| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Rachel D Phillips, Erin C Walsh, Nicole R Zürcher, David S Lalush, Jessica L Kinard, Chieh-En Tseng, Paul M Cernasov, Delia Kan, Kaitlin Cummings, Lisalynn Kelley, David Campbell, Daniel G Dillon, Diego A Pizzagalli, David Izquierdo-Garcia, Jacob M Hooker, Moria J Smoski, Gabriel S Dichte. Striatal dopamine in anhedonia: A simultaneous [ Psychiatry research. Neuroimaging. vol 333. 2023-06-10. PMID:37301129. |
the purpose of this study was to examine linkages between striatal da, reward circuitry functioning, anhedonia, and, in an exploratory fashion, self-reported stress, in a transdiagnostic anhedonic sample. |
2023-06-10 |
2023-08-14 |
Not clear |
| Zhaosong Chu, Lijin Yuan, Mengxin He, Yuqi Cheng, Yi Lu, Xiufeng Xu, Zonglin She. Atrophy of bilateral nucleus accumbens in melancholic depression. Neuroreport. vol 34. issue 10. 2023-06-04. PMID:37270840. |
meanwhile, it was also suggested that abnormalities in the reward circuit might be closely associated with the symptom of anhedonia of depression. |
2023-06-04 |
2023-08-14 |
human |
| Meghan M Bennett, Kaley E Davis, Jacklynn M Fitzgeral. Neural Correlates of Reward Processing in the Onset, Maintenance, and Treatment of Posttraumatic Stress Disorder. Biological psychiatry. Cognitive neuroscience and neuroimaging. 2023-06-01. PMID:37263417. |
significantly, over 60% of ptsd individuals experience anhedonia, or an inability to feel pleasure, while anhedonia may reflect reward processing deficits. |
2023-06-01 |
2023-08-14 |
Not clear |
| Miranda L Beltzer, Katharine E Daniel, Alexander R Daros, Bethany A Teachma. Examining social reinforcement learning in social anxiety. Journal of behavior therapy and experimental psychiatry. vol 80. 2023-05-29. PMID:37247976. |
reinforcement learning biases have been empirically linked to anhedonia in depression and theoretically linked to social anhedonia in social anxiety disorder, but little work has directly assessed how socially anxious individuals learn from social reward and punishment. |
2023-05-29 |
2023-08-14 |
Not clear |
| Xuan Wang, Yinghao Zhang, Jia Huang, Yi Wang, Yanzhe Niu, Simon S Y Lui, Li Hui, Raymond C K Cha. Revisiting reward impairments in schizophrenia spectrum disorders: a systematic review and meta-analysis for neuroimaging findings. Psychological medicine. 2023-03-30. PMID:36994747. |
abnormal reward functioning is central to anhedonia and amotivation symptoms of schizophrenia (scz). |
2023-03-30 |
2023-08-14 |
Not clear |
| Melissa J M Walsh, Kathryn Gibson, Megan Hynd, Tory A Eisenlohr-Moul, Erin C Walsh, Lauren Schiff, Fred Jarskog, David Lalush, Gabriel S Dichter, Crystal E Schille. Perimenopausal Effects of Estradiol on Anhedonia and Psychosis Study (PEEPs): study protocol for a neural and molecular mechanistic clinical trial. Trials. vol 24. issue 1. 2023-03-01. PMID:36855177. |
estrogen fluctuations may disrupt function in the mesolimbic reward system in some women, leading to psychiatric symptoms like anhedonia or psychosis. |
2023-03-01 |
2023-08-14 |
Not clear |
| Melissa J M Walsh, Kathryn Gibson, Megan Hynd, Tory A Eisenlohr-Moul, Erin C Walsh, Lauren Schiff, Fred Jarskog, David Lalush, Gabriel S Dichter, Crystal E Schille. Perimenopausal Effects of Estradiol on Anhedonia and Psychosis Study (PEEPs): study protocol for a neural and molecular mechanistic clinical trial. Trials. vol 24. issue 1. 2023-03-01. PMID:36855177. |
