| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Marc Guitart-Masip, Amy Walsh, Peter Dayan, Andreas Olsso. Anxiety associated with perceived uncontrollable stress enhances expectations of environmental volatility and impairs reward learning. Scientific reports. vol 13. issue 1. 2023-10-30. PMID:37891204. |
our findings show that following uncontrollable stress, anxiety promotes an overly volatile representation of the reward-structure of uncertain environments, impairing reward attainment, which is a potential path to anhedonia in depression. |
2023-10-30 |
2023-11-08 |
human |
| Yue Ma, Chunlei Guo, Yi Luo, Shanshan Gao, Jifei Sun, Qingyan Chen, Xueyu Lv, Jiudong Cao, Zhang Lei, Jiliang Fan. Altered neural activity in the reward-related circuit associated with anhedonia in mild to moderate Major Depressive Disorder. Journal of affective disorders. 2023-10-22. PMID:37866737. |
anhedonia is a significant predictor of disease progression and treatment outcomes in major depressive disorder (mdd), linked to reward network dysfunctions. |
2023-10-22 |
2023-11-08 |
Not clear |
| Diego Pizzagalli, Alexis Whitton, Michael Treadway, Ashleigh Rutherford, Poornima Kumar, Manon Ironside, Roselinde Kaiser, Boyu Ren, Rotem Da. Brain-based graph-theoretical predictive modeling to map the trajectory of transdiagnostic symptoms of anhedonia, impulsivity, and hypomania from the human functional connectome. Research square. 2023-10-16. PMID:37841877. |
taken together, across dsm mood diagnoses, efficiency and centrality of the reward circuit predicted symptoms of anhedonia, impulsivity, and (hypo)mania, cross-sectionally and prospectively. |
2023-10-16 |
2023-11-08 |
human |
| Hao Guo, Jintao Guo, Zihang Gao, Fei Luo, Enming Zhan. The role of amygdala-ventral pallidum pathway in depression-like behaviors in male mice. Journal of neuroscience research. 2023-10-10. PMID:37814992. |
depressive symptoms, such as anhedonia are largely caused by dysfunction in the brain's reward system, in which the ventral pallidum (vp) participates in by controlling dopamine release. |
2023-10-10 |
2023-10-15 |
mouse |
| Yaru Guo, Xinyu Huang, Ziying Li, Wenjun Li, Bing Shi, Yanan Cui, Chunyan Zhu, Lei Zhang, Anzhen Wang, Kai Wang, Fengqiong Y. Aberrant reward dynamics in depression with anticipatory anhedonia. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology. vol 154. 2023-08-04. PMID:37541075. |
aberrant reward dynamics in depression with anticipatory anhedonia. |
2023-08-04 |
2023-08-14 |
Not clear |
| Yaru Guo, Xinyu Huang, Ziying Li, Wenjun Li, Bing Shi, Yanan Cui, Chunyan Zhu, Lei Zhang, Anzhen Wang, Kai Wang, Fengqiong Y. Aberrant reward dynamics in depression with anticipatory anhedonia. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology. vol 154. 2023-08-04. PMID:37541075. |
previous studies have shown that anticipatory anhedonia is linked to abnormal reward processing. |
2023-08-04 |
2023-08-14 |
Not clear |
| Yaru Guo, Xinyu Huang, Ziying Li, Wenjun Li, Bing Shi, Yanan Cui, Chunyan Zhu, Lei Zhang, Anzhen Wang, Kai Wang, Fengqiong Y. Aberrant reward dynamics in depression with anticipatory anhedonia. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology. vol 154. 2023-08-04. PMID:37541075. |
the present study aimed to explore the underlying neural mechanism of the influence of anticipatory anhedonia symptoms on reward processing. |
2023-08-04 |
2023-08-14 |
Not clear |
| Ermis Ryakiotakis, Dimitra Fousfouka, Antonios Stamataki. Maternal neglect alters reward-anticipatory behavior, social status stability, and reward circuit activation in adult male rats. Frontiers in neuroscience. vol 17. 2023-07-31. PMID:37521688. |
previous studies demonstrate that rats undergoing denial of expected reward in the form of maternal contact (der-animal model of maternal neglect) during early post-natal life developed anhedonia, aggressive play-fight behaviors and aberrant prefrontal cortex structure and neurochemistry. |
2023-07-31 |
2023-08-14 |
rat |
| Jennifer N Bress, Elizabeth Arslanoglou, Samprit Banerjee, George S Alexopoulos, Dimitris N Kiosse. Positive Valence System Function and Anhedonia in Middle-Aged and Older Adults at High Suicide Risk. Biological psychology. 2023-07-27. PMID:37499781. |
the reward positivity (rewp) is an event-related potential measure of positive valence system function that relates to depression and anhedonia in children and young adults. |
2023-07-27 |
2023-08-14 |
Not clear |
| Alessandro Serrett. Anhedonia and Depressive Disorders. Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology. vol 21. issue 3. 2023-07-10. PMID:37424409. |
anhedonia has however expanded from its original definition to encompass a spectrum of reward processing deficits that received much interest in the last decades. |
2023-07-10 |
2023-08-14 |
human |
| Chloe C Boyle, Julienne E Bower, Naomi I Eisenberger, Michael R Irwi. Stress to Inflammation and Anhedonia: Mechanistic Insights from Preclinical and Clinical Models. Neuroscience and biobehavioral reviews. 2023-07-07. PMID:37419230. |
anhedonia, as evidenced by impaired pleasurable response to reward, reduced reward motivation, and/or deficits in reward-related learning, is a common feature of depression. |
