| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hiroshi Matsud. [Neuroimaging for patients with Alzheimer disease in routine practice]. Brain and nerve = Shinkei kenkyu no shinpo. vol 62. issue 7. 2010-10-07. PMID:20675879. |
perfusion reduction in the the posterior cingulate gyrus precuneus and in the parietal cortex was more prominent in the case of patients with early-onset alzheimer disease than in the case of patients with late-onset alzheimer disease. |
2010-10-07 |
2023-08-12 |
Not clear |
| Matthias L Schroeter, Timo Stein, Nina Maslowski, Jane Neuman. Neural correlates of Alzheimer's disease and mild cognitive impairment: a systematic and quantitative meta-analysis involving 1351 patients. NeuroImage. vol 47. issue 4. 2009-10-15. PMID:19463961. |
the meta-analysis reveals that early alzheimer's disease affects structurally the (trans-)entorhinal and hippocampal regions, functionally the inferior parietal lobules and precuneus. |
2009-10-15 |
2023-08-12 |
human |
| Matthias L Schroeter, Timo Stein, Nina Maslowski, Jane Neuman. Neural correlates of Alzheimer's disease and mild cognitive impairment: a systematic and quantitative meta-analysis involving 1351 patients. NeuroImage. vol 47. issue 4. 2009-10-15. PMID:19463961. |
results further may suggest that atrophy in the (trans-)entorhinal area/hippocampus and hypometabolism/hypoperfusion in the inferior parietal lobules predicts most reliably the progression from amnestic mild cognitive impairment to alzheimer's disease, whereas changes in the posterior cingulate cortex and precuneus are unspecific. |
2009-10-15 |
2023-08-12 |
human |
| Peter T Nelson, Erin L Abner, Stephen W Scheff, Frederick A Schmitt, Richard J Kryscio, Gregory A Jicha, Charles D Smith, Ela Patel, William R Markesber. Alzheimer's-type neuropathology in the precuneus is not increased relative to other areas of neocortex across a range of cognitive impairment. Neuroscience letters. vol 450. issue 3. 2009-04-20. PMID:19010392. |
we studied alzheimer's disease (ad) pathology in the precuneus and surrounding brain areas. |
2009-04-20 |
2023-08-12 |
human |
| Gwenn S Smith, Elisse Kramer, Yilong Ma, Carol R Hermann, Vijay Dhawan, Thomas Chaly, David Eidelber. Cholinergic modulation of the cerebral metabolic response to citalopram in Alzheimer's disease. Brain : a journal of neurology. vol 132. issue Pt 2. 2009-03-10. PMID:19153152. |
at baseline, cerebral glucose metabolism was reduced in alzheimer's disease patients relative to controls in right middle temporal, left posterior cingulate and parietal cortices (precuneus and inferior parietal lobule), as expected. |
2009-03-10 |
2023-08-12 |
human |
| K Herholz, S F Carter, M Jone. Positron emission tomography imaging in dementia. The British journal of radiology. vol 80 Spec No 2. 2008-05-15. PMID:18445746. |
when measuring rcmr(glc) in alzheimer's disease (ad), characteristic reductions in rcmr(glc) are found in neocortical association areas including the posterior cingulate, precuneus, temporoparietal and frontal multimodal association regions; the primary visual cortex, sensorimotor cortex, basal ganglia and cerebellum are relatively unaffected. |
2008-05-15 |
2023-08-12 |
Not clear |
| Giorgos Karas, Philip Scheltens, Serge Rombouts, Ronald van Schijndel, Martin Klein, Bethany Jones, Wiesje van der Flier, Hugo Vrenken, Frederik Barkho. Precuneus atrophy in early-onset Alzheimer's disease: a morphometric structural MRI study. Neuroradiology. vol 49. issue 12. 2008-04-25. PMID:17955233. |
precuneus atrophy in early-onset alzheimer's disease: a morphometric structural mri study. |
2008-04-25 |
2023-08-12 |
Not clear |
| Andrea E Cavann. The precuneus and consciousness. CNS spectrums. vol 12. issue 7. 2007-10-01. PMID:17603406. |
the precuneus, along with adjacent areas within the posteromedial parietal cortex, is among the most active cortical regions according to the "default mode" of brain function during the conscious resting state, whereas it selectively deactivates in a number of pathophysiological conditions (ie, sleep, vegetative state, drug-induced anesthesia), and neuropsychiatric disorders (ie, epilepsy, alzheimer's disease, and schizophrenia) characterized by impaired consciousness. |
2007-10-01 |
2023-08-12 |
Not clear |
| Sang Won Seo, Kiho Im, Jong-Min Lee, Yun-Hee Kim, Sung Tae Kim, Seong Yoon Kim, Dong Won Yang, Sun I Kim, Yoon Sun Cho, Duk L N. Cortical thickness in single- versus multiple-domain amnestic mild cognitive impairment. NeuroImage. vol 36. issue 2. 2007-07-18. PMID:17459730. |
our studies suggest that m-amci is a transitional state between s-amci and alzheimer's disease, and that the cortical thinning is evidence that the precuneus is responsible for the multiple cognitive impairments in m-amci. |
2007-07-18 |
2023-08-12 |
human |
