scheff, Douglas A Price, Frederick A Schmitt, Kelly N Roberts, Milos D Ikonomovic, Elliott J Mufso. Synapse stability in the precuneus early in the progression of Alzheimer's disease. Journal of Alzheimer's disease : JAD. vol 35. issue 3. 2013-10-17. PMID:23478309. |
synapse stability in the precuneus early in the progression of alzheimer's disease. |
2013-10-17 |
2023-08-12 |
human |
| Nikki H Stricker, Hiroko H Dodge, N Maritza Dowling, S Duke Han, Elena A Erosheva, William J Jagus. CSF biomarker associations with change in hippocampal volume and precuneus thickness: implications for the Alzheimer's pathological cascade. Brain imaging and behavior. vol 6. issue 4. 2013-08-02. PMID:22614327. |
csf biomarker associations with change in hippocampal volume and precuneus thickness: implications for the alzheimer's pathological cascade. |
2013-08-02 |
2023-08-12 |
Not clear |
| Lorena Rami, Roser Sala-Llonch, Cristina Solé-Padullés, Juan Fortea, Jaume Olives, Albert Lladó, Cleofe Peña-Gómez, Mircea Balasa, Bea Bosch, Anna Antonell, Raquel Sanchez-Valle, David Bartrés-Faz, Jose L Molinuev. Distinct functional activity of the precuneus and posterior cingulate cortex during encoding in the preclinical stage of Alzheimer's disease. Journal of Alzheimer's disease : JAD. vol 31. issue 3. 2013-05-21. PMID:22596271. |
distinct functional activity of the precuneus and posterior cingulate cortex during encoding in the preclinical stage of alzheimer's disease. |
2013-05-21 |
2023-08-12 |
human |
| M D Ikonomovic, W E Klunk, E E Abrahamson, J Wuu, C A Mathis, S W Scheff, E J Mufson, S T DeKosk. Precuneus amyloid burden is associated with reduced cholinergic activity in Alzheimer disease. Neurology. vol 77. issue 1. 2011-09-02. PMID:21700583. |
precuneus amyloid burden is associated with reduced cholinergic activity in alzheimer disease. |
2011-09-02 |
2023-08-12 |
Not clear |
| M D Ikonomovic, W E Klunk, E E Abrahamson, J Wuu, C A Mathis, S W Scheff, E J Mufson, S T DeKosk. Precuneus amyloid burden is associated with reduced cholinergic activity in Alzheimer disease. Neurology. vol 77. issue 1. 2011-09-02. PMID:21700583. |
this study examined the relationship between postmortem precuneus cholinergic enzyme activity, pittsburgh compound b (pib) binding, and soluble amyloid-β concentration in mild cognitive impairment (mci) and alzheimer disease (ad). |
2011-09-02 |
2023-08-12 |
Not clear |
| Lars Frings, Katharina Dressel, Stefanie Abel, Dorothee Saur, Dorothee Kümmerer, Irina Mader, Cornelius Weiller, Michael Hül. Reduced precuneus deactivation during object naming in patients with mild cognitive impairment, Alzheimer's disease, and frontotemporal lobar degeneration. Dementia and geriatric cognitive disorders. vol 30. issue 4. 2011-02-23. PMID:20938177. |
reduced precuneus deactivation during object naming in patients with mild cognitive impairment, alzheimer's disease, and frontotemporal lobar degeneration. |
2011-02-23 |
2023-08-12 |
human |
| Olga Meulenbroek, Mark Rijpkema, Roy P C Kessels, Marcel G M Olde Rikkert, Guillén Fernánde. Autobiographical memory retrieval in patients with Alzheimer's disease. NeuroImage. vol 53. issue 1. 2011-01-04. PMID:20570740. |
when compared to controls, alzheimer's patients showed enhanced activity in the left inferior frontal gyrus (lifg), ventromedial prefrontal cortex (vmpfc), right precuneus and left lingual gyrus. |
2011-01-04 |
2023-08-12 |
Not clear |