2023-07-07 |
2023-08-14 |
Not clear |
| Alexis E Whitton, Poornima Kumar, Michael T Treadway, Ashleigh V Rutherford, Manon L Ironside, Dan Foti, Garrett Fitzmaurice, Fei Du, Diego A Pizzagall. Distinct profiles of anhedonia and reward processing and their prospective associations with quality of life among individuals with mood disorders. Molecular psychiatry. 2023-07-04. PMID:37402852. |
distinct profiles of anhedonia and reward processing and their prospective associations with quality of life among individuals with mood disorders. |
2023-07-04 |
2023-08-14 |
human |
| Alexis E Whitton, Poornima Kumar, Michael T Treadway, Ashleigh V Rutherford, Manon L Ironside, Dan Foti, Garrett Fitzmaurice, Fei Du, Diego A Pizzagall. Distinct profiles of anhedonia and reward processing and their prospective associations with quality of life among individuals with mood disorders. Molecular psychiatry. 2023-07-04. PMID:37402852. |
we assessed anhedonia severity along with two electroencephalographic markers of neural reward responsiveness (scalp-level 'reward positivity' amplitude and source-localized reward-related activation in the dorsal anterior cingulate cortex), and assessed quality of life at baseline, 3- and 6-month follow-up. |
2023-07-04 |
2023-08-14 |
human |
| Alexis E Whitton, Poornima Kumar, Michael T Treadway, Ashleigh V Rutherford, Manon L Ironside, Dan Foti, Garrett Fitzmaurice, Fei Du, Diego A Pizzagall. Distinct profiles of anhedonia and reward processing and their prospective associations with quality of life among individuals with mood disorders. Molecular psychiatry. 2023-07-04. PMID:37402852. |
furthermore, increased neural reward responsiveness at baseline was associated with greater improvements in quality of life over time, and this improvement was mediated by longitudinal improvements in anhedonia severity. |
2023-07-04 |
2023-08-14 |
human |
| Alexis E Whitton, Poornima Kumar, Michael T Treadway, Ashleigh V Rutherford, Manon L Ironside, Dan Foti, Garrett Fitzmaurice, Fei Du, Diego A Pizzagall. Distinct profiles of anhedonia and reward processing and their prospective associations with quality of life among individuals with mood disorders. Molecular psychiatry. 2023-07-04. PMID:37402852. |
treatments capable of improving anhedonia and normalizing brain reward function may be necessary for improving broader health outcomes for individuals seeking treatment for depression.clinicaltrials.gov identifier: nct01976975. |
2023-07-04 |
2023-08-14 |
human |
| J S T Ngan, W C Chan, S T Wong, C S M Wong, C P W Chen. Reward System in Late-Life Depression: a Cross-Sectional Case-Control Study. East Asian archives of psychiatry : official journal of the Hong Kong College of Psychiatrists = Dong Ya jing shen ke xue zhi : Xianggang jing shen ke yi xue yuan qi kan. vol 33. issue 2. 2023-07-03. PMID:37400229. |
deficits in reward processing are hypothesised to be associated with anhedonia. |
2023-07-03 |
2023-08-14 |
Not clear |
| Roslyn Harold, Kayla Donaldson, David Rollock, Roman Kotov, Greg Perlman, Dan Fot. Abnormal neurophysiological sensitivity to rewards in depression is moderated by sex and age in middle adulthood. Biological psychology. 2023-06-30. PMID:37390960. |
a candidate pathophysiological process in major depressive disorder is diminished neural reactivity to reward delivery, which is theorized to give rise to anhedonia. |
2023-06-30 |
2023-08-14 |
Not clear |
| Mauro Scala, Giuseppe Fanelli, Diana De Ronchi, Alessandro Serretti, Chiara Fabbr. Clinical specificity profile for novel rapid acting antidepressant drugs. International clinical psychopharmacology. 2023-06-29. PMID:37381161. |
these new drugs were developed with the aim of combining a rapid action, a tolerable profile, and higher effectiveness on specific symptoms, which were relatively poorly targeted by standard antidepressants, such as anhedonia and response to reward, suicidal ideation/behaviours, insomnia, cognitive deficits, and irritability. |
2023-06-29 |
2023-08-14 |
Not clear |
| Federica Lucantonio, Shuwen Li, Jaden Lu, Jacob Roeglin, Leonardo Bontempi, Brenda C Shields, Carlos A Zarate, Michael R Tadross, Marco Pignatell. Ketamine rescues anhedonia by cell-type and input specific adaptations in the Nucleus Accumbens. bioRxiv : the preprint server for biology. 2023-06-19. PMID:37333325. |
here, we show that the nucleus accumbens (nac), a major hub of the reward circuitry, is essential for ketamine's effect in rescuing anhedonia in mice subjected to chronic stress, a critical risk factor in the genesis of depression in humans. |
2023-06-19 |
2023-08-14 |
mouse |
| Eric L Garland, Spencer T Fix, Justin P Hudak, Edward M Bernat, Yoshio Nakamura, Adam W Hanley, Gary W Donaldson, William R Marchand, Brett Froelige. Mindfulness-Oriented Recovery Enhancement remediates anhedonia in chronic opioid use by enhancing neurophysiological responses during savoring of natural rewards. Psychological medicine. vol 53. issue 5. 2023-06-13. PMID:37310337. |
yet, there are no known efficacious treatments for anhedonia and reward deficits associated with chronic opioid use. |
2023-06-13 |
2023-08-14 |
Not clear |