| Hidenao Fukuyam. [Neuroimaging in mild cognitive impairment]. Rinsho shinkeigaku = Clinical neurology. vol 46. issue 11. 2007-06-11. PMID:17432181. |
s. minoshima reported the hypometabolism in the early stage of alzheimer's disease in the posterior cingulate gyrus or precuneus, but it has been still unknown why these areas showed hypoperfusion or hypometabolism in early phase of alzheimer's disease. |
2007-06-11 |
2023-08-12 |
human |
| An-Tao Du, Norbert Schuff, Joel H Kramer, Howard J Rosen, Maria Luisa Gorno-Tempini, Katherine Rankin, Bruce L Miller, Michael W Weine. Different regional patterns of cortical thinning in Alzheimer's disease and frontotemporal dementia. Brain : a journal of neurology. vol 130. issue Pt 4. 2007-05-30. PMID:17353226. |
compared to ftd patients, alzheimer's disease patients had a thinner cortex (p < 0.001) in parts of bilateral parietal and precuneus regions. |
2007-05-30 |
2023-08-12 |
human |
| Hiroshi Matsuda, Sunao Mizumura, Takehiko Nagao, Tsuneyoshi Ota, Tomomichi Iizuka, Kiyotaka Nemoto, Michihiro Kimura, Amane Tateno, Akiko Ishiwata, Ichiei Kuji, Heii Arai, Akira Homm. An easy Z-score imaging system for discrimination between very early Alzheimer's disease and controls using brain perfusion SPECT in a multicentre study. Nuclear medicine communications. vol 28. issue 3. 2007-04-02. PMID:17264779. |
in alzheimer's disease (ad), regional cerebral blood flow (rcbf) in the posterior cingulate gyrus and precuneus has been reported to decrease even at a very early stage. |
2007-04-02 |
2023-08-12 |
human |
| Paul M Kemp, Sandra A Hoffmann, Clive Holmes, Livia Bolt, Tony Ward, Robin B Holmes, John S Flemin. The contribution of statistical parametric mapping in the assessment of precuneal and medial temporal lobe perfusion by 99mTc-HMPAO SPECT in mild Alzheimer's and Lewy body dementia. Nuclear medicine communications. vol 26. issue 12. 2006-04-10. PMID:16264357. |
to assess the role of 99mtc-hexamethylpropyleneamine oxime single-photon emission computed tomography (99mtc-hmpao spect) imaging of the precuneus and medial temporal lobe in the individual patient with mild alzheimer's disease and dementia with lewy bodies (dlb) using statistical parametric mapping and visual image interpretation. |
2006-04-10 |
2023-08-12 |
Not clear |
| Eric M Reiman, Kewei Chen, Gene E Alexander, Richard J Caselli, Daniel Bandy, David Osborne, Ann M Saunders, John Hard. Correlations between apolipoprotein E epsilon4 gene dose and brain-imaging measurements of regional hypometabolism. Proceedings of the National Academy of Sciences of the United States of America. vol 102. issue 23. 2005-07-27. PMID:15932949. |
patients with alzheimer's disease (ad) have abnormally low positron emission tomography (pet) measurements of the cerebral metabolic rate for glucose (cmrgl) in regions of the precuneus and the posterior cingulate, parietotemporal, and frontal cortex. |
2005-07-27 |
2023-08-12 |
human |
| Kazunari Ishi. Clinical application of positron emission tomography for diagnosis of dementia. Annals of nuclear medicine. vol 16. issue 8. 2003-08-05. PMID:12593416. |
at the mild and moderate stages of alzheimer's disease (ad), glucose metabolism is reduced not only in the parietotemporal region but also in the posterior cingulate and precuneus. |
2003-08-05 |
2023-08-12 |
Not clear |
| Noriaki Hattori, Kazuo Abe, Saburo Sakoda, Tohru Sawad. Proton MR spectroscopic study at 3 Tesla on glutamate/glutamine in Alzheimer's disease. Neuroreport. vol 13. issue 1. 2002-07-18. PMID:11924885. |
to investigate metabolic changes in alzheimer's disease (ad), we performed proton mr spectroscopy at 3t spectra were acquired from the gray matter of the posterior cingulate gyrus and the precuneus, and from the parietooccipital white matter in nine ad patients and 12 controls. |
2002-07-18 |
2023-08-12 |
Not clear |
| E Salmon, F Collette, C Degueldre, C Lemaire, G Franc. Voxel-based analysis of confounding effects of age and dementia severity on cerebral metabolism in Alzheimer's disease. Human brain mapping. vol 10. issue 1. 2000-09-14. PMID:10843517. |
posterior cingulate and precuneus metabolism, assessed by positron emission tomography, was significantly correlated with age in a population of 46 patients with probable alzheimer's disease. |
2000-09-14 |
2023-08-12 |
Not clear |
| E Salmon, F Collette, C Degueldre, C Lemaire, G Franc. Voxel-based analysis of confounding effects of age and dementia severity on cerebral metabolism in Alzheimer's disease. Human brain mapping. vol 10. issue 1. 2000-09-14. PMID:10843517. |
metabolism in posterior cingulate and precuneus was higher in elderly than in younger patients with a diagnosis of alzheimer's disease, even when dementia severity was taken as a confounding covariate. |
2000-09-14 |
2023-08-12 |
Not clear |