the perimenopausal effects of estradiol on anhedonia and psychosis study (peeps) is a mechanistic clinical trial that aims to (1) identify relationships between perimenopausal-onset anhedonia and psychosis and neuromolecular markers of mesolimbic reward responses and (2) determine the extent to which estradiol treatment-induced changes in mesolimbic reward responses are associated with alleviation of perimenopausal onset anhedonia or psychosis. |
2023-03-01 |
2023-08-14 |
Not clear |
| Anna-Lena Frey, M Siyabend Kaya, Irina Adeniyi, Ciara McCab. Anhedonia in Relation to Reward and Effort Learning in Young People with Depression Symptoms. Brain sciences. vol 13. issue 2. 2023-02-25. PMID:36831884. |
anhedonia in relation to reward and effort learning in young people with depression symptoms. |
2023-02-25 |
2023-08-14 |
human |
| Anna-Lena Frey, M Siyabend Kaya, Irina Adeniyi, Ciara McCab. Anhedonia in Relation to Reward and Effort Learning in Young People with Depression Symptoms. Brain sciences. vol 13. issue 2. 2023-02-25. PMID:36831884. |
anhedonia, a central depression symptom, is associated with impairments in reward processing. |
2023-02-25 |
2023-08-14 |
human |
| Anna-Lena Frey, M Siyabend Kaya, Irina Adeniyi, Ciara McCab. Anhedonia in Relation to Reward and Effort Learning in Young People with Depression Symptoms. Brain sciences. vol 13. issue 2. 2023-02-25. PMID:36831884. |
however, it is not well understood which sub-components of reward processing (anticipation, motivation, consummation, and learning) are impaired in association with anhedonia in depression. |
2023-02-25 |
2023-08-14 |
human |
| Anna-Lena Frey, M Siyabend Kaya, Irina Adeniyi, Ciara McCab. Anhedonia in Relation to Reward and Effort Learning in Young People with Depression Symptoms. Brain sciences. vol 13. issue 2. 2023-02-25. PMID:36831884. |
to our knowledge, this is the first study observing an association of anhedonia with reward liking, wanting, and learning when reward and effort learning are measured simultaneously. |
2023-02-25 |
2023-08-14 |
human |
| Brandon W Hughes, Benjamin M Siemsen, Evgeny Tsvetkov, Stefano Berto, Jaswinder Kumar, Rebecca G Cornbrooks, Rose Marie Akiki, Jennifer Y Cho, Jordan S Carter, Kirsten K Snyder, Ahlem Assali, Michael D Scofield, Christopher W Cowan, Makoto Taniguch. NPAS4 in the medial prefrontal cortex mediates chronic social defeat stress-induced anhedonia-like behavior and reductions in excitatory synapses. eLife. vol 12. 2023-02-13. PMID:36780219. |
chronic stress can produce reward system deficits (i.e., anhedonia) and other common symptoms associated with depressive disorders, as well as neural circuit hypofunction in the medial prefrontal cortex (mpfc). |
2023-02-13 |
2023-08-14 |
mouse |
| Paola Castellano, Valeria Gigli, Valerio Ghezzi, Yuen-Siang Ang, Martino Schettino, Diego A Pizzagalli, Cristina Ottavian. Momentary gustative-olfactory sensitivity and tonic heart rate variability are independently associated with motivational behavior. International journal of psychophysiology : official journal of the International Organization of Psychophysiology. 2023-02-04. PMID:36738932. |
the present study examined the putative associations between loss of smell (anosmia) and taste (ageusia) sensitivity, irrespective of covid-19 infection, and anhedonia, measured by a signal-detection task probing the ability to modify behavior as a function of rewards (probabilistic reward task; prt). |
2023-02-04 |
2023-08-14 |
Not clear |
| Chloe C Boyle, Steve W Cole, Michael R Irwin, Naomi I Eisenberger, Julienne E Bowe. The role of inflammation in acute psychosocial stress-induced modulation of reward processing in healthy female adults. Brain, behavior, & immunity - health. vol 28. 2023-01-23. PMID:36683947. |
anhedonia, or loss of interest and pleasure, is a pernicious symptom of depression that involves deficits in reward processing. |
2023-01-23 |
2023-08-14 |
Not clear |
| Kevin G Saulnier, Natalie S Marr, Camilla van Geen, Dara E Babinski, Dahlia Mukherje. Reinforcement-based responsiveness, depression, and anhedonia: A multi-method investigation of intergenerational risk. Journal of psychiatric research. vol 158. 2023-01-15. PMID:36641974. |
the current study was designed to investigate the intergenerational relations between maternal markers of reward and punishment responsiveness and their offspring's depression and anhedonia in a community sample of 40 mother (mean age = 44.5; sd = 6.82) and adolescent (mean age = 14.73; sd = 1.25; 52.5% female) dyads. |
2023-01-15 |
2023-08-14 |
Not clear |
| Kevin G Saulnier, Natalie S Marr, Camilla van Geen, Dara E Babinski, Dahlia Mukherje. Reinforcement-based responsiveness, depression, and anhedonia: A multi-method investigation of intergenerational risk. Journal of psychiatric research. vol 158. 2023-01-15. PMID:36641974. |
maternal markers of reward and punishment responsiveness were captured using self-report, behavioral, and neurophysiological methods, and self-reported depression and anhedonia symptoms were used as outcomes among the adolescent offspring. |
2023-01-15 |
2023-08-14 |
Not clear |
| Kate R Kuhlman, Steve W Cole, Michael R Irwin, Michelle G Craske, Andrew J Fuligni, Julienne E Bowe. The role of early life adversity and inflammation in stress-induced change in reward and risk processes among adolescents. Brain, behavior, and immunity. 2023-01-09. PMID:36621653. |
the neuroimmune network hypothesis posits that ela increases sensitivity to psychosocial stress, moderating the association between increases in peripheral markers of inflammation and decreases in reward outcomes linked to anhedonia and risk-taking behaviors. |
2023-01-09 |
2023-08-14 |
Not clear |
| Hong Zhou, Jiayu Zhu, Jie Jia, Wei Xiang, Hualing Peng, Yuejin Zhang, Bo Liu, Yangling Mu, Yisheng L. The antidepressant effect of nucleus accumbens deep brain stimulation is mediated by parvalbumin-positive interneurons in the dorsal dentate gyrus. Neurobiology of stress. vol 21. 2022-12-19. PMID:36532368. |
the nucleus accumbens (nac) is a crucial region in the reward circuit and is related to anhedonia, the pivotal symptom of major depression disorder (mdd). |
2022-12-19 |
2023-08-14 |
mouse |
| Astrid M Cardona-Acosta, Carlos A Bolaños-Guzmá. Role of the mesolimbic dopamine pathway in the antidepressant effects of ketamine. Neuropharmacology. 2022-12-14. PMID:36516891. |
exposure to negative stress dysregulates dopamine neuronal activity disrupting reward and motivational processes resulting in anhedonia (lack of pleasure), a hallmark symptom of depression. |
2022-12-14 |
2023-08-14 |
Not clear |
| Adrià Vilà-Balló, Myriam De la Cruz-Puebla, Diana López-Barroso, Júlia Miró, Jacint Sala-Padró, David Cucurell, Mercè Falip, Antoni Rodríguez-Fornell. Reward-based decision-making in mesial temporal lobe epilepsy patients with unilateral hippocampal sclerosis pre- and post-surgery. NeuroImage. Clinical. vol 36. 2022-12-13. PMID:36510413. |
correct functioning of the reward processing system is critical for optimizing decision-making as well as preventing the development of addictions and/or neuropsychiatric symptoms such as depression, apathy, and anhedonia. |
2022-12-13 |
2023-08-14 |
Not